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Project measure / variable:   Project1202   CFC.PS1_22_5XFAD_Chow

ID, description, units MPD:130404   CFC.PS1_22_5XFAD_Chow   CFC.PS1    22 5XFAD Chow  
Data set, strains Project1202   F1 AD-BXD   23 strains     sex: both
Procedure None
Ontology mappings


  STRAIN COMPARISON PLOT
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Project1202 - CFC.PS1 22 5XFAD Chow



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested17 strains18 strains
Mean of the strain means24.625   None 48.377   None
Median of the strain means27.172   None 48.216   None
SD of the strain means± 14.834 ± 18.821
Coefficient of variation (CV)0.6024 0.389
Min–max range of strain means0.0   –   58.05   None 7.84   –   90.0   None
Mean sample size per strain3.4   mice 4.3   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 17451.2686 17451.2686 32.1229 < 0.0001
strain 7 8829.1874 1261.3125 2.3217 0.0345
sex:strain 7 3051.1791 435.8827 0.8023 0.5881
Residuals 70 38028.6033 543.2658


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
(B6.5XFAD x BXD124)F1 f 37.665 41.953   2   29.665 1.1138 8.0, 67.33 0.88
(B6.5XFAD x BXD125)F1 f 30.668 17.996   4 8.9978 0.5868 6.67, 46.67 0.41
(B6.5XFAD x BXD125)F1 m 49.918 26.752   4 13.376 0.5359 14.0, 78.67 0.08
(B6.5XFAD x BXD14)F1-ADtg f 0.0 0.0   1   0.0 None -1.66
(B6.5XFAD x BXD14)F1-ADtg m 54.89 18.016   3 10.401 0.3282 41.33, 75.33 0.35
(B6.5XFAD x BXD152)F1 f 58.05 4.5437   3 2.6233 0.0783 52.8, 60.67 2.25
(B6.5XFAD x BXD152)F1 m 66.53 14.737   5 6.5905 0.2215 48.67, 86.67 0.96
(B6.5XFAD x BXD154)F1 f 40.665 12.254   2   8.665 0.3013 32.0, 49.33 1.08
(B6.5XFAD x BXD161)F1 f 13.0 6.1235   2   4.33 0.471 8.67, 17.33 -0.78
(B6.5XFAD x BXD161)F1 m 48.898 33.695   4 16.847 0.6891 0.03
(B6.5XFAD x BXD169)F1 f 14.703 23.032   9 7.6772 1.5664 -0.67
(B6.5XFAD x BXD169)F1 m 26.834 16.761   7 6.3352 0.6246 10.56, 59.63 -1.14
(B6.5XFAD x BXD172)F1 f 36.0 0.0   1   0.0 0.0 36.0, 36.0 0.77
(B6.5XFAD x BXD216)F1 m 45.653 20.426   4 10.213 0.4474 21.12, 66.46 -0.14
(B6.5XFAD x BXD28)F1 f 15.33 0.0   1   0.0 0.0 15.33, 15.33 -0.63
(B6.5XFAD x BXD50)F1 m 43.683 36.353   3 20.988 0.8322 13.04, 83.85 -0.25
(B6.5XFAD x BXD60)F1-ADtg f 16.79 18.344   4 9.1718 1.0925 1.86, 43.48 -0.53
(B6.5XFAD x BXD60)F1-ADtg m 37.985 35.643   4 17.822 0.9384 6.0, 78.0 -0.55
(B6.5XFAD x BXD61)F1-ADtg f 6.4933 4.6239   3 2.6696 0.7121 3.33, 11.8 -1.22
(B6.5XFAD x BXD61)F1-ADtg m 48.787 25.444   7 9.617 0.5215 3.73, 71.33 0.02
(B6.5XFAD x BXD65)F1-ADtg m 32.335 34.415   2   24.335 1.0643 8.0, 56.67 -0.85
(B6.5XFAD x BXD66)F1-ADtg f 39.0 32.527   2   23.0 0.834 16.0, 62.0 0.97
(B6.5XFAD x BXD66)F1-ADtg m 90.0 0.0   1   0.0 0.0 90.0, 90.0 2.21
(B6.5XFAD x BXD68)F1-ADtg f 10.583 11.998   6 4.8983 1.1337 -0.95
(B6.5XFAD x BXD68)F1-ADtg m 47.646 9.201   5 4.1148 0.1931 37.33, 61.87 -0.04
(B6.5XFAD x BXD73a)F1 f 27.172 28.1   4 14.05 1.0341 0.17
(B6.5XFAD x BXD73)F1 f 28.0 0.0   1   0.0 0.0 28.0, 28.0 0.23
(B6.5XFAD x BXD73)F1 m 39.443 20.528   6 8.3805 0.5204 12.0, 60.0 -0.47
(B6.5XFAD x BXD81)F1-ADtg m 7.84 8.6146   5 3.8526 1.0988 -2.15
(B6.5XFAD x BXD99)F1-ADtg m 78.34 2.3547   2   1.665 0.0301 76.67, 80.0 1.59
(B6.5XFAD x D2)F1-ADtg f 27.777 25.018   3 14.444 0.9007 3.33, 53.33 0.21
(B6.5XFAD x D2)F1-ADtg m 63.33 0.0   1   0.0 0.0 63.33, 63.33 0.79
(B6 x DBA/2J-Gpnmb+/SjJ)F1 f 16.732 18.749   10 5.9289 1.1205 -0.53
(B6 x DBA/2J-Gpnmb+/SjJ)F1 m 53.77 38.173   9 12.724 0.7099 0.29
C57BL/6J m 34.906 19.258   5 8.6122 0.5517 13.66, 54.66 -0.72


