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Project measure / variable:   Auwerx1   ogtt_gluc_t45_HFD

ID, description, units MPD:111251   ogtt_gluc_t45_HFD   glucose, glucose tolerance test (20% glucose oral gavage, overnight fast), after 45 min   [mg/dL]  HFD  
high-fat diet study
Data set, strains Auwerx1   BXD w/par   56 strains     sex: m     age: 17wks
Procedure glucose tolerance
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  STRAIN COMPARISON PLOT
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Auwerx1 - glucose, glucose tolerance test (20% glucose oral gavage, overnight fast), after 45 min HFD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested56 strains
Mean of the strain means396.3   mg/dL
Median of the strain means380.8   mg/dL
SD of the strain means± 104.7
Coefficient of variation (CV)0.2643
Min–max range of strain means223.7   –   600.0   mg/dL
Mean sample size per strain4.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 55 2780962.5371 50562.9552 9.7655 < 0.0001
Residuals 192 994119.85 5177.7076


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 398.2 37.996   5 16.992 0.0954 340.0, 438.0 0.02
BXD100 m 381.4 87.58   5 39.167 0.2296 303.0, 483.0 -0.14
BXD101 m 300.0 46.44   4 23.22 0.1548 237.0, 349.0 -0.92
BXD11 m 329.4 90.64   5 40.536 0.2752 204.0, 434.0 -0.64
BXD12 m 271.6 72.36   5 32.36 0.2664 191.0, 378.0 -1.19
BXD16 m 544.4 77.85   5 34.816 0.143 438.0, 600.0 1.41
BXD2 m 240.8 29.038   5 12.986 0.1206 199.0, 281.0 -1.48
BXD27 m 553.2 35.976   4 17.988 0.065 516.0, 600.0 1.5
BXD32 m 368.3 140.2   3 80.96 0.3807 240.0, 518.0 -0.27
BXD34 m 338.6 88.75   5 39.691 0.2621 191.0, 410.0 -0.55
BXD39 m 540.2 42.541   5 19.025 0.0787 482.0, 600.0 1.37
BXD40 m 418.0 19.916   4 9.9582 0.0476 399.0, 446.0 0.21
BXD43 m 492.0 24.88   3 14.364 0.0506 470.0, 519.0 0.91
BXD44 m 600.0 0.0   9 0.0 0.0 600.0, 600.0 1.95
BXD45 m 288.5 28.641   4 14.321 0.0993 253.0, 318.0 -1.03
BXD48 m 473.2 71.73   4 35.864 0.1516 389.0, 562.0 0.73
BXD48a m 454.7 178.8   3 103.2 0.3932 249.0, 573.0 0.56
BXD49 m 236.5 18.376   4 9.1879 0.0777 214.0, 257.0 -1.53
BXD50 m 294.4 34.275   5 15.328 0.1164 247.0, 330.0 -0.97
BXD51 m 382.2 62.52   4 31.258 0.1635 305.0, 458.0 -0.13
BXD53 m 458.8 94.92   5 42.449 0.2069 340.0, 600.0 0.6
BXD55 m 251.5 26.901   4 13.451 0.107 214.0, 278.0 -1.38
BXD56 m 425.2 53.92   4 26.958 0.1268 374.0, 495.0 0.28
BXD6 m 357.2 42.151   5 18.85 0.118 319.0, 404.0 -0.37
BXD60 m 330.2 12.988   5 5.8086 0.0393 313.0, 348.0 -0.63
BXD61 m 321.0 95.39   5 42.661 0.2972 235.0, 479.0 -0.72
BXD62 m 370.8 137.5   4 68.77 0.371 265.0, 573.0 -0.24
BXD63 m 546.0 53.78   4 26.889 0.0985 473.0, 599.0 1.43
BXD64 m 511.0 111.8   4 55.92 0.2189 359.0, 600.0 1.1
BXD65 m 392.2 147.0   4 73.51 0.3748 255.0, 572.0 -0.04
BXD65a m 459.8 53.51   4 26.753 0.1164 420.0, 537.0 0.61
BXD66 m 257.8 13.326   4 6.663 0.0517 243.0, 274.0 -1.32
BXD67 m 412.8 51.22   5 22.905 0.1241 371.0, 501.0 0.16
BXD68 m 432.0 74.93   4 37.466 0.1735 357.0, 521.0 0.34
BXD69 m 586.8 29.516   5 13.2 0.0503 534.0, 600.0 1.82
BXD70 m 328.0 108.4   4 54.2 0.3305 230.0, 478.0 -0.65
BXD71 m 547.0 91.8   3 53.0 0.1678 441.0, 600.0 1.44
BXD73 m 330.6 91.38   5 40.866 0.2764 205.0, 455.0 -0.63
BXD73a m 301.0 39.791   4 19.896 0.1322 273.0, 360.0 -0.91
BXD73b m 301.8 90.57   5 40.504 0.3001 209.0, 445.0 -0.9
BXD75 m 380.2 67.05   5 29.986 0.1764 307.0, 460.0 -0.15
BXD77 m 492.8 81.46   5 36.429 0.1653 351.0, 554.0 0.92
BXD79 m 370.8 84.78   5 37.914 0.2286 263.0, 477.0 -0.24
BXD8 m 286.8 42.305   5 18.919 0.1475 242.0, 343.0 -1.05
BXD81 m 534.0 28.925   4 14.463 0.0542 508.0, 561.0 1.32
BXD83 m 342.8 121.7   4 60.87 0.3552 228.0, 461.0 -0.51
BXD84 m 500.0 83.05   3 47.948 0.1661 423.0, 588.0 0.99
BXD85 m 530.0 80.85   4 40.423 0.1525 458.0, 600.0 1.28
BXD87 m 325.8 56.27   5 25.166 0.1727 243.0, 393.0 -0.67
BXD89 m 285.2 90.16   4 45.082 0.3161 161.0, 372.0 -1.06
BXD90 m 291.2 34.625   4 17.313 0.1189 271.0, 343.0 -1.0
BXD95 m 425.4 41.052   5 18.359 0.0965 388.0, 470.0 0.28
BXD98 m 590.8 13.535   5 6.0531 0.0229 570.0, 600.0 1.86
BXD99 m 482.0 91.5   5 40.921 0.1898 335.0, 553.0 0.82
C57BL/6J m 302.5 70.53   4 35.267 0.2332 261.0, 408.0 -0.9
DBA/2J m 223.7 58.59   3 33.825 0.2619 167.0, 284.0 -1.65


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 398.2 32.1798308016 461.6713853641 334.7286146359
BXD100 m 381.4 32.1798308016 444.8713853641 317.9286146359
BXD101 m 300.0 35.9781445884 370.9631661501 229.0368338499
BXD11 m 329.4 32.1798308016 392.8713853641 265.9286146359
BXD12 m 271.6 32.1798308016 335.0713853641 208.1286146359
BXD16 m 544.4 32.1798308016 607.8713853641 480.9286146359
BXD2 m 240.8 32.1798308016 304.2713853641 177.3286146359
BXD27 m 553.25 35.9781445884 624.2131661501 482.2868338499
BXD32 m 368.3333333333 41.5439829261 450.274539492 286.3921271747
BXD34 m 338.6 32.1798308016 402.0713853641 275.1286146359
BXD39 m 540.2 32.1798308016 603.6713853641 476.7286146359
BXD40 m 418.0 35.9781445884 488.9631661501 347.0368338499
BXD43 m 492.0 41.5439829261 573.9412061586 410.0587938414
BXD44 m 600.0 23.9854297256 647.3087774334 552.6912225666
BXD45 m 288.5 35.9781445884 359.4631661501 217.5368338499
BXD48 m 473.25 35.9781445884 544.2131661501 402.2868338499
BXD48a m 454.6666666667 41.5439829261 536.6078728253 372.725460508
BXD49 m 236.5 35.9781445884 307.4631661501 165.5368338499
BXD50 m 294.4 32.1798308016 357.8713853641 230.9286146359
BXD51 m 382.25 35.9781445884 453.2131661501 311.2868338499
BXD53 m 458.8 32.1798308016 522.2713853641 395.3286146359
BXD55 m 251.5 35.9781445884 322.4631661501 180.5368338499
BXD56 m 425.25 35.9781445884 496.2131661501 354.2868338499
BXD6 m 357.2 32.1798308016 420.6713853641 293.7286146359
BXD60 m 330.2 32.1798308016 393.6713853641 266.7286146359
BXD61 m 321.0 32.1798308016 384.4713853641 257.5286146359
BXD62 m 370.75 35.9781445884 441.7131661501 299.7868338499
BXD63 m 546.0 35.9781445884 616.9631661501 475.0368338499
BXD64 m 511.0 35.9781445884 581.9631661501 440.0368338499
BXD65 m 392.25 35.9781445884 463.2131661501 321.2868338499
BXD65a m 459.75 35.9781445884 530.7131661501 388.7868338499
BXD66 m 257.75 35.9781445884 328.7131661501 186.7868338499
BXD67 m 412.8 32.1798308016 476.2713853641 349.3286146359
BXD68 m 432.0 35.9781445884 502.9631661501 361.0368338499
BXD69 m 586.8 32.1798308016 650.2713853641 523.3286146359
BXD70 m 328.0 35.9781445884 398.9631661501 257.0368338499
BXD71 m 547.0 41.5439829261 628.9412061586 465.0587938414
BXD73 m 330.6 32.1798308016 394.0713853641 267.1286146359
BXD73a m 301.0 35.9781445884 371.9631661501 230.0368338499
BXD73b m 301.8 32.1798308016 365.2713853641 238.3286146359
BXD75 m 380.2 32.1798308016 443.6713853641 316.7286146359
BXD77 m 492.8 32.1798308016 556.2713853641 429.3286146359
BXD79 m 370.8 32.1798308016 434.2713853641 307.3286146359
BXD8 m 286.8 32.1798308016 350.2713853641 223.3286146359
BXD81 m 534.0 35.9781445884 604.9631661501 463.0368338499
BXD83 m 342.75 35.9781445884 413.7131661501 271.7868338499
BXD84 m 500.0 41.5439829261 581.9412061586 418.0587938414
BXD85 m 530.0 35.9781445884 600.9631661501 459.0368338499
BXD87 m 325.8 32.1798308016 389.2713853641 262.3286146359
BXD89 m 285.25 35.9781445884 356.2131661501 214.2868338499
BXD90 m 291.25 35.9781445884 362.2131661501 220.2868338499
BXD95 m 425.4 32.1798308016 488.8713853641 361.9286146359
BXD98 m 590.8 32.1798308016 654.2713853641 527.3286146359
BXD99 m 482.0 32.1798308016 545.4713853641 418.5286146359
C57BL/6J m 302.5 35.9781445884 373.4631661501 231.5368338499
DBA/2J m 223.6666666667 41.5439829261 305.6078728253 141.725460508




  GWAS USING LINEAR MIXED MODELS