Project measure / variable:   Xing1   QT_M12

ID, description, units MPD:24932   QT_M12   interval QT   [ms]  at age 12mo  
Data set, strains Xing1   inbred   28 strains     sex: both     age: 52wks
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  STRAIN COMPARISON PLOT
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Xing1 - interval QT at age 12mo



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested27 strains27 strains
Mean of the strain means43.6   ms 43.5   ms
Median of the strain means43.3   ms 43.6   ms
SD of the strain means± 2.19 ± 2.08
Coefficient of variation (CV)0.0503 0.0479
Min–max range of strain means38.8   –   49.3   ms 38.6   –   48.2   ms
Mean sample size per strain7.5   mice 7.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.0749 0.0749 0.0062 0.9375
strain 25 1164.8108 46.5924 3.829 < 0.0001
sex:strain 25 484.6077 19.3843 1.593 0.0376
Residuals 338 4112.935 12.1684


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 46.2 2.82   8 0.995 0.0609 41.6, 49.8 1.18
129S1/SvImJ m 43.6 6.46   8 2.28 0.148 28.7, 49.8 0.03
A/J f 44.5 4.85   7 1.83 0.109 38.4, 51.9 0.41
A/J m 45.3 2.75   7 1.04 0.0608 42.5, 49.5 0.84
AKR/J f 49.3 17.9   4 8.96 0.364 39.0, 76.0 2.6
AKR/J m 40.2 2.61   5 1.17 0.0649 38.4, 44.3 -1.6
BALB/cByJ f 43.2 2.48   6 1.01 0.0573 39.2, 45.8 -0.18
BALB/cByJ m 46.0 3.97   8 1.4 0.0865 42.7, 55.4 1.18
BTBR T+ Itpr3tf/J f 41.4 1.82   8 0.643 0.044 39.0, 43.3 -1.0
BTBR T+ Itpr3tf/J m 42.9 2.11   8 0.746 0.0492 40.0, 46.7 -0.31
BUB/BnJ f 41.1 2.17   7 0.821 0.0528 38.3, 43.8 -1.14
BUB/BnJ m 40.9 2.49   8 0.879 0.0607 36.6, 43.6 -1.27
C3H/HeJ f 38.8 2.84   8 1.0 0.0731 34.9, 42.6 -2.19
C3H/HeJ m 38.6 3.16   8 1.12 0.0819 33.1, 42.3 -2.37
C57BL/10J f 44.4 2.56   8 0.906 0.0576 41.6, 49.3 0.36
C57BL/10J m 42.5 2.52   8 0.893 0.0594 37.7, 46.3 -0.5
C57BL/6J f 43.0 2.34   7 0.885 0.0545 40.0, 47.3 -0.28
C57BL/6J m 43.1 1.03   8 0.364 0.0239 41.7, 44.9 -0.21
C57BLKS/J f 43.3 1.9   8 0.67 0.0438 40.7, 46.3 -0.14
C57BLKS/J m 45.4 1.17   8 0.413 0.0257 43.1, 46.9 0.89
C57BR/cdJ f 43.1 1.73   6 0.708 0.0402 40.5, 45.5 -0.23
C57BR/cdJ m 43.2 1.12   8 0.396 0.0259 41.4, 44.6 -0.17
C57L/J f 44.4 1.54   7 0.583 0.0347 42.4, 46.6 0.36
C57L/J m 43.8 1.62   8 0.573 0.037 41.8, 46.7 0.12
CBA/J f 44.1 3.72   8 1.32 0.0844 38.9, 49.1 0.23
CBA/J m 44.0 5.65   8 2.0 0.128 33.7, 51.5 0.22
DBA/2J f 42.4 2.09   7 0.79 0.0493 40.1, 45.5 -0.55
DBA/2J m 43.1 2.62   8 0.927 0.0609 40.1, 48.4 -0.21
FVB/NJ f 43.0 4.59   8 1.62 0.107 37.3, 49.9 -0.28
FVB/NJ m 43.1 3.12   8 1.1 0.0724 38.1, 48.0 -0.21
KK/HlJ f 42.1 2.88   8 1.02 0.0685 38.7, 47.2 -0.69
KK/HlJ m 42.3 2.34   9 0.779 0.0553 39.4, 45.5 -0.6
LP/J f 42.0 2.01   7 0.759 0.0478 39.5, 45.6 -0.73
LP/J m 43.7 2.07   8 0.733 0.0475 41.1, 46.8 0.07
MRL/MpJ f 45.3 3.12   7 1.18 0.0688 41.4, 50.8 0.77
MRL/MpJ m 42.2 4.9   6 2.0 0.116 34.4, 49.3 -0.64
NOD.B10Sn-H2b/J f 41.5 2.29   10 0.725 0.0553 38.6, 45.7 -0.96
NOD.B10Sn-H2b/J m 40.9 2.38   8 0.84 0.0582 38.4, 44.6 -1.27
NON/ShiLtJ f 45.1 2.76   7 1.04 0.0613 40.9, 47.8 0.68
NON/ShiLtJ m 48.2 3.67   8 1.3 0.0761 41.7, 53.0 2.23
NZO/HlLtJ f 44.3 4.7   9 1.57 0.106 39.9, 54.5 0.32
NZO/HlLtJ m 47.1 4.04   5 1.81 0.0859 41.3, 52.5 1.71
NZW/LacJ f 44.2 3.82   8 1.35 0.0863 38.4, 49.2 0.27
NZW/LacJ m 45.7 3.51   7 1.33 0.0769 41.7, 51.5 1.03
P/J m 44.1 3.41   6 1.39 0.0774 38.4, 48.3 0.27
PL/J f 42.5 2.53   8 0.896 0.0596 37.6, 45.6 -0.5
PL/J m 44.0 1.88   7 0.71 0.0427 41.2, 46.9 0.22
RIIIS/J f 48.7 5.29   7 2.0 0.109 41.8, 54.5 2.32
RIIIS/J m 45.3 2.12   8 0.75 0.0469 40.4, 47.0 0.84
SJL/J f 43.7 5.73   8 2.02 0.131 35.2, 54.9 0.04
SM/J f 44.1 1.37   7 0.517 0.031 42.3, 46.1 0.23
SM/J m 42.2 3.02   8 1.07 0.0715 36.8, 45.4 -0.64
SWR/J f 41.6 1.4   8 0.493 0.0335 39.8, 43.9 -0.91
SWR/J m 44.3 2.19   7 0.829 0.0495 41.7, 48.2 0.36