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ 1 10.5833333333 9.5154765324 29.5613528657 -8.3946861991
129S1/SvImJ 2 47.646 10.4236822844 68.4353787893 26.8566212107
A/J 1 16.732 7.3706564282 31.4323107186 2.0316892814
A/J 2 53.7744444444 7.7693540546 69.2699325054 38.2789563835
BALB/cJ 1 30.6675 11.6540310819 53.9107320915 7.4242679085
BALB/cJ 2 49.9175 11.6540310819 73.1607320915 26.6742679085
BTBR T+ Itpr3tf/J 1 16.79 11.6540310819 40.0332320915 -6.4532320915
BTBR T+ Itpr3tf/J 2 37.985 11.6540310819 61.2282320915 14.7417679085
C3H/HeJ 1 58.0466666667 13.4569159646 84.8856392764 31.207694057
C3H/HeJ 2 66.534 10.4236822844 87.3233787893 45.7446212107
C57BL/6J 1 13.0 16.4812888123 45.8708940571 -19.8708940571
C57BL/6J 2 48.8975 11.6540310819 72.1407320915 25.6542679085
CAST/EiJ 1 6.4933333333 13.4569159646 33.332305943 -20.3456392764
CAST/EiJ 2 48.7871428571 8.8096194326 66.3573747941 31.2169109202
DBA/2J 1 14.7033333333 7.7693540546 30.1988213943 -0.7921547276
DBA/2J 2 26.8342857143 8.8096194326 44.4045176512 9.2640537773


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 29.1146666667 7.0568662664 43.1891426411 15.0401906922
A/J both 35.2532222222 5.354657753 45.9327503657 24.5736940787
BALB/cJ both 40.2925 8.2406444062 56.7279470286 23.8570529714
BTBR T+ Itpr3tf/J both 27.3875 8.2406444062 43.8229470286 10.9520529714
C3H/HeJ both 62.2903333333 8.5109009459 79.2647900344 45.3158766322
C57BL/6J both 30.94875 10.0926869734 51.0779794573 10.8195205427
CAST/EiJ both 27.6402380952 8.0420454771 43.6795920494 11.6008841411
DBA/2J both 20.7688095238 5.8730796217 32.4822974818 9.0553215658




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA