Project measure / variable:   Project1202   CFC.PS1_6_5XFAD_HFD

ID, description, units MPD:130414   CFC.PS1_6_5XFAD_HFD   CFC.PS1    6 5XFAD HFD  
Data set, strains Project1202   F1 AD-BXD   33 strains     sex: both
Procedure None
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  STRAIN COMPARISON PLOT
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Project1202 - CFC.PS1 6 5XFAD HFD



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested33 strains32 strains
Mean of the strain means21.905   None 25.809   None
Median of the strain means20.665   None 26.572   None
SD of the strain means± 9.9314 ± 11.078
Coefficient of variation (CV)0.4534 0.4292
Min–max range of strain means7.11   –   47.585   None 6.2857   –   54.0   None
Mean sample size per strain6.8   mice 7.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 619.9742 619.9742 2.2864 0.1313
strain 31 31278.0524 1008.9694 3.721 < 0.0001
sex:strain 31 14414.1962 464.9741 1.7148 0.0115
Residuals 381 103309.445 271.1534


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
(B6.5XFAD x BXD100)F1-ADtg f 7.11 12.315   3 7.11 1.7321 -1.49
(B6.5XFAD x BXD113)F1 f 13.811 10.325   7 3.9024 0.7476 2.67, 32.0 -0.81
(B6.5XFAD x BXD113)F1 m 24.381 22.057   7 8.3368 0.9047 -0.13
(B6.5XFAD x BXD124)F1 f 30.446 17.05   9 5.6832 0.56 2.67, 52.67 0.86
(B6.5XFAD x BXD124)F1 m 45.666 21.929   8 7.7531 0.4802 17.33, 86.0 1.79
(B6.5XFAD x BXD125)F1 f 21.704 16.526   9 5.5087 0.7614 -0.02
(B6.5XFAD x BXD125)F1 m 33.332 26.96   5 12.057 0.8088 3.33, 69.33 0.68
(B6.5XFAD x BXD12)F1 f 11.668 14.308   8 5.0586 1.2263 -1.03
(B6.5XFAD x BXD12)F1 m 35.714 13.405   7 5.0666 0.3753 16.67, 54.67 0.89
(B6.5XFAD x BXD14)F1-ADtg f 26.94 18.467   6 7.539 0.6855 2.31, 51.33 0.51
(B6.5XFAD x BXD14)F1-ADtg m 28.333 17.077   6 6.9718 0.6027 10.0, 59.33 0.23
(B6.5XFAD x BXD152)F1 f 37.524 15.074   7 5.6974 0.4017 20.0, 64.67 1.57
(B6.5XFAD x BXD152)F1 m 54.0 27.046   4 13.523 0.5008 18.67, 84.0 2.54
(B6.5XFAD x BXD154)F1 f 28.112 19.458   6 7.9437 0.6922 13.33, 64.67 0.63
(B6.5XFAD x BXD154)F1 m 6.2857 7.1151   7 2.6892 1.1319 -1.76
(B6.5XFAD x BXD161)F1 f 11.778 13.184   6 5.3824 1.1193 -1.02
(B6.5XFAD x BXD161)F1 m 14.399 14.111   10 4.4622 0.98 -1.03
(B6.5XFAD x BXD169)F1 f 10.778 14.35   6 5.8585 1.3314 -1.12
(B6.5XFAD x BXD169)F1 m 18.296 19.903   8 7.0369 1.0878 -0.68
(B6.5XFAD x BXD16)F1-ADtg f 33.665 10.109   6 4.127 0.3003 23.33, 52.0 1.18
(B6.5XFAD x BXD16)F1-ADtg m 25.926 15.446   9 5.1485 0.5958 0.01
(B6.5XFAD x BXD19)F1 f 10.191 17.303   7 6.5399 1.6978 -1.18
(B6.5XFAD x BXD19)F1 m 12.571 8.7383   7 3.3028 0.6951 3.33, 26.0 -1.2
(B6.5XFAD x BXD28)F1 f 19.334 17.95   7 6.7845 0.9284 -0.26
(B6.5XFAD x BXD28)F1 m 30.668 4.7429   4 2.3714 0.1547 26.67, 37.33 0.44
(B6.5XFAD x BXD38)F1 f 14.75 16.474   8 5.8245 1.1169 -0.72
(B6.5XFAD x BXD38)F1 m 20.777 7.0373   6 2.873 0.3387 11.33, 28.67 -0.45
(B6.5XFAD x BXD39)F1 f 33.732 11.082   5 4.9561 0.3285 20.0, 46.0 1.19
