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Project measure / variable:   Auwerx2   bw_13wks_HFD

ID, description, units MPD:114542   bw_13wks_HFD   body weight at 13 wks of age   [g]  HFD  
Data set, strains Auwerx2   inbred w/CC8   9 strains     sex: both     age: 13wks
Procedure body weight
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  STRAIN COMPARISON PLOT
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Auwerx2 - body weight at 13 wks of age HFD



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested9 strains9 strains
Mean of the strain means26.949   g 32.692   g
Median of the strain means23.123   g 31.79   g
SD of the strain means± 15.34 ± 15.422
Coefficient of variation (CV)0.5692 0.4717
Min–max range of strain means13.134   –   64.39   g 15.738   –   68.53   g
Mean sample size per strain4.4   mice 3.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 546.2853 546.2853 114.6503 < 0.0001
strain 7 3124.3522 446.336 93.6736 < 0.0001
sex:strain 7 159.8907 22.8415 4.7938 0.0003
Residuals 52 247.7695 4.7648


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 23.128 1.2313   5 0.55065 0.0532 21.44, 24.45 -0.25
129S1/SvImJ m 31.79 0.93338   2   0.66 0.0294 31.13, 32.45 -0.06
A/J f 21.37 1.6351   4 0.81756 0.0765 20.19, 23.79 -0.36
A/J m 28.178 1.8607   5 0.83211 0.066 25.36, 30.39 -0.29
C57BL/6J f 23.123 1.1109   3 0.64136 0.048 22.21, 24.36 -0.25
C57BL/6J m 35.053 2.2961   4 1.1481 0.0655 33.32, 38.18 0.15
CAST/EiJ f 13.134 0.759   5 0.33943 0.0578 12.21, 14.01 -0.9
CAST/EiJ m 17.755 0.09192   2   0.065 0.0052 17.69, 17.82 -0.97
DBA/2J f 31.434 3.0536   5 1.3656 0.0971 28.46, 35.76 0.29
DBA/2J m 38.958 2.9784   5 1.332 0.0765 34.98, 43.01 0.41
NOD/ShiLtJ f 29.953 3.4595   6 1.4123 0.1155 26.47, 36.27 0.2
NOD/ShiLtJ m 31.958 1.9889   5 0.88945 0.0622 29.69, 35.14 -0.05
NZO/HlLtJ f 64.39 2.6173   5 1.1705 0.0406 61.98, 68.54 2.44
NZO/HlLtJ m 68.53 0.0   1   0.0 0.0 68.53, 68.53 2.32
PWK/PhJ f 22.497 2.5964   4 1.2982 0.1154 18.86, 24.98 -0.29
PWK/PhJ m 26.27 2.5155   5 1.125 0.0958 22.36, 28.98 -0.42
WSB/EiJ f 13.513 0.38397   3 0.22169 0.0284 13.07, 13.74 -0.88
WSB/EiJ m 15.738 1.0119   5 0.45253 0.0643 14.62, 16.91 -1.1


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 23.128 0.9761965176 25.0868816232 21.1691183768
129S1/SvImJ m 31.79 1.5435022198 34.887263798 28.692736202
A/J f 21.37 1.0914208864 23.5600962347 19.1799037653
A/J m 28.178 0.9761965176 30.1368816232 26.2191183768
C57BL/6J f 23.1233333333 1.2602642851 25.6522386346 20.594428032
C57BL/6J m 35.0525 1.0914208864 37.2425962347 32.8624037653
CAST/EiJ f 13.134 0.9761965176 15.0928816232 11.1751183768
CAST/EiJ m 17.755 1.5435022198 20.852263798 14.657736202
DBA/2J f 31.434 0.9761965176 33.3928816232 29.4751183768
DBA/2J m 38.958 0.9761965176 40.9168816232 36.9991183768
NOD/ShiLtJ f 29.9533333333 0.8911414221 31.7415394209 28.1651272458
NOD/ShiLtJ m 31.958 0.9761965176 33.9168816232 29.9991183768
PWK/PhJ f 22.4975 1.0914208864 24.6875962347 20.3074037653
PWK/PhJ m 26.27 0.9761965176 28.2288816232 24.3111183768
WSB/EiJ f 13.5133333333 1.2602642851 16.0422386346 10.984428032
WSB/EiJ m 15.738 0.9761965176 17.6968816232 13.7791183768


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 27.459 0.9131482278 29.2913659738 25.6266340262
A/J both 24.774 0.7321473882 26.2431612174 23.3048387826
C57BL/6J both 29.0879166667 0.8335864712 30.7606302958 27.4152030376
CAST/EiJ both 15.4445 0.9131482278 17.2768659738 13.6121340262
DBA/2J both 35.196 0.6902751774 36.5811384793 33.8108615207
NOD/ShiLtJ both 30.9556666667 0.6608881666 32.2818357948 29.6294975386
PWK/PhJ both 24.38375 0.7321473882 25.8529112174 22.9145887826
WSB/EiJ both 14.6256666667 0.797061119 16.2250868145 13.0262465189




  GWAS USING LINEAR MIXED MODELS