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Project measure / variable:   Donahue2   quadricep_wt

ID, description, units MPD:17224   quadricep_wt   weight of isolated right quadriceps muscle   [g]  
Data set, strains Donahue2   inbred   10 strains     sex: both     age: 16wks
Procedure muscle weights
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  STRAIN COMPARISON PLOT
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Donahue2 - weight of isolated right quadriceps muscle



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested10 strains10 strains
Mean of the strain means0.165   g 0.225   g
Median of the strain means0.168   g 0.229   g
SD of the strain means± 0.0250 ± 0.0410
Coefficient of variation (CV)0.151 0.182
Min–max range of strain means0.116   –   0.210   g 0.126   –   0.278   g
Mean sample size per strain10.0   mice 11.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.1933 0.1933 181.6333 < 0.0001
strain 9 0.2055 0.0228 21.4626 < 0.0001
sex:strain 9 0.0224 0.0025 2.3436 0.0157
Residuals 192 0.2043 0.0011


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 0.169 0.0322   10 0.0102 0.19 0.0925, 0.204 0.15
129S1/SvImJ m 0.232 0.0606   15 0.0157 0.262 0.147, 0.318 0.17
BALB/cJ f 0.18 0.0167   10 0.00527 0.0927 0.152, 0.211 0.59
BALB/cJ m 0.264 0.0285   10 0.00901 0.108 0.214, 0.294 0.95
C3H/HeJ f 0.148 0.0276   9 0.00919 0.186 0.101, 0.185 -0.69
C3H/HeJ m 0.226 0.0506   11 0.0153 0.223 0.141, 0.281 0.03
C57BL/6J f 0.21 0.0406   10 0.0128 0.194 0.147, 0.256 1.79
C57BL/6J m 0.278 0.0505   12 0.0146 0.182 0.206, 0.361 1.3
C58/J f 0.159 0.0162   10 0.00513 0.102 0.138, 0.192 -0.25
C58/J m 0.205 0.0221   10 0.00699 0.108 0.171, 0.246 -0.49
FVB/NJ f 0.181 0.0205   11 0.00618 0.113 0.145, 0.225 0.63
FVB/NJ m 0.24 0.0176   9 0.00586 0.0732 0.215, 0.269 0.37
NZB/BlNJ f 0.175 0.0368   11 0.0111 0.211 0.0954, 0.228 0.39
NZB/BlNJ m 0.24 0.0173   13 0.0048 0.072 0.215, 0.269 0.37
PWK/PhJ f 0.116 0.0184   12 0.00531 0.158 0.0846, 0.143 -1.97
PWK/PhJ m 0.126 0.0165   11 0.00498 0.132 0.102, 0.154 -2.41
SJL/J f 0.167 0.0356   8 0.0126 0.213 0.107, 0.222 0.07
SJL/J m 0.216 0.0247   11 0.00746 0.115 0.185, 0.256 -0.22
SWR/J f 0.148 0.018   9 0.00599 0.121 0.128, 0.177 -0.69
SWR/J m 0.222 0.0222   10 0.00703 0.1 0.189, 0.261 -0.07


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 0.1695 0.0103 0.1898 0.1491
129S1/SvImJ m 0.2317 0.0084 0.2483 0.2151
BALB/cJ f 0.1797 0.0103 0.2 0.1594
BALB/cJ m 0.2639 0.0103 0.2842 0.2436
C3H/HeJ f 0.1481 0.0109 0.1696 0.1267
C3H/HeJ m 0.2264 0.0098 0.2458 0.207
C57BL/6J f 0.2096 0.0103 0.2299 0.1893
C57BL/6J m 0.2777 0.0094 0.2962 0.2591
C58/J f 0.1594 0.0103 0.1797 0.1391
C58/J m 0.2051 0.0103 0.2254 0.1848
FVB/NJ f 0.1812 0.0098 0.2006 0.1618
FVB/NJ m 0.2403 0.0109 0.2618 0.2189
NZB/BlNJ f 0.1749 0.0098 0.1943 0.1555
NZB/BlNJ m 0.2405 0.009 0.2583 0.2226
PWK/PhJ f 0.1164 0.0094 0.135 0.0979
PWK/PhJ m 0.1255 0.0098 0.1449 0.1061
SJL/J f 0.1669 0.0115 0.1896 0.1441
SJL/J m 0.2158 0.0098 0.2352 0.1964
SWR/J f 0.1484 0.0109 0.1699 0.127
SWR/J m 0.2221 0.0103 0.2424 0.2018


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 0.2006 0.0067 0.2137 0.1875
BALB/cJ both 0.2218 0.0073 0.2362 0.2074
C3H/HeJ both 0.1872 0.0073 0.2017 0.1728
C57BL/6J both 0.2436 0.007 0.2574 0.2299
C58/J both 0.1823 0.0073 0.1966 0.1679
FVB/NJ both 0.2108 0.0073 0.2252 0.1963
NZB/BlNJ both 0.2077 0.0067 0.2208 0.1945
PWK/PhJ both 0.121 0.0068 0.1344 0.1076
SJL/J both 0.1913 0.0076 0.2063 0.1764
SWR/J both 0.1853 0.0075 0.2001 0.1705




  GWAS USING LINEAR MIXED MODELS