Project measure / variable:   Eumorphia7   IgA

ID, description, units MPD:29606   IgA   immunoglobulin A (serum IgA)   [µg/mL]  
Data set, strains Eumorphia7   inbred   6 strains     sex: both     age: 9-12wks
Procedure immunoglobulin quantification
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  STRAIN COMPARISON PLOT
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Eumorphia7 - immunoglobulin A (serum IgA)



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested6 strains5 strains
Mean of the strain means16.1   µg/mL 10.7   µg/mL
Median of the strain means10.6   µg/mL 12.0   µg/mL
SD of the strain means± 17.6 ± 3.67
Coefficient of variation (CV)1.09 0.344
Min–max range of strain means2.82   –   51.4   µg/mL 5.06   –   14.6   µg/mL
Mean sample size per strain5.0   mice 5.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 32.3208 32.3208 16.7526 0.0002
strain 4 554.2228 138.5557 71.8166 < 0.0001
sex:strain 4 3.6292 0.9073 0.4703 0.7572
Residuals 40 77.172 1.9293


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129P2/OlaHsd f 51.4 14.8   5 6.63 0.288 30.0, 65.0 2.0
BALB/cByJ f 8.5 0.5   5 0.224 0.0588 8.0, 9.0 -0.43
BALB/cByJ m 9.22 0.861   5 0.385 0.0934 8.0, 10.1 -0.39
BALB/cJ f 11.1 0.548   5 0.245 0.0493 10.5, 12.0 -0.28
BALB/cJ m 12.4 0.652   5 0.292 0.0526 11.5, 13.0 0.48
C3H/HeNCrl f 10.1 0.942   5 0.421 0.0934 8.5, 11.0 -0.34
C3H/HeNCrl m 12.0 0.555   5 0.248 0.0461 11.5, 12.7 0.37
C57BL/6J f 2.82 0.87   5 0.389 0.309 1.7, 4.0 -0.75
C57BL/6J m 5.06 3.02   5 1.35 0.598 2.0, 8.5 -1.53
CBA/J f 12.7 1.32   5 0.59 0.103 10.5, 14.0 -0.19
CBA/J m 14.6 2.18   5 0.974 0.15 12.0, 18.0 1.08


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BALB/cByJ f 8.5 0.6212 9.7554 7.2446
BALB/cByJ m 9.22 0.6212 10.4754 7.9646
BALB/cJ f 11.1 0.6212 12.3554 9.8446
BALB/cJ m 12.4 0.6212 13.6554 11.1446
C3H/HeNCrl f 10.08 0.6212 11.3354 8.8246
C3H/HeNCrl m 12.04 0.6212 13.2954 10.7846
C57BL/6J f 2.82 0.6212 4.0754 1.5646
C57BL/6J m 5.06 0.6212 6.3154 3.8046
CBA/J f 12.74 0.6212 13.9954 11.4846
CBA/J m 14.56 0.6212 15.8154 13.3046


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
BALB/cByJ both 8.86 0.4392 9.7477 7.9723
BALB/cJ both 11.75 0.4392 12.6377 10.8623
C3H/HeNCrl both 11.06 0.4392 11.9477 10.1723
C57BL/6J both 3.94 0.4392 4.8277 3.0523
CBA/J both 13.65 0.4392 14.5377 12.7623




  GWAS USING LINEAR MIXED MODELS