MPD: JaxKOMP-EAP genotype: Aatf<sup>em1(IMPC)J</sup>/Mmjax -/+

JaxKOMP-EAP effect sizes: Aatf^em1(IMPC)J/Mmjax -/+ Gene Aatf

MULTIPLE (NUMERIC) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

Procedure	JaxKOMP-EAP Trait	Trait Effect	Trait Effect SE	Trait Effect RankZ	Adjusted p-value	Unadjusted p-value
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 6 kHz pip	-0.66145	5.3589	-0.47704	0.971	0.904
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 12 kHz pip	-5.9875	7.8079	-1.1673	0.826	0.459
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 18 kHz pip	4.3534	4.8904	0.68030	0.737	0.392
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 24 kHz pip	5.3296	4.7906	0.73447	0.675	0.292
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 30 kHz pip	2.9741	4.0821	0.43843	0.782	0.481
body composition	body length	0.010634	0.032693	0.34822	0.893	0.748
body composition	body weight (at time of DXA)	-0.076358	0.68768	0.025246	0.965	0.913
body composition	bone area, whole body scan, head excluded	0.036446	0.13391	0.33376	0.909	0.788
body composition	bone mineral content of whole body scan, head excluded	0.0068047	0.0086092	0.51471	0.700	0.438
body composition	bone mineral content to body weight ratio	0.00066459	0.00046280	1.0515	0.417	0.165
body composition	bone mineral density of whole body scan, head excluded	0.0015296	0.00055826	1.5881	0.107	0.0123
body composition	fat tissue mass of whole body scan, head excluded	-0.17312	0.32791	-0.30788	0.798	0.603
body composition	fat tissue mass to body weight ratio	-0.0055078	0.0098473	-0.19510	0.771	0.582
body composition	lean tissue mass of whole body scan, head excluded	-0.20693	0.26915	-0.60578	0.730	0.451
body composition	lean tissue mass to body weight ratio	0.018997	0.0078872	0.94976	0.145	0.0248
body composition	percent fat, whole body scan, head excluded	-0.71550	0.90928	-0.29645	0.670	0.440
body composition	ratio of soft-tissue attenuation coefficients	0.00077228	0.0010024	0.28998	0.680	0.450
body composition	tissue area	-0.24360	0.34306	-0.63136	0.764	0.485
body composition	total tissue mass, whole body scan, head excluded	-0.095474	0.35104	-0.44877	0.893	0.788
clinical blood chemistry	alanine transaminase (plasma ALT)	3.2222	2.7846	0.28213	0.633	0.262
clinical blood chemistry	albumin (plasma Alb)	-0.97827	0.35311	-1.2186	0.137	0.0126
clinical blood chemistry	alkaline phosphatase (plasma ALP)	2.4562	3.7769	-0.11289	0.737	0.524
clinical blood chemistry	aspartate transaminase (plasma AST)	5.8038	3.0312	0.28599	0.344	0.0716
clinical blood chemistry	aspartate transaminase to alanine transaminase ratio (plasma AST:ALT)	0.050537	0.10892	0.18558	0.888	0.648
clinical blood chemistry	blood urea nitrogen (BUN)	-0.20370	1.5832	-0.10842	0.948	0.899
clinical blood chemistry	calcium (plasma Ca)	-0.14888	0.062880	-0.73976	0.141	0.0293
clinical blood chemistry	creatinine (plasma)	0.035370	0.018811	0.96254	0.256	0.0763
clinical blood chemistry	glucose (plasma GLU, no fast)	-40.074	10.673	-1.0395	0.0129	0.00145
clinical blood chemistry	HDL cholesterol (plasma HDL)	-3.0259	3.1917	-0.97158	0.648	0.356
clinical blood chemistry	HDL cholesterol to total cholesterol ratio	0.022629	0.013607	1.0998	0.420	0.114
clinical blood chemistry	phosphorus (plasma phosphate)	-0.30438	0.41164	-0.54198	0.730	0.469
clinical blood chemistry	total bilirubin (plasma TBIL)	0.010780	0.0082452	0.67717	0.552	0.208
clinical blood chemistry	total cholesterol (plasma CHOL, no fast)	-6.4607	4.1665	-1.2293	0.414	0.138
clinical blood chemistry	total protein (plasma TP)	-0.60811	0.70232	-0.53063	0.652	0.398
clinical blood chemistry	triglyceride (plasma TG, no fast)	75.336	38.028	2.6071	0.263	0.0640
ERG v2.0	left eye a-wave amplitude (Photopic)	-2.9672	0.98233	-0.81989	0.205	0.00735
ERG v2.0	left eye a-wave amplitude (Scotopic)	-37.292	13.701	-1.2509	0.219	0.0135
ERG v2.0	left eye a-wave implicit timing (Photopic)	1.7716	1.2983	1.0294	0.743	0.188
ERG v2.0	left eye a-wave implicit timing (Scotopic)	1.2603	0.43152	1.1293	0.160	0.00877
ERG v2.0	left eye b-wave amplitude (Photopic)	12.434	2.5631	0.80460	0.00905	0.000128
ERG v2.0	left eye b-wave amplitude (Scotopic)	99.577	36.135	1.3537	0.229	0.0130
ERG v2.0	left eye b-wave implicit timing (Photopic)	-5.0117	2.4915	-0.92443	0.325	0.0595
ERG v2.0	left eye b-wave implicit timing (Scotopic)	6.0326	5.0515	0.59201	0.714	0.247
ERG v2.0	left eye c-wave amplitude (Scotopic)	53.783	19.658	1.2168	0.221	0.0131
ERG v2.0	left eye c-wave implicit timing (Scotopic)	81.784	56.596	0.65393	0.577	0.165
ERG v2.0	left eye FO-like wave amplitude (Scotopic)	-84.107	25.904	-1.1941	0.113	0.00424
ERG v2.0	left eye FO-like wave implicit timing (Scotopic)	-183.00	149.85	-0.55306	0.761	0.237
ERG v2.0	right eye a-wave amplitude (Photopic)	-1.0674	0.94246	-0.34769	0.731	0.272
ERG v2.0	right eye a-wave amplitude (Scotopic)	-11.342	16.048	-0.64714	0.833	0.489
ERG v2.0	right eye a-wave implicit timing (Photopic)	-0.029891	1.9296	-0.068918	0.997	0.988
ERG v2.0	right eye a-wave implicit timing (Scotopic)	0.026370	0.64299	0.038658	0.982	0.968
ERG v2.0	right eye b-wave amplitude (Photopic)	6.8800	3.2918	0.41270	0.363	0.0511
ERG v2.