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Project measure / variable:   Auwerx2   kidney_wt_HFD

ID, description, units MPD:114660   kidney_wt_HFD   kidney weight (both)   [g]  HFD  
Data set, strains Auwerx2   inbred w/CC8   9 strains     sex: both     age: 21wks
Procedure organ weights
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  STRAIN COMPARISON PLOT
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Auwerx2 - kidney weight (both) HFD



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested9 strains9 strains
Mean of the strain means0.28683   g 0.37925   g
Median of the strain means0.26972   g 0.33263   g
SD of the strain means± 0.11195 ± 0.14759
Coefficient of variation (CV)0.3903 0.3892
Min–max range of strain means0.15666   –   0.55012   g 0.2075   –   0.6451   g
Mean sample size per strain4.4   mice 3.7   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.1711 0.1711 249.574 < 0.0001
strain 7 0.4064 0.0581 84.678 < 0.0001
sex:strain 7 0.1018 0.0145 21.2067 < 0.0001
Residuals 51 0.035 0.0007


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 0.2559 0.01933   5 0.00864245 0.0755 0.2328, 0.2844 -0.28
129S1/SvImJ m 0.34295 0.01662   2   0.01175 0.0485 0.3312, 0.3547 -0.25
A/J f 0.26972 0.0198   4 0.00990138 0.0734 0.2488, 0.2935 -0.15
A/J m 0.26714 0.01954   5 0.00873891 0.0731 0.2345, 0.2871 -0.76
C57BL/6J f 0.27463 0.02195   3 0.01267 0.0799 0.2555, 0.2986 -0.11
C57BL/6J m 0.33263 0.03162   4 0.01581 0.095 0.289, 0.3647 -0.32
CAST/EiJ f 0.15666 0.01028   5 0.00459778 0.0656 0.147, 0.1698 -1.16
CAST/EiJ m 0.2075 0.01442   2   0.0102 0.0695 0.1973, 0.2177 -1.16
DBA/2J f 0.34024 0.02611   5 0.01168 0.0767 0.304, 0.3764 0.48
DBA/2J m 0.58928 0.05444   5 0.02434 0.0924 0.5241, 0.6696 1.42
NOD/ShiLtJ f 0.27498 0.01999   6 0.00816008 0.0727 0.2518, 0.3024 -0.11
NOD/ShiLtJ m 0.42435 0.00874166   4 0.00437083 0.0206 0.4156, 0.4326 0.31
NZO/HlLtJ f 0.55012 0.01663   5 0.00743716 0.0302 0.5261, 0.5726 2.35
NZO/HlLtJ m 0.6451 0.0   1   0.0 0.0 0.6451, 0.6451 1.8
PWK/PhJ f 0.2687 0.00169706   4 0.00084853 0.0063 0.2663, 0.2699 -0.16
PWK/PhJ m 0.30148 0.02681   5 0.01199 0.0889 0.2759, 0.3418 -0.53
WSB/EiJ f 0.19053 0.00413562   3 0.0023877 0.0217 0.1879, 0.1953 -0.86
WSB/EiJ m 0.3028 0.03928   5 0.01757 0.1297 0.2622, 0.367 -0.52


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 0.2559 0.0117096012 0.2794080053 0.2323919947
129S1/SvImJ m 0.34295 0.0185145051 0.3801194199 0.3057805801
A/J f 0.269725 0.0130917321 0.2960077489 0.2434422511
A/J m 0.26714 0.0117096012 0.2906480053 0.2436319947
C57BL/6J f 0.2746333333 0.0151170301 0.3049820376 0.244284629
C57BL/6J m 0.332625 0.0130917321 0.3589077489 0.3063422511
CAST/EiJ f 0.15666 0.0117096012 0.1801680053 0.1331519947
CAST/EiJ m 0.2075 0.0185145051 0.2446694199 0.1703305801
DBA/2J f 0.34024 0.0117096012 0.3637480053 0.3167319947
DBA/2J m 0.58928 0.0117096012 0.6127880053 0.5657719947
NOD/ShiLtJ f 0.2749833333 0.0106893545 0.2964431079 0.2535235587
NOD/ShiLtJ m 0.42435 0.0130917321 0.4506327489 0.3980672511
PWK/PhJ f 0.2687 0.0130917321 0.2949827489 0.2424172511
PWK/PhJ m 0.30148 0.0117096012 0.3249880053 0.2779719947
WSB/EiJ f 0.1905333333 0.0151170301 0.2208820376 0.160184629
WSB/EiJ m 0.3028 0.0117096012 0.3263080053 0.2792919947


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 0.299425 0.0109533289 0.3214147254 0.2774352746
A/J both 0.2684325 0.0087822009 0.2860635039 0.2508014961
C57BL/6J both 0.3036291667 0.0099989756 0.3237029477 0.2835553856
CAST/EiJ both 0.18208 0.0109533289 0.2040697254 0.1600902746
DBA/2J both 0.46476 0.0082799384 0.4813826699 0.4481373301
NOD/ShiLtJ both 0.3496666667 0.0084506767 0.3666321081 0.3327012252
PWK/PhJ both 0.28509 0.0087822009 0.3027210039 0.2674589961
WSB/EiJ both 0.2466666667 0.0095608493 0.2658608726 0.2274724607




  GWAS USING LINEAR MIXED MODELS