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Project measure / variable:   Bennett4   AST_base_HFHS

ID, description, units MPD:114738   AST_base_HFHS   plasma aspartate aminotransferase (AST) amount, baseline   [U/L]  HFHS group  
various diets 2 study
Data set, strains Bennett4   CC   22 strains     sex: f     age: 8-11wks
Procedure metabolic panel
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  STRAIN COMPARISON PLOT
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Bennett4 - plasma aspartate aminotransferase (AST) amount, baseline HFHS group



  MEASURE SUMMARY
Measure Summary Female
Number of strains tested22 strains
Mean of the strain means275.2   U/L
Median of the strain means227.8   U/L
SD of the strain means± 140.0
Coefficient of variation (CV)0.5089
Min–max range of strain means95.91   –   570.0   U/L
Mean sample size per strain4.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 21 1767074.6633 84146.4125 1.4143 0.1374
Residuals 79 4700342.4417 59498.0056


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
CC001/Unc f 327.2 148.2   5 66.26 0.4528 166.5, 510.3 0.37
CC002/Unc f 172.1 44.427   5 19.869 0.2582 99.9, 210.3 -0.74
CC004/TauUnc f 200.0 122.5   5 54.77 0.6122 105.6, 374.4 -0.54
CC006/TauUnc f 570.0 452.0   4 226.0 0.793 177.6, 990.6 2.11
CC008/GeniUnc f 281.9 207.6   4 103.8 0.7364 128.8, 583.2 0.05
CC011/Unc f 95.91 21.704   5 9.7062 0.2263 75.15, 130.2 -1.28
CC012/GeniUnc f 211.8 42.166   5 18.857 0.1991 142.5, 247.5 -0.45
CC019/TauUnc f 158.8 63.85   5 28.555 0.4022 85.8, 237.2 -0.83
CC024/GeniUnc f 170.7 36.911   2   26.1 0.2162 144.6, 196.8 -0.75
CC027/GeniUnc f 377.5 430.2   5 192.4 1.1398 71.1, 1066.0 0.73
CC028/GeniUnc f 243.8 100.3   4 50.13 0.4112 165.3, 378.0 -0.22
CC030/GeniUnc f 130.7 8.5307   5 3.815 0.0653 122.0, 140.1 -1.03
CC032/GeniUnc f 157.3 67.08   5 29.999 0.4266 85.2, 240.9 -0.84
CC035/Unc f 169.7 50.76   5 22.701 0.2992 105.9, 238.5 -0.75
CC036/Unc f 142.2 50.35   5 22.517 0.3541 88.05, 222.9 -0.95
CC037/TauUnc f 179.3 96.88   5 43.328 0.5403 93.0, 339.1 -0.68
CC040/TauUnc f 465.1 401.3   5 179.5 0.8628 198.9, 1117.0 1.36
CC041/TauUnc f 416.0 163.2   5 72.97 0.3922 226.5, 614.2 1.01
CC045/GeniUnc f 277.4 23.513   4 11.757 0.0848 243.9, 296.1 0.02
CC059/TauUnc f 335.0 246.8   5 110.4 0.7368 154.5, 758.1 0.43
CC063/Unc f 565.8 668.4   3 385.9 1.1814 126.5, 1335.0 2.08
CC071/TauUnc f 406.1 509.7   5 227.9 1.2549 94.95, 1310.0 0.93


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
CC001/Unc f 327.2 109.085292859 544.3288441043 110.0711558957
CC002/Unc f 172.08 109.085292859 389.2088441043 -45.0488441043
CC004/TauUnc f 200.04 109.085292859 417.1688441043 -17.0888441043
CC006/TauUnc f 570.0 121.9610650891 812.7574276466 327.2425723534
CC008/GeniUnc f 281.95 121.9610650891 524.7074276466 39.1925723534
CC011/Unc f 95.91 109.085292859 313.0388441043 -121.2188441043
CC012/GeniUnc f 211.8 109.085292859 428.9288441043 -5.3288441043
CC019/TauUnc f 158.76 109.085292859 375.8888441043 -58.3688441043
CC024/GeniUnc f 170.7 172.4789923305 514.0108465446 -172.6108465446
CC027/GeniUnc f 377.46 109.085292859 594.5888441043 160.3311558957
CC028/GeniUnc f 243.825 121.9610650891 486.5824276466 1.0675723534
CC030/GeniUnc f 130.66 109.085292859 347.7888441043 -86.4688441043
CC032/GeniUnc f 157.26 109.085292859 374.3888441043 -59.8688441043
CC035/Unc f 169.68 109.085292859 386.8088441043 -47.4488441043
CC036/Unc f 142.21 109.085292859 359.3388441043 -74.9188441043
CC037/TauUnc f 179.3 109.085292859 396.4288441043 -37.8288441043
CC040/TauUnc f 465.14 109.085292859 682.2688441043 248.0111558957
CC041/TauUnc f 416.0 109.085292859 633.1288441043 198.8711558957
CC045/GeniUnc f 277.425 121.9610650891 520.1824276466 34.6675723534
CC059/TauUnc f 335.02 109.085292859 552.1488441043 117.8911558957
CC063/Unc f 565.7666666667 140.8285075197 846.0787990657 285.4545342676
CC071/TauUnc f 406.15 109.085292859 623.2788441043 189.0211558957




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA