Project measure / variable:   Noll1   IgG2ac_d45

ID, description, units MPD:112616   IgG2ac_d45   immunoglobulin G2a plus G2c (serum IgG2a pooled with IgG2c) area under curve (AUC) post-infection   [AUC]  day 45  
influenza A (H1N1) virus study
Data set, strains Noll1   CC RIX   35 strains     sex: f     age: 8-12 wks
Procedure immunoglobulin quantification
Ontology mappings

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  STRAIN COMPARISON PLOT
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Noll1 - immunoglobulin G2a plus G2c (serum IgG2a pooled with IgG2c) area under curve (AUC) post-infection day 45



  MEASURE SUMMARY
Measure Summary Female
Number of strains tested35 strains
Mean of the strain means8.3895   AUC
Median of the strain means8.7007   AUC
SD of the strain means± 1.7336
Coefficient of variation (CV)0.2066
Min–max range of strain means2.1814   –   10.711   AUC
Mean sample size per strain3.2   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 29 332.7163 11.473 14.4761 < 0.0001
Residuals 77 61.0261 0.7925


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
RIX:CC(002 x 021) f 5.5444 1.2772   3 0.73737 0.2304 4.4589, 6.9517 -1.64
RIX:CC(003 x 051) f 9.3922 0.84569   3 0.48826 0.09 8.4822, 10.154 0.58
RIX:CC(003 x 062) f 10.423 0.61551   8 0.21761 0.0591 9.3934, 11.213 1.17
RIX:CC(005 x 038) f 7.5385 0.71793   3 0.41449 0.0952 6.7147, 8.0304 -0.49
RIX:CC(007 x 075) f 8.3277 0.0   1   0.0 0.0 8.3277, 8.3277 -0.04
RIX:CC(013 x 026) f 7.1799 0.27111   3 0.15652 0.0378 6.8762, 7.3975 -0.7
RIX:CC(013 x 041) f 6.3299 1.7737   6 0.72411 0.2802 2.9279, 8.0103 -1.19
RIX:CC(015 x 018) f 9.6092 0.04094   2   0.02895 0.0043 9.5803, 9.6382 0.7
RIX:CC(015 x 059) f 8.5449 0.0   1   0.0 0.0 8.5449, 8.5449 0.09
RIX:CC(016 x 038) f 10.433 0.7384   6 0.30145 0.0708 8.9842, 11.081 1.18
RIX:CC(017 x 041) f 9.5654 0.41277   3 0.23832 0.0432 9.1137, 9.923 0.68
RIX:CC(018 x 009) f 10.455 0.54233   6 0.2214 0.0519 9.5451, 10.963 1.19
RIX:CC(018 x 065) f 9.3773 0.32878   3 0.18982 0.0351 9.1531, 9.7547 0.57
RIX:CC(019 x 002) f 10.257 0.58218   4 0.29109 0.0568 9.4338, 10.7 1.08
RIX:CC(025 x 028) f 9.249 0.9402   3 0.54283 0.1017 8.1864, 9.9731 0.5
RIX:CC(026 x 034) f 8.3783 0.31443   4 0.15722 0.0375 8.162, 8.8455 -0.01
RIX:CC(028 x 030) f 9.9134 1.1058   4 0.55291 0.1115 8.4559, 10.775 0.88
RIX:CC(032 x 017) f 6.926 2.9025   3 1.6757 0.4191 3.5779, 8.73 -0.84
RIX:CC(034 x 016) f 7.6392 0.48518   4 0.24259 0.0635 7.277, 8.3234 -0.43
RIX:CC(035 x 020) f 9.0621 0.0   1   0.0 0.0 9.0621, 9.0621 0.39
RIX:CC(035 x 071) f 2.1814 0.0413   2   0.0292 0.0189 2.1522, 2.2106 -3.58
RIX:CC(037 x 057) f 7.8608 0.0   1   0.0 0.0 7.8608, 7.8608 -0.31
RIX:CC(038 x 013) f 8.9957 0.67317   2   0.476 0.0748 8.5197, 9.4717 0.35
RIX:CC(041 x 016) f 7.9021 0.3194   4 0.1597 0.0404 7.6336, 8.3639 -0.28
RIX:CC(042 x 017) f 10.711 0.24776   5 0.1108 0.0231 10.44, 11.114 1.34
RIX:CC(042 x 019) f 8.9494 0.95135   3 0.54926 0.1063 8.006, 9.9085 0.32
RIX:CC(043 x 037) f 9.3361 0.18724   2   0.1324 0.0201 9.2037, 9.4685 0.55
RIX:CC(051 x 005) f 7.4875 0.47395   3 0.27363 0.0633 6.994, 7.9391 -0.52
RIX:CC(051 x 009) f 8.117 1.2706   3 0.73358 0.1565 6.6638, 9.0183 -0.16
RIX:CC(057 x 052) f 9.6842 0.56225   4 0.28112 0.0581 8.8856, 10.117 0.75
RIX:CC(062 x 046) f 5.4917 0.2214   3 0.12782 0.0403 5.2362, 5.627 -1.67
RIX:CC(063 x 002) f 9.2839 0.12219   3 0.07055 0.0132 9.2098, 9.4249 0.52
RIX:CC(074 x 062) f 8.7007 0.26142   2   0.18485 0.03 8.5159, 8.8856 0.18
RIX:CC(075 x 021) f 7.9549 0.0   1   0.0 0.0 7.9549, 7.9549 -0.25
RIX:CC(075 x 035) f 6.8324 0.13965   3 0.08062 0.0204 6.6719, 6.9261 -0.9


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
RIX:CC(002 x 021) f 5.5444333333 0.5139864452 6.5679111015 4.5209555651
RIX:CC(003 x 051) f 9.3921666667 0.5139864452 10.4156444349 8.3686888985
RIX:CC(003 x 062) f 10.423125 0.3147511314 11.0498745738 9.7963754262
RIX:CC(005 x 038) f 7.5385333333 0.5139864452 8.5620111015 6.5150555651
RIX:CC(013 x 026) f 7.1799 0.5139864452 8.2033777682 6.1564222318
RIX:CC(013 x 041) f 6.3299 0.3634433009 7.0536080703 5.6061919297
RIX:CC(015 x 018) f 9.60925 0.6295022627 10.8627491476 8.3557508524
RIX:CC(016 x 038) f 10.4325333333 0.3634433009 11.1562414036 9.708825263
RIX:CC(017 x 041) f 9.5654 0.5139864452 10.5888777682 8.5419222318
RIX:CC(018 x 009) f 10.4550166667 0.3634433009 11.178724737 9.7313085964
RIX:CC(018 x 065) f 9.3772666667 0.5139864452 10.4007444349 8.3537888985
RIX:CC(019 x 002) f 10.25695 0.4451253188 11.1433077475 9.3705922525
RIX:CC(025 x 028) f 9.2489666667 0.5139864452 10.2724444349 8.2254888985
RIX:CC(026 x 034) f 8.378325 0.4451253188 9.2646827475 7.4919672525
RIX:CC(028 x 030) f 9.91335 0.4451253188 10.7997077475 9.0269922525
RIX:CC(032 x 017) f 6.9260333333 0.5139864452 7.9495111015 5.9025555651
RIX:CC(034 x 016) f 7.639175 0.4451253188 8.5255327475 6.7528172525
RIX:CC(035 x 071) f 2.1814 0.6295022627 3.4348991476 0.9279008524
RIX:CC(038 x 013) f 8.9957 0.6295022627 10.2491991476 7.7422008524
RIX:CC(041 x 016) f 7.9021 0.4451253188 8.7884577475 7.0157422525
RIX:CC(042 x 017) f 10.7114 0.3981321885 11.5041824703 9.9186175297
RIX:CC(042 x 019) f 8.9494333333 0.5139864452 9.9729111015 7.9259555651
RIX:CC(043 x 037) f 9.3361 0.6295022627 10.5895991476 8.0826008524
RIX:CC(051 x 005) f 7.4875333333 0.5139864452 8.5110111015 6.4640555651
RIX:CC(051 x 009) f 8.1170333333 0.5139864452 9.1405111015 7.0935555651
RIX:CC(057 x 052) f 9.684225 0.4451253188 10.5705827475 8.7978672525
RIX:CC(062 x 046) f 5.4917 0.5139864452 6.5151777682 4.4682222318
RIX:CC(063 x 002) f 9.2838666667 0.5139864452 10.3073444349 8.2603888985
RIX:CC(074 x 062) f 8.70075 0.6295022627 9.9542491476 7.4472508524
RIX:CC(075 x 035) f 6.8324 0.5139864452 7.8558777682 5.8089222318




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA