Project measure / variable:   Peters4   Retic_M18

ID, description, units MPD:24379   Retic_M18   reticulocyte count (Retic)   [n/L]  at age 18mo  
Data set, strains Peters4   inbred   29 strains     sex: both     age: 78wks
Procedure complete blood count
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  STRAIN COMPARISON PLOT
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Peters4 - reticulocyte count (Retic) at age 18mo



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested25 strains28 strains
Mean of the strain means336   n/L 287   n/L
Median of the strain means305   n/L 285   n/L
SD of the strain means± 86.4 ± 56.4
Coefficient of variation (CV)0.257 0.197
Min–max range of strain means208   –   518   n/L 177   –   405   n/L
Mean sample size per strain7.0   mice 7.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 129265.2424 129265.2424 13.5548 0.0003
strain 23 1167538.9642 50762.5637 5.323 < 0.0001
sex:strain 23 517633.6033 22505.8088 2.36 0.0006
Residuals 299 2851418.4398 9536.5165


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 259.0 66.8   7 25.2 0.258 133.0, 352.0 -0.5
A/J f 305.0 105.0   7 39.7 0.344 199.0, 513.0 -0.36
A/J m 306.0 130.0   13 36.2 0.427 200.0, 662.0 0.34
BALB/cByJ f 271.0 54.8   8 19.4 0.202 209.0, 379.0 -0.75
BALB/cByJ m 299.0 42.5   7 16.1 0.142 235.0, 374.0 0.21
BTBR T+ Itpr3tf/J f 514.0 268.0   8 94.9 0.522 294.0, 961.0 2.06
BTBR T+ Itpr3tf/J m 249.0 46.9   5 21.0 0.188 170.0, 288.0 -0.67
BUB/BnJ f 246.0 28.6   5 12.8 0.116 197.0, 271.0 -1.04
BUB/BnJ m 273.0 18.2   6 7.44 0.0667 245.0, 298.0 -0.25
C57BL/10J f 518.0 231.0   6 94.4 0.446 328.0, 952.0 2.11
C57BL/10J m 324.0 38.4   13 10.7 0.118 251.0, 370.0 0.66
C57BL/6J f 350.0 30.3   7 11.5 0.0867 304.0, 389.0 0.16
C57BL/6J m 342.0 24.2   7 9.14 0.0707 308.0, 374.0 0.98
C57BLKS/J m 298.0 32.3   16 8.08 0.108 217.0, 346.0 0.2
C57BR/cdJ f 351.0 76.0   8 26.9 0.216 246.0, 453.0 0.18
C57BR/cdJ m 401.0 57.0   8 20.1 0.142 335.0, 510.0 2.02
C57L/J f 338.0 65.3   7 24.7 0.193 290.0, 464.0 0.02
C57L/J m 389.0 98.9   7 37.4 0.254 239.0, 548.0 1.81
CAST/EiJ f 302.0 31.3   8 11.1 0.104 273.0, 371.0 -0.39
CBA/J m 177.0 39.8   5 17.8 0.226 141.0, 236.0 -1.95
DBA/2J f 208.0 62.9   6 25.7 0.303 89.6, 264.0 -1.48
DBA/2J m 212.0 6.57   6 2.68 0.031 204.0, 219.0 -1.33
FVB/NJ f 298.0 45.1   7 17.1 0.151 238.0, 362.0 -0.44
FVB/NJ m 319.0 39.1   12 11.3 0.123 264.0, 382.0 0.57
KK/HlJ f 482.0 156.0   6 63.7 0.324 300.0, 643.0 1.69
KK/HlJ m 309.0 54.8   7 20.7 0.178 229.0, 390.0 0.39
LP/J m 232.0 22.6   8 7.98 0.0973 193.0, 263.0 -0.97
MRL/MpJ f 330.0 125.0   7 47.1 0.378 104.0, 506.0 -0.07
MRL/MpJ m 287.0 109.0   8 38.7 0.381 50.5, 396.0 0.0
NOD.B10Sn-H2b/J f 441.0 132.0   6 54.0 0.3 242.0, 573.0 1.22
NOD.B10Sn-H2b/J m 405.0 41.0   6 16.7 0.101 373.0, 458.0 2.09
NON/ShiLtJ f 328.0 74.0   5 33.1 0.226 229.0, 410.0 -0.09
NON/ShiLtJ m 283.0 24.5   7 9.26 0.0864 250.0, 324.0 -0.07
NZO/HlLtJ f 279.0 72.4   10 22.9 0.26 212.0, 437.0 -0.66
NZO/HlLtJ m 255.0 5.66   2   4.0 0.0222 251.0, 259.0 -0.57
NZW/LacJ f 298.0 83.7   7 31.6 0.281 192.0, 445.0 -0.44
NZW/LacJ m 252.0 21.3   6 8.68 0.0843 220.0, 278.0 -0.62
P/J f 270.0 89.9   7 34.0 0.333 151.0, 417.0 -0.76
P/J m 251.0 49.1   5 21.9 0.195 173.0, 305.0 -0.64
PL/J f 457.0 233.0   8 82.3 0.509 276.0, 995.0 1.4
PL/J m 330.0 104.0   9 34.8 0.316 196.0, 573.0 0.76
PWD/PhJ f 277.0 17.6   6 7.19 0.0635 258.0, 299.0 -0.68
PWD/PhJ m 252.0 35.4   7 13.4 0.141 190.0, 304.0 -0.62
RIIIS/J f 279.0 39.4   8 13.9 0.141 239.0, 348.0 -0.66
RIIIS/J m 183.0 16.0   8 5.67 0.0877 162.0, 216.0 -1.84
SJL/J f 377.0 238.0   7 90.0 0.632 176.0, 839.0 0.48
SJL/J m 294.0 34.3   4 17.1 0.117 250.0, 325.0 0.12
SM/J f 234.0 41.6   6 17.0 0.178 186.0, 289.0 -1.18
SM/J m 263.0 29.4   10 9.29 0.112 219.0, 310.0 -0.42
SWR/J f 378.0 77.5   7 29.3 0.205 258.0, 505.0 0.49
SWR/J m 315.0 41.9   8 14.8 0.133 256.0, 393.0 0.5
WSB/EiJ f 265.0 79.4   8 28.1 0.3 167.0, 395.0 -0.82
WSB/EiJ m 276.0 39.2   9 13.1 0.142 240.0, 369.0 -0.19


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J f 305.1429 36.9102 377.7794 232.5063
A/J m 305.5385 27.0846 358.8391 252.2378
BALB/cByJ f 271.375 34.5263 339.3203 203.4297
BALB/cByJ m 299.1429 36.9102 371.7794 226.5063
BTBR T+ Itpr3tf/J f 514.25 34.5263 582.1953 446.3047
BTBR T+ Itpr3tf/J m 248.6 43.6727 334.5448 162.6552
BUB/BnJ f 246.4 43.6727 332.3448 160.4552
BUB/BnJ m 273.1667 39.8675 351.6231 194.7102
C57BL/10J f 517.8333 39.8675 596.2898 439.3769
C57BL/10J m 324.3077 27.0846 377.6084 271.007
C57BL/6J f 350.0 36.9102 422.6366 277.3634
C57BL/6J m 342.2857 36.9102 414.9223 269.6491
C57BR/cdJ f 351.125 34.5263 419.0703 283.1797
C57BR/cdJ m 401.25 34.5263 469.1953 333.3047
C57L/J f 338.0 36.9102 410.6366 265.3634
C57L/J m 389.2857 36.9102 461.9223 316.6491
DBA/2J f 207.6 39.8675 286.0565 129.1435
DBA/2J m 212.0 39.8675 290.4565 133.5435
FVB/NJ f 298.2857 36.9102 370.9223 225.6491
FVB/NJ m 319.25 28.1906 374.7271 263.7729
KK/HlJ f 481.8333 39.8675 560.2898 403.3769
KK/HlJ m 308.7143 36.9102 381.3509 236.0777
MRL/MpJ f 329.8571 36.9102 402.4937 257.2206
MRL/MpJ m 286.6875 34.5263 354.6328 218.7422
NOD.B10Sn-H2b/J f 440.6667 39.8675 519.1231 362.2102
NOD.B10Sn-H2b/J m 405.0 39.8675 483.4565 326.5435
NON/ShiLtJ f 327.8 43.6727 413.7448 241.8552
NON/ShiLtJ m 283.4286 36.9102 356.0652 210.792
NZO/HlLtJ f 278.8 30.8813 339.5721 218.0279
NZO/HlLtJ m 255.0 69.0526 390.8906 119.1094
NZW/LacJ f 297.5714 36.9102 370.208 224.9348
NZW/LacJ m 252.1667 39.8675 330.6231 173.7102
P/J f 270.1429 36.9102 342.7794 197.5063
P/J m 251.4 43.6727 337.3448 165.4552
PL/J f 457.25 34.5263 525.1953 389.3047
PL/J m 330.2222 32.5517 394.2817 266.1628
PWD/PhJ f 277.3333 39.8675 355.7898 198.8769
PWD/PhJ m 251.5714 36.9102 324.208 178.9348
RIIIS/J f 278.875 34.5263 346.8203 210.9297
RIIIS/J m 182.75 34.5263 250.6953 114.8047
SJL/J f 376.5714 36.9102 449.208 303.9348
SJL/J m 294.0 48.8275 390.0892 197.9108
SM/J f 233.6667 39.8675 312.1231 155.2102
SM/J m 263.0 30.8813 323.7721 202.2279
SWR/J f 377.8571 36.9102 450.4937 305.2206
SWR/J m 315.125 34.5263 383.0703 247.1797
WSB/EiJ f 264.875 34.5263 332.8203 196.9297
WSB/EiJ m 275.6667 32.5517 339.7261 211.6072


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
A/J both 305.3407 22.8907 350.388 260.2934
BALB/cByJ both 285.2589 25.2707 334.9898 235.5281
BTBR T+ Itpr3tf/J both 381.425 27.836 436.2043 326.6457
BUB/BnJ both 259.7833 29.5665 317.9682 201.5984
C57BL/10J both 421.0705 24.0987 468.4951 373.6459
C57BL/6J both 346.1429 26.0994 397.5047 294.781
C57BR/cdJ both 376.1875 24.4138 424.2321 328.1429
C57L/J both 363.6429 26.0994 415.0047 312.281
DBA/2J both 209.8 28.1906 265.2771 154.3229
FVB/NJ both 308.7679 23.2221 354.4674 263.0683
KK/HlJ both 395.2738 27.1651 448.7329 341.8147
MRL/MpJ both 308.2723 25.2707 358.0032 258.5414
NOD.B10Sn-H2b/J both 422.8333 28.1906 478.3104 367.3562
NON/ShiLtJ both 305.6143 28.5905 361.8783 249.3502
NZO/HlLtJ both 266.9 37.8217 341.3304 192.4696
NZW/LacJ both 274.869 27.1651 328.3281 221.41
P/J both 260.7714 28.5905 317.0355 204.5074
PL/J both 393.7361 23.7259 440.4271 347.0452
PWD/PhJ both 264.4524 27.1651 317.9115 210.9933
RIIIS/J both 230.8125 24.4138 278.8571 182.7679
SJL/J both 335.2857 30.6043 395.5128 275.0586
SM/J both 248.3333 25.2144 297.9536 198.7131
SWR/J both 346.4911 25.2707 396.2219 296.7602
WSB/EiJ both 270.2708 23.7259 316.9618 223.5799




  GWAS USING LINEAR MIXED MODELS