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 46.2125 1.2333 48.6384 43.7866
129S1/SvImJ m 43.6125 1.2333 46.0384 41.1866
A/J f 44.5 1.3185 47.0934 41.9066
A/J m 45.3429 1.3185 47.9363 42.7494
AKR/J f 49.275 1.7442 52.7058 45.8442
AKR/J m 40.22 1.56 43.2886 37.1514
BALB/cByJ f 43.25 1.4241 46.0512 40.4488
BALB/cByJ m 45.9625 1.2333 48.3884 43.5366
BTBR T+ Itpr3tf/J f 41.3625 1.2333 43.7884 38.9366
BTBR T+ Itpr3tf/J m 42.8625 1.2333 45.2884 40.4366
BUB/BnJ f 41.1429 1.3185 43.7363 38.5494
BUB/BnJ m 40.9375 1.2333 43.3634 38.5116
C3H/HeJ f 38.8125 1.2333 41.2384 36.3866
C3H/HeJ m 38.5625 1.2333 40.9884 36.1366
C57BL/10J f 44.4375 1.2333 46.8634 42.0116
C57BL/10J m 42.4875 1.2333 44.9134 40.0616
C57BL/6J f 42.9857 1.3185 45.5791 40.3923
C57BL/6J m 43.0625 1.2333 45.4884 40.6366
C57BLKS/J f 43.325 1.2333 45.7509 40.8991
C57BLKS/J m 45.45 1.2333 47.8759 43.0241
C57BR/cdJ f 43.1167 1.4241 45.9179 40.3154
C57BR/cdJ m 43.2125 1.2333 45.6384 40.7866
C57L/J f 44.4286 1.3185 47.022 41.8351
C57L/J m 43.7875 1.2333 46.2134 41.3616
CBA/J f 44.1375 1.2333 46.5634 41.7116
CBA/J m 43.9625 1.2333 46.3884 41.5366
DBA/2J f 42.3857 1.3185 44.9791 39.7923
DBA/2J m 43.0625 1.2333 45.4884 40.6366
FVB/NJ f 43.0375 1.2333 45.4634 40.6116
FVB/NJ m 43.125 1.2333 45.5509 40.6991
KK/HlJ f 42.075 1.2333 44.5009 39.6491
KK/HlJ m 42.2778 1.1628 44.565 39.9906
LP/J f 42.0 1.3185 44.5934 39.4066
LP/J m 43.65 1.2333 46.0759 41.2241
MRL/MpJ f 45.3429 1.3185 47.9363 42.7494
MRL/MpJ m 42.2167 1.4241 45.0179 39.4154
NOD.B10Sn-H2b/J f 41.49 1.1031 43.6598 39.3202
NOD.B10Sn-H2b/J m 40.85 1.2333 43.2759 38.4241
NON/ShiLtJ f 45.0857 1.3185 47.6791 42.4923
NON/ShiLtJ m 48.175 1.2333 50.6009 45.7491
NZO/HlLtJ f 44.3444 1.1628 46.6316 42.0573
NZO/HlLtJ m 47.1 1.56 50.1686 44.0314
NZW/LacJ f 44.2125 1.2333 46.6384 41.7866
NZW/LacJ m 45.6571 1.3185 48.2506 43.0637
PL/J f 42.525 1.2333 44.9509 40.0991
PL/J m 43.9857 1.3185 46.5791 41.3923
RIIIS/J f 48.6571 1.3185 51.2506 46.0637
RIIIS/J m 45.3 1.2333 47.7259 42.8741
SM/J f 44.1 1.3185 46.6934 41.5066
SM/J m 42.175 1.2333 44.6009 39.7491
SWR/J f 41.625 1.2333 44.0509 39.1991
SWR/J m 44.2714 1.3185 46.8649 41.678


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 44.9125 0.8721 46.6279 43.1971
A/J both 44.9214 0.9323 46.7553 43.0876
AKR/J both 44.7475 1.17 47.0489 42.4461
BALB/cByJ both 44.6063 0.942 46.4591 42.7534
BTBR T+ Itpr3tf/J both 42.1125 0.8721 43.8279 40.3971
BUB/BnJ both 41.0402 0.9027 42.8158 39.2646
C3H/HeJ both 38.6875 0.8721 40.4029 36.9721
C57BL/10J both 43.4625 0.8721 45.1779 41.7471
C57BL/6J both 43.0241 0.9027 44.7997 41.2485
C57BLKS/J both 44.3875 0.8721 46.1029 42.6721
C57BR/cdJ both 43.1646 0.942 45.0174 41.3117
C57L/J both 44.108 0.9027 45.8836 42.3324
CBA/J both 44.05 0.8721 45.7654 42.3346
DBA/2J both 42.7241 0.9027 44.4997 40.9485
FVB/NJ both 43.0813 0.8721 44.7966 41.3659
KK/HlJ both 42.1764 0.8475 43.8435 40.5093
LP/J both 42.825 0.9027 44.6006 41.0494
MRL/MpJ both 43.7798 0.9704 45.6885 41.871
NOD.B10Sn-H2b/J both 41.17 0.8273 42.7974 39.5426
NON/ShiLtJ both 46.6304 0.9027 48.406 44.8548
NZO/HlLtJ both 45.7222 0.9728 47.6358 43.8086
NZW/LacJ both 44.9348 0.9027 46.7104 43.1592
PL/J both 43.2554 0.9027 45.031 41.4798
RIIIS/J both 46.9786 0.9027 48.7542 45.203
SM/J both 43.1375 0.9027 44.9131 41.3619
SWR/J both 42.9482 0.9027 44.7238 41.1726




  GWAS USING LINEAR MIXED MODELS