Project measure / variable:   Auwerx2   temp_t6_CD

ID, description, units MPD:114619   temp_t6_CD   body temperature (rectal) in cold (4°C) room, 6h exposed to cold   [°C]  CD  
Data set, strains Auwerx2   inbred w/CC8   9 strains     sex: both     age: 18wks
Procedure body temperature
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  STRAIN COMPARISON PLOT
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Auwerx2 - body temperature (rectal) in cold (4°C) room, 6h exposed to cold CD



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested9 strains9 strains
Mean of the strain means34.439   °C 34.258   °C
Median of the strain means34.3   °C 34.16   °C
SD of the strain means± 0.84798 ± 1.1748
Coefficient of variation (CV)0.0246 0.0343
Min–max range of strain means33.05   –   35.9   °C 32.8   –   36.1   °C
Mean sample size per strain4.0   mice 4.3   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 1.7488 1.7488 2.6799 0.1072
strain 7 58.5307 8.3615 12.8138 < 0.0001
sex:strain 7 10.1934 1.4562 2.2316 0.0449
Residuals 56 36.5422 0.6525


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 33.96 0.89051   5 0.39825 0.0262 33.1, 35.0 -0.56
129S1/SvImJ m 34.14 0.40373   5 0.18055 0.0118 33.6, 34.7 -0.1
A/J f 34.3 0.81548   5 0.36469 0.0238 33.4, 35.2 -0.16
A/J m 34.74 0.56391   5 0.25219 0.0162 33.8, 35.3 0.41
C57BL/6J f 33.05 1.3435   2   0.95 0.0407 32.1, 34.0 -1.64
C57BL/6J m 32.8 0.5099   4 0.25495 0.0155 32.1, 33.3 -1.24
CAST/EiJ f 34.0 0.0   1   0.0 0.0 34.0, 34.0 -0.52
CAST/EiJ m 34.45 0.91924   2   0.65 0.0267 33.8, 35.1 0.16
DBA/2J f 35.22 0.81363   5 0.36387 0.0231 34.5, 36.2 0.92
DBA/2J m 34.16 0.24083   5 0.1077 0.0071 33.9, 34.5 -0.08
NOD/ShiLtJ f 33.95 1.5372   6 0.62756 0.0453 31.5, 35.5 -0.58
NOD/ShiLtJ m 33.16 1.23   5 0.55009 0.0371 31.8, 34.7 -0.93
NZO/HlLtJ f 34.5 0.34641   4 0.17321 0.01 34.2, 35.0 0.07
NZO/HlLtJ m 32.975 0.68981   4 0.3449 0.0209 32.1, 33.7 -1.09
PWK/PhJ f 35.9 0.61644   5 0.27568 0.0172 35.2, 36.8 1.72
PWK/PhJ m 35.8 0.57879   5 0.25884 0.0162 35.0, 36.4 1.31
WSB/EiJ f 35.067 0.23094   3 0.13333 0.0066 34.8, 35.2 0.74
WSB/EiJ m 36.1 0.48305   4 0.24152 0.0134 35.4, 36.5 1.57


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 33.96 0.3612585474 34.6836878323 33.2363121677
129S1/SvImJ m 34.14 0.3612585474 34.8636878323 33.4163121677
A/J f 34.3 0.3612585474 35.0236878323 33.5763121677
A/J m 34.74 0.3612585474 35.4636878323 34.0163121677
C57BL/6J f 33.05 0.5711999171 34.1942509324 31.9057490676
C57BL/6J m 32.8 0.4038993348 33.6091075937 31.9908924063
DBA/2J f 35.22 0.3612585474 35.9436878323 34.4963121677
DBA/2J m 34.16 0.3612585474 34.8836878323 33.4363121677
NOD/ShiLtJ f 33.95 0.3297824259 34.6106335839 33.2893664161
NOD/ShiLtJ m 33.16 0.3612585474 33.8836878323 32.4363121677
NZO/HlLtJ f 34.5 0.4038993348 35.3091075937 33.6908924063
NZO/HlLtJ m 32.975 0.4038993348 33.7841075937 32.1658924063
PWK/PhJ f 35.9 0.3612585474 36.6236878323 35.1763121677
PWK/PhJ m 35.8 0.3612585474 36.5236878323 35.0763121677
WSB/EiJ f 35.0666666667 0.4663827793 36.0009436407 34.1323896926
WSB/EiJ m 36.1 0.4038993348 36.9091075937 35.2908924063


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 34.05 0.2554483687 34.5617245736 33.5382754264
A/J both 34.52 0.2554483687 35.0317245736 34.0082754264
C57BL/6J both 32.925 0.3497870845 33.6257077305 32.2242922695
DBA/2J both 34.69 0.2554483687 35.2017245736 34.1782754264
NOD/ShiLtJ both 33.555 0.2445731928 34.0449389785 33.0650610215
NZO/HlLtJ both 33.7375 0.2855999585 34.3096254662 33.1653745338
PWK/PhJ both 35.85 0.2554483687 36.3617245736 35.3382754264
WSB/EiJ both 35.5833333333 0.3084832124 36.2012994656 34.9653672011




  GWAS USING LINEAR MIXED MODELS