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Project measure / variable:   CSNA03   reinstatement_active_cc_s2

ID, description, units MPD:110419   reinstatement_active_cc_s2   reinstatement, active lever presses (intravenous self administration), CC   [n]  session 2  
cocaine study
Data set, strains CSNA03   CC w/par   54 strains     sex: both     age:
Procedure operant conditioning chamber
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  STRAIN COMPARISON PLOT
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CSNA03 - reinstatement, active lever presses (intravenous self administration), CC session 2



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested52 strains51 strains
Mean of the strain means338.3   n 98.83   n
Median of the strain means103.1   n 70.0   n
SD of the strain means± 898.2 ± 112.5
Coefficient of variation (CV)2.6553 1.138
Min–max range of strain means0.0   –   5754.0   n 0.0   –   711.5   n
Mean sample size per strain3.2   mice 3.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 4683843.2196 4683843.2196 10.4749 0.0014
strain 39 75490064.1859 1935642.6714 4.3289 < 0.0001
sex:strain 39 51142142.7354 1311336.9932 2.9327 < 0.0001
Residuals 240 107315381.7466 447147.4239


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
A/J f 64.44 65.34   9 21.781 1.0139 1.0, 210.0 -0.3
A/J m 61.43 51.61   7 19.506 0.8401 -0.33
C57BL/6J f 202.3 145.8   12 42.093 0.7207 19.0, 500.0 -0.15
C57BL/6J m 76.23 60.46   13 16.768 0.7931 5.0, 229.0 -0.2
CAST/EiJ f 160.0 0.0   1   0.0 0.0 160.0, 160.0 -0.2
CAST/EiJ m 66.5 72.83   2   51.5 1.0952 15.0, 118.0 -0.29
CC001/UncJ f 66.33 25.403   3 14.667 0.383 37.0, 81.0 -0.3
CC001/UncJ m 102.0 87.39   4 43.694 0.8567 28.0, 201.0 0.03
CC002/UncJ f 5754.0 6262.0   3 3615.0 1.0882 60.0, 12460.0 6.03
CC002/UncJ m 126.0 11.314   2   8.0 0.0898 118.0, 134.0 0.24
CC003/UncJ f 48.0 12.728   2   9.0 0.2652 39.0, 57.0 -0.32
CC003/UncJ m 17.25 20.71   4 10.355 1.2006 4.0, 48.0 -0.73
CC004/TauUncJ f 306.1 201.3   9 67.11 0.6577 31.0, 533.0 -0.04
CC004/TauUncJ m 342.2 256.0   19 58.72 0.7479 40.0, 880.0 2.16
CC005/TauUncJ f 32.75 5.8523   4 2.9262 0.1787 24.0, 36.0 -0.34
CC005/TauUncJ m 30.5 0.70711   2   0.5 0.0232 30.0, 31.0 -0.61
CC006/TauUncJ f 127.5 43.134   2   30.5 0.3383 97.0, 158.0 -0.23
CC006/TauUncJ m 711.5 1005.0   2   710.5 1.4122 1.0, 1422.0 5.45
CC007/UncJ f 150.5 210.0   2   148.5 1.3954 2.0, 299.0 -0.21
CC007/UncJ m 67.33 68.53   3 39.566 1.0178 -0.28
CC008/GeniUncJ f 7.0 2.8284   2   2.0 0.4041 5.0, 9.0 -0.37
CC008/GeniUncJ m 100.0 22.627   2   16.0 0.2263 84.0, 116.0 0.01
CC009/UncJ f 140.3 147.4   3 85.08 1.0501 3.0, 296.0 -0.22
CC009/UncJ m 24.0 39.85   3 23.007 1.6604 -0.67
CC011/UncJ f 199.3 145.9   3 84.23 0.7319 73.0, 359.0 -0.15
CC011/UncJ m 67.33 21.008   3 12.129 0.312 46.0, 88.0 -0.28
CC012/GeniUncJ f 263.0 0.0   1   0.0 0.0 263.0, 263.0 -0.08
CC012/GeniUncJ m 190.7 211.6   3 122.2 1.1099 16.0, 426.0 0.82
CC013/GeniUncJ f 398.0 328.5   3 189.7 0.8254 21.0, 623.0 0.07
CC013/GeniUncJ m 107.0 83.14   3 48.003 0.7771 35.0, 198.0 0.07
CC015/UncJ f 45.0 57.98   2   41.0 1.2885 4.0, 86.0 -0.33
CC015/UncJ m 70.0 0.0   1   0.0 0.0 70.0, 70.0 -0.26
CC016/GeniUncJ f 642.0 899.4   2   636.0 1.401 6.0, 1278.0 0.34
CC016/GeniUncJ m 12.0 7.0711   2   5.0 0.5893 7.0, 17.0 -0.77
CC017/UncJ f 19.333 10.693   3 6.1734 0.5531 10.0, 31.0 -0.36
CC017/UncJ m 5.0 2.0   4 1.0 0.4 4.0, 8.0 -0.83
CC018/UncJ f 329.0 272.0   3 157.0 0.8267 15.0, 491.0 -0.01
CC018/UncJ m 175.0 67.86   5 30.346 0.3878 109.0, 281.0 0.68
CC019/TauUncJ f 326.8 280.4   5 125.4 0.8581 44.0, 686.0 -0.01
CC019/TauUncJ m 69.0 59.81   3 34.53 0.8668 13.0, 132.0 -0.27
CC020/GeniUncJ f 125.0 0.0   1   0.0 0.0 125.0, 125.0 -0.24
CC023/GeniUncJ f 37.667 33.322   3 19.238 0.8846 2.0, 68.0 -0.33
CC023/GeniUncJ m 48.667 26.764   3 15.452 0.55 20.0, 73.0 -0.45
CC024/GeniUncJ f 52.5 74.25   2   52.5 1.4142 -0.32
CC024/GeniUncJ m 28.5 40.305   2   28.5 1.4142 -0.63
CC025/GeniUncJ f 129.5 152.0   2   107.5 1.174 22.0, 237.0 -0.23
CC025/GeniUncJ m 54.0 0.0   1   0.0 0.0 54.0, 54.0 -0.4
CC026/GeniUncJ f 33.8 21.959   5 9.8204 0.6497 6.0, 62.0 -0.34
CC026/GeniUncJ m 29.667 15.503   3 8.9505 0.5226 14.0, 45.0 -0.61
CC027/GeniUncJ f 303.0 421.8   4 210.9 1.3919 4.0, 903.0 -0.04
CC027/GeniUncJ m 74.25 61.48   4 30.742 0.8281 13.0, 154.0 -0.22
CC028/GeniUncJ f 178.5 151.3   4 75.67 0.8478 84.0, 403.0 -0.18
CC028/GeniUncJ m 95.2 48.628   5 21.747 0.5108 48.0, 151.0 -0.03
CC029/UncJ f 1.0 0.0   1   0.0 0.0 1.0, 1.0 -0.38
CC029/UncJ m 32.0 0.0   1   0.0 0.0 32.0, 32.0 -0.59
CC030/GeniUncJ f 102.5 145.0   2   102.5 1.4142 -0.26
CC030/GeniUncJ m 126.0 103.2   2   73.0 0.8193 53.0, 199.0 0.24
CC032/GeniUncJ f 52.67 2.0817   3 1.2019 0.0395 51.0, 55.0 -0.32
CC032/GeniUncJ m 143.0 234.5   4 117.3 1.6399 5.0, 493.0 0.39
CC033/GeniUncJ f 46.0 0.0   1   0.0 0.0 46.0, 46.0 -0.33
CC033/GeniUncJ m 68.0 60.81   2   43.0 0.8943 25.0, 111.0 -0.27
CC035/UncJ f 53.33 6.1101   3 3.5277 0.1146 48.0, 60.0 -0.32
CC035/UncJ m 153.5 132.2   2   93.5 0.8614 60.0, 247.0 0.49
CC036/UncJ f 238.3 143.5   3 82.86 0.6022 134.0, 402.0 -0.11
CC036/UncJ m 115.5 102.5   2   72.5 0.8877 43.0, 188.0 0.15
CC037/TauUncJ f 24.0 0.0   1   0.0 0.0 24.0, 24.0 -0.35
CC037/TauUncJ m 0.0 0.0   1   0.0 None -0.88
CC040/TauUncJ f 65.5 88.39   2   62.5 1.3494 3.0, 128.0 -0.3
CC040/TauUncJ m 126.5 20.506   2   14.5 0.1621 112.0, 141.0 0.25
CC041/TauUncJ f 54.0 76.37   2   54.0 1.4142 -0.32
CC041/TauUncJ m 6.4167 11.72   12 3.3832 1.8265 -0.82
CC043/GeniUncJ m 13.0 0.0   1   0.0 0.0 13.0, 13.0 -0.76
CC044/UncJ f 3.0 4.2426   2   3.0 1.4142 -0.37
CC044/UncJ m 75.5 89.8   2   63.5 1.1894 12.0, 139.0 -0.21
CC051/TauUncJ f 91.5 33.234   2   23.5 0.3632 68.0, 115.0 -0.27
CC051/TauUncJ m 95.33 57.55   3 33.228 0.6037 47.0, 159.0 -0.03
CC057/UncJ f 2098.0 2941.0   2   2080.0 1.4014 19.0, 4178.0 1.96
CC057/UncJ m 40.5 7.7782   2   5.5 0.1921 35.0, 46.0 -0.52
CC059/TauUncJ f 2705.0 2113.0   4 1057.0 0.7813 33.0, 4898.0 2.64
CC059/TauUncJ m 179.7 108.2   3 62.44 0.602 101.0, 303.0 0.72
CC060/UncJ m 72.0 0.0   1   0.0 0.0 72.0, 72.0 -0.24
CC061/GeniUncJ f 358.5 409.4   2   289.5 1.142 69.0, 648.0 0.02
CC061/GeniUncJ m 192.0 138.6   2   98.0 0.7218 94.0, 290.0 0.83
CC068/TauUncJ f 0.0 0.0   2   0.0 None -0.38
CC068/TauUncJ m 1.5 2.1213   2   1.5 1.4142 -0.87
CC074/UncJ f 12.0 0.0   1   0.0 0.0 12.0, 12.0 -0.36
CC074/UncJ m 58.0 0.0   1   0.0 0.0 58.0, 58.0 -0.36
CC075/UncJ f 5.0 0.0   1   0.0 0.0 5.0, 5.0 -0.37
CC078/TauUncJ f 811.0 868.3   2   614.0 1.0707 197.0, 1425.0 0.53
CC078/TauUncJ m 328.7 210.0   3 121.2 0.639 93.0, 496.0 2.04
CC079/TauUncJ f 181.5 26.163   2   18.5 0.1441 163.0, 200.0 -0.17
CC079/TauUncJ m 99.5 116.7   2   82.5 1.1726 17.0, 182.0 0.01
CC080/TauUncJ f 4.5 6.364   2   4.5 1.4142 -0.37
CC084/TauJ f 166.5 129.4   2   91.5 0.7772 75.0, 258.0 -0.19
CC084/TauJ m 53.0 0.0   1   0.0 0.0 53.0, 53.0 -0.41
NOD/ShiLtJ f 87.27 141.3   11 42.595 1.6187 2.0, 482.0 -0.28
NOD/ShiLtJ m 70.33 50.31   6 20.537 0.7152 12.0, 136.0 -0.25
NZO/HlLtJ f 51.9 39.267   10 12.417 0.7566 -0.32
NZO/HlLtJ m 53.0 29.518   10 9.3345 0.557 9.0, 118.0 -0.41
PWK/PhJ f 130.9 77.99   7 29.479 0.596 60.0, 261.0 -0.23
PWK/PhJ m 117.8 65.55   6 26.761 0.5563 32.0, 230.0 0.17
WSB/EiJ f 103.7 83.77   3 48.364 0.8081 7.0, 155.0 -0.26
WSB/EiJ m 68.4 39.488   5 17.66 0.5773 16.0, 113.0 -0.27


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J f 64.4444444444 222.8969427895 503.5286049113 -374.6397160225
A/J m 61.4285714286 252.7413765504 559.3032113813 -436.4460685241
C57BL/6J f 202.3333333333 193.0344148816 582.591370697 -177.9247040304
C57BL/6J m 76.2307692308 185.461466855 441.5708741863 -289.1093357248
CC001/UncJ f 66.3333333333 386.0688297632 826.8494080607 -694.182741394
CC001/UncJ m 102.0 334.3454141843 760.6262407003 -556.6262407003
CC002/UncJ f 5754.0 386.0688297632 6514.5160747274 4993.4839252727
CC002/UncJ m 126.0 472.8358192566 1057.4381621333 -805.4381621332
CC003/UncJ f 48.0 472.8358192567 979.4381621332 -883.4381621332
CC003/UncJ m 17.25 334.3454141843 675.8762407003 -641.3762407003
CC004/TauUncJ f 306.1111111111 222.8969427895 745.195271578 -132.9730493558
CC004/TauUncJ m 342.2105263158 153.4081971227 644.4089710291 40.0120816024
CC005/TauUncJ f 32.75 334.3454141843 691.3762407003 -625.8762407003
CC005/TauUncJ m 30.5 472.8358192567 961.9381621332 -900.9381621332
CC006/TauUncJ f 127.5 472.8358192567 1058.9381621332 -803.9381621332
CC006/TauUncJ m 711.5 472.8358192567 1642.9381621332 -219.9381621332
CC007/UncJ f 150.5 472.8358192566 1081.9381621332 -780.9381621332
CC007/UncJ m 67.3333333333 386.0688297632 827.8494080607 -693.1827413941
CC008/GeniUncJ f 7.0 472.8358192567 938.4381621332 -924.4381621332
CC008/GeniUncJ m 100.0 472.8358192566 1031.4381621332 -831.4381621332
CC009/UncJ f 140.3333333333 386.0688297632 900.8494080607 -620.1827413941
CC009/UncJ m 24.0 386.0688297632 784.5160747274 -736.5160747274
CC011/UncJ f 199.3333333333 386.0688297632 959.8494080607 -561.1827413941
CC011/UncJ m 67.3333333333 386.0688297632 827.8494080607 -693.1827413941
CC013/GeniUncJ f 398.0 386.0688297632 1158.5160747274 -362.5160747274
CC013/GeniUncJ m 107.0 386.0688297632 867.5160747274 -653.5160747274
CC016/GeniUncJ f 642.0 472.8358192567 1573.4381621332 -289.4381621332
CC016/GeniUncJ m 12.0 472.8358192567 943.4381621332 -919.4381621332
CC017/UncJ f 19.3333333333 386.0688297632 779.8494080607 -741.1827413941
CC017/UncJ m 5.0 334.3454141843 663.6262407003 -653.6262407003
CC018/UncJ f 329.0 386.0688297632 1089.5160747274 -431.5160747274
CC018/UncJ m 175.0 299.0476296325 764.0932183884 -414.0932183884
CC019/TauUncJ f 326.8 299.0476296325 915.8932183884 -262.2932183884
CC019/TauUncJ m 69.0 386.0688297632 829.5160747274 -691.5160747274
CC023/GeniUncJ f 37.6666666667 386.0688297632 798.182741394 -722.8494080607
CC023/GeniUncJ m 48.6666666667 386.0688297632 809.1827413941 -711.8494080607
CC024/GeniUncJ f 52.5 472.8358192567 983.9381621332 -878.9381621332
CC024/GeniUncJ m 28.5 472.8358192567 959.9381621332 -902.9381621332
CC026/GeniUncJ f 33.8 299.0476296325 622.8932183884 -555.2932183884
CC026/GeniUncJ m 29.6666666667 386.0688297632 790.182741394 -730.8494080607
CC027/GeniUncJ f 303.0 334.3454141843 961.6262407003 -355.6262407003
CC027/GeniUncJ m 74.25 334.3454141843 732.8762407003 -584.3762407003
CC028/GeniUncJ f 178.5 334.3454141843 837.1262407003 -480.1262407003
CC028/GeniUncJ m 95.2 299.0476296325 684.2932183884 -493.8932183884
CC030/GeniUncJ f 102.5 472.8358192566 1033.9381621332 -828.9381621332
CC030/GeniUncJ m 126.0 472.8358192567 1057.4381621332 -805.4381621332
CC032/GeniUncJ f 52.6666666667 386.0688297632 813.182741394 -707.8494080607
CC032/GeniUncJ m 143.0 334.3454141843 801.6262407003 -515.6262407003
CC035/UncJ f 53.3333333333 386.0688297632 813.8494080607 -707.1827413941
CC035/UncJ m 153.5 472.8358192566 1084.9381621332 -777.9381621332
CC036/UncJ f 238.3333333333 386.0688297632 998.8494080607 -522.1827413941
CC036/UncJ m 115.5 472.8358192566 1046.9381621332 -815.9381621332
CC040/TauUncJ f 65.5 472.8358192567 996.9381621332 -865.9381621332
CC040/TauUncJ m 126.5 472.8358192567 1057.9381621332 -804.9381621332
CC041/TauUncJ f 54.0 472.8358192567 985.4381621332 -877.4381621332
CC041/TauUncJ m 6.4166666667 193.0344148816 386.6747040304 -373.841370697
CC044/UncJ f 3.0 472.8358192567 934.4381621332 -928.4381621332
CC044/UncJ m 75.5 472.8358192567 1006.9381621332 -855.9381621332
CC051/TauUncJ f 91.5 472.8358192566 1022.9381621332 -839.9381621332
CC051/TauUncJ m 95.3333333333 386.0688297632 855.8494080607 -665.1827413941
CC057/UncJ f 2098.5 472.8358192567 3029.9381621332 1167.0618378668
CC057/UncJ m 40.5 472.8358192566 971.9381621332 -890.9381621332
CC059/TauUncJ f 2704.75 334.3454141843 3363.3762407003 2046.1237592997
CC059/TauUncJ m 179.6666666667 386.0688297632 940.182741394 -580.8494080607
CC061/GeniUncJ f 358.5 472.8358192566 1289.9381621332 -572.9381621332
CC061/GeniUncJ m 192.0 472.8358192567 1123.4381621332 -739.4381621332
CC068/TauUncJ f 0.0 472.8358192567 931.4381621332 -931.4381621332
CC068/TauUncJ m 1.5 472.8358192567 932.9381621332 -929.9381621332
CC078/TauUncJ f 811.0 472.8358192567 1742.4381621332 -120.4381621332
CC078/TauUncJ m 328.6666666667 386.0688297632 1089.182741394 -431.8494080607
CC079/TauUncJ f 181.5 472.8358192567 1112.9381621332 -749.9381621332
CC079/TauUncJ m 99.5 472.8358192567 1030.9381621332 -831.9381621332
NOD/ShiLtJ f 87.2727272727 201.6178707682 484.4392940882 -309.8938395428
NOD/ShiLtJ m 70.3333333333 272.9918875303 608.0994069744 -467.4327403078
NZO/HlLtJ f 51.9 211.4586068109 468.4518094735 -364.6518094735
NZO/HlLtJ m 53.0 211.4586068109 469.5518094735 -363.5518094735
PWK/PhJ f 130.8571428571 252.7413765504 628.7317828098 -367.0174970956
PWK/PhJ m 117.8333333333 272.9918875303 655.5994069744 -419.9327403078
WSB/EiJ f 103.6666666667 386.0688297632 864.1827413941 -656.8494080607
WSB/EiJ m 68.4 299.0476296325 657.4932183884 -520.6932183884


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
A/J both 62.9365079365 168.4942510336 394.8529345716 -268.9799186986
C57BL/6J both 139.2820512821 133.8452847663 402.9435612094 -124.3794586453
CC001/UncJ both 84.1666666667 255.3605281268 587.2007671156 -418.8674337822
CC002/UncJ both 2940.0 305.2142089119 3541.2407483274 2338.7592516727
CC003/UncJ both 32.625 289.5516223224 603.0120560455 -537.7620560455
