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Project measure / variable:   Schoonjans1   TCDCA_plasma_t0_CD

ID, description, units MPD:112670   TCDCA_plasma_t0_CD   plasma bile acid taurochenodeoxycholic acid amount, glucose kinetic test, at 20 wks of age, at 0 min   [ng/mL]  CD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   36 strains     sex: m     age: 20wks
Procedure biomarker quantification
Ontology mappings

  STRAIN COMPARISON PLOT
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Schoonjans1 - plasma bile acid taurochenodeoxycholic acid amount, glucose kinetic test, at 20 wks of age, at 0 min CD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested36 strains
Mean of the strain means13.121   ng/mL
Median of the strain means10.925   ng/mL
SD of the strain means± 9.0648
Coefficient of variation (CV)0.6909
Min–max range of strain means3.6933   –   52.41   ng/mL
Mean sample size per strain4.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 35 14075.4098 402.1546 3.1356 < 0.0001
Residuals 131 16801.1557 128.2531


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 3.6933 1.3813   5 0.61775 0.374 2.156, 5.2765 -1.04
BXD100 m 10.544 2.6457   5 1.1832 0.2509 8.814, 15.192 -0.28
BXD11 m 13.039 8.3521   4 4.1761 0.6406 3.82, 23.206 -0.01
BXD12 m 9.502 7.0714   3 4.0827 0.7442 4.086, 17.502 -0.4
BXD27 m 24.396 18.675   4 9.3376 0.7655 13.546, 52.36 1.24
BXD32 m 8.8144 6.8106   5 3.0458 0.7727 4.332, 20.862 -0.48
BXD34 m 15.965 8.7974   5 3.9343 0.551 5.508, 24.772 0.31
BXD39 m 9.0807 1.1178   3 0.64537 0.1231 8.384, 10.37 -0.45
BXD40 m 9.598 4.3912   4 2.1956 0.4575 5.932, 15.968 -0.39
BXD43 m 5.0354 3.679   7 1.3905 0.7306 0.98, 11.04 -0.89
BXD45 m 16.934 9.236   4 4.618 0.5454 7.892, 29.506 0.42
BXD48 m 9.4736 5.9191   5 2.6471 0.6248 4.028, 16.956 -0.4
BXD48a m 8.941 1.6408   4 0.82041 0.1835 7.402, 11.256 -0.46
BXD49 m 9.9732 2.1957   5 0.98195 0.2202 7.55, 12.724 -0.35
BXD51 m 10.474 5.3623   5 2.3981 0.512 3.448, 17.54 -0.29
BXD53 m 12.641 11.533   4 5.7663 0.9123 5.186, 29.84 -0.05
BXD55 m 4.3452 0.97467   5 0.43589 0.2243 2.892, 5.33 -0.97
BXD6 m 13.64 8.3491   5 3.7338 0.6121 6.134, 26.892 0.06
BXD62 m 16.945 8.0617   5 3.6053 0.4758 10.582, 27.844 0.42
BXD63 m 5.468 2.0439   4 1.022 0.3738 3.024, 7.452 -0.84
BXD64 m 29.839 19.03   5 8.5105 0.6378 9.294, 56.61 1.84
BXD66 m 11.929 7.0682   5 3.161 0.5925 7.376, 24.414 -0.13
BXD67 m 4.36 5.8646   4 2.9323 1.3451 0.25, 12.918 -0.97
BXD69 m 15.049 8.0573   5 3.6033 0.5354 5.744, 22.126 0.21
BXD73 m 6.152 5.4093   4 2.7046 0.8793 1.298, 13.216 -0.77
BXD75 m 52.41 43.515   5 19.461 0.8302 10.13, 123.6 4.33
BXD77 m 16.35 9.5171   5 4.2562 0.5821 4.438, 29.544 0.36
BXD79 m 14.385 1.9849   5 0.88767 0.138 12.168, 16.47 0.14
BXD8 m 21.154 14.912   5 6.669 0.7049 1.116, 40.924 0.89
BXD81 m 4.8619 3.2038   3 1.8497 0.659 2.8361, 8.5556 -0.91
BXD84 m 11.307 5.211   5 2.3304 0.4609 2.558, 15.2 -0.2
BXD87 m 13.174 2.418   5 1.0814 0.1835 8.954, 14.832 0.01
BXD89 m 24.351 19.864   6 8.1093 0.8157 7.314, 61.5 1.24
BXD90 m 9.5344 4.5171   5 2.0201 0.4738 3.29, 14.86 -0.4
C57BL/6J m 5.042 1.537   5 0.68735 0.3048 3.49, 7.246 -0.89
DBA/2J m 13.939 6.412   4 3.206 0.46 7.936, 19.768 0.09


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 3.6933 5.0646440575 13.7123740621 -6.3257740621
BXD100 m 10.5444 5.0646440575 20.5634740621 0.5253259379
BXD11 m 13.039 5.6624441972 24.2406653372 1.8373346628
BXD12 m 9.502 6.5384273631 22.4365689956 -3.4325689956
BXD27 m 24.396 5.6624441972 35.5976653372 13.1943346628
BXD32 m 8.8144 5.0646440575 18.8334740621 -1.2046740621
BXD34 m 15.9652 5.0646440575 25.9842740621 5.9461259379
BXD39 m 9.0806666667 6.5384273631 22.0152356623 -3.853902329
BXD40 m 9.598 5.6624441972 20.7996653372 -1.6036653372
BXD43 m 5.0354285714 4.2804054739 13.5030916434 -3.4322345006
BXD45 m 16.934 5.6624441972 28.1356653372 5.7323346628
BXD48 m 9.4736 5.0646440575 19.4926740621 -0.5454740621
BXD48a m 8.941 5.6624441972 20.1426653372 -2.2606653372
BXD49 m 9.9732 5.0646440575 19.9922740621 -0.0458740621
BXD51 m 10.474 5.0646440575 20.4930740621 0.4549259379
BXD53 m 12.6415 5.6624441972 23.8431653372 1.4398346628
BXD55 m 4.3452 5.0646440575 14.3642740621 -5.6738740621
BXD6 m 13.6396 5.0646440575 23.6586740621 3.6205259379
BXD62 m 16.9448 5.0646440575 26.9638740621 6.9257259379
BXD63 m 5.468 5.6624441972 16.6696653372 -5.7336653372
BXD64 m 29.8388 5.0646440575 39.8578740621 19.8197259379
BXD66 m 11.9288 5.0646440575 21.9478740621 1.9097259379
BXD67 m 4.36 5.6624441972 15.5616653372 -6.8416653372
BXD69 m 15.0492 5.0646440575 25.0682740621 5.0301259379
BXD73 m 6.152 5.6624441972 17.3536653372 -5.0496653372
BXD75 m 52.4128 5.0646440575 62.4318740621 42.3937259379
BXD77 m 16.3496 5.0646440575 26.3686740621 6.3305259379
BXD79 m 14.3852 5.0646440575 24.4042740621 4.3661259379
BXD8 m 21.1544 5.0646440575 31.1734740621 11.1353259379
BXD81 m 4.8619 6.5384273631 17.7964689956 -8.0726689956
BXD84 m 11.3072 5.0646440575 21.3262740621 1.2881259379
BXD87 m 13.174 5.0646440575 23.1930740621 3.1549259379
BXD89 m 24.351 4.6233663267 33.4971214485 15.2048785515
BXD90 m 9.5344 5.0646440575 19.5534740621 -0.4846740621
C57BL/6J m 5.042 5.0646440575 15.0610740621 -4.9770740621
DBA/2J m 13.9385 5.6624441972 25.1401653372 2.7368346628




  GWAS USING LINEAR MIXED MODELS