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Project measure / variable:   CSNA03   extinction_inactive_cc_s8

ID, description, units MPD:110416   extinction_inactive_cc_s8   extinction, inactive lever presses (intravenous self administration), CC   [n]  session 8  
cocaine study
Data set, strains CSNA03   CC w/par   37 strains     sex: both     age:
Procedure operant conditioning chamber
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  STRAIN COMPARISON PLOT
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CSNA03 - extinction, inactive lever presses (intravenous self administration), CC session 8



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested27 strains25 strains
Mean of the strain means96.91   n 197.2   n
Median of the strain means66.0   n 45.0   n
SD of the strain means± 96.95 ± 383.7
Coefficient of variation (CV)1.0004 1.9461
Min–max range of strain means4.0   –   384.3   n 0.0   –   1862.0   n
Mean sample size per strain1.6   mice 1.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 407287.4423 407287.4423 3.3671 0.0864
strain 4 2084179.5514 521044.8878 4.3075 0.0162
sex:strain 4 2927400.173 731850.0432 6.0503 0.0042
Residuals 15 1814416.8333 120961.1222


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
C57BL/6J f 9.0 0.0   1   0.0 0.0 9.0, 9.0 -0.91
CC001/UncJ f 6.0 0.0   1   0.0 0.0 6.0, 6.0 -0.94
CC001/UncJ m 211.0 107.5   2   76.0 0.5094 135.0, 287.0 0.04
CC002/UncJ f 384.3 334.2   3 192.9 0.8694 157.0, 768.0 2.96
CC003/UncJ f 169.0 0.0   1   0.0 0.0 169.0, 169.0 0.74
CC003/UncJ m 4.0 0.0   1   0.0 0.0 4.0, 4.0 -0.5
CC004/TauUncJ f 81.0 0.0   1   0.0 0.0 81.0, 81.0 -0.16
CC004/TauUncJ m 153.3 164.6   7 62.22 1.074 -0.11
CC005/TauUncJ f 4.0 0.0   1   0.0 0.0 4.0, 4.0 -0.96
CC006/TauUncJ m 46.0 0.0   1   0.0 0.0 46.0, 46.0 -0.39
CC007/UncJ f 106.0 0.0   1   0.0 0.0 106.0, 106.0 0.09
CC007/UncJ m 22.0 4.2426   2   3.0 0.1928 19.0, 25.0 -0.46
CC008/GeniUncJ m 11.0 15.556   2   11.0 1.4142 -0.49
CC009/UncJ f 19.0 0.0   1   0.0 0.0 19.0, 19.0 -0.8
CC011/UncJ f 109.0 60.81   2   43.0 0.5579 66.0, 152.0 0.12
CC011/UncJ m 320.5 16.263   2   11.5 0.0507 309.0, 332.0 0.32
CC012/GeniUncJ m 45.0 0.0   1   0.0 0.0 45.0, 45.0 -0.4
CC013/GeniUncJ f 305.0 42.426   2   30.0 0.1391 275.0, 335.0 2.15
CC013/GeniUncJ m 224.0 210.7   2   149.0 0.9407 75.0, 373.0 0.07
CC018/UncJ f 137.3 118.4   3 68.37 0.8623 6.0, 236.0 0.42
CC018/UncJ m 57.0 26.796   4 13.398 0.4701 28.0, 91.0 -0.37
CC019/TauUncJ f 220.0 305.7   3 176.5 1.3896 43.0, 573.0 1.27
CC019/TauUncJ m 120.5 152.0   2   107.5 1.2616 13.0, 228.0 -0.2
CC023/GeniUncJ f 6.0 0.0   1   0.0 0.0 6.0, 6.0 -0.94
CC023/GeniUncJ m 247.0 0.0   1   0.0 0.0 247.0, 247.0 0.13
CC024/GeniUncJ f 23.0 0.0   1   0.0 0.0 23.0, 23.0 -0.76
CC025/GeniUncJ f 191.0 0.0   1   0.0 0.0 191.0, 191.0 0.97
CC025/GeniUncJ m 405.0 0.0   1   0.0 0.0 405.0, 405.0 0.54
CC027/GeniUncJ f 27.0 0.0   1   0.0 0.0 27.0, 27.0 -0.72
CC028/GeniUncJ f 124.0 111.0   3 64.08 0.8951 29.0, 246.0 0.28
CC028/GeniUncJ m 29.0 0.0   1   0.0 0.0 29.0, 29.0 -0.44
CC030/GeniUncJ m 335.0 0.0   1   0.0 0.0 335.0, 335.0 0.36
CC032/GeniUncJ f 66.0 0.0   1   0.0 0.0 66.0, 66.0 -0.32
CC033/GeniUncJ m 12.0 0.0   1   0.0 0.0 12.0, 12.0 -0.48
CC036/UncJ f 126.7 134.0   3 77.36 1.0578 40.0, 281.0 0.31
CC036/UncJ m 672.0 0.0   1   0.0 0.0 672.0, 672.0 1.24
CC040/TauUncJ m 5.0 0.0   1   0.0 0.0 5.0, 5.0 -0.5
CC041/TauUncJ m 0.0 0.0   1   0.0 None -0.51
CC044/UncJ f 8.0 0.0   1   0.0 0.0 8.0, 8.0 -0.92
CC044/UncJ m 34.0 0.0   1   0.0 0.0 34.0, 34.0 -0.43
CC051/TauUncJ m 1.0 0.0   1   0.0 0.0 1.0, 1.0 -0.51
CC057/UncJ f 18.0 0.0   1   0.0 0.0 18.0, 18.0 -0.81
CC059/TauUncJ f 167.3 121.0   3 69.88 0.7233 93.0, 307.0 0.73
CC059/TauUncJ m 1862.0 1223.0   2   864.5 0.6564 998.0, 2727.0 4.34
CC060/UncJ m 42.0 0.0   1   0.0 0.0 42.0, 42.0 -0.4
CC061/GeniUncJ m 35.0 0.0   1   0.0 0.0 35.0, 35.0 -0.42
CC078/TauUncJ f 141.0 0.0   1   0.0 0.0 141.0, 141.0 0.45
CC078/TauUncJ m 36.0 0.0   1   0.0 0.0 36.0, 36.0 -0.42
CC079/TauUncJ f 35.5 3.5355   2   2.5 0.0996 33.0, 38.0 -0.63
CC084/TauJ f 62.0 0.0   1   0.0 0.0 62.0, 62.0 -0.36
NOD/ShiLtJ f 6.0 0.0   1   0.0 0.0 6.0, 6.0 -0.94
WSB/EiJ f 65.5 77.07   2   54.5 1.1767 11.0, 120.0 -0.32


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
CC011/UncJ f 109.0 245.9279591895 633.1830368549 -415.1830368549
CC011/UncJ m 320.5 245.9279591895 844.6830368549 -203.6830368549
CC013/GeniUncJ f 305.0 245.9279591895 829.1830368549 -219.1830368549
CC013/GeniUncJ m 224.0 245.9279591895 748.1830368549 -300.1830368549
CC018/UncJ f 137.3333333333 200.7993378328 565.3269907057 -290.660324039
CC018/UncJ m 57.0 173.8973276263 427.6533799431 -313.6533799431
CC019/TauUncJ f 220.0 200.7993378328 647.9936573723 -207.9936573723
CC019/TauUncJ m 120.5 245.9279591895 644.6830368549 -403.6830368549
CC059/TauUncJ f 167.3333333333 200.7993378328 595.3269907057 -260.660324039
CC059/TauUncJ m 1862.5 245.9279591895 2386.6830368549 1338.3169631451


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
CC011/UncJ both 214.75 173.8973276263 585.4033799431 -155.9033799431
CC013/GeniUncJ both 264.5 173.8973276263 635.1533799431 -106.1533799431
CC018/UncJ both 97.1666666667 132.816277833 380.2578616967 -185.9245283634
CC019/TauUncJ both 170.25 158.7458150513 508.6086953506 -168.1086953506
CC059/TauUncJ both 1014.9166666667 158.7458150513 1353.2753620172 676.5579713161




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA