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Project measure / variable:   Justice2   HCT


  STRAIN COMPARISON PLOT
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Justice2 - hematocrit (HCT)



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested16 strains16 strains
Mean of the strain means44.5   % 44.0   %
Median of the strain means44.3   % 43.1   %
SD of the strain means± 1.85 ± 1.83
Coefficient of variation (CV)0.0416 0.0416
Min–max range of strain means41.7   –   48.8   % 41.9   –   48.5   %
Mean sample size per strain12.6   mice 12.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 23.5604 23.5604 11.5358 0.0008
strain 15 1261.9562 84.1304 41.1925 < 0.0001
sex:strain 15 75.7394 5.0493 2.4723 0.0018
Residuals 365 745.4662 2.0424


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 48.8 0.791   15 0.204 0.0162 47.2, 49.9 2.3
129S1/SvImJ m 48.5 1.24   15 0.32 0.0255 45.6, 51.4 2.44
129S6/SvEvTac f 46.9 1.34   10 0.422 0.0285 44.2, 48.4 1.27
129S6/SvEvTac m 45.7 3.41   10 1.08 0.0746 37.8, 49.9 0.91
A/J f 44.2 1.25   10 0.394 0.0282 42.2, 45.6 -0.18
A/J m 42.9 1.6   8 0.565 0.0372 41.1, 45.6 -0.62
BALB/cByJ f 46.0 1.33   15 0.343 0.0289 43.0, 48.1 0.79
BALB/cByJ m 44.4 1.5   15 0.388 0.0339 40.3, 46.8 0.2
BALB/cJ f 44.1 0.796   10 0.252 0.018 42.7, 45.2 -0.24
BALB/cJ m 43.0 1.43   9 0.476 0.0332 41.5, 45.7 -0.56
BTBR T+ Itpr3tf/J f 43.2 0.794   10 0.251 0.0184 41.8, 44.1 -0.72
BTBR T+ Itpr3tf/J m 42.5 0.959   10 0.303 0.0226 40.8, 44.0 -0.84
C3HeB/FeJ f 43.0 1.32   15 0.342 0.0308 39.4, 45.6 -0.83
C3HeB/FeJ m 43.0 1.07   15 0.276 0.0248 41.0, 44.2 -0.56
C3H/HeJ f 42.8 1.25   10 0.394 0.0291 40.8, 44.3 -0.94
C3H/HeJ m 42.6 1.33   10 0.421 0.0312 40.3, 44.4 -0.78
C57BL/10J f 44.4 0.974   13 0.27 0.0219 42.3, 46.2 -0.07
C57BL/10J m 43.3 1.26   15 0.325 0.029 41.3, 45.4 -0.4
C57BL/6J f 46.2 1.2   15 0.311 0.0261 44.0, 47.7 0.9
C57BL/6J m 45.4 1.69   14 0.453 0.0373 41.4, 48.4 0.75
CAST/EiJ f 45.3 1.35   9 0.451 0.0298 43.4, 47.3 0.41
CAST/EiJ m 45.8 1.46   9 0.488 0.0319 43.9, 48.3 0.97
CBA/CaJ f 45.3 1.68   14 0.449 0.0371 40.7, 47.1 0.41
CBA/CaJ m 45.2 1.39   14 0.372 0.0308 43.1, 46.9 0.64
CBA/J f 42.1 1.4   10 0.444 0.0333 39.7, 44.4 -1.31
CBA/J m 42.1 0.809   9 0.27 0.0192 40.6, 43.3 -1.05
DBA/2J f 44.0 1.06   15 0.275 0.0242 41.8, 46.5 -0.29
DBA/2J m 45.6 2.29   14 0.612 0.0503 43.1, 51.8 0.86
FVB/NJ f 41.7 1.39   15 0.359 0.0334 39.2, 43.8 -1.53
FVB/NJ m 41.9 1.02   15 0.264 0.0244 39.9, 43.5 -1.16
SJL/J f 44.6 1.59   15 0.411 0.0357 41.2, 46.4 0.03
SJL/J m 42.6 1.54   14 0.412 0.0362 40.2, 44.8 -0.78


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 48.8 0.369 49.5256 48.0744
129S1/SvImJ m 48.54 0.369 49.2656 47.8144
129S6/SvEvTac f 46.89 0.4519 47.7787 46.0013
129S6/SvEvTac m 45.67 0.4519 46.5587 44.7813
A/J f 44.2 0.4519 45.0887 43.3113
A/J m 42.925 0.5053 43.9186 41.9314
BALB/cByJ f 46.0333 0.369 46.759 45.3077
BALB/cByJ m 44.4133 0.369 45.139 43.6877
BALB/cJ f 44.14 0.4519 45.0287 43.2513
BALB/cJ m 43.0333 0.4764 43.9701 42.0966
BTBR T+ Itpr3tf/J f 43.21 0.4519 44.0987 42.3213
BTBR T+ Itpr3tf/J m 42.49 0.4519 43.3787 41.6013
C3HeB/FeJ f 43.0 0.369 43.7256 42.2744
C3HeB/FeJ m 43.0267 0.369 43.7523 42.301
C3H/HeJ f 42.83 0.4519 43.7187 41.9413
C3H/HeJ m 42.58 0.4519 43.4687 41.6913
C57BL/10J f 44.4385 0.3964 45.2179 43.659
C57BL/10J m 43.3467 0.369 44.0723 42.621
C57BL/6J f 46.1733 0.369 46.899 45.4477
C57BL/6J m 45.4214 0.3819 46.1725 44.6703
CAST/EiJ f 45.3 0.4764 46.2368 44.3632
CAST/EiJ m 45.8444 0.4764 46.7812 44.9077
CBA/CaJ f 45.3071 0.3819 46.0582 44.556
CBA/CaJ m 45.1643 0.3819 45.9154 44.4132
CBA/J f 42.12 0.4519 43.0087 41.2313
CBA/J m 42.0556 0.4764 42.9923 41.1188
DBA/2J f 44.04 0.369 44.7656 43.3144
DBA/2J m 45.55 0.3819 46.3011 44.7989
FVB/NJ f 41.72 0.369 42.4456 40.9944
FVB/NJ m 41.8533 0.369 42.579 41.1277
SJL/J f 44.56 0.369 45.2856 43.8344
SJL/J m 42.65 0.3819 43.4011 41.8989


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 48.67 0.2609 49.1831 48.1569
129S6/SvEvTac both 46.28 0.3196 46.9084 45.6516
A/J both 43.5625 0.3389 44.229 42.896
BALB/cByJ both 45.2233 0.2609 45.7364 44.7102
BALB/cJ both 43.5867 0.3283 44.2323 42.941
BTBR T+ Itpr3tf/J both 42.85 0.3196 43.4784 42.2216
C3HeB/FeJ both 43.0133 0.2609 43.5264 42.5002
C3H/HeJ both 42.705 0.3196 43.3334 42.0766
C57BL/10J both 43.8926 0.2708 44.425 43.3601
C57BL/6J both 45.7974 0.2655 46.3196 45.2752
CAST/EiJ both 45.5722 0.3368 46.2346 44.9098
CBA/CaJ both 45.2357 0.2701 45.7668 44.7046
CBA/J both 42.0878 0.3283 42.7334 41.4421
DBA/2J both 44.795 0.2655 45.3172 44.2728
FVB/NJ both 41.7867 0.2609 42.2998 41.2736
SJL/J both 43.605 0.2655 44.1272 43.0828




  GWAS USING LINEAR MIXED MODELS