Project measure / variable:   Donahue2   femur_shaft_BMD

ID, description, units MPD:17204   femur_shaft_BMD   cross sectional volumetric bone mineral density (vBMD), right femur mid-diaphysis   [g/cm3]  
Data set, strains Donahue2   inbred   10 strains     sex: both     age: 16wks
Procedure DXA
Ontology mappings

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  STRAIN COMPARISON PLOT
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Donahue2 - cross sectional volumetric bone mineral density (vBMD), right femur mid-diaphysis

C3H/HeJBALB/cJNZB/BlNJ129S1/SvImJSJL/JPWK/PhJSWR/JC58/JFVB/NJC57BL/6J g/cm3 0.550.600.650.700.750.800.850.900.951.001.05femalemale


  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested10 strains10 strains
Mean of the strain means0.750   g/cm3 0.743   g/cm3
Median of the strain means0.735   g/cm3 0.708   g/cm3
SD of the strain means± 0.104 ± 0.105
Coefficient of variation (CV)0.138 0.142
Min–max range of strain means0.632   –   1.00   g/cm3 0.620   –   0.966   g/cm3
Mean sample size per strain10.0   mice 10.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.0003 0.0003 0.1569 0.6925
strain 9 1.9187 0.2132 128.4736 < 0.0001
sex:strain 9 0.0621 0.0069 4.1582 0.0001
Residuals 191 0.317 0.0017


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page: 1 - 10 / 20 (20)
Strain
Sex
Mean
SD
N mice
SEM
CV
Min, Max
Z score
129S1/SvImJ f 0.766 0.023   10 0.00727 0.03 0.738, 0.805 0.15
129S1/SvImJ m 0.8 0.063   15 0.0163 0.0787 0.719, 0.982 0.54
BALB/cJ f 0.807 0.019   10 0.00602 0.0236 0.772, 0.832 0.55
BALB/cJ m 0.829 0.0304   10 0.00963 0.0367 0.77, 0.871 0.81
C3H/HeJ f 1.0 0.0258   9 0.00862 0.0257 0.966, 1.04 2.41
C3H/HeJ m 0.966 0.0288   10 0.0091 0.0298 0.921, 1.0 2.11
C57BL/6J f 0.632 0.0153   10 0.00483 0.0242 0.607, 0.661 -1.14
C57BL/6J m 0.62 0.0345   12 0.00995 0.0557 0.542, 0.669 -1.17
C58/J f 0.688 0.0366   10 0.0116 0.0531 0.617, 0.75 -0.6
C58/J m 0.674 0.0167   10 0.00528 0.0248 0.643, 0.697 -0.66
FVB/NJ f 0.692 0.032   11 0.00963 0.0462 0.651, 0.745 -0.56
FVB/NJ m 0.64 0.0191   9 0.00636 0.0298 0.617, 0.682 -0.98
NZB/BlNJ f 0.782 0.0219   11 0.00661 0.028 0.756, 0.819 0.31
NZB/BlNJ m 0.803 0.085   13 0.0236 0.106 0.727, 1.06 0.56
PWK/PhJ f 0.714 0.0288   12 0.00831 0.0403 0.664, 0.769 -0.35
PWK/PhJ m 0.711 0.0415   11 0.0125 0.0583 0.639, 0.767 -0.31
SJL/J f 0.756 0.0887   8 0.0314 0.117 0.682, 0.955 0.06
SJL/J m 0.688 0.0275   11 0.00829 0.04 0.641, 0.732 -0.53
SWR/J f 0.664 0.0166   9 0.00554 0.0251 0.648, 0.698 -0.83
SWR/J m 0.704 0.0274   10 0.00867 0.0389 0.659, 0.744 -0.37


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 0.7662 0.0129 0.7916 0.7408
129S1/SvImJ m 0.8002 0.0105 0.8209 0.7795
BALB/cJ f 0.8068 0.0129 0.8322 0.7814
BALB/cJ m 0.829 0.0129 0.8544 0.8036
C3H/HeJ f 1.0046 0.0136 1.0313 0.9778
C3H/HeJ m 0.9663 0.0129 0.9917 0.9409
C57BL/6J f 0.6318 0.0129 0.6572 0.6064
C57BL/6J m 0.6195 0.0118 0.6427 0.5963
C58/J f 0.6882 0.0129 0.7136 0.6628
C58/J m 0.6735 0.0129 0.6989 0.6481
FVB/NJ f 0.6923 0.0123 0.7165 0.668
FVB/NJ m 0.6396 0.0136 0.6663 0.6128
NZB/BlNJ f 0.7819 0.0123 0.8061 0.7577
NZB/BlNJ m 0.8028 0.0113 0.8251 0.7805
PWK/PhJ f 0.7139 0.0118 0.7371 0.6907
PWK/PhJ m 0.7114 0.0123 0.7356 0.6871
SJL/J f 0.7556 0.0144 0.784 0.7272
SJL/J m 0.6879 0.0123 0.7121 0.6637
SWR/J f 0.6637 0.0136 0.6905 0.6369
SWR/J m 0.7041 0.0129 0.7295 0.6787


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 0.7832 0.0083 0.7996 0.7668
BALB/cJ both 0.8179 0.0091 0.8359 0.7999
C3H/HeJ both 0.9854 0.0094 1.0039 0.967
C57BL/6J both 0.6256 0.0087 0.6429 0.6084
C58/J both 0.6809 0.0091 0.6988 0.6629
FVB/NJ both 0.6659 0.0092 0.684 0.6479
NZB/BlNJ both 0.7923 0.0083 0.8088 0.7759
PWK/PhJ both 0.7126 0.0085 0.7294 0.6959
SJL/J both 0.7218 0.0095 0.7404 0.7031
SWR/J both 0.6839 0.0094 0.7023 0.6654




  GWAS USING LINEAR MIXED MODELS

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