Project measure / variable:   CSNA03   extinction_inactive_cc_s5

ID, description, units MPD:110413   extinction_inactive_cc_s5   extinction, inactive lever presses (intravenous self administration), CC   [n]  session 5  
cocaine study
Data set, strains CSNA03   CC w/par   46 strains     sex: both     age:
Procedure operant conditioning chamber
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  STRAIN COMPARISON PLOT
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CSNA03 - extinction, inactive lever presses (intravenous self administration), CC session 5



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested39 strains40 strains
Mean of the strain means99.82   n 100.1   n
Median of the strain means56.0   n 33.0   n
SD of the strain means± 136.0 ± 179.4
Coefficient of variation (CV)1.3628 1.7923
Min–max range of strain means0.0   –   735.7   n 0.0   –   759.5   n
Mean sample size per strain2.9   mice 3.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 16689.5422 16689.5422 1.6279 0.2042
strain 14 1367449.6242 97674.9732 9.5272 < 0.0001
sex:strain 14 185922.0953 13280.1497 1.2953 0.2183
Residuals 133 1363547.2658 10252.2351


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
A/J f 20.286 28.182   7 10.652 1.3893 2.0, 76.0 -0.58
A/J m 85.43 190.9   7 72.15 2.2344 -0.08
C57BL/6J f 40.727 77.16   11 23.265 1.8946 -0.43
C57BL/6J m 9.4545 10.367   11 3.1257 1.0965 2.0, 37.0 -0.51
CAST/EiJ f 41.0 0.0   1   0.0 0.0 41.0, 41.0 -0.43
CAST/EiJ m 21.5 30.406   2   21.5 1.4142 -0.44
CC001/UncJ f 56.0 35.763   3 20.648 0.6386 18.0, 89.0 -0.32
CC001/UncJ m 94.25 110.4   4 55.22 1.1718 6.0, 255.0 -0.03
CC002/UncJ f 735.7 1114.0   3 643.1 1.5142 32.0, 2020.0 4.67
CC003/UncJ f 67.0 0.0   1   0.0 0.0 67.0, 67.0 -0.24
CC003/UncJ m 6.3333 5.0332   3 2.9059 0.7947 1.0, 11.0 -0.52
CC004/TauUncJ f 95.75 95.6   8 33.8 0.9984 24.0, 298.0 -0.03
CC004/TauUncJ m 139.5 207.6   17 50.34 1.4882 1.0, 884.0 0.22
CC005/TauUncJ f 16.0 0.0   1   0.0 0.0 16.0, 16.0 -0.62
CC005/TauUncJ m 0.0 0.0   1   0.0 None -0.56
CC006/TauUncJ f 92.0 0.0   1   0.0 0.0 92.0, 92.0 -0.06
CC006/TauUncJ m 59.0 0.0   1   0.0 0.0 59.0, 59.0 -0.23
CC007/UncJ m 20.5 10.607   2   7.5 0.5174 13.0, 28.0 -0.44
CC008/GeniUncJ m 31.5 27.577   2   19.5 0.8755 12.0, 51.0 -0.38
CC009/UncJ f 107.0 0.0   1   0.0 0.0 107.0, 107.0 0.05
CC009/UncJ m 8.0 0.0   1   0.0 0.0 8.0, 8.0 -0.51
CC011/UncJ f 77.67 68.53   3 39.566 0.8824 8.0, 145.0 -0.16
CC011/UncJ m 159.3 102.0   3 58.89 0.6402 58.0, 262.0 0.33
CC012/GeniUncJ f 110.0 0.0   1   0.0 0.0 110.0, 110.0 0.07
CC012/GeniUncJ m 91.0 0.0   1   0.0 0.0 91.0, 91.0 -0.05
CC013/GeniUncJ f 345.0 0.0   1   0.0 0.0 345.0, 345.0 1.8
CC013/GeniUncJ m 92.0 83.37   3 48.135 0.9062 27.0, 186.0 -0.05
CC016/GeniUncJ f 55.0 0.0   1   0.0 0.0 55.0, 55.0 -0.33
CC017/UncJ m 1.0 0.0   1   0.0 0.0 1.0, 1.0 -0.55
CC018/UncJ f 111.7 68.07   3 39.299 0.6096 35.0, 165.0 0.09
CC018/UncJ m 63.75 25.76   4 12.88 0.4041 46.0, 101.0 -0.2
CC019/TauUncJ f 108.8 110.5   4 55.24 1.016 26.0, 271.0 0.07
CC019/TauUncJ m 87.5 101.1   2   71.5 1.1556 16.0, 159.0 -0.07
CC023/GeniUncJ f 31.5 6.364   2   4.5 0.202 27.0, 36.0 -0.5
CC023/GeniUncJ m 41.333 64.73   3 37.373 1.5661 1.0, 116.0 -0.33
CC024/GeniUncJ f 80.0 0.0   1   0.0 0.0 80.0, 80.0 -0.15
CC025/GeniUncJ m 374.0 0.0   1   0.0 0.0 374.0, 374.0 1.53
CC026/GeniUncJ f 9.4 8.1731   5 3.6551 0.8695 1.0, 23.0 -0.66
CC026/GeniUncJ m 4.3333 0.57735   3 0.33333 0.1332 4.0, 5.0 -0.53
CC027/GeniUncJ f 32.0 0.0   1   0.0 0.0 32.0, 32.0 -0.5
CC027/GeniUncJ m 19.0 0.0   1   0.0 0.0 19.0, 19.0 -0.45
CC028/GeniUncJ f 169.0 22.627   2   16.0 0.1339 153.0, 185.0 0.51
CC028/GeniUncJ m 47.0 21.213   2   15.0 0.4513 32.0, 62.0 -0.3
CC030/GeniUncJ f 175.5 67.18   2   47.5 0.3828 128.0, 223.0 0.56
CC030/GeniUncJ m 333.0 0.0   1   0.0 0.0 333.0, 333.0 1.3
CC032/GeniUncJ f 50.0 0.0   1   0.0 0.0 50.0, 50.0 -0.37
CC032/GeniUncJ m 20.667 6.8069   3 3.9299 0.3294 13.0, 26.0 -0.44
CC033/GeniUncJ m 12.0 0.0   1   0.0 0.0 12.0, 12.0 -0.49
CC035/UncJ f 0.0 0.0   1   0.0 None -0.73
CC035/UncJ m 34.5 20.506   2   14.5 0.5944 20.0, 49.0 -0.37
CC036/UncJ f 201.5 170.4   2   120.5 0.8457 81.0, 322.0 0.75
CC036/UncJ m 414.0 0.0   1   0.0 0.0 414.0, 414.0 1.75
CC037/TauUncJ f 11.0 0.0   1   0.0 0.0 11.0, 11.0 -0.65
CC040/TauUncJ m 5.0 0.0   1   0.0 0.0 5.0, 5.0 -0.53
CC041/TauUncJ f 111.5 157.7   2   111.5 1.4142 0.09
CC041/TauUncJ m 0.0 0.0   1   0.0 None -0.56
CC043/GeniUncJ m 7.0 0.0   1   0.0 0.0 7.0, 7.0 -0.52
CC044/UncJ f 8.0 0.0   1   0.0 0.0 8.0, 8.0 -0.67
CC044/UncJ m 44.0 0.0   1   0.0 0.0 44.0, 44.0 -0.31
CC051/TauUncJ f 14.0 0.0   1   0.0 0.0 14.0, 14.0 -0.63
CC051/TauUncJ m 16.333 13.577   3 7.8387 0.8312 2.0, 29.0 -0.47
CC057/UncJ f 11.0 5.6569   2   4.0 0.5143 7.0, 15.0 -0.65
CC059/TauUncJ f 156.5 130.0   4 64.98 0.8304 2.0, 319.0 0.42
CC059/TauUncJ m 740.0 0.0   1   0.0 0.0 740.0, 740.0 3.57
CC061/GeniUncJ f 169.0 0.0   1   0.0 0.0 169.0, 169.0 0.51
CC061/GeniUncJ m 63.0 0.0   1   0.0 0.0 63.0, 63.0 -0.21
CC078/TauUncJ f 400.5 26.163   2   18.5 0.0653 382.0, 419.0 2.21
CC078/TauUncJ m 759.5 372.6   2   263.5 0.4906 496.0, 1023.0 3.67
CC079/TauUncJ f 24.0 12.728   2   9.0 0.5303 15.0, 33.0 -0.56
CC084/TauJ f 70.0 0.0   1   0.0 0.0 70.0, 70.0 -0.22
CC084/TauJ m 36.0 0.0   1   0.0 0.0 36.0, 36.0 -0.36
NOD/ShiLtJ f 41.1 61.34   10 19.398 1.4925 -0.43
NOD/ShiLtJ m 21.2 21.04   5 9.4096 0.9925 2.0, 53.0 -0.44
NZO/HlLtJ f 7.0 6.549   10 2.071 0.9356 -0.68
NZO/HlLtJ m 10.5 8.1275   10 2.5701 0.774 1.0, 25.0 -0.5
PWK/PhJ f 17.6 13.903   5 6.2177 0.79 4.0, 33.0 -0.6
PWK/PhJ m 26.714 41.696   7 15.76 1.5608 -0.41
WSB/EiJ f 23.333 28.729   3 16.586 1.2312 2.0, 56.0 -0.56
WSB/EiJ m 5.4 5.7706   5 2.5807 1.0686 -0.53


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J f 20.2857142857 38.2701582387 95.9826048554 -55.411176284
A/J m 85.4285714286 38.2701582387 161.1254619983 9.7316808589
C57BL/6J f 40.7272727273 30.5290250586 101.112501726 -19.6579562714
C57BL/6J m 9.4545454545 30.5290250586 69.8397744532 -50.9306835441
CC001/UncJ f 56.0 58.4586323289 171.6289103028 -59.6289103028
CC001/UncJ m 94.25 50.6266606673 194.3875737342 -5.8875737342
CC004/TauUncJ f 95.75 35.7984550667 166.557957439 24.942042561
CC004/TauUncJ m 139.4705882353 24.5575375769 188.0444463058 90.8967301648
CC011/UncJ f 77.6666666667 58.4586323289 193.2955769695 -37.9622436362
CC011/UncJ m 159.3333333333 58.4586323289 274.9622436362 43.7044230305
CC018/UncJ f 111.6666666667 58.4586323289 227.2955769695 -3.9622436362
CC018/UncJ m 63.75 50.6266606673 163.8875737342 -36.3875737342
CC019/TauUncJ f 108.75 50.6266606673 208.8875737342 8.6124262658
CC019/TauUncJ m 87.5 71.5969101334 229.115914878 -54.115914878
CC023/GeniUncJ f 31.5 71.5969101334 173.115914878 -110.115914878
CC023/GeniUncJ m 41.3333333333 58.4586323289 156.9622436362 -74.2955769695
CC026/GeniUncJ f 9.4 45.2818618904 98.9657687886 -80.1657687886
CC026/GeniUncJ m 4.3333333333 58.4586323289 119.9622436362 -111.2955769695
CC028/GeniUncJ f 169.0 71.5969101334 310.615914878 27.384085122
CC028/GeniUncJ m 47.0 71.5969101334 188.615914878 -94.615914878
CC078/TauUncJ f 400.5 71.5969101334 542.115914878 258.884085122
CC078/TauUncJ m 759.5 71.5969101334 901.115914878 617.884085122
NOD/ShiLtJ f 41.1 32.0191116075 104.4325624726 -22.2325624726
NOD/ShiLtJ m 21.2 45.2818618904 110.7657687886 -68.3657687886
NZO/HlLtJ f 7.0 32.0191116075 70.3325624726 -56.3325624726
NZO/HlLtJ m 10.5 32.0191116075 73.8325624726 -52.8325624726
PWK/PhJ f 17.6 45.2818618904 107.1657687886 -71.9657687886
PWK/PhJ m 26.7142857143 38.2701582387 102.411176284 -48.9826048554
WSB/EiJ f 23.3333333333 58.4586323289 138.9622436362 -92.2955769695
WSB/EiJ m 5.4 45.2818618904 94.9657687886 -84.1657687886


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
A/J both 52.8571428571 27.0610884077 106.3829274937 -0.6686417794
C57BL/6J both 25.0909090909 21.5872806419 67.7897139994 -17.6078958176
CC001/UncJ both 75.125 38.6667507818 151.6063352577 -1.3563352577
CC004/TauUncJ both 117.6102941176 21.7060016873 160.5439246552 74.6766635801
CC011/UncJ both 118.5 41.3364953387 200.2619865763 36.7380134237
CC018/UncJ both 87.7083333333 38.6667507818 164.189668591 11.2269980757
CC019/TauUncJ both 98.125 43.8439742467 184.8466827271 11.4033172729
CC023/GeniUncJ both 36.4166666667 46.2156067644 127.8293466467 -54.9960133134
CC026/GeniUncJ both 6.8666666667 36.9724854116 79.9968106507 -66.2634773174
CC028/GeniUncJ both 108.0 50.6266606673 208.1375737342 7.8624262658
CC078/TauUncJ both 580.0 50.6266606673 680.1375737342 479.8624262658
NOD/ShiLtJ both 31.15 27.7293640587 85.997607988 -23.697607988
NZO/HlLtJ both 8.75 22.6409309452 53.5328843943 -36.0328843943
PWK/PhJ both 22.1571428571 29.643937103 80.7917021644 -36.4774164501
WSB/EiJ both 14.3666666667 36.9724854116 87.4968106507 -58.7634773174




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA