Project measure / variable:   CSNA03   extinction_inactive_do_s6

ID, description, units MPD:110285   extinction_inactive_do_s6   extinction, inactive lever presses (intravenous self administration), DO   [n]  session 6  
cocaine study
Data set, strains CSNA03   DO population w/par   8 strains     sex: both     age:
Procedure operant conditioning chamber
Ontology mappings

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Plot Options Bins number: (min: 10, max: 40)


Distribution of Individual Animals with Boxplots.





  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means37.127   n 40.215   n
Median of the strain means34.816   n 19.017   n
SD of the strain means± 29.755 ± 44.924
Coefficient of variation (CV)0.8015 1.1171
Min–max range of strain means5.1   –   99.11   n 9.9   –   132.8   n
Mean sample size per strain26.2   mice 23.5   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 50572.4898 50572.4898 0.8695 0.3517
strain 6 590620.6866 98436.7811 1.6924 0.1216
sex:strain 6 50230.7443 8371.7907 0.1439 0.9902
Residuals 381 22160578.0692 58164.2469


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
A/J f 10.571 14.022   7 5.2999 1.3264 -0.89
A/J m 85.86 190.3   7 71.94 2.2169 1.02
C57BL/6J f 49.2 98.88   10 31.268 2.0097 2.0, 324.0 0.41
C57BL/6J m 9.9091 10.368   11 3.126 1.0463 -0.67
CAST/EiJ f 46.0 0.0   1   0.0 0.0 46.0, 46.0 0.3
CAST/EiJ m 29.5 27.577   2   19.5 0.9348 10.0, 49.0 -0.24
J:DO f 99.11 208.1   164 16.254 2.1002 2.08
J:DO m 132.8 325.8   140 27.531 2.4533 2.06
NOD/ShiLtJ f 35.3 58.89   10 18.624 1.6684 -0.06
NOD/ShiLtJ m 15.833 21.236   6 8.6696 1.3412 -0.54
NZO/HlLtJ f 5.1 4.3576   10 1.378 0.8544 -1.08
NZO/HlLtJ m 9.9 7.3704   10 2.3307 0.7445 -0.67
PWK/PhJ f 17.4 13.088   5 5.8532 0.7522 6.0, 39.0 -0.66
PWK/PhJ m 15.714 11.926   7 4.5077 0.759 5.0, 40.0 -0.55
WSB/EiJ f 34.333 43.097   3 24.882 1.2552 1.0, 83.0 -0.09
WSB/EiJ m 22.2 19.791   5 8.851 0.8915 1.0, 43.0 -0.4


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J f 10.5714285714 91.1546933991 189.8006899319 -168.657832789
A/J m 85.8571428571 91.1546933991 265.0864042176 -93.3721185033
C57BL/6J f 49.2 76.265488198 199.1539585655 -100.7539585655
C57BL/6J m 9.9090909091 72.7162898473 152.8845805106 -133.0663986924
J:DO f 99.1097560976 18.832419974 136.13824685 62.0812653451
J:DO m 132.7785714286 20.3828090909 172.8554526245 92.7016902327
NOD/ShiLtJ f 35.3 76.265488198 185.2539585655 -114.6539585655
NOD/ShiLtJ m 15.8333333333 98.4583218937 209.4230614074 -177.7563947407
NZO/HlLtJ f 5.1 76.265488198 155.0539585655 -144.8539585655
NZO/HlLtJ m 9.9 76.265488198 159.8539585655 -140.0539585655
PWK/PhJ f 17.4 107.8556877506 229.4669219349 -194.6669219349
PWK/PhJ m 15.7142857143 91.1546933991 194.9435470747 -163.5149756462
WSB/EiJ f 34.3333333333 139.2410941506 308.1105523117 -239.4438856451
WSB/EiJ m 22.2 107.8556877506 234.2669219349 -189.8669219349


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
A/J both 48.2142857143 64.4561018395 174.9485118093 -78.5199403807
C57BL/6J both 29.5545454545 52.6879575881 133.1501297189 -74.0410388098
J:DO both 115.9441637631 13.8755085358 143.2263261306 88.6620013955
NOD/ShiLtJ both 25.5666666667 62.2705103564 148.003561132 -96.8702277986
NZO/HlLtJ both 7.5 53.9278438753 113.5334609674 -98.5334609674
PWK/PhJ both 16.5571428571 70.6081218927 155.3875317375 -122.2732460233
WSB/EiJ both 28.2666666667 88.063800282 201.4185833544 -144.885250021




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA