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Project measure / variable:   Schoonjans1   CA_plasma_t60_CD

ID, description, units MPD:112726   CA_plasma_t60_CD   plasma bile acid cholic acid amount, glucose kinetic test, at 20 wks of age, after 60 min   [ng/mL]  CD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   36 strains     sex: m     age: 20wks
Procedure biomarker quantification
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  STRAIN COMPARISON PLOT
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Schoonjans1 - plasma bile acid cholic acid amount, glucose kinetic test, at 20 wks of age, after 60 min CD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested36 strains
Mean of the strain means37.015   ng/mL
Median of the strain means11.791   ng/mL
SD of the strain means± 51.78
Coefficient of variation (CV)1.3988
Min–max range of strain means0.7548   –   202.4   ng/mL
Mean sample size per strain4.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 35 457473.2999 13070.6657 2.7407 < 0.0001
Residuals 128 610448.6416 4769.13


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 21.194 41.578   5 18.594 1.9618 1.012, 95.52 -0.31
BXD100 m 5.066 2.5868   5 1.1569 0.5106 2.174, 9.026 -0.62
BXD11 m 1.1355 1.1376   4 0.56881 1.0019 0.232, 2.8 -0.69
BXD12 m 49.864 60.94   3 35.186 1.2222 4.34, 119.1 0.25
BXD27 m 13.779 8.9848   4 4.4924 0.6521 4.3136, 25.598 -0.45
BXD32 m 137.4 144.9   5 64.81 1.0547 15.556, 374.9 1.94
BXD34 m 32.029 20.051   5 8.967 0.626 12.88, 62.18 -0.1
BXD39 m 7.4353 7.7374   3 4.4672 1.0406 2.694, 16.364 -0.57
BXD40 m 77.35 73.2   4 36.599 0.9463 14.096, 183.0 0.78
BXD43 m 3.9203 5.0729   6 2.071 1.294 0.506, 14.116 -0.64
BXD45 m 21.888 39.146   4 19.573 1.7885 1.422, 80.59 -0.29
BXD48 m 13.35 9.5729   5 4.2811 0.7171 4.808, 26.818 -0.46
BXD48a m 33.956 22.274   4 11.137 0.656 5.59, 58.57 -0.06
BXD49 m 98.23 115.8   5 51.78 1.1787 8.668, 298.8 1.18
BXD51 m 5.3848 3.7117   5 1.6599 0.6893 1.01, 9.5 -0.61
BXD53 m 2.2555 2.1156   4 1.0578 0.938 0.518, 4.858 -0.67
BXD55 m 74.93 62.5   5 27.951 0.8341 15.084, 178.4 0.73
BXD6 m 202.4 190.1   5 85.02 0.9391 56.43, 521.5 3.19
BXD62 m 7.5096 4.4492   5 1.9897 0.5925 2.794, 14.326 -0.57
BXD63 m 5.645 3.032   4 1.516 0.5371 2.986, 8.77 -0.61
BXD64 m 0.7548 0.48117   5 0.21518 0.6375 0.05, 1.326 -0.7
BXD66 m 3.306 0.84586   5 0.37828 0.2559 2.396, 4.51 -0.65
BXD67 m 0.97867 1.0536   3 0.60828 1.0765 0.036, 2.116 -0.7
BXD69 m 21.763 26.937   5 12.046 1.2377 6.124, 69.78 -0.29
BXD73 m 37.584 32.859   4 16.429 0.8743 12.178, 84.55 0.01
BXD75 m 10.233 11.189   5 5.0038 1.0934 1.9, 29.07 -0.52
BXD77 m 130.0 141.1   5 63.09 1.0852 18.774, 316.0 1.8
BXD79 m 10.019 7.5173   5 3.3618 0.7503 2.794, 20.808 -0.52
BXD8 m 4.4164 6.9248   5 3.0969 1.568 0.142, 16.678 -0.63
BXD81 m 19.137 15.909   3 9.1851 0.8313 4.014, 35.73 -0.35
BXD84 m 1.1612 0.9407   5 0.42069 0.8101 0.276, 2.754 -0.69
BXD87 m 103.0 81.84   5 36.599 0.7947 41.672, 244.1 1.27
BXD89 m 6.44 7.6839   5 3.4363 1.1931 0.162, 15.454 -0.59
BXD90 m 6.1904 7.5258   5 3.3657 1.2157 0.57, 15.186 -0.6
C57BL/6J m 160.6 199.4   5 89.17 1.2417 17.348, 505.9 2.39
DBA/2J m 2.2515 1.4343   4 0.71713 0.637 0.472, 3.914 -0.67


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 21.1936 30.8840736058 82.3030161681 -39.9158161681
BXD100 m 5.066 30.8840736058 66.1754161681 -56.0434161681
BXD11 m 1.1355 34.5294440024 69.4579043086 -67.1869043086
BXD12 m 49.864 39.8711675795 128.7559170385 -29.0279170385
BXD27 m 13.7789 34.5294440024 82.1013043086 -54.5435043086
BXD32 m 137.4064 30.8840736058 198.5158161681 76.2969838319
BXD34 m 32.0292 30.8840736058 93.1386161681 -29.0802161681
BXD39 m 7.4353333333 39.8711675795 86.3272503718 -71.4565837051
BXD40 m 77.3515 34.5294440024 145.6739043086 9.0290956914
BXD43 m 3.9203333333 28.1931729693 59.7053428521 -51.8646761854
BXD45 m 21.888 34.5294440024 90.2104043086 -46.4344043086
BXD48 m 13.35 30.8840736058 74.4594161681 -47.7594161681
BXD48a m 33.9555 34.5294440024 102.2779043086 -34.3669043086
BXD49 m 98.2316 30.8840736058 159.3410161681 37.1221838319
BXD51 m 5.3848 30.8840736058 66.4942161681 -55.7246161681
BXD53 m 2.2555 34.5294440024 70.5779043086 -66.0669043086
BXD55 m 74.93 30.8840736058 136.0394161681 13.8205838319
BXD6 m 202.446 30.8840736058 263.5554161681 141.3365838319
BXD62 m 7.5096 30.8840736058 68.6190161681 -53.5998161681
BXD63 m 5.645 34.5294440024 73.9674043086 -62.6774043086
BXD64 m 0.7548 30.8840736058 61.8642161681 -60.3546161681
BXD66 m 3.306 30.8840736058 64.4154161681 -57.8034161681
BXD67 m 0.9786666667 39.8711675795 79.8705837051 -77.9132503718
BXD69 m 21.7632 30.8840736058 82.8726161681 -39.3462161681
BXD73 m 37.5835 34.5294440024 105.9059043086 -30.7389043086
BXD75 m 10.2332 30.8840736058 71.3426161681 -50.8762161681
BXD77 m 129.9864 30.8840736058 191.0958161681 68.8769838319
BXD79 m 10.0188 30.8840736058 71.1282161681 -51.0906161681
BXD8 m 4.4164 30.8840736058 65.5258161681 -56.6930161681
BXD81 m 19.1366666667 39.8711675795 98.0285837051 -59.7552503718
BXD84 m 1.1612 30.8840736058 62.2706161681 -59.9482161681
BXD87 m 102.9844 30.8840736058 164.0938161681 41.8749838319
BXD89 m 6.44 30.8840736058 67.5494161681 -54.6694161681
BXD90 m 6.1904 30.8840736058 67.2998161681 -54.9190161681
C57BL/6J m 160.5772 30.8840736058 221.6866161681 99.4677838319
DBA/2J m 2.2515 34.5294440024 70.5739043086 -66.0709043086




  GWAS USING LINEAR MIXED MODELS