(B6.5XFAD x BXD39)F1 m 40.001 21.117   7 7.9815 0.5279 15.33, 78.0 1.28
(B6.5XFAD x BXD50)F1 f 29.223 19.743   6 8.06 0.6756 4.0, 58.0 0.74
(B6.5XFAD x BXD50)F1 m 26.477 21.353   7 8.0708 0.8065 2.67, 54.67 0.06
(B6.5XFAD x BXD55)F1-ADtg f 7.2371 14.517   7 5.4869 2.0059 -1.48
(B6.5XFAD x BXD55)F1-ADtg m 7.5544 9.7977   9 3.2659 1.2969 -1.65
(B6.5XFAD x BXD60)F1-ADtg f 16.888 18.469   6 7.5397 1.0936 0.67, 47.33 -0.51
(B6.5XFAD x BXD60)F1-ADtg m 22.777 15.081   6 6.1567 0.6621 -0.27
(B6.5XFAD x BXD61)F1-ADtg f 24.333 12.224   6 4.9906 0.5024 6.67, 35.33 0.24
(B6.5XFAD x BXD61)F1-ADtg m 23.407 11.317   9 3.7723 0.4835 1.33, 36.67 -0.22
(B6.5XFAD x BXD62)F1-ADtg f 26.888 15.974   6 6.5212 0.5941 2.67, 47.33 0.5
(B6.5XFAD x BXD62)F1-ADtg m 29.442 12.376   6 5.0523 0.4203 13.33, 43.33 0.33
(B6.5XFAD x BXD65)F1-ADtg f 11.81 5.3434   7 2.0196 0.4524 5.33, 19.33 -1.02
(B6.5XFAD x BXD65)F1-ADtg m 12.084 10.916   8 3.8596 0.9034 0.67, 36.0 -1.24
(B6.5XFAD x BXD66)F1-ADtg f 20.665 11.116   4 5.5578 0.5379 5.33, 31.33 -0.12
(B6.5XFAD x BXD66)F1-ADtg m 31.667 23.358   6 9.5357 0.7376 0.53
(B6.5XFAD x BXD68)F1-ADtg f 14.0 19.178   7 7.2487 1.3699 -0.8
(B6.5XFAD x BXD68)F1-ADtg m 26.666 17.538   7 6.6286 0.6577 3.33, 46.0 0.08
(B6.5XFAD x BXD73)F1 f 20.741 16.718   9 5.5727 0.806 -0.12
(B6.5XFAD x BXD73)F1 m 6.7767 3.0808   6 1.2577 0.4546 2.67, 10.0 -1.72
(B6.5XFAD x BXD74)F1 f 47.585 15.282   8 5.4032 0.3212 18.0, 72.67 2.59
(B6.5XFAD x BXD74)F1 m 31.75 16.117   8 5.6983 0.5076 8.0, 51.33 0.54
(B6.5XFAD x BXD75)F1-ADtg f 20.074 15.155   9 5.0518 0.755 5.33, 51.33 -0.18
(B6.5XFAD x BXD75)F1-ADtg m 29.8 18.866   10 5.9658 0.6331 0.36
(B6.5XFAD x BXD77)F1-ADtg f 18.193 17.147   7 6.4811 0.9425 0.67, 52.67 -0.37
(B6.5XFAD x BXD77)F1-ADtg m 22.191 19.939   7 7.5361 0.8985 -0.33
(B6.5XFAD x BXD83)F1 f 15.0 16.089   4 8.0446 1.0726 2.67, 38.67 -0.7
(B6.5XFAD x BXD83)F1 m 30.286 12.666   7 4.7871 0.4182 14.67, 52.0 0.4
(B6.5XFAD x BXD87)F1-ADtg f 39.526 25.794   7 9.7491 0.6526 10.67, 82.67 1.77
(B6.5XFAD x BXD87)F1-ADtg m 16.297 21.664   9 7.2213 1.3293 -0.86
(B6.5XFAD x BXD99)F1-ADtg f 25.746 11.858   5 5.303 0.4606 8.05, 36.67 0.39
(B6.5XFAD x BXD99)F1-ADtg m 33.308 11.67   6 4.7644 0.3504 18.67, 46.67 0.68
(B6.5XFAD x D2)F1-ADtg f 31.553 11.46   6 4.6786 0.3632 15.33, 43.33 0.97
(B6.5XFAD x D2)F1-ADtg m 34.443 21.921   3 12.656 0.6364 18.0, 59.33 0.78
(B6 x DBA/2J-Gpnmb+/SjJ)F1 f 15.916 15.391   8 5.4417 0.967 0.67, 42.67 -0.6
(B6 x DBA/2J-Gpnmb+/SjJ)F1 m 35.43 20.115   7 7.6026 0.5677 4.67, 58.0 0.87
C57BL/6J f 25.939 20.761   11 6.2598 0.8004 2.67, 70.0 0.41
C57BL/6J m 15.186 15.353   9 5.1176 1.011 -0.96


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ 1 7.2371428571 6.2238412469 19.4745211851 -5.0002354709
129S1/SvImJ 2 7.5544444444 5.4889120462 18.3467976962 -3.2379088073
A/J 1 16.8883333333 6.7225168782 30.1062126287 3.670454038
A/J 2 22.7766666667 6.7225168782 35.994545962 9.5587873713
AKR/J 1 13.8114285714 6.2238412469 26.0488068994 1.5740502434
AKR/J 2 24.3814285714 6.2238412469 36.6188068994 12.1440502434
ALR/LtJ 1 37.5242857143 6.2238412469 49.7616640423 25.2869073863
ALR/LtJ 2 54.0025 8.2333680694 70.1910298777 37.8139701223
ALS/LtJ 1 28.1116666667 6.7225168782 41.329545962 14.8937873713
ALS/LtJ 2 6.2857142857 6.2238412469 18.5230926137 -5.9516640423
BALB/cJ 1 24.3333333333 6.7225168782 37.5512126287 11.115454038
BALB/cJ 2 23.4066666667 5.4889120462 34.1990199184 12.6143134149
BPH/2J 1 11.7783333333 6.7225168782 24.9962126287 -1.439545962
BPH/2J 2 14.399 5.2072391827 24.6375252766 4.1604747234
BPL/1J 1 21.7044444444 5.4889120462 32.4967976962 10.9120911927
BPL/1J 2 33.332 7.3641482747 47.8114613049 18.8525386951
BPN/3J 1 14.75 5.8218703938 26.1970192539 3.3029807461
BPN/3J 2 20.7766666667 6.7225168782 33.994545962 7.5587873713
BTBR T+ Itpr3tf/J 1 26.94 6.7225168782 40.1578792954 13.7221207046
BTBR T+ Itpr3tf/J 2 28.3333333333 6.7225168782 41.5512126287 15.115454038
BUB/BnJ 1 10.7783333333 6.7225168782 23.9962126287 -2.439545962
BUB/BnJ 2 18.29625 5.8218703938 29.7432692539 6.8492307461
C3H/HeJ 1 26.8883333333 6.7225168782 40.1062126287 13.670454038
C3H/HeJ 2 29.4416666667 6.7225168782 42.659545962 16.2237873713
C57BL/6J 1 11.81 6.2238412469 24.047378328 -0.427378328
C57BL/6J 2 12.08375 5.8218703938 23.5307692539 0.6367307461
C57BR/cdJ 1 25.9390909091 4.964907754 35.7011417294 16.1770400888
C57BR/cdJ 2 15.1855555556 5.4889120462 25.9779088073 4.3932023038
C58/J 1 33.732 7.3641482747 48.2114613049 19.2525386951
C58/J 2 40.0014285714 6.2238412469 52.2388068994 27.7640502434
CAST/EiJ 1 33.665 6.7225168782 46.8828792954 20.4471207046
CAST/EiJ 2 25.9255555556 5.4889120462 36.7179088073 15.1332023038
CBA/J 1 11.6675 5.8218703938 23.1145192539 0.2204807461
CBA/J 2 35.7142857143 6.2238412469 47.9516640423 23.4769073863
CE/J 1 10.1914285714 6.2238412469 22.4288068994 -2.0459497566
CE/J 2 12.5714285714 6.2238412469 24.8088068994 0.3340502434
DBA/2J 1 20.665 8.2333680694 36.8535298777 4.4764701223
DBA/2J 2 31.6666666667 6.7225168782 44.884545962 18.4487873713
FVB/NJ 1 14.0 6.2238412469 26.237378328 1.762621672
FVB/NJ 2 26.6657142857 6.2238412469 38.9030926137 14.4283359577
I/LnJ 1 47.585 5.8218703938 59.0320192539 36.1379807461
I/LnJ 2 31.75 5.8218703938 43.1970192539 20.3029807461
KK/HlJ 1 30.4455555556 5.4889120462 41.2379088073 19.6532023038
KK/HlJ 2 45.66625 5.8218703938 57.1132692539 34.2192307461
LP/J 1 20.0744444444 5.4889120462 30.8667976962 9.2820911927
LP/J 2 29.8 5.2072391827 40.0385252766 19.5614747234
MA/MyJ 1 29.2233333333 6.7225168782 42.4412126287 16.005454038
MA/MyJ 2 26.4771428571 6.2238412469 38.7145211851 14.2397645291
NOD/ShiLtJ 1 25.746 7.3641482747 40.2254613049 11.2665386951
NOD/ShiLtJ 2 33.3083333333 6.7225168782 46.5262126287 20.090454038
NZB/BlNJ 1 18.1928571429 6.2238412469 30.4302354709 5.9554788149
NZB/BlNJ 2 22.1914285714 6.2238412469 34.4288068994 9.9540502434
PL/J 1 31.5533333333 6.7225168782 44.7712126287 18.335454038
PL/J 2 34.4433333333 9.5070745424 53.1362374986 15.750429168
RIIIS/J 1 19.3342857143 6.2238412469 31.5716640423 7.0969073863
RIIIS/J 2 30.6675 8.2333680694 46.8560298777 14.4789701223
SEA/GnJ 1 20.7411111111 5.4889120462 31.5334643629 9.9487578593
SEA/GnJ 2 6.7766666667 6.7225168782 19.994545962 -6.4412126287
SJL/J 1 15.91625 5.8218703938 27.3632692539 4.4692307461
SJL/J 2 35.43 6.2238412469 47.667378328 23.192621672
SM/J 1 15.0 8.2333680694 31.1885298777 -1.1885298777
SM/J 2 30.2857142857 6.2238412469 42.5230926137 18.0483359577
SWR/J 1 39.5257142857 6.2238412469 51.7630926137 27.2883359577
SWR/J 2 16.2966666667 5.4889120462 27.0890199184 5.5043134149


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 7.3957936508 4.1492274979 15.5540458695 -0.7624585679
A/J both 19.8325 4.7535372712 29.1789520826 10.4860479174
AKR/J both 19.0964285714 4.4009203507 27.7495617711 10.4432953718
ALR/LtJ both 45.7633928571 5.1605365426 55.91009094 35.6166947742
ALS/LtJ both 17.1986904762 4.5806231302 26.2051570615 8.1922238909
BALB/cJ both 23.87 4.3393659856 32.4021043972 15.3378956028
BPH/2J both 13.0886666667 4.2516929888 21.4483875488 4.7289457846
BPL/1J both 27.5182222222 4.5923532982 36.5477527802 18.4886916642
BPN/3J both 17.7633333333 4.446526961 26.5061387021 9.0205279645
BTBR T+ Itpr3tf/J both 27.6366666667 4.7535372712 36.9831187493 18.290214584
BUB/BnJ both 14.5372916667 4.446526961 23.2800970355 5.7944862979
C3H/HeJ both 28.165 4.7535372712 37.5114520826 18.8185479174
C57BL/6J both 11.946875 4.2611728065 20.3252351937 3.5685148063
C57BR/cdJ both 20.5623232323 3.7006237466 27.8385263103 13.2861201543
C58/J both 36.8667142857 4.8209666997 46.3457467788 27.3876817926
CAST/EiJ both 29.7952777778 4.3393659856 38.327382175 21.2631733806
CBA/J both 23.6908928571 4.2611728065 32.0692530509 15.3125326634
CE/J both 11.3814285714 4.4009203507 20.0345617711 2.7282953718
DBA/2J both 26.1658333333 5.314616236 36.615484436 15.7161822307
FVB/NJ both 20.3328571429 4.4009203507 28.9859903425 11.6797239432
I/LnJ both 39.6675 4.1166840347 47.7617649388 31.5732350612
KK/HlJ both 38.0559027778 4.0006977621 45.9221143582 30.1896911974
LP/J both 24.9372222222 3.7829715621 32.3753383908 17.4991060536
MA/MyJ both 27.8502380952 4.5806231302 36.8567046805 18.8437715099
NOD/ShiLtJ both 29.5271666667 4.9855519501 39.3298083099 19.7245250234
NZB/BlNJ both 20.1921428571 4.4009203507 28.8452760568 11.5390096575
PL/J both 32.9983333333 5.8218703938 44.4453525873 21.5513140794
RIIIS/J both 25.0008928571 5.1605365426 35.14759094 14.8541947742
SEA/GnJ both 13.7588888889 4.3393659856 22.2909932861 5.2267844917
SJL/J both 25.673125 4.2611728065 34.0514851937 17.2947648063
SM/J both 22.6428571429 5.1605365426 32.7895552258 12.49615906
SWR/J both 27.9111904762 4.1492274979 36.0694426949 19.7529382575




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA