Project measure / variable:   CSNA03   extinction_inactive_cc_s1

ID, description, units MPD:110409   extinction_inactive_cc_s1   extinction, inactive lever presses (intravenous self administration), CC   [n]  session 1  
cocaine study
Data set, strains CSNA03   CC w/par   53 strains     sex: both     age:
Procedure operant conditioning chamber
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  STRAIN COMPARISON PLOT
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CSNA03 - extinction, inactive lever presses (intravenous self administration), CC session 1



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested50 strains51 strains
Mean of the strain means53.25   n 56.11   n
Median of the strain means34.334   n 29.0   n
SD of the strain means± 60.4 ± 71.76
Coefficient of variation (CV)1.1342 1.2791
Min–max range of strain means0.0   –   352.0   n 0.0   –   307.3   n
Mean sample size per strain3.2   mice 3.5   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 2153.9174 2153.9174 0.2618 0.6094
strain 34 648182.981 19064.2053 2.3169 0.0001
sex:strain 34 339173.6432 9975.6954 1.2124 0.2063
Residuals 224 1843128.1421 8228.2506


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
A/J f 19.778 25.733   9 8.5777 1.3011 -0.55
A/J m 134.3 289.6   7 109.5 2.1565 2.0, 788.0 1.09
C57BL/6J f 36.333 31.827   12 9.1877 0.876 -0.28
C57BL/6J m 19.583 17.239   12 4.9764 0.8803 3.0, 57.0 -0.51
CAST/EiJ f 30.0 0.0   1   0.0 0.0 30.0, 30.0 -0.38
CAST/EiJ m 34.0 24.042   2   17.0 0.7071 17.0, 51.0 -0.31
CC001/UncJ f 39.0 32.741   3 18.903 0.8395 3.0, 67.0 -0.24
CC001/UncJ m 86.25 75.07   4 37.533 0.8703 15.0, 178.0 0.42
CC002/UncJ f 163.3 201.5   3 116.3 1.2338 44.0, 396.0 1.82
CC002/UncJ m 20.0 22.627   2   16.0 1.1314 4.0, 36.0 -0.5
CC003/UncJ f 38.5 26.163   2   18.5 0.6796 20.0, 57.0 -0.24
CC003/UncJ m 32.75 56.19   4 28.096 1.7158 3.0, 117.0 -0.33
CC004/TauUncJ f 34.667 43.641   9 14.547 1.2589 -0.31
CC004/TauUncJ m 116.7 145.0   19 33.262 1.242 14.0, 651.0 0.84
CC005/TauUncJ f 25.5 18.788   4 9.3941 0.7368 8.0, 50.0 -0.46
CC005/TauUncJ m 12.5 9.1924   2   6.5 0.7354 6.0, 19.0 -0.61
CC006/TauUncJ f 66.0 2.8284   2   2.0 0.0429 64.0, 68.0 0.21
CC006/TauUncJ m 33.5 45.962   2   32.5 1.372 1.0, 66.0 -0.32
CC007/UncJ f 139.0 0.0   1   0.0 0.0 139.0, 139.0 1.42
CC007/UncJ m 18.333 17.559   3 10.138 0.9578 -0.53
CC008/GeniUncJ f 12.5 17.678   2   12.5 1.4142 -0.67
CC008/GeniUncJ m 30.5 36.062   2   25.5 1.1824 5.0, 56.0 -0.36
CC009/UncJ f 27.333 24.007   3 13.86 0.8783 1.0, 48.0 -0.43
CC009/UncJ m 3.3333 3.0551   3 1.7638 0.9165 -0.74
CC011/UncJ f 88.0 71.58   3 41.328 0.8134 8.0, 146.0 0.58
CC011/UncJ m 25.0 11.269   3 6.5064 0.4508 18.0, 38.0 -0.43
CC012/GeniUncJ f 78.0 0.0   1   0.0 0.0 78.0, 78.0 0.41
CC012/GeniUncJ m 56.67 4.0415   3 2.3333 0.0713 53.0, 61.0 0.01
CC013/GeniUncJ f 135.3 114.1   3 65.86 0.843 66.0, 267.0 1.36
CC013/GeniUncJ m 46.667 34.269   3 19.785 0.7343 19.0, 85.0 -0.13
CC015/UncJ f 2.0 2.8284   2   2.0 1.4142 -0.85
CC015/UncJ m 50.0 0.0   1   0.0 0.0 50.0, 50.0 -0.09
CC016/GeniUncJ f 12.0 8.4853   2   6.0 0.7071 6.0, 18.0 -0.68
CC016/GeniUncJ m 2.0 1.4142   2   1.0 0.7071 1.0, 3.0 -0.75
CC017/UncJ f 6.6667 3.5119   3 2.0276 0.5268 3.0, 10.0 -0.77
CC017/UncJ m 1.5 2.3805   4 1.1902 1.587 -0.76
CC018/UncJ f 106.3 81.29   3 46.934 0.7645 18.0, 178.0 0.88
CC018/UncJ m 38.2 27.087   5 12.114 0.7091 11.0, 82.0 -0.25
CC019/TauUncJ f 26.25 18.536   4 9.268 0.7061 4.0, 49.0 -0.45
CC019/TauUncJ m 29.0 17.349   3 10.017 0.5983 9.0, 40.0 -0.38
CC020/GeniUncJ f 34.0 0.0   1   0.0 0.0 34.0, 34.0 -0.32
CC023/GeniUncJ f 15.667 16.563   3 9.5627 1.0572 -0.62
CC023/GeniUncJ m 41.333 56.32   3 32.518 1.3627 3.0, 106.0 -0.21
CC024/GeniUncJ f 42.0 59.4   2   42.0 1.4142 -0.19
CC024/GeniUncJ m 47.5 38.891   2   27.5 0.8188 20.0, 75.0 -0.12
CC025/GeniUncJ f 14.5 16.263   2   11.5 1.1216 3.0, 26.0 -0.64
CC025/GeniUncJ m 246.0 0.0   1   0.0 0.0 246.0, 246.0 2.65
CC026/GeniUncJ f 19.8 16.574   5 7.4122 0.8371 3.0, 45.0 -0.55
CC026/GeniUncJ m 5.6667 5.5076   3 3.1798 0.9719 -0.7
CC027/GeniUncJ f 70.0 67.55   4 33.776 0.965 3.0, 149.0 0.28
CC027/GeniUncJ m 14.75 12.038   4 6.0191 0.8161 2.0, 31.0 -0.58
CC028/GeniUncJ f 81.25 25.889   4 12.945 0.3186 56.0, 106.0 0.46
CC028/GeniUncJ m 91.75 69.2   4 34.599 0.7542 12.0, 177.0 0.5
CC029/UncJ f 2.0 0.0   1   0.0 0.0 2.0, 2.0 -0.85
CC029/UncJ m 10.0 0.0   1   0.0 0.0 10.0, 10.0 -0.64
CC030/GeniUncJ f 58.0 0.0   1   0.0 0.0 58.0, 58.0 0.08
CC030/GeniUncJ m 95.0 65.05   2   46.0 0.6848 49.0, 141.0 0.54
CC032/GeniUncJ f 57.0 2.8284   2   2.0 0.0496 55.0, 59.0 0.06
CC032/GeniUncJ m 22.5 13.178   4 6.5891 0.5857 7.0, 38.0 -0.47
CC033/GeniUncJ f 2.0 0.0   1   0.0 0.0 2.0, 2.0 -0.85
CC033/GeniUncJ m 13.0 0.0   1   0.0 0.0 13.0, 13.0 -0.6
CC035/UncJ f 28.667 6.0277   3 3.4801 0.2103 23.0, 35.0 -0.41
CC035/UncJ m 48.5 6.364   2   4.5 0.1312 44.0, 53.0 -0.11
CC036/UncJ f 108.7 56.15   3 32.416 0.5167 65.0, 172.0 0.92
CC036/UncJ m 275.0 24.042   2   17.0 0.0874 258.0, 292.0 3.05
CC037/TauUncJ f 110.0 0.0   1   0.0 0.0 110.0, 110.0 0.94
CC037/TauUncJ m 0.0 0.0   1   0.0 None -0.78
CC040/TauUncJ f 9.5 2.1213   2   1.5 0.2233 8.0, 11.0 -0.72
CC040/TauUncJ m 0.0 0.0   1   0.0 None -0.78
CC041/TauUncJ f 10.0 17.321   3 10.0 1.7321 -0.72
CC041/TauUncJ m 0.66667 2.0151   12 0.58171 3.0226 -0.77
CC043/GeniUncJ m 24.0 0.0   1   0.0 0.0 24.0, 24.0 -0.45
CC044/UncJ f 0.0 0.0   1   0.0 None -0.88
CC044/UncJ m 1.0 0.0   1   0.0 0.0 1.0, 1.0 -0.77
CC051/TauUncJ f 41.5 26.163   2   18.5 0.6304 23.0, 60.0 -0.19
CC051/TauUncJ m 30.667 24.685   3 14.252 0.8049 10.0, 58.0 -0.35
CC057/UncJ f 26.5 19.092   2   13.5 0.7204 13.0, 40.0 -0.44
CC057/UncJ m 27.0 35.355   2   25.0 1.3095 2.0, 52.0 -0.41
CC059/TauUncJ f 74.5 69.51   4 34.757 0.9331 8.0, 164.0 0.35
CC059/TauUncJ m 307.3 391.5   3 226.0 1.2739 35.0, 756.0 3.5
CC060/UncJ m 95.0 0.0   1   0.0 0.0 95.0, 95.0 0.54
CC061/GeniUncJ f 76.0 91.92   2   65.0 1.2095 11.0, 141.0 0.38
CC061/GeniUncJ m 179.5 204.4   2   144.5 1.1385 35.0, 324.0 1.72
CC068/TauUncJ f 0.33333 0.57735   3 0.33333 1.7321 -0.88
CC068/TauUncJ m 0.0 0.0   2   0.0 None -0.78
CC074/UncJ m 23.0 0.0   1   0.0 0.0 23.0, 23.0 -0.46
CC078/TauUncJ f 352.0 366.3   2   259.0 1.0406 93.0, 611.0 4.95
CC078/TauUncJ m 183.0 70.74   3 40.841 0.3866 123.0, 261.0 1.77
CC079/TauUncJ f 22.0 0.0   1   0.0 0.0 22.0, 22.0 -0.52
CC079/TauUncJ m 29.0 22.627   2   16.0 0.7803 13.0, 45.0 -0.38
CC080/TauUncJ f 1.5 2.1213   2   1.5 1.4142 -0.86
CC084/TauJ f 156.0 0.0   1   0.0 0.0 156.0, 156.0 1.7
CC084/TauJ m 160.0 0.0   1   0.0 0.0 160.0, 160.0 1.45
NOD/ShiLtJ f 72.9 128.0   10 40.477 1.7558 0.33
NOD/ShiLtJ m 24.833 18.862   6 7.7003 0.7595 -0.44
NZO/HlLtJ f 20.9 19.273   10 6.0945 0.9221 2.0, 54.0 -0.54
NZO/HlLtJ m 20.667 15.091   9 5.0305 0.7302 3.0, 47.0 -0.49
PWK/PhJ f 40.333 20.106   6 8.2084 0.4985 8.0, 71.0 -0.21
PWK/PhJ m 46.143 63.33   7 23.938 1.3726 9.0, 186.0 -0.14
WSB/EiJ f 28.5 34.648   2   24.5 1.2157 4.0, 53.0 -0.41
WSB/EiJ m 7.8 10.918   5 4.8826 1.3997 1.0, 27.0 -0.67


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J f 19.7777777778 30.2365684314 79.3622909549 -39.8067353993
A/J m 134.2857142857 34.2850459584 201.8482016532 66.7232269182
C57BL/6J f 36.3333333333 26.1856363849 87.9350354169 -15.2683687502
C57BL/6J m 19.5833333333 26.1856363849 71.1850354169 -32.0183687502
CC001/UncJ f 39.0 52.3712727698 142.203404167 -64.203404167
CC001/UncJ m 86.25 45.3548526472 175.6267697657 -3.1267697657
CC002/UncJ f 163.3333333333 52.3712727698 266.5367375004 60.1299291663
CC002/UncJ m 20.0 64.1414477331 146.3978399637 -106.3978399637
CC003/UncJ f 38.5 64.1414477331 164.8978399637 -87.8978399637
CC003/UncJ m 32.75 45.3548526472 122.1267697657 -56.6267697657
CC004/TauUncJ f 34.6666666667 30.2365684314 94.2511798438 -24.9178465105
CC004/TauUncJ m 116.7368421053 20.8102336093 157.7457165588 75.7279676517
CC005/TauUncJ f 25.5 45.3548526472 114.8767697657 -63.8767697657
CC005/TauUncJ m 12.5 64.1414477331 138.8978399637 -113.8978399637
CC006/TauUncJ f 66.0 64.1414477331 192.3978399637 -60.3978399637
CC006/TauUncJ m 33.5 64.1414477331 159.8978399637 -92.8978399637
CC008/GeniUncJ f 12.5 64.1414477331 138.8978399637 -113.8978399637
CC008/GeniUncJ m 30.5 64.1414477331 156.8978399637 -95.8978399637
CC009/UncJ f 27.3333333333 52.3712727698 130.5367375004 -75.8700708337
CC009/UncJ m 3.3333333333 52.3712727698 106.5367375004 -99.8700708337
CC011/UncJ f 88.0 52.3712727698 191.203404167 -15.203404167
CC011/UncJ m 25.0 52.3712727698 128.203404167 -78.203404167
CC013/GeniUncJ f 135.3333333333 52.3712727698 238.5367375004 32.1299291663
CC013/GeniUncJ m 46.6666666667 52.3712727698 149.8700708337 -56.5367375004
CC016/GeniUncJ f 12.0 64.1414477331 138.3978399637 -114.3978399637
CC016/GeniUncJ m 2.0 64.1414477331 128.3978399637 -124.3978399637
CC017/UncJ f 6.6666666667 52.3712727698 109.8700708337 -96.5367375004
CC017/UncJ m 1.5 45.3548526472 90.8767697657 -87.8767697657
CC018/UncJ f 106.3333333333 52.3712727698 209.5367375004 3.1299291663
CC018/UncJ m 38.2 40.5666134514 118.1410131222 -41.7410131222
CC019/TauUncJ f 26.25 45.3548526472 115.6267697657 -63.1267697657
CC019/TauUncJ m 29.0 52.3712727698 132.203404167 -74.203404167
CC023/GeniUncJ f 15.6666666667 52.3712727698 118.8700708337 -87.5367375004
CC023/GeniUncJ m 41.3333333333 52.3712727698 144.5367375004 -61.8700708337
CC024/GeniUncJ f 42.0 64.1414477331 168.3978399637 -84.3978399637
CC024/GeniUncJ m 47.5 64.1414477331 173.8978399637 -78.8978399637
CC026/GeniUncJ f 19.8 40.5666134514 99.7410131222 -60.1410131222
CC026/GeniUncJ m 5.6666666667 52.3712727698 108.8700708337 -97.5367375004
CC027/GeniUncJ f 70.0 45.3548526472 159.3767697657 -19.3767697657
CC027/GeniUncJ m 14.75 45.3548526472 104.1267697657 -74.6267697657
CC028/GeniUncJ f 81.25 45.3548526472 170.6267697657 -8.1267697657
CC028/GeniUncJ m 91.75 45.3548526472 181.1267697657 2.3732302343
CC032/GeniUncJ f 57.0 64.1414477331 183.3978399637 -69.3978399637
CC032/GeniUncJ m 22.5 45.3548526472 111.8767697657 -66.8767697657
CC035/UncJ f 28.6666666667 52.3712727698 131.8700708337 -74.5367375004
CC035/UncJ m 48.5 64.1414477331 174.8978399637 -77.8978399637
CC036/UncJ f 108.6666666667 52.3712727698 211.8700708337 5.4632624996
CC036/UncJ m 275.0 64.1414477331 401.3978399637 148.6021600363
CC041/TauUncJ f 10.0 52.3712727698 113.203404167 -93.203404167
CC041/TauUncJ m 0.6666666667 26.1856363849 52.2683687502 -50.9350354169
CC051/TauUncJ f 41.5 64.1414477331 167.8978399637 -84.8978399637
CC051/TauUncJ m 30.6666666667 52.3712727698 133.8700708337 -72.5367375004
CC057/UncJ f 26.5 64.1414477331 152.8978399637 -99.8978399637
CC057/UncJ m 27.0 64.1414477331 153.3978399637 -99.3978399637
CC059/TauUncJ f 74.5 45.3548526472 163.8767697657 -14.8767697657
CC059/TauUncJ m 307.3333333333 52.3712727698 410.5367375004 204.1299291663
CC061/GeniUncJ f 76.0 64.1414477331 202.3978399637 -50.3978399637
CC061/GeniUncJ m 179.5 64.1414477331 305.8978399637 53.1021600363
CC068/TauUncJ f 0.3333333333 52.3712727698 103.5367375004 -102.8700708337
CC068/TauUncJ m 0.0 64.1414477331 126.3978399637 -126.3978399637
CC078/TauUncJ f 352.0 64.1414477331 478.3978399637 225.6021600363
CC078/TauUncJ m 183.0 52.3712727698 286.203404167 79.796595833
NOD/ShiLtJ f 72.9 28.6849274613 129.4268324736 16.3731675264
NOD/ShiLtJ m 24.8333333333 37.0320821149 97.8091602614 -48.1424935947
NZO/HlLtJ f 20.9 28.6849274613 77.4268324736 -35.6268324736
NZO/HlLtJ m 20.6666666667 30.2365684314 80.2511798438 -38.9178465105
PWK/PhJ f 40.3333333333 37.0320821149 113.3091602614 -32.6424935947
PWK/PhJ m 46.1428571429 34.2850459584 113.7053445104 -21.4196302247
WSB/EiJ f 28.5 64.1414477331 154.8978399637 -97.8978399637
WSB/EiJ m 7.8 40.5666134514 87.7410131222 -72.1410131222


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
A/J both 77.0317460317 22.8566973056 122.0734042768 31.9900877867
C57BL/6J both 27.9583333333 18.5160410574 64.4462467974 -8.5295801307
CC001/UncJ both 62.625 34.6403408982 130.8876354703 -5.6376354703
CC002/UncJ both 91.6666666667 41.4031264786 173.2561215294 10.077211804
CC003/UncJ both 35.625 39.2784545773 113.0275531253 -41.7775531253
CC004/TauUncJ both 75.701754386 18.3529009518 111.8681821696 39.5353266024
CC005/TauUncJ both 19.0 39.2784545773 96.4025531253 -58.4025531253
CC006/TauUncJ both 49.75 45.3548526472 139.1267697657 -39.6267697657
CC008/GeniUncJ both 21.5 45.3548526472 110.8767697657 -67.8767697657
CC009/UncJ both 15.3333333333 37.0320821149 88.3091602614 -57.6424935947
CC011/UncJ both 56.5 37.0320821149 129.4758269281 -16.4758269281
CC013/GeniUncJ both 91.0 37.0320821149 163.975826928 18.0241730719
CC016/GeniUncJ both 7.0 45.3548526472 96.3767697657 -82.3767697657
CC017/UncJ both 4.0833333333 34.6403408982 72.3459688037 -64.179302137
CC018/UncJ both 72.2666666667 33.1225011829 137.5382305568 6.9951027765
CC019/TauUncJ both 27.625 34.6403408982 95.8876354703 -40.6376354703
CC023/GeniUncJ both 28.5 37.0320821149 101.4758269281 -44.4758269281
CC024/GeniUncJ both 44.75 45.3548526472 134.1267697657 -44.6267697657
CC026/GeniUncJ both 12.7333333333 33.1225011829 78.0048972235 -52.5382305568
CC027/GeniUncJ both 42.375 32.0707238665 105.5739199819 -20.8239199819
CC028/GeniUncJ both 86.5 32.0707238665 149.6989199819 23.3010800181
CC032/GeniUncJ both 39.75 39.2784545773 117.1525531253 -37.6525531253
CC035/UncJ both 38.5833333333 41.4031264786 120.172788196 -43.0061215294
CC036/UncJ both 191.8333333333 41.4031264786 273.422788196 110.2438784706
CC041/TauUncJ both 5.3333333333 29.2764314954 63.0257901401 -52.3591234734
CC051/TauUncJ both 36.0833333333 41.4031264786 117.672788196 -45.5061215294
CC057/UncJ both 26.75 45.3548526472 116.1267697657 -62.6267697657
CC059/TauUncJ both 190.9166666667 34.6403408982 259.179302137 122.6540311963
CC061/GeniUncJ both 127.75 45.3548526472 217.1267697657 38.3732302343
CC068/TauUncJ both 0.1666666667 41.4031264786 81.7561215294 -81.422788196
CC078/TauUncJ both 267.5 41.4031264786 349.0894548627 185.9105451373
NOD/ShiLtJ both 48.8666666667 23.4211451963 95.020632112 2.7127012213
NZO/HlLtJ both 20.7833333333 20.8391166677 61.8491250585 -20.2824583918
PWK/PhJ both 43.2380952381 25.2331105996 92.9627395684 -6.4865490923
WSB/EiJ both 18.15 37.9465922192 92.9279705637 -56.6279705637




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA