Project measure / variable:   Auwerx1   ogtt_ins_t0_HFD

ID, description, units MPD:111265   ogtt_ins_t0_HFD   insulin baseline, glucose tolerance test (pregavage, overnight fast)   [µg/L]  HFD  
high-fat diet study
Data set, strains Auwerx1   BXD w/par   56 strains     sex: m     age: 17wks
Procedure hormone quantification
Ontology mappings

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  STRAIN COMPARISON PLOT
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Auwerx1 - insulin baseline, glucose tolerance test (pregavage, overnight fast) HFD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested56 strains
Mean of the strain means2.0222   µg/L
Median of the strain means1.6069   µg/L
SD of the strain means± 1.6468
Coefficient of variation (CV)0.8144
Min–max range of strain means0.02   –   9.7933   µg/L
Mean sample size per strain4.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 52 489.0593 9.405 8.1959 < 0.0001
Residuals 169 193.9306 1.1475


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 0.354 0.10479   5 0.04686 0.296 0.24, 0.5 -1.01
BXD100 m 2.561 1.4684   5 0.65669 0.5734 0.762, 4.789 0.33
BXD101 m 0.9775 0.19805   4 0.09903 0.2026 0.74, 1.16 -0.63
BXD11 m 1.0173 0.87725   3 0.50648 0.8623 0.34114, 2.0086 -0.61
BXD12 m 0.1498 0.13885   5 0.06209 0.9269 0.07, 0.396 -1.14
BXD16 m 1.5165 0.92226   5 0.41245 0.6081 0.41411, 2.8191 -0.31
BXD2 m 1.6463 0.72586   5 0.32461 0.4409 0.80753, 2.6076 -0.23
BXD27 m 4.4319 2.0645   4 1.0322 0.4658 2.6889, 7.202 1.46
BXD32 m 1.72 0.6603   4 0.33015 0.3839 1.1, 2.48 -0.18
BXD34 m 0.38802 0.46709   2   0.33028 1.2038 0.05774, 0.7183 -0.99
BXD39 m 3.0303 1.3932   5 0.62305 0.4598 1.6148, 5.062 0.61
BXD40 m 0.08 0.0   1   0.0 0.0 0.08, 0.08 -1.18
BXD43 m 0.02 0.0   1   0.0 0.0 0.02, 0.02 -1.22
BXD44 m 2.8629 1.4157   9 0.4719 0.4945 1.043, 4.558 0.51
BXD45 m 2.114 0.68277   4 0.34139 0.323 1.592, 3.113 0.06
BXD48 m 1.4183 0.44415   3 0.25643 0.3132 1.037, 1.906 -0.37
BXD48a m 9.7933 3.2458   3 1.874 0.3314 6.047, 11.761 4.72
BXD49 m 0.9085 0.65549   2   0.4635 0.7215 0.445, 1.372 -0.68
BXD50 m 1.8964 0.94111   5 0.42088 0.4963 0.68, 3.14 -0.08
BXD51 m 1.8715 0.45447   4 0.22724 0.2428 1.474, 2.524 -0.09
BXD53 m 0.83511 0.35673   5 0.15953 0.4272 0.23996, 1.1366 -0.72
BXD55 m 1.1917 0.2962   4 0.1481 0.2485 0.781, 1.478 -0.5
BXD56 m 0.729 0.25412   4 0.12706 0.3486 0.502, 1.088 -0.79
BXD6 m 0.8025 0.33762   4 0.16881 0.4207 0.32026, 1.0369 -0.74
BXD60 m 3.458 0.67618   5 0.3024 0.1955 2.44, 4.22 0.87
BXD61 m 4.805 2.1587   5 0.9654 0.4493 3.118, 8.258 1.69
BXD62 m 1.5675 0.24722   4 0.12361 0.1577 1.32, 1.823 -0.28
BXD63 m 2.4588 0.74123   4 0.37061 0.3015 1.569, 3.354 0.27
BXD64 m 1.0483 0.11053   3 0.06381 0.1054 0.926, 1.141 -0.59
BXD65 m 4.3465 0.49568   2   0.3505 0.114 3.996, 4.697 1.41
BXD65a m 2.2745 0.78654   4 0.39327 0.3458 1.597, 3.191 0.15
BXD66 m 4.175 1.8931   4 0.94653 0.4534 1.681, 5.962 1.31
BXD67 m 0.50828 0.36554   5 0.16348 0.7192 0.23696, 1.1359 -0.92
BXD68 m 0.195 0.24466   2   0.173 1.2547 0.022, 0.368 -1.11
BXD69 m 1.7327 0.5   3 0.28868 0.2886 1.264, 2.259 -0.18
BXD70 m 1.3233 0.34645   4 0.17322 0.2618 0.84, 1.608 -0.42
BXD71 m 3.32 0.61563   4 0.30781 0.1854 2.88, 4.2 0.79
BXD73 m 1.3462 0.85522   5 0.38247 0.6353 0.359, 2.423 -0.41
BXD73a m 4.743 2.9077   4 1.4539 0.6131 2.426, 8.971 1.65
BXD73b m 1.2394 0.66262   5 0.29633 0.5346 0.552, 2.273 -0.48
BXD75 m 2.4586 0.38363   5 0.17156 0.156 1.83, 2.759 0.27
BXD77 m 2.548 1.555   5 0.69539 0.6103 0.58, 4.75 0.32
BXD79 m 0.9712 0.55143   5 0.24661 0.5678 0.471, 1.9 -0.64
BXD8 m 0.05714 0.0   1   0.0 0.0 0.05714, 0.05714 -1.19
BXD81 m 2.7227 0.32846   4 0.16423 0.1206 2.274, 3.017 0.43
BXD83 m 3.8298 2.0657   4 1.0329 0.5394 1.059, 6.038 1.1
BXD84 m 2.1047 0.17172   3 0.09914 0.0816 1.959, 2.294 0.05
BXD85 m 2.277 0.45147   4 0.22573 0.1983 1.823, 2.682 0.15
BXD87 m 2.0186 0.65233   5 0.29173 0.3232 1.082, 2.688 0.0
BXD89 m 1.401 1.3268   4 0.66342 0.9471 0.224, 3.297 -0.38
BXD90 m 1.188 0.75663   4 0.37831 0.6369 0.09, 1.8 -0.51
BXD95 m 1.4375 0.30159   4 0.1508 0.2098 1.11, 1.84 -0.36
BXD98 m 1.39 0.21201   5 0.09482 0.1525 1.11, 1.66 -0.38
BXD99 m 0.8936 0.19482   5 0.08713 0.218 0.68, 1.124 -0.69
C57BL/6J m 3.3007 0.65032   4 0.32516 0.197 2.526, 3.893 0.78
DBA/2J m 3.7855 1.5794   4 0.78969 0.4172 2.756, 6.14 1.07


