Project measure / variable:   Auwerx2   horiz_act_night_CD

ID, description, units MPD:114627   horiz_act_night_CD   horizontal activity (beam breaks) at night, basal activity test, for 48h   [n/h]  CD  
Data set, strains Auwerx2   inbred w/CC8   9 strains     sex: both     age: 19wks
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  STRAIN COMPARISON PLOT
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Auwerx2 - horizontal activity (beam breaks) at night, basal activity test, for 48h CD



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested9 strains9 strains
Mean of the strain means93845.0   n/h 62452.0   n/h
Median of the strain means76268.0   n/h 56217.0   n/h
SD of the strain means± 79304.0 ± 35308.0
Coefficient of variation (CV)0.845 0.5654
Min–max range of strain means25725.0   –   294248.0   n/h 23190.0   –   145709.0   n/h
Mean sample size per strain4.3   mice 4.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 6773034405.8089 6773034405.8089 21.008 < 0.0001
strain 7 23155043373.6348 3307863339.0907 10.2601 < 0.0001
sex:strain 7 10744476588.7178 1534925226.9597 4.7609 0.0002
Residuals 62 19988917540.3 322401895.8113


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 52890.0 11394.0   5 5096.0 0.2154 38732.0, 66386.0 -0.52
129S1/SvImJ m 44519.0 16387.0   5 7328.0 0.3681 32602.0, 71755.0 -0.51
A/J f 98287.0 28349.0   5 12678.0 0.2884 68264.0, 144431.0 0.06
A/J m 60896.0 14582.0   5 6521.0 0.2395 50689.0, 83988.0 -0.04
C57BL/6J f 107851.0 20101.0   5 8990.0 0.1864 88369.0, 139131.0 0.18
C57BL/6J m 42480.0 4796.0   5 2145.0 0.1129 38930.0, 50562.0 -0.57
CAST/EiJ f 294248.0 0.0   1   0.0 0.0 294248.0, 294248.0 2.53
CAST/EiJ m 145709.0 178891.0   3 103283.0 1.2277 31104.0, 351844.0 2.36
DBA/2J f 76268.0 10845.0   5 4850.0 0.1422 61756.0, 90853.0 -0.22
DBA/2J m 77183.0 26032.0   5 11642.0 0.3373 59005.0, 120700.0 0.42
NOD/ShiLtJ f 59593.0 18922.0   6 7725.0 0.3175 36339.0, 93884.0 -0.43
NOD/ShiLtJ m 70704.0 13008.0   5 5818.0 0.184 56536.0, 88030.0 0.23
NZO/HlLtJ f 25725.0 3609.0   4 1804.0 0.1403 20699.0, 28441.0 -0.86
NZO/HlLtJ m 23190.0 5566.0   5 2489.0 0.24 17516.0, 31187.0 -1.11
PWK/PhJ f 79988.0 34325.0   5 15351.0 0.4291 43590.0, 113704.0 -0.17
PWK/PhJ m 56217.0 15272.0   5 6830.0 0.2717 32036.0, 71806.0 -0.18
WSB/EiJ f 49757.0 15507.0   3 8953.0 0.3117 39081.0, 67545.0 -0.56
WSB/EiJ m 41171.0 13076.0   5 5848.0 0.3176 26362.0, 59325.0 -0.6


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 52889.8 8029.9675691909 68941.4764535145 36838.1235464856
129S1/SvImJ m 44519.0000000001 8029.9675691909 60570.6764535145 28467.3235464856
A/J f 98287.4000000001 8029.9675691909 114339.0764535145 82235.7235464857
A/J m 60896.0000000001 8029.9675691909 76947.6764535145 44844.3235464857
C57BL/6J f 107850.6 8029.9675691909 123902.2764535144 91798.9235464856
C57BL/6J m 42480.1999999999 8029.9675691909 58531.8764535143 26428.5235464855
DBA/2J f 76268.2 8029.9675691909 92319.8764535144 60216.5235464856
DBA/2J m 77182.9999999999 8029.9675691909 93234.6764535143 61131.3235464855
NOD/ShiLtJ f 59593.1666666666 7330.3239561347 74246.2754656072 44940.057867726
NOD/ShiLtJ m 70703.9999999999 8029.9675691909 86755.6764535143 54652.3235464855
NZO/HlLtJ f 25725.0 8977.7766709148 43671.3198514454 7778.6801485545
NZO/HlLtJ m 23189.7999999999 8029.9675691909 39241.4764535143 7138.1235464855
PWK/PhJ f 79987.8 8029.9675691909 96039.4764535144 63936.1235464856
PWK/PhJ m 56217.3999999999 8029.9675691909 72269.0764535144 40165.7235464855
WSB/EiJ f 49757.3333333333 10366.643555354 70479.9585277237 29034.708138943
WSB/EiJ m 41171.3999999999 8029.9675691909 57223.0764535143 25119.7235464855


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 48704.4 5678.044520883 60054.6492696925 37354.1507303076
A/J both 79591.7000000001 5678.044520883 90941.9492696926 68241.4507303076
C57BL/6J both 75165.4 5678.044520883 86515.6492696924 63815.1507303075
DBA/2J both 76725.6 5678.044520883 88075.8492696924 65375.3507303075
NOD/ShiLtJ both 65148.5833333333 5436.3137433407 76015.6196639284 54281.5470027381
NZO/HlLtJ both 24457.3999999999 6022.4756768932 36496.1573401358 12418.6426598641
PWK/PhJ both 68102.6 5678.044520883 79452.8492696924 56752.3507303075
WSB/EiJ both 45464.3666666666 6556.4410652049 58570.5056091192 32358.227724214




  GWAS USING LINEAR MIXED MODELS