Project measure / variable:   Schoonjans1   TbMCA_feces_CD

ID, description, units MPD:112790   TbMCA_feces_CD   bile acid tauro-β-muricholic acid amount in feces, at 24 wks   [ng/mL]  CD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   36 strains     sex: m     age: 24wks
Procedure biomarker quantification
Ontology mappings

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  STRAIN COMPARISON PLOT
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Schoonjans1 - bile acid tauro-β-muricholic acid amount in feces, at 24 wks CD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested36 strains
Mean of the strain means2.2788   ng/mL
Median of the strain means1.3244   ng/mL
SD of the strain means± 2.534
Coefficient of variation (CV)1.112
Min–max range of strain means0.3638   –   12.009   ng/mL
Mean sample size per strain4.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 35 1019.5606 29.1303 1.7072 0.0158
Residuals 139 2371.75 17.0629


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 1.4922 0.63859   5 0.28559 0.4279 0.84173, 2.4931 -0.31
BXD100 m 1.8427 0.62136   5 0.27788 0.3372 1.3941, 2.9078 -0.17
BXD11 m 4.4123 1.8568   4 0.92841 0.4208 3.3713, 7.1937 0.84
BXD12 m 1.1622 0.52503   4 0.26251 0.4518 0.81068, 1.9292 -0.44
BXD27 m 6.1435 4.1131   4 2.0566 0.6695 1.5205, 10.654 1.53
BXD32 m 12.009 22.291   4 11.145 1.8562 0.79796, 45.445 3.84
BXD34 m 0.98315 0.39601   4 0.198 0.4028 0.58794, 1.4322 -0.51
BXD39 m 1.5725 0.59354   5 0.26544 0.3775 0.58918, 2.121 -0.28
BXD40 m 0.73725 0.34551   5 0.15452 0.4686 0.49299, 1.329 -0.61
BXD43 m 2.1699 1.8481   4 0.92404 0.8517 0.87782, 4.8837 -0.04
BXD45 m 1.3437 1.1757   3 0.67878 0.875 0.39825, 2.6601 -0.37
BXD48 m 0.61947 0.32844   5 0.14688 0.5302 0.43654, 1.2029 -0.65
BXD48a m 1.5095 0.58977   4 0.29489 0.3907 1.0823, 2.3482 -0.3
BXD49 m 0.54879 0.05828   5 0.02606 0.1062 0.47114, 0.60672 -0.68
BXD51 m 1.2264 0.31295   5 0.13995 0.2552 0.81184, 1.5741 -0.42
BXD53 m 1.0581 0.36252   5 0.16213 0.3426 0.66734, 1.4496 -0.48
BXD55 m 0.6255 0.18225   5 0.08151 0.2914 0.50802, 0.94756 -0.65
BXD6 m 0.91627 0.19365   5 0.08661 0.2114 0.71382, 1.1961 -0.54
BXD62 m 3.516 2.2282   5 0.9965 0.6337 1.6229, 7.2941 0.49
BXD63 m 0.53937 0.15964   5 0.07139 0.296 0.35938, 0.70862 -0.69
BXD64 m 1.4492 0.29645   5 0.13258 0.2046 1.2343, 1.939 -0.33
BXD66 m 2.6502 1.8983   5 0.84896 0.7163 1.0754, 5.7305 0.15
BXD67 m 1.3052 0.25116   4 0.12558 0.1924 1.0659, 1.6446 -0.38
BXD69 m 0.76958 0.26667   5 0.11926 0.3465 0.38061, 1.0227 -0.6
BXD73 m 0.85008 0.53278   5 0.23827 0.6267 0.31721, 1.6792 -0.56
BXD75 m 1.0325 0.65554   5 0.29317 0.6349 0.4235, 2.0469 -0.49
BXD77 m 0.95189 0.46697   5 0.20884 0.4906 0.5264, 1.7001 -0.52
BXD79 m 1.9547 0.87417   5 0.39094 0.4472 1.1698, 3.1334 -0.13
BXD8 m 3.487 2.528   5 1.1306 0.725 1.3156, 7.1242 0.48
BXD81 m 1.1111 0.28745   5 0.12855 0.2587 0.77471, 1.4139 -0.46
BXD84 m 0.79942 0.18557   5 0.08299 0.2321 0.52114, 0.99003 -0.58
BXD87 m 2.1321 0.60219   5 0.26931 0.2824 1.4281, 2.7344 -0.06
BXD89 m 2.986 2.4028   5 1.0746 0.8047 1.5792, 7.2232 0.28
BXD90 m 6.5612 11.285   5 5.0469 1.72 0.93107, 26.704 1.69
C57BL/6J m 0.3638 0.306   10 0.09677 0.8411 0.11297, 1.1939 -0.76
DBA/2J m 9.2037 6.9837   5 3.1232 0.7588 1.1259, 19.76 2.73


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 1.492246 1.8473196602 5.1447252822 -2.1602332822
BXD100 m 1.84266 1.8473196602 5.4951392822 -1.8098192822
BXD11 m 4.41225 2.0653661682 8.4958459807 0.3286540193
BXD12 m 1.1621575 2.0653661682 5.2457534807 -2.9214384807
BXD27 m 6.14345 2.0653661682 10.2270459807 2.0598540193
BXD32 m 12.008685 2.0653661682 16.0922809807 7.9250890193
BXD34 m 0.98315 2.0653661682 5.0667459807 -3.1004459807
BXD39 m 1.572456 1.8473196602 5.2249352822 -2.0800232822
BXD40 m 0.737252 1.8473196602 4.3897312822 -2.9152272822
BXD43 m 2.16988 2.0653661682 6.2534759807 -1.9137159807
BXD45 m 1.3436833333 2.3848794264 6.0590138108 -3.3716471441
BXD48 m 0.619468 1.8473196602 4.2719472822 -3.0330112822
BXD48a m 1.50955 2.0653661682 5.5931459807 -2.5740459807
BXD49 m 0.548786 1.8473196602 4.2012652822 -3.1036932822
BXD51 m 1.226388 1.8473196602 4.8788672822 -2.4260912822
BXD53 m 1.058094 1.8473196602 4.7105732822 -2.5943852822
BXD55 m 0.625504 1.8473196602 4.2779832822 -3.0269752822
BXD6 m 0.91627 1.8473196602 4.5687492822 -2.7362092822
BXD62 m 3.51604 1.8473196602 7.1685192822 -0.1364392822
BXD63 m 0.53937 1.8473196602 4.1918492822 -3.1131092822
BXD64 m 1.44918 1.8473196602 5.1016592822 -2.2032992822
BXD66 m 2.65022 1.8473196602 6.3026992822 -1.0022592822
BXD67 m 1.3052 2.0653661682 5.3887959807 -2.7783959807
BXD69 m 0.769578 1.8473196602 4.4220572822 -2.8829012822
BXD73 m 0.850082 1.8473196602 4.5025612822 -2.8023972822
BXD75 m 1.032474 1.8473196602 4.6849532822 -2.6200052822
BXD77 m 0.951894 1.8473196602 4.6043732822 -2.7005852822
BXD79 m 1.95466 1.8473196602 5.6071392822 -1.6978192822
BXD8 m 3.48698 1.8473196602 7.1394592822 -0.1654992822
BXD81 m 1.111094 1.8473196602 4.7635732822 -2.5413852822
BXD84 m 0.799422 1.8473196602 4.4519012822 -2.8530572822
BXD87 m 2.13214 1.8473196602 5.7846192822 -1.5203392822
BXD89 m 2.98598 1.8473196602 6.6384592822 -0.6664992822
BXD90 m 6.561214 1.8473196602 10.2136932822 2.9087347178
C57BL/6J m 0.363804 1.3062522588 2.9464968686 -2.2188888686
DBA/2J m 9.2037 1.8473196602 12.8561792822 5.5512207178




  GWAS USING LINEAR MIXED MODELS