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 0.354 0.4790653879 1.2997231965 -0.5917231965
BXD100 m 2.561 0.4790653879 3.5067231965 1.6152768035
BXD101 m 0.9775 0.5356113865 2.0348506777 -0.0798506777
BXD11 m 1.0173233333 0.6184707563 2.2382467301 -0.2036000634
BXD12 m 0.1498 0.4790653879 1.0955231965 -0.7959231965
BXD16 m 1.516502 0.4790653879 2.4622251965 0.5707788035
BXD2 m 1.646286 0.4790653879 2.5920091965 0.7005628035
BXD27 m 4.431925 0.5356113865 5.4892756777 3.3745743223
BXD32 m 1.72 0.5356113865 2.7773506777 0.6626493223
BXD34 m 0.38802 0.7574688869 1.8833396685 -1.1072996685
BXD39 m 3.03026 0.4790653879 3.9759831965 2.0845368035
BXD44 m 2.8628888889 0.3570742576 3.5677893407 2.1579884371
BXD45 m 2.114 0.5356113865 3.1713506777 1.0566493223
BXD48 m 1.4183333333 0.6184707563 2.6392567301 0.1974099366
BXD48a m 9.7933333333 0.6184707563 11.0142567301 8.5724099366
BXD49 m 0.9085 0.7574688869 2.4038196685 -0.5868196685
BXD50 m 1.8964 0.4790653879 2.8421231965 0.9506768035
BXD51 m 1.8715 0.5356113865 2.9288506777 0.8141493223
BXD53 m 0.835108 0.4790653879 1.7808311965 -0.1106151965
BXD55 m 1.19175 0.5356113865 2.2491006777 0.1343993223
BXD56 m 0.729 0.5356113865 1.7863506777 -0.3283506777
BXD6 m 0.8025 0.5356113865 1.8598506777 -0.2548506777
BXD60 m 3.458 0.4790653879 4.4037231965 2.5122768035
BXD61 m 4.805 0.4790653879 5.7507231965 3.8592768035
BXD62 m 1.5675 0.5356113865 2.6248506777 0.5101493223
BXD63 m 2.45875 0.5356113865 3.5161006777 1.4013993223
BXD64 m 1.0483333333 0.6184707563 2.2692567301 -0.1725900634
BXD65 m 4.3465 0.7574688869 5.8418196685 2.8511803315
BXD65a m 2.2745 0.5356113865 3.3318506777 1.2171493223
BXD66 m 4.175 0.5356113865 5.2323506777 3.1176493223
BXD67 m 0.508282 0.4790653879 1.4540051965 -0.4374411965
BXD68 m 0.195 0.7574688869 1.6903196685 -1.3003196685
BXD69 m 1.7326666667 0.6184707563 2.9535900634 0.5117432699
BXD70 m 1.32325 0.5356113865 2.3806006777 0.2658993223
BXD71 m 3.32 0.5356113865 4.3773506777 2.2626493223
BXD73 m 1.3462 0.4790653879 2.2919231965 0.4004768035
BXD73a m 4.743 0.5356113865 5.8003506777 3.6856493223
BXD73b m 1.2394 0.4790653879 2.1851231965 0.2936768035
BXD75 m 2.4586 0.4790653879 3.4043231965 1.5128768035
BXD77 m 2.548 0.4790653879 3.4937231965 1.6022768035
BXD79 m 0.9712 0.4790653879 1.9169231965 0.0254768035
BXD81 m 2.72275 0.5356113865 3.7801006777 1.6653993223
BXD83 m 3.82975 0.5356113865 4.8871006777 2.7723993223
BXD84 m 2.1046666667 0.6184707563 3.3255900634 0.8837432699
BXD85 m 2.277 0.5356113865 3.3343506777 1.2196493223
BXD87 m 2.0186 0.4790653879 2.9643231965 1.0728768035
BXD89 m 1.401 0.5356113865 2.4583506777 0.3436493223
BXD90 m 1.188 0.5356113865 2.2453506777 0.1306493223
BXD95 m 1.4375 0.5356113865 2.4948506777 0.3801493223
BXD98 m 1.39 0.4790653879 2.3357231965 0.4442768035
BXD99 m 0.8936 0.4790653879 1.8393231965 -0.0521231965
C57BL/6J m 3.30075 0.5356113865 4.3581006777 2.2433993223
DBA/2J m 3.7855 0.5356113865 4.8428506777 2.7281493223




  GWAS USING LINEAR MIXED MODELS