CC004/TauUncJ both 324.1608187134 135.2933128885 590.6747958141 57.6468416128
CC005/TauUncJ both 31.625 289.5516223224 602.0120560455 -538.7620560455
CC006/TauUncJ both 419.5 334.3454141843 1078.1262407003 -239.1262407003
CC007/UncJ both 108.9166666667 305.2142089119 710.157414994 -492.3240816607
CC008/GeniUncJ both 53.5 334.3454141843 712.1262407003 -605.1262407003
CC009/UncJ both 82.1666666667 272.9918875303 619.9327403078 -455.5994069744
CC011/UncJ both 133.3333333333 272.9918875303 671.0994069744 -404.4327403078
CC013/GeniUncJ both 252.5 272.9918875303 790.2660736411 -285.2660736411
CC016/GeniUncJ both 327.0 334.3454141843 985.6262407003 -331.6262407003
CC017/UncJ both 12.1666666667 255.3605281268 515.2007671156 -490.8674337823
CC018/UncJ both 252.0 244.1713671295 732.9925986619 -228.9925986619
CC019/TauUncJ both 197.9 244.1713671295 678.8925986619 -283.0925986619
CC023/GeniUncJ both 43.1666666667 272.9918875303 580.9327403078 -494.5994069744
CC024/GeniUncJ both 40.5 334.3454141843 699.1262407003 -618.1262407003
CC026/GeniUncJ both 31.7333333333 244.1713671295 512.7259319952 -449.2592653285
CC027/GeniUncJ both 188.625 236.4179096283 654.3440810666 -277.0940810666
CC028/GeniUncJ both 136.85 224.2857222244 578.6699137913 -304.9699137913
CC030/GeniUncJ both 114.25 334.3454141843 772.8762407003 -544.3762407003
CC032/GeniUncJ both 97.8333333333 255.3605281268 600.8674337823 -405.2007671156
CC035/UncJ both 103.4166666667 305.2142089119 704.657414994 -497.8240816607
CC036/UncJ both 176.9166666667 305.2142089119 778.157414994 -424.3240816607
CC040/TauUncJ both 96.0 334.3454141843 754.6262407003 -562.6262407003
CC041/TauUncJ both 30.2083333333 255.3605281268 533.2424337823 -472.8257671156
CC044/UncJ both 39.25 334.3454141843 697.8762407003 -619.3762407003
CC051/TauUncJ both 93.4166666667 305.2142089119 694.657414994 -507.8240816607
CC057/UncJ both 1069.5 334.3454141843 1728.1262407003 410.8737592997
CC059/TauUncJ both 1442.2083333333 255.3605281268 1945.2424337823 939.1742328844
CC061/GeniUncJ both 275.25 334.3454141843 933.8762407003 -383.3762407003
CC068/TauUncJ both 0.75 334.3454141843 659.3762407003 -657.8762407003
CC078/TauUncJ both 569.8333333333 305.2142089119 1171.0740816607 -31.407414994
CC079/TauUncJ both 140.5 334.3454141843 799.1262407003 -518.1262407003
NOD/ShiLtJ both 78.803030303 169.6867234571 413.0685055452 -255.4624449391
NZO/HlLtJ both 52.45 149.5238148163 346.9966091942 -242.0966091942
PWK/PhJ both 124.3452380952 186.01261656 490.7710515512 -242.0805753607
WSB/EiJ both 86.0333333333 244.1713671295 567.0259319952 -394.9592653285




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA