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Project measure / variable:   Project1202   CFC.PS4_3_5XFAD_Chow

ID, description, units MPD:130453   CFC.PS4_3_5XFAD_Chow   CFC.PS4    3 5XFAD Chow  
Data set, strains Project1202   F1 AD-BXD   43 strains     sex: both
Procedure None
Ontology mappings


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  STRAIN COMPARISON PLOT
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Project1202 - CFC.PS4 3 5XFAD Chow



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested41 strains33 strains
Mean of the strain means50.38   None 49.522   None
Median of the strain means51.0   None 48.667   None
SD of the strain means± 12.906 ± 11.363
Coefficient of variation (CV)0.2561 0.2294
Min–max range of strain means26.888   –   82.0   None 25.6   –   72.22   None
Mean sample size per strain6.1   mice 6.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 19.5133 19.5133 0.0497 0.8238
strain 30 32253.2663 1075.1089 2.7358 < 0.0001
sex:strain 30 18232.7131 607.7571 1.5465 0.0359
Residuals 372 146188.4051 392.9796


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
(B6.5XFAD x BXD100)F1-ADtg f 41.0 0.46669   2   0.33 0.0114 40.67, 41.33 -0.73
(B6.5XFAD x BXD113)F1 f 57.67 8.1832   6 3.3408 0.1419 50.67, 72.0 0.56
(B6.5XFAD x BXD113)F1 m 57.22 18.702   6 7.635 0.3268 36.0, 86.0 0.68
(B6.5XFAD x BXD124)F1 f 31.733 18.041   10 5.7051 0.5685 12.0, 65.33 -1.45
(B6.5XFAD x BXD124)F1 m 72.22 23.622   6 9.6436 0.3271 29.33, 92.0 2.0
(B6.5XFAD x BXD125)F1 f 39.186 26.555   9 8.8517 0.6777 -0.87
(B6.5XFAD x BXD125)F1 m 48.222 23.475   6 9.5836 0.4868 7.33, 79.33 -0.11
(B6.5XFAD x BXD12)F1 f 48.89 22.558   9 7.5192 0.4614 13.33, 84.67 -0.12
(B6.5XFAD x BXD12)F1 m 45.667 30.78   6 12.566 0.674 9.33, 84.67 -0.34
(B6.5XFAD x BXD14)F1-ADtg f 43.62 23.662   7 8.9435 0.5425 20.67, 90.67 -0.52
(B6.5XFAD x BXD14)F1-ADtg m 51.63 26.313   9 8.7709 0.5096 3.33, 86.67 0.19
(B6.5XFAD x BXD152)F1 f 65.24 16.863   7 6.3737 0.2585 38.0, 82.67 1.15
(B6.5XFAD x BXD152)F1 m 61.55 17.99   5 8.0452 0.2923 34.69, 84.0 1.06
(B6.5XFAD x BXD154)F1 f 40.477 18.35   7 6.9356 0.4533 17.33, 74.0 -0.77
(B6.5XFAD x BXD154)F1 m 50.5 25.968   8 9.1812 0.5142 18.0, 92.0 0.09
(B6.5XFAD x BXD161)F1 f 33.916 20.398   8 7.2116 0.6014 15.33, 66.67 -1.28
(B6.5XFAD x BXD161)F1 m 49.523 14.118   7 5.3362 0.2851 35.33, 69.33 0.0
(B6.5XFAD x BXD169)F1 f 56.25 21.656   8 7.6564 0.385 31.33, 92.67 0.45
(B6.5XFAD x BXD169)F1 m 36.666 17.197   5 7.6909 0.469 18.0, 61.33 -1.13
(B6.5XFAD x BXD16)F1-ADtg f 68.83 16.094   8 5.6902 0.2338 44.0, 92.0 1.43
(B6.5XFAD x BXD16)F1-ADtg m 62.67 23.277   5 10.41 0.3714 33.33, 83.33 1.16
(B6.5XFAD x BXD172)F1 f 78.67 0.0   1   0.0 0.0 78.67, 78.67 2.19
(B6.5XFAD x BXD19)F1 f 51.33 11.18   6 4.5644 0.2178 35.33, 63.33 0.07
(B6.5XFAD x BXD19)F1 m 48.266 29.131   5 13.028 0.6035 2.0, 72.0 -0.11
(B6.5XFAD x BXD22)F1-ADtg f 33.777 19.048   3 10.997 0.5639 14.0, 52.0 -1.29
(B6.5XFAD x BXD28)F1 f 47.385 21.499   13 5.9629 0.4537 2.67, 74.0 -0.23
(B6.5XFAD x BXD28)F1 m 45.047 19.411   7 7.3368 0.4309 12.67, 61.33 -0.39
(B6.5XFAD x BXD31)F1 f 82.0 0.0   1   0.0 0.0 82.0, 82.0 2.45
(B6.5XFAD x BXD33)F1 f 52.0 28.284   2   20.0 0.5439 32.0, 72.0 0.13
(B6.5XFAD x BXD34)F1-ADtg f 38.132 15.036   5 6.7241 0.3943 25.33, 63.33 -0.95
(B6.5XFAD x BXD38)F1 f 44.0 15.65   6 6.3892 0.3557 28.67, 64.0 -0.49
(B6.5XFAD x BXD38)F1 m 48.667 22.275   7 8.4191 0.4577 22.0, 82.67 -0.08
(B6.5XFAD x BXD39)F1 f 54.93 17.17   5 7.6787 0.3126 40.0, 84.0 0.35
(B6.5XFAD x BXD39)F1 m 63.22 6.9973   6 2.8567 0.1107 54.0, 74.0 1.21
(B6.5XFAD x BXD48a)F1 m 59.0 19.332   2   13.67 0.3277 45.33, 72.67 0.83
(B6.5XFAD x BXD49)F1 f 65.34 21.197   3 12.238 0.3244 42.67, 84.67 1.16
(B6.5XFAD x BXD50)F1 f 42.37 18.711   9 6.237 0.4416 14.0, 69.33 -0.62
(B6.5XFAD x BXD50)F1 m 44.477 24.681   7 9.3287 0.5549 14.67, 74.0 -0.44
(B6.5XFAD x BXD55)F1-ADtg f 26.888 24.509   6 10.006 0.9115 6.0, 72.67 -1.82
(B6.5XFAD x BXD55)F1-ADtg m 25.868 18.889   5 8.4476 0.7302 5.33, 52.67 -2.08
(B6.5XFAD x BXD60)F1-ADtg f 54.44 8.5994   3 4.9649 0.158 47.33, 64.0 0.31
(B6.5XFAD x BXD60)F1-ADtg m 69.67 21.275   6 8.6856 0.3054 32.67, 89.33 1.77
(B6.5XFAD x BXD61)F1-ADtg f 58.0 14.114   9 4.7047 0.2433 28.67, 70.67 0.59
(B6.5XFAD x BXD61)F1-ADtg m 40.297 22.73   9 7.5767 0.5641 2.67, 66.0 -0.81
(B6.5XFAD x BXD62)F1-ADtg f 66.15 12.83   9 4.2767 0.194 42.67, 86.0 1.22
(B6.5XFAD x BXD62)F1-ADtg m 44.333 23.571   6 9.6227 0.5317 26.0, 75.33 -0.46
(B6.5XFAD x BXD65a)F1 f 42.668 25.759   4 12.88 0.6037 16.0, 72.67 -0.6
(B6.5XFAD x BXD65)F1-ADtg f 54.0 11.857   6 4.8406 0.2196 32.67, 68.0 0.28
(B6.5XFAD x BXD65)F1-ADtg m 51.6 27.778   5 12.423 0.5383 6.67, 82.0 0.18
(B6.5XFAD x BXD66)F1-ADtg f 58.13 12.388   5 5.5402 0.2131 37.33, 70.67 0.6
(B6.5XFAD x BXD66)F1-ADtg m 49.832 30.485   4 15.243 0.6118 15.33, 81.33 0.03
(B6.5XFAD x BXD68)F1-ADtg f 42.381 21.989   7 8.3111 0.5188 16.67, 77.33 -0.62
(B6.5XFAD x BXD68)F1-ADtg m 43.334 20.03   5 8.9577 0.4622 22.0, 66.67 -0.54
(B6.5XFAD x BXD70)F1-ADtg f 27.33 5.6569   2   4.0 0.207 23.33, 31.33 -1.79
(B6.5XFAD x BXD73)F1 f 40.445 14.063   6 5.7414 0.3477 28.67, 66.0 -0.77
(B6.5XFAD x BXD73)F1 m 34.333 12.086   10 3.822 0.352 11.33, 53.33 -1.34
(B6.5XFAD x BXD74)F1 f 58.78 15.581   6 6.3609 0.2651 31.33, 73.33 0.65
(B6.5XFAD x BXD74)F1 m 48.223 16.27   6 6.6421 0.3374 32.0, 70.67 -0.11
(B6.5XFAD x BXD75)F1-ADtg f 38.416 18.499   8 6.5405 0.4815 14.67, 70.0 -0.93
(B6.5XFAD x BXD75)F1-ADtg m 25.6 16.351   10 5.1707 0.6387 3.33, 60.0 -2.11
(B6.5XFAD x BXD77)F1-ADtg f 54.09 20.894   7 7.897 0.3862 17.33, 76.0 0.29
(B6.5XFAD x BXD77)F1-ADtg m 44.4 17.797   10 5.6279 0.4008 16.67, 68.0 -0.45
(B6.5XFAD x BXD78)F1 f 60.66 9.4257   2   6.665 0.1554 54.0, 67.33 0.8
(B6.5XFAD x BXD83)F1 f 49.6 16.363   5 7.3177 0.3299 32.0, 70.67 -0.06
(B6.5XFAD x BXD83)F1 m 58.4 24.796   5 11.089 0.4246 31.33, 94.0 0.78
(B6.5XFAD x BXD87)F1-ADtg f 67.66 19.867   7 7.509 0.2936 40.27, 99.33 1.34
(B6.5XFAD x BXD87)F1-ADtg m 46.953 24.532   7 9.2722 0.5225 6.0, 72.67 -0.23
(B6.5XFAD x BXD99)F1-ADtg f 56.61 11.552   11 3.4831 0.2041 38.67, 76.67 0.48
(B6.5XFAD x BXD99)F1-ADtg m 56.89 23.738   6 9.6911 0.4173 15.33, 79.33 0.65
(B6.5XFAD x D2)F1-ADtg f 41.75 20.453   8 7.2313 0.4899 20.0, 68.0 -0.67
(B6.5XFAD x D2)F1-ADtg m 62.4 20.974   5 9.3798 0.3361 34.0, 83.33 1.13
(B6 x DBA/2J-Gpnmb+/SjJ)F1 m 29.557 10.375   3 5.99 0.351 18.67, 39.33 -1.76
C57BL/6J f 51.0 15.103   6 6.1659 0.2961 25.33, 66.67 0.05
C57BL/6J m 58.0 16.111   13 4.4684 0.2778 32.0, 86.0 0.75


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ 1 26.8883333333 8.0929968038 42.8020906972 10.9745759695
129S1/SvImJ 2 25.868 8.8654338146 43.3006477657 8.4353522343
A/J 1 54.4433333333 11.4452258402 76.9487848256 31.937881841
A/J 2 69.6666666667 8.0929968038 85.5804240305 53.7529093028
AKR/J 1 57.6683333333 8.0929968038 73.5820906972 41.7545759695
AKR/J 2 57.2216666667 8.0929968038 73.1354240305 41.3079093028
ALR/LtJ 1 40.4771428571 7.4926591084 55.2104192875 25.7438664268
ALR/LtJ 2 50.50125 7.0087408249 64.2829681468 36.7195318532
ALS/LtJ 1 33.91625 7.0087408249 47.6979681468 20.1345318532
ALS/LtJ 2 49.5228571429 7.4926591084 64.2561335732 34.7895807125
BALB/cJ 1 58.0011111111 6.6079042198 70.9946395884 45.0075826338
BALB/cJ 2 40.2966666667 6.6079042198 53.290195144 27.3031381894
BPH/2J 1 56.25 7.0087408249 70.0317181468 42.4682818532
BPH/2J 2 36.666 8.8654338146 54.0986477657 19.2333522343
BPL/1J 1 42.37 6.6079042198 55.3635284773 29.3764715227
BPL/1J 2 44.4771428571 7.4926591084 59.2104192875 29.7438664268
BPN/3J 1 54.932 8.8654338146 72.3646477657 37.4993522343
BPN/3J 2 63.2216666667 8.0929968038 79.1354240305 47.3079093028
BTBR T+ Itpr3tf/J 1 43.62 7.4926591084 58.3532764304 28.8867235696
BTBR T+ Itpr3tf/J 2 51.63 6.6079042198 64.6235284773 38.6364715227
BUB/BnJ 1 51.3316666667 8.0929968038 67.2454240305 35.4179093028
BUB/BnJ 2 48.266 8.8654338146 65.6986477657 30.8333522343
C3H/HeJ 1 66.1488888889 6.6079042198 79.1424173662 53.1553604116
C3H/HeJ 2 44.3333333333 8.0929968038 60.2470906972 28.4195759695
C57BL/6J 1 54.0 8.0929968038 69.9137573639 38.0862426361
C57BL/6J 2 51.6 8.8654338146 69.0326477657 34.1673522343
C58/J 1 40.445 8.0929968038 56.3587573639 24.5312426361
C58/J 2 34.333 6.2688083684 46.6597434492 22.0062565508
CAST/EiJ 1 68.83375 7.0087408249 82.6154681468 55.0520318532
CAST/EiJ 2 62.666 8.8654338146 80.0986477657 45.2333522343
CBA/J 1 48.89 6.6079042198 61.8835284773 35.8964715227
CBA/J 2 45.6666666667 8.0929968038 61.5804240305 29.7529093028
CE/J 1 47.3853846154 5.498108651 58.1966538094 36.5741154214
CE/J 2 45.0471428571 7.4926591084 59.7804192875 30.3138664268
DBA/2J 1 58.132 8.8654338146 75.5646477657 40.6993522343
DBA/2J 2 49.8325 9.9118563297 69.322792716 30.342207284
FVB/NJ 1 42.3814285714 7.4926591084 57.1147050018 27.6481521411
FVB/NJ 2 43.334 8.8654338146 60.7666477657 25.9013522343
I/LnJ 1 49.6 8.8654338146 67.0326477657 32.1673522343
I/LnJ 2 58.398 8.8654338146 75.8306477657 40.9653522343
KK/HlJ 1 39.1855555556 6.6079042198 52.1790840329 26.1920270782
KK/HlJ 2 48.2216666667 8.0929968038 64.1354240305 32.3079093028
LP/J 1 38.41625 7.0087408249 52.1979681468 24.6345318532
LP/J 2 25.6 6.2688083684 37.9267434492 13.2732565508
MA/MyJ 1 65.2385714286 7.4926591084 79.9718478589 50.5052949982
MA/MyJ 2 61.552 8.8654338146 78.9846477657 44.1193522343
NOD/ShiLtJ 1 56.6063636364 5.9770742585 68.3594523624 44.8532749104
NOD/ShiLtJ 2 56.8883333333 8.0929968038 72.8020906972 40.9745759695
NZB/BlNJ 1 54.0942857143 7.4926591084 68.8275621447 39.3610092839
NZB/BlNJ 2 44.4 6.2688083684 56.7267434492 32.0732565508
PL/J 1 41.75 7.0087408249 55.5317181468 27.9682818532
PL/J 2 62.4 8.8654338146 79.8326477657 44.9673522343
RIIIS/J 1 44.0 8.0929968038 59.9137573639 28.0862426361
RIIIS/J 2 48.6671428571 7.4926591084 63.4004192875 33.9338664268
SEA/GnJ 1 58.7766666667 8.0929968038 74.6904240305 42.8629093028
SEA/GnJ 2 48.2233333333 8.0929968038 64.1370906972 32.3095759695
SJL/J 1 31.733 6.2688083684 44.0597434492 19.4062565508
SJL/J 2 72.2216666667 8.0929968038 88.1354240305 56.3079093028
SM/J 1 51.0016666667 8.0929968038 66.9154240305 35.0879093028
SM/J 2 58.0007692308 5.498108651 68.8120384248 47.1895000367
SWR/J 1 67.6557142857 7.4926591084 82.3889907161 52.9224378553
SWR/J 2 46.9528571429 7.4926591084 61.6861335732 32.2195807125


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 26.3781666667 6.0019270653 38.1801249953 14.5762083381
A/J both 62.055 7.0087408249 75.8367181468 48.2732818532
AKR/J both 57.445 5.7226129201 68.6977257461 46.1922742539
ALR/LtJ both 45.4891964286 5.1298730117 55.5763812372 35.40201162
ALS/LtJ both 41.7195535714 5.1298730117 51.80673838 31.6323687628
BALB/cJ both 49.1488888889 4.6724938832 58.3367009867 39.961076791
BPH/2J both 46.458 5.6506275021 57.5691763914 35.3468236086
BPL/1J both 43.4235714286 4.9951060723 53.2457557155 33.6013871417
BPN/3J both 59.0768333333 6.0019270653 70.8787916619 47.2748750047
BTBR T+ Itpr3tf/J both 47.625 4.9951060723 57.4471842869 37.8028157131
BUB/BnJ both 49.7988333333 6.0019270653 61.6007916619 37.9968750047
C3H/HeJ both 55.2411111111 5.2240069737 65.5133973187 44.9688249035
C57BL/6J both 52.8 6.0019270653 64.6019583286 40.9980416714
C58/J both 37.389 5.1184605993 47.4537438802 27.3242561198
CAST/EiJ both 65.749875 5.6506275021 76.8610513914 54.6386986086
CBA/J both 47.2783333333 5.2240069737 57.550619541 37.0060471257
CE/J both 46.2162637363 4.6467499194 55.3534538946 37.0790735779
DBA/2J both 53.98225 6.6490753609 67.0567358243 40.9077641757
FVB/NJ both 42.8577142857 5.8037887891 54.2700611357 31.4453674357
I/LnJ both 53.999 6.2688083684 66.3257434492 41.6722565508
KK/HlJ both 43.7036111111 5.2240069737 53.9758973187 33.4313249035
LP/J both 32.008125 4.7016062763 41.2531825869 22.7630674131
MA/MyJ both 63.3952857143 5.8037887891 74.8076325643 51.9829388643
NOD/ShiLtJ both 56.7473484848 5.0304575825 66.6390466206 46.8556503491
NZB/BlNJ both 49.2471428571 4.8846161281 58.8520639713 39.642221743
PL/J both 52.075 5.6506275021 63.1861763914 40.9638236086
RIIIS/J both 46.3335714286 5.5144477915 57.1769692794 35.4901735777
SEA/GnJ both 53.5 5.7226129201 64.7527257461 42.2472742539
SJL/J both 51.9773333333 5.1184605993 62.0420772136 41.9125894531
SM/J both 54.5012179487 4.8919780254 64.1206152144 44.881820683
SWR/J both 57.3042857143 5.2981100647 67.7222853873 46.8862860413




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA