Project measure / variable:   Xing1   QT_M06

ID, description, units MPD:24931   QT_M06   interval QT   [ms]  at age 6mo  
Data set, strains Xing1   inbred   28 strains     sex: both     age: 26wks
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  STRAIN COMPARISON PLOT
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Xing1 - interval QT at age 6mo



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested28 strains27 strains
Mean of the strain means42.9   ms 42.4   ms
Median of the strain means42.6   ms 42.5   ms
SD of the strain means± 2.14 ± 2.33
Coefficient of variation (CV)0.0499 0.0550
Min–max range of strain means38.4   –   48.6   ms 37.4   –   48.2   ms
Mean sample size per strain7.5   mice 7.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 40.7045 40.7045 4.0268 0.0456
strain 26 1770.331 68.0897 6.7359 < 0.0001
sex:strain 26 204.6989 7.873 0.7789 0.7745
Residuals 348 3517.7638 10.1085


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 42.6 3.82   8 1.35 0.0897 38.6, 49.5 -0.14
129S1/SvImJ m 43.1 4.77   7 1.8 0.111 36.5, 50.6 0.32
A/J f 45.8 3.61   8 1.28 0.0789 43.1, 52.0 1.35
A/J m 45.3 7.36   8 2.6 0.162 38.1, 61.6 1.26
AKR/J f 41.4 1.78   8 0.63 0.0431 38.6, 43.4 -0.7
AKR/J m 43.0 2.33   7 0.881 0.0542 39.9, 47.2 0.28
BALB/cByJ f 44.0 2.85   7 1.08 0.0649 40.3, 49.1 0.51
BALB/cByJ m 45.2 1.75   8 0.619 0.0387 42.2, 47.8 1.22
BTBR T+ Itpr3tf/J f 41.7 3.05   6 1.25 0.0731 36.6, 44.8 -0.56
BUB/BnJ f 39.2 3.83   7 1.45 0.0978 33.5, 43.2 -1.73
BUB/BnJ m 39.8 2.99   7 1.13 0.0752 35.4, 43.5 -1.1
C3H/HeJ f 38.4 3.72   8 1.31 0.0967 34.6, 45.0 -2.1
C3H/HeJ m 37.8 2.6   7 0.983 0.0688 34.5, 41.6 -1.96
C57BL/10J f 44.1 4.74   7 1.79 0.107 37.0, 49.8 0.56
C57BL/10J m 42.5 1.35   8 0.477 0.0318 40.4, 44.5 0.06
C57BL/6J f 42.6 1.74   8 0.616 0.0409 40.1, 45.1 -0.14
C57BL/6J m 42.2 1.37   8 0.485 0.0325 40.5, 44.7 -0.07
C57BLKS/J f 45.8 3.78   8 1.34 0.0827 41.1, 53.1 1.35
C57BLKS/J m 45.3 1.86   7 0.701 0.0409 42.9, 47.7 1.26
C57BR/cdJ f 42.7 1.94   7 0.733 0.0454 40.0, 45.2 -0.1
C57BR/cdJ m 43.0 2.47   7 0.935 0.0575 38.3, 45.4 0.28
C57L/J f 42.4 0.959   8 0.339 0.0226 41.0, 43.5 -0.24
C57L/J m 41.8 1.33   8 0.469 0.0318 39.5, 43.9 -0.24
CBA/J f 41.9 2.63   7 0.992 0.0626 38.3, 46.8 -0.47
CBA/J m 42.7 1.54   8 0.545 0.0361 39.8, 44.4 0.15
DBA/2J f 42.5 2.09   8 0.741 0.0492 40.4, 45.5 -0.19
DBA/2J m 40.4 2.95   8 1.04 0.0729 37.1, 45.4 -0.84
FVB/NJ f 41.3 2.57   8 0.908 0.0622 37.2, 45.1 -0.75
FVB/NJ m 39.4 1.35   7 0.512 0.0344 37.6, 41.3 -1.27
KK/HlJ f 43.7 2.75   8 0.974 0.0631 40.1, 48.3 0.37
KK/HlJ m 42.5 3.77   8 1.33 0.0888 35.6, 46.2 0.06
LP/J f 42.4 2.85   6 1.16 0.0672 38.1, 46.5 -0.24
LP/J m 41.5 2.31   8 0.816 0.0556 38.4, 45.2 -0.37
MRL/MpJ f 44.3 3.17   6 1.3 0.0717 39.9, 49.1 0.65
MRL/MpJ m 40.4 2.08   8 0.734 0.0514 38.0, 43.3 -0.84
NOD.B10Sn-H2b/J f 40.0 2.56   6 1.04 0.0639 37.0, 44.1 -1.36
NOD.B10Sn-H2b/J m 41.9 2.26   4 1.13 0.0541 39.1, 44.2 -0.2
NON/ShiLtJ f 44.4 2.15   8 0.759 0.0483 40.8, 47.6 0.7
NON/ShiLtJ m 43.0 5.83   8 2.06 0.136 31.7, 49.7 0.28
NZO/HlLtJ f 43.9 2.62   8 0.925 0.0596 40.4, 48.7 0.46
NZO/HlLtJ m 43.5 3.04   7 1.15 0.0699 39.3, 47.7 0.49
NZW/LacJ f 45.6 7.05   8 2.49 0.155 37.5, 59.4 1.26
NZW/LacJ m 44.8 3.94   7 1.49 0.0881 40.0, 52.5 1.05
P/J f 41.6 1.44   5 0.644 0.0346 39.0, 42.4 -0.61
P/J m 43.3 0.865   7 0.327 0.02 42.0, 44.2 0.4
PL/J f 42.2 1.84   10 0.583 0.0436 39.0, 44.9 -0.33
PL/J m 41.4 2.76   5 1.23 0.0666 37.2, 44.9 -0.41
RIIIS/J f 48.6 5.67   8 2.0 0.117 41.7, 58.7 2.66
RIIIS/J m 48.2 3.22   7 1.22 0.0668 42.6, 52.6 2.51
SJL/J f 41.0 3.19   8 1.13 0.0779 36.7, 45.7 -0.89
SJL/J m 37.4 1.69   8 0.596 0.0451 36.1, 41.4 -2.13
SM/J f 44.5 2.04   8 0.721 0.0458 42.1, 47.5 0.74
SM/J m 41.5 3.01   8 1.06 0.0725 37.8, 45.2 -0.37
SWR/J f 42.8 1.86   8 0.658 0.0436 40.1, 45.8 -0.05
SWR/J m 42.8 3.25   8 1.15 0.076 38.2, 48.0 0.19


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 42.5625 1.1241 44.7734 40.3516
129S1/SvImJ m 43.1143 1.2017 45.4778 40.7508
A/J f 45.7625 1.1241 47.9734 43.5516
A/J m 45.3375 1.1241 47.5484 43.1266
AKR/J f 41.3625 1.1241 43.5734 39.1516
AKR/J m 43.0286 1.2017 45.3921 40.6651
BALB/cByJ f 44.0 1.2017 46.3635 41.6365
BALB/cByJ m 45.25 1.1241 47.4609 43.0391
BUB/BnJ f 39.2143 1.2017 41.5778 36.8508
BUB/BnJ m 39.8 1.2017 42.1635 37.4365
C3H/HeJ f 38.4125 1.1241 40.6234 36.2016
C3H/HeJ m 37.7857 1.2017 40.1492 35.4222
C57BL/10J f 44.0857 1.2017 46.4492 41.7222
C57BL/10J m 42.45 1.1241 44.6609 40.2391
C57BL/6J f 42.5625 1.1241 44.7734 40.3516
C57BL/6J m 42.1875 1.1241 44.3984 39.9766
C57BLKS/J f 45.775 1.1241 47.9859 43.5641
C57BLKS/J m 45.3143 1.2017 47.6778 42.9508
C57BR/cdJ f 42.6857 1.2017 45.0492 40.3222
C57BR/cdJ m 43.0429 1.2017 45.4064 40.6794
C57L/J f 42.45 1.1241 44.6609 40.2391
C57L/J m 41.7625 1.1241 43.9734 39.5516
CBA/J f 41.9286 1.2017 44.2921 39.5651
CBA/J m 42.7 1.1241 44.9109 40.4891
DBA/2J f 42.5375 1.1241 44.7484 40.3266
DBA/2J m 40.45 1.1241 42.6609 38.2391
FVB/NJ f 41.2875 1.1241 43.4984 39.0766
FVB/NJ m 39.3714 1.2017 41.7349 37.0079
KK/HlJ f 43.675 1.1241 45.8859 41.4641
KK/HlJ m 42.5 1.1241 44.7109 40.2891
LP/J f 42.4167 1.298 44.9695 39.8638
LP/J m 41.5375 1.1241 43.7484 39.3266
MRL/MpJ f 44.3 1.298 46.8529 41.7471
MRL/MpJ m 40.375 1.1241 42.5859 38.1641
NOD.B10Sn-H2b/J f 40.0167 1.298 42.5695 37.4638
NOD.B10Sn-H2b/J m 41.85 1.5897 44.9766 38.7234
NON/ShiLtJ f 44.425 1.1241 46.6359 42.2141
NON/ShiLtJ m 42.975 1.1241 45.1859 40.7641
NZO/HlLtJ f 43.925 1.1241 46.1359 41.7141
NZO/HlLtJ m 43.4857 1.2017 45.8492 41.1222
NZW/LacJ f 45.5625 1.1241 47.7734 43.3516
NZW/LacJ m 44.7714 1.2017 47.1349 42.4079
P/J f 41.56 1.4219 44.3565 38.7635
P/J m 43.3143 1.2017 45.6778 40.9508
PL/J f 42.25 1.0054 44.2274 40.2726
PL/J m 41.42 1.4219 44.2165 38.6235
RIIIS/J f 48.5875 1.1241 50.7984 46.3766
RIIIS/J m 48.2286 1.2017 50.5921 45.8651
SJL/J f 40.9625 1.1241 43.1734 38.7516
SJL/J m 37.3875 1.1241 39.5984 35.1766
SM/J f 44.5375 1.1241 46.7484 42.3266
SM/J m 41.55 1.1241 43.7609 39.3391
SWR/J f 42.75 1.1241 44.9609 40.5391
SWR/J m 42.775 1.1241 44.9859 40.5641


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 42.8384 0.8227 44.4566 41.2202
A/J both 45.55 0.7948 47.1133 43.9867
AKR/J both 42.1955 0.8227 43.8137 40.5774
BALB/cByJ both 44.625 0.8227 46.2432 43.0068
BUB/BnJ both 39.5071 0.8497 41.1784 37.8359
C3H/HeJ both 38.0991 0.8227 39.7173 36.4809
C57BL/10J both 43.2679 0.8227 44.886 41.6497
C57BL/6J both 42.375 0.7948 43.9383 40.8117
C57BLKS/J both 45.5446 0.8227 47.1628 43.9265
C57BR/cdJ both 42.8643 0.8497 44.5355 41.193
C57L/J both 42.1063 0.7948 43.6696 40.5429
CBA/J both 42.3143 0.8227 43.9325 40.6961
DBA/2J both 41.4938 0.7948 43.0571 39.9304
FVB/NJ both 40.3295 0.8227 41.9476 38.7113
KK/HlJ both 43.0875 0.7948 44.6508 41.5242
LP/J both 41.9771 0.8585 43.6657 40.2885
MRL/MpJ both 42.3375 0.8585 44.0261 40.6489
NOD.B10Sn-H2b/J both 40.9333 1.0261 42.9516 38.9151
NON/ShiLtJ both 43.7 0.7948 45.2633 42.1367
NZO/HlLtJ both 43.7054 0.8227 45.3235 42.0872
NZW/LacJ both 45.167 0.8227 46.7851 43.5488
P/J both 42.4371 0.9308 44.2679 40.6064
PL/J both 41.835 0.8707 43.5475 40.1225
RIIIS/J both 48.408 0.8227 50.0262 46.7899
SJL/J both 39.175 0.7948 40.7383 37.6117
SM/J both 43.0438 0.7948 44.6071 41.4804
SWR/J both 42.7625 0.7948 44.3258 41.1992




  GWAS USING LINEAR MIXED MODELS