Project measure / variable:   CSNA03   extinction_active_do_s3

ID, description, units MPD:110273   extinction_active_do_s3   extinction, active lever presses (intravenous self administration), DO   [n]  session 3  
cocaine study
Data set, strains CSNA03   DO population w/par   8 strains     sex: both     age:
Procedure operant conditioning chamber
Ontology mappings

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Plot Options Bins number: (min: 10, max: 40)


Distribution of Individual Animals with Boxplots.





  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means90.97   n 54.69   n
Median of the strain means99.45   n 43.231   n
SD of the strain means± 68.99 ± 30.884
Coefficient of variation (CV)0.7584 0.5647
Min–max range of strain means15.5   –   226.5   n 17.286   –   111.5   n
Mean sample size per strain40.2   mice 39.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 1883.3537 1883.3537 0.0629 0.8021
strain 6 260199.489 43366.5815 1.4476 0.194
sex:strain 6 217484.6801 36247.4467 1.21 0.2991
Residuals 620 18573096.0797 29956.6066


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
A/J f 17.75 23.975   8 8.4763 1.3507 -1.06
A/J m 17.286 19.19   7 7.253 1.1101 -1.21
C57BL/6J f 226.5 281.2   11 84.79 1.2413 19.0, 1005.0 1.96
C57BL/6J m 42.462 28.445   13 7.8891 0.6699 5.0, 104.0 -0.4
CAST/EiJ f 94.0 0.0   1   0.0 0.0 94.0, 94.0 0.04
CAST/EiJ m 44.0 2.8284   2   2.0 0.0643 42.0, 46.0 -0.35
J:DO f 104.9 151.1   273 9.1479 1.4407 0.2
J:DO m 111.5 204.7   265 12.575 1.8363 1.84
NOD/ShiLtJ f 116.4 180.7   11 54.47 1.5526 3.0, 483.0 0.37
NOD/ShiLtJ m 72.33 88.54   6 36.146 1.224 4.0, 193.0 0.57
NZO/HlLtJ f 40.2 56.2   10 17.772 1.398 -0.74
NZO/HlLtJ m 37.7 41.82   10 13.225 1.1093 7.0, 143.0 -0.55
PWK/PhJ f 112.5 112.6   6 45.967 1.0009 29.0, 324.0 0.31
PWK/PhJ m 80.43 51.38   7 19.42 0.6388 7.0, 138.0 0.83
WSB/EiJ f 15.5 0.70711   2   0.5 0.0456 15.0, 16.0 -1.09
WSB/EiJ m 31.8 18.377   5 8.2183 0.5779 11.0, 54.0 -0.74


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J f 17.75 61.1929393192 137.9205462584 -102.4205462584
A/J m 17.2857142857 65.4180038348 145.753432023 -111.1820034515
C57BL/6J f 226.5454545455 52.185513995 329.027240734 124.0636683569
C57BL/6J m 42.4615384615 48.0036910281 136.7310708201 -51.807993897
J:DO f 104.9157509158 10.4752641797 125.4870493806 84.3444524509
J:DO m 111.4716981132 10.6322057173 132.3511979901 90.5921982363
NOD/ShiLtJ f 116.3636363636 52.185513995 218.8454225522 13.8818501751
NOD/ShiLtJ m 72.3333333333 70.6595199768 211.0943277952 -66.4276611286
NZO/HlLtJ f 40.2 54.7326288243 147.6838041308 -67.2838041308
NZO/HlLtJ m 37.7 54.7326288243 145.1838041308 -69.7838041308
PWK/PhJ f 112.5 70.6595199768 251.2609944619 -26.2609944619
PWK/PhJ m 80.4285714286 65.4180038348 208.8962891658 -48.0391463087
WSB/EiJ f 15.5 122.3858786383 255.8410925168 -224.8410925168
WSB/EiJ m 31.8 77.4036259876 183.8050535373 -120.2050535373


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
A/J both 17.5178571429 44.7886454591 105.4736907877 -70.437976502
C57BL/6J both 134.5034965035 35.4530754069 204.1261602551 64.8808327519
J:DO both 108.1937245145 7.4628238297 122.8491999046 93.5382491244
NOD/ShiLtJ both 94.3484848485 43.920654692 180.5997603238 8.0972093732
NZO/HlLtJ both 38.95 38.7018129938 114.9525267686 -37.0525267686
PWK/PhJ both 96.4642857143 48.1463471852 191.0139658891 1.9146055394
WSB/EiJ both 23.65 72.4044622349 165.8377078487 -118.5377078487




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA