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Project measure / variable:   Peters4   LYMPH_M18

ID, description, units MPD:24315   LYMPH_M18   lymphocyte count (LYM; units per volume x 103)   [n/µL]  at age 18mo  
Data set, strains Peters4   inbred   30 strains     sex: both     age: 78wks
Procedure complete blood count
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  STRAIN COMPARISON PLOT
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Peters4 - lymphocyte count (LYM; units per volume x 103) at age 18mo



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested28 strains29 strains
Mean of the strain means4.96   n/µL 6.07   n/µL
Median of the strain means4.43   n/µL 5.47   n/µL
SD of the strain means± 2.42 ± 3.01
Coefficient of variation (CV)0.488 0.496
Min–max range of strain means1.74   –   11.4   n/µL 1.97   –   12.6   n/µL
Mean sample size per strain7.0   mice 7.7   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 90.6835 90.6835 16.6212 0.0001
strain 26 2378.1699 91.4681 16.765 < 0.0001
sex:strain 26 365.5084 14.058 2.5767 0.0001
Residuals 334 1822.2729 5.4559


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 5.04 1.58   8 0.558 0.313 3.02, 7.87 0.03
129S1/SvImJ m 2.86 1.25   7 0.473 0.438 1.27, 5.04 -1.07
A/J f 2.59 1.32   7 0.5 0.512 1.45, 5.38 -0.98
A/J m 3.3 1.02   15 0.264 0.309 1.53, 5.32 -0.92
BALB/cByJ f 4.45 2.25   8 0.796 0.506 0.84, 7.63 -0.21
BALB/cByJ m 5.49 2.17   7 0.821 0.396 1.7, 8.48 -0.19
BTBR T+ Itpr3tf/J f 4.74 1.52   8 0.537 0.321 2.84, 6.84 -0.09
BTBR T+ Itpr3tf/J m 7.34 2.79   6 1.14 0.379 2.6, 10.1 0.42
BUB/BnJ f 10.2 3.8   5 1.7 0.374 3.51, 12.5 2.17
BUB/BnJ m 12.6 3.83   6 1.56 0.304 7.52, 18.2 2.17
C3H/HeJ f 2.79 1.31   7 0.494 0.468 0.73, 4.11 -0.9
C3H/HeJ m 4.32 1.55   8 0.548 0.358 1.76, 6.93 -0.58
C57BL/10J f 9.09 6.83   7 2.58 0.752 2.1, 18.8 1.71
C57BL/10J m 11.0 3.33   13 0.923 0.301 5.17, 16.3 1.64
C57BL/6J f 7.12 2.52   7 0.954 0.355 3.77, 11.8 0.89
C57BL/6J m 11.5 1.31   7 0.494 0.114 9.82, 13.3 1.8
C57BLKS/J m 9.45 2.37   16 0.593 0.251 4.73, 12.8 1.12
C57BR/cdJ f 5.67 2.77   8 0.98 0.489 2.63, 11.3 0.29
C57BR/cdJ m 10.3 2.4   8 0.849 0.233 5.43, 13.5 1.41
C57L/J f 4.31 2.22   7 0.841 0.516 2.01, 7.91 -0.27
C57L/J m 8.59 3.74   7 1.42 0.436 1.86, 13.7 0.84
CAST/EiJ f 8.29 2.01   8 0.71 0.242 4.44, 11.6 1.38
CBA/J f 4.46 1.54   2   1.09 0.346 3.37, 5.55 -0.21
CBA/J m 2.79 1.17   5 0.524 0.42 0.98, 4.26 -1.09
DBA/2J f 5.65 2.8   6 1.14 0.495 2.1, 8.54 0.29
DBA/2J m 6.7 1.96   6 0.802 0.293 3.69, 8.8 0.21
FVB/NJ f 3.72 1.37   7 0.517 0.368 1.54, 5.71 -0.51
FVB/NJ m 2.85 1.19   12 0.344 0.417 0.62, 5.21 -1.07
KK/HlJ f 4.34 0.888   6 0.363 0.204 3.5, 5.87 -0.26
KK/HlJ m 6.35 2.0   7 0.755 0.314 4.27, 9.62 0.09
LP/J m 9.95 1.16   8 0.41 0.116 7.58, 11.1 1.29
MRL/MpJ f 1.74 0.383   7 0.145 0.221 1.27, 2.31 -1.33
MRL/MpJ m 2.97 0.997   8 0.353 0.335 1.81, 4.57 -1.03
NOD.B10Sn-H2b/J f 6.63 2.95   7 1.12 0.445 3.8, 11.9 0.69
NOD.B10Sn-H2b/J m 4.53 2.84   7 1.07 0.627 2.72, 10.9 -0.51
NON/ShiLtJ f 4.4 0.445   5 0.199 0.101 3.69, 4.76 -0.23
NON/ShiLtJ m 3.46 1.36   7 0.512 0.392 0.85, 5.28 -0.87
NZO/HlLtJ f 5.9 3.66   10 1.16 0.621 2.28, 14.4 0.39
NZO/HlLtJ m 6.57 0.495   2   0.35 0.0753 6.22, 6.92 0.17
NZW/LacJ f 11.4 6.26   7 2.37 0.552 4.16, 23.8 2.66
NZW/LacJ m 7.8 1.93   6 0.787 0.247 3.98, 9.21 0.58
P/J f 2.75 1.44   7 0.546 0.525 1.37, 5.41 -0.91
P/J m 4.77 1.58   5 0.706 0.331 2.45, 6.08 -0.43
PL/J f 2.21 0.756   8 0.267 0.342 0.75, 3.01 -1.14
PL/J m 1.97 0.711   8 0.251 0.362 0.64, 2.81 -1.36
PWD/PhJ f 3.34 0.692   6 0.282 0.207 2.55, 4.4 -0.67
PWD/PhJ m 4.77 1.27   7 0.48 0.266 3.57, 6.7 -0.43
RIIIS/J f 3.52 0.599   8 0.212 0.17 2.57, 4.15 -0.59
RIIIS/J m 5.26 0.653   8 0.231 0.124 4.79, 6.72 -0.27
SJL/J f 2.33 2.29   7 0.865 0.982 0.36, 6.42 -1.09
SJL/J m 2.16 0.566   4 0.283 0.262 1.79, 3.0 -1.3
SM/J f 3.12 0.965   6 0.394 0.309 1.95, 4.04 -0.76
SM/J m 5.47 2.11   9 0.703 0.386 4.26, 10.9 -0.2
SWR/J f 4.34 1.8   7 0.682 0.416 1.74, 7.44 -0.26
SWR/J m 6.56 2.24   8 0.793 0.342 2.46, 9.97 0.16
WSB/EiJ f 4.72 1.3   8 0.458 0.275 2.26, 6.62 -0.1
WSB/EiJ m 4.34 1.62   9 0.538 0.372 1.89, 6.32 -0.57


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 5.0363 0.8258 6.6607 3.4118
129S1/SvImJ m 2.8586 0.8828 4.5952 1.1219
A/J f 2.5857 0.8828 4.3224 0.8491
A/J m 3.3 0.6031 4.4863 2.1137
BALB/cByJ f 4.4538 0.8258 6.0782 2.8293
BALB/cByJ m 5.4929 0.8828 7.2295 3.7562
BTBR T+ Itpr3tf/J f 4.7363 0.8258 6.3607 3.1118
BTBR T+ Itpr3tf/J m 7.345 0.9536 9.2208 5.4692
BUB/BnJ f 10.182 1.0446 12.2368 8.1272
BUB/BnJ m 12.595 0.9536 14.4708 10.7192
C3H/HeJ f 2.7943 0.8828 4.5309 1.0576
C3H/HeJ m 4.3225 0.8258 5.947 2.698
C57BL/10J f 9.09 0.8828 10.8266 7.3534
C57BL/10J m 11.0492 0.6478 12.3236 9.7749
C57BL/6J f 7.1171 0.8828 8.8538 5.3805
C57BL/6J m 11.5171 0.8828 13.2538 9.7805
C57BR/cdJ f 5.6713 0.8258 7.2957 4.0468
C57BR/cdJ m 10.3188 0.8258 11.9432 8.6943
C57L/J f 4.3114 0.8828 6.0481 2.5748
C57L/J m 8.5886 0.8828 10.3252 6.8519
CBA/J f 4.46 1.6517 7.709 1.211
CBA/J m 2.786 1.0446 4.8408 0.7312
DBA/2J f 5.6533 0.9536 7.5291 3.7776
DBA/2J m 6.695 0.9536 8.5708 4.8192
FVB/NJ f 3.72 0.8828 5.4566 1.9834
FVB/NJ m 2.8533 0.6743 4.1797 1.527
KK/HlJ f 4.345 0.9536 6.2208 2.4692
KK/HlJ m 6.3543 0.8828 8.0909 4.6176
MRL/MpJ f 1.7357 0.8828 3.4724 0.0
MRL/MpJ m 2.9737 0.8258 4.5982 1.3493
NOD.B10Sn-H2b/J f 6.63 0.8828 8.3666 4.8934
NOD.B10Sn-H2b/J m 4.5257 0.8828 6.2624 2.7891
NON/ShiLtJ f 4.396 1.0446 6.4508 2.3412
NON/ShiLtJ m 3.46 0.8828 5.1966 1.7234
NZO/HlLtJ f 5.902 0.7386 7.355 4.449
NZO/HlLtJ m 6.57 1.6517 9.819 3.321
NZW/LacJ f 11.3543 0.8828 13.0909 9.6176
NZW/LacJ m 7.795 0.9536 9.6708 5.9192
P/J f 2.7514 0.8828 4.4881 1.0148
P/J m 4.774 1.0446 6.8288 2.7192
PL/J f 2.2137 0.8258 3.8382 0.5893
PL/J m 1.9662 0.8258 3.5907 0.3418
PWD/PhJ f 3.34 0.9536 5.2158 1.4642
PWD/PhJ m 4.77 0.8828 6.5066 3.0334
RIIIS/J f 3.5175 0.8258 5.142 1.893
RIIIS/J m 5.2575 0.8258 6.882 3.633
SJL/J f 2.3314 0.8828 4.0681 0.5948
SJL/J m 2.1625 1.1679 4.4599 0.0
SM/J f 3.1183 0.9536 4.9941 1.2426
SM/J m 5.4667 0.7786 6.9982 3.9351
SWR/J f 4.3357 0.8828 6.0724 2.5991
SWR/J m 6.5575 0.8258 8.182 4.933
WSB/EiJ f 4.7163 0.8258 6.3407 3.0918
WSB/EiJ m 4.3433 0.7786 5.8749 2.8118


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 3.9474 0.6044 5.1364 2.7584
A/J both 2.9429 0.5346 3.9944 1.8913
BALB/cByJ both 4.9733 0.6044 6.1623 3.7843
BTBR T+ Itpr3tf/J both 6.0406 0.6307 7.2813 4.7999
BUB/BnJ both 11.3885 0.7072 12.7796 9.9974
C3H/HeJ both 3.5584 0.6044 4.7474 2.3694
C57BL/10J both 10.0696 0.5475 11.1466 8.9926
C57BL/6J both 9.3171 0.6243 10.5451 8.0892
C57BR/cdJ both 7.995 0.5839 9.1437 6.8463
C57L/J both 6.45 0.6243 7.678 5.222
CBA/J both 3.623 0.9771 5.5451 1.7009
DBA/2J both 6.1742 0.6743 7.5005 4.8478
FVB/NJ both 3.2867 0.5554 4.3793 2.1941
KK/HlJ both 5.3496 0.6498 6.6278 4.0715
MRL/MpJ both 2.3547 0.6044 3.5437 1.1657
NOD.B10Sn-H2b/J both 5.5779 0.6243 6.8058 4.3499
NON/ShiLtJ both 3.928 0.6838 5.2732 2.5828
NZO/HlLtJ both 6.236 0.9046 8.0155 4.4565
NZW/LacJ both 9.5746 0.6498 10.8528 8.2965
P/J both 3.7627 0.6838 5.1079 2.4175
PL/J both 2.09 0.5839 3.2387 0.9413
PWD/PhJ both 4.055 0.6498 5.3331 2.7769
RIIIS/J both 4.3875 0.5839 5.5362 3.2388
SJL/J both 2.247 0.732 3.6869 0.807
SM/J both 4.2925 0.6155 5.5033 3.0817
SWR/J both 5.4466 0.6044 6.6356 4.2576
WSB/EiJ both 4.5298 0.5675 5.6461 3.4135




  GWAS USING LINEAR MIXED MODELS