Project measure / variable:   Deschepper1   BP


  STRAIN COMPARISON PLOT
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Deschepper1 - systolic blood pressure



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested13 strains13 strains
Mean of the strain means120   mmHg 119   mmHg
Median of the strain means120   mmHg 117   mmHg
SD of the strain means± 9.56 ± 9.67
Coefficient of variation (CV)0.0795 0.0816
Min–max range of strain means102   –   135   mmHg 103   –   139   mmHg
Mean sample size per strain9.7   mice 9.1   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 255.6917 255.6917 3.0446 0.0824
strain 12 14356.9211 1196.4101 14.2459 < 0.0001
sex:strain 12 5593.1758 466.098 5.5499 < 0.0001
Residuals 216 18140.2307 83.9825


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 115.0 11.5   8 4.06 0.1 104.0, 140.0 -0.56
129S1/SvImJ m 126.0 10.7   9 3.57 0.0849 116.0, 150.0 0.76
A/J f 113.0 7.78   10 2.46 0.0691 104.0, 126.0 -0.76
A/J m 110.0 6.34   9 2.11 0.0579 103.0, 124.0 -0.89
AKR/J f 130.0 10.3   10 3.26 0.0793 112.0, 149.0 1.01
AKR/J m 117.0 7.3   10 2.31 0.0626 105.0, 125.0 -0.17
BALB/cByJ f 120.0 10.7   10 3.39 0.0895 105.0, 137.0 -0.03
BALB/cByJ m 115.0 10.5   7 3.95 0.0911 97.5, 126.0 -0.37
C3H/HeJ f 102.0 4.92   10 1.56 0.0481 93.5, 110.0 -1.91
C3H/HeJ m 103.0 5.24   9 1.75 0.0506 96.7, 113.0 -1.61
C57BL/6J f 129.0 6.37   10 2.01 0.0494 120.0, 139.0 0.91
C57BL/6J m 114.0 9.99   10 3.16 0.0878 100.0, 133.0 -0.48
C57L/J f 111.0 14.6   10 4.61 0.131 89.5, 132.0 -0.97
C57L/J m 110.0 4.63   7 1.75 0.0421 103.0, 115.0 -0.89
CAST/EiJ f 114.0 9.08   8 3.21 0.0795 104.0, 134.0 -0.66
CAST/EiJ m 139.0 12.2   8 4.33 0.0881 124.0, 156.0 2.11
CBA/J f 116.0 7.41   10 2.34 0.064 102.0, 126.0 -0.45
CBA/J m 114.0 9.42   10 2.98 0.0823 102.0, 129.0 -0.48
DBA/2J f 131.0 7.28   10 2.3 0.0556 121.0, 146.0 1.12
DBA/2J m 122.0 7.66   10 2.42 0.0631 112.0, 134.0 0.35
FVB/NJ f 126.0 9.51   10 3.01 0.0753 110.0, 139.0 0.6
FVB/NJ m 122.0 10.4   10 3.3 0.0852 112.0, 150.0 0.35
PWK/PhJ f 135.0 11.0   10 3.47 0.0813 121.0, 154.0 1.54
PWK/PhJ m 132.0 12.3   8 4.34 0.0933 120.0, 155.0 1.38
SJL/J f 122.0 5.77   9 1.92 0.0471 113.0, 132.0 0.18
SJL/J m 118.0 7.03   10 2.22 0.0598 105.0, 130.0 -0.06


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 114.75 3.24 121.1361 108.3639
129S1/SvImJ m 126.2222 3.0547 132.2431 120.2013
A/J f 112.6 2.898 118.3119 106.8881
A/J m 109.6667 3.0547 115.6876 103.6458
AKR/J f 130.1 2.898 135.8119 124.3881
AKR/J m 116.7 2.898 122.4119 110.9881
BALB/cByJ f 119.8 2.898 125.5119 114.0881
BALB/cByJ m 114.7857 3.4637 121.6128 107.9587
C3H/HeJ f 102.45 2.898 108.1619 96.7381
C3H/HeJ m 103.4444 3.0547 109.4653 97.4235
C57BL/6J f 128.9 2.898 134.6119 123.1881
C57BL/6J m 113.8 2.898 119.5119 108.0881
C57L/J f 111.05 2.898 116.7619 105.3381
C57L/J m 110.1429 3.4637 116.9699 103.3158
CAST/EiJ f 114.125 3.24 120.5111 107.7389
CAST/EiJ m 139.0 3.24 145.3861 132.6139
CBA/J f 115.8 2.898 121.5119 110.0881
CBA/J m 114.5 2.898 120.2119 108.7881
DBA/2J f 130.9 2.898 136.6119 125.1881
DBA/2J m 121.5 2.898 127.2119 115.7881
FVB/NJ f 126.3 2.898 132.0119 120.5881
FVB/NJ m 122.3 2.898 128.0119 116.5881
PWK/PhJ f 134.8 2.898 140.5119 129.0881
PWK/PhJ m 131.5 3.24 137.8861 125.1139
SJL/J f 122.4444 3.0547 128.4653 116.4235
SJL/J m 117.5 2.898 123.2119 111.7881


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 120.4861 2.2265 124.8746 116.0977
A/J both 111.1333 2.1053 115.283 106.9837
AKR/J both 123.4 2.0492 127.4389 119.3611
BALB/cByJ both 117.2929 2.2581 121.7436 112.8422
C3H/HeJ both 102.9472 2.1053 107.0968 98.7976
C57BL/6J both 121.35 2.0492 125.3889 117.3111
C57L/J both 110.5964 2.2581 115.0471 106.1457
CAST/EiJ both 126.5625 2.291 131.0782 122.0468
CBA/J both 115.15 2.0492 119.1889 111.1111
DBA/2J both 126.2 2.0492 130.2389 122.1611
FVB/NJ both 124.3 2.0492 128.3389 120.2611
PWK/PhJ both 133.15 2.1735 137.4339 128.8661
SJL/J both 119.9722 2.1053 124.1218 115.8226




  GWAS USING LINEAR MIXED MODELS