Project measure / variable:   Crabbe1   bal15_doseB

ID, description, units MPD:15412   bal15_doseB   missteps crossing 15.8mm wide balance beam   [n]  dose 1.2 g/kg i.p.  
ethanol study
Data set, strains Crabbe1   inbred   8 strains     sex: both     age: 8-16wks
Procedure balance beam
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  STRAIN COMPARISON PLOT
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Crabbe1 - missteps crossing 15.8mm wide balance beam dose 1.2 g/kg i.p.



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means1.74   n 3.46   n
Median of the strain means1.62   n 3.38   n
SD of the strain means± 0.984 ± 1.57
Coefficient of variation (CV)0.564 0.455
Min–max range of strain means0.808   –   3.80   n 0.903   –   5.82   n
Mean sample size per strain5.8   mice 5.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 35.833 35.833 7.3275 0.0085
strain 7 80.3178 11.474 2.3463 0.0327
sex:strain 7 33.8512 4.8359 0.9889 0.4465
Residuals 70 342.3123 4.8902


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 1.89 1.92   3 1.11 1.02 0.15
129S1/SvImJ m 5.82 5.55   3 3.21 0.954 0.83, 11.8 1.5
A/J f 1.0 1.54   5 0.689 1.54 -0.76
A/J m 4.83 4.16   3 2.4 0.861 1.5, 9.5 0.87
BALB/cByJ f 2.14 2.19   7 0.826 1.02 0.4
BALB/cByJ m 2.36 2.03   6 0.83 0.862 -0.7
BTBR T+ Itpr3tf/J f 2.05 2.07   6 0.845 1.01 0.31
BTBR T+ Itpr3tf/J m 3.58 3.4   4 1.7 0.951 0.33, 8.33 0.08
C3H/HeJ f 3.8 3.35   5 1.5 0.881 2.09
C3H/HeJ m 4.5 1.73   3 1.0 0.385 2.5, 5.5 0.66
C57BL/6J f 0.808 0.847   6 0.346 1.05 -0.95
C57BL/6J m 2.5 1.67   8 0.591 0.668 -0.61
DBA/2J f 1.36 1.31   7 0.497 0.968 -0.39
DBA/2J m 3.17 2.07   6 0.843 0.652 0.5, 6.5 -0.18
FVB/NJ f 0.903 1.36   7 0.512 1.5 -0.85
FVB/NJ m 0.903 1.08   7 0.409 1.2 -1.63


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 1.8867 1.2767 4.433 0.0
129S1/SvImJ m 5.82 1.2767 8.3664 3.2736
A/J f 1.0 0.989 2.9724 0.0
A/J m 4.8333 1.2767 7.3797 2.287
BALB/cByJ f 2.14 0.8358 3.807 0.473
BALB/cByJ m 2.3583 0.9028 4.1589 0.5578
BTBR T+ Itpr3tf/J f 2.0533 0.9028 3.8539 0.2528
BTBR T+ Itpr3tf/J m 3.58 1.1057 5.7852 1.3748
C3H/HeJ f 3.8 0.989 5.7724 1.8276
C3H/HeJ m 4.5 1.2767 7.0464 1.9536
C57BL/6J f 0.8083 0.9028 2.6089 0.0
C57BL/6J m 2.5025 0.7818 4.0618 0.9432
DBA/2J f 1.3571 0.8358 3.0241 0.0
DBA/2J m 3.1667 0.9028 4.9672 1.3661
FVB/NJ f 0.9029 0.8358 2.5698 0.0
FVB/NJ m 0.9029 0.8358 2.5698 0.0


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 3.8533 0.9028 5.6539 2.0528
A/J both 2.9167 0.8075 4.5271 1.3062
BALB/cByJ both 2.2492 0.6151 3.476 1.0223
BTBR T+ Itpr3tf/J both 2.8167 0.7137 4.2401 1.3932
C3H/HeJ both 4.15 0.8075 5.7605 2.5395
C57BL/6J both 1.6554 0.5971 2.8464 0.4645
DBA/2J both 2.2619 0.6151 3.4888 1.035
FVB/NJ both 0.9029 0.591 2.0816 0.0




  GWAS USING LINEAR MIXED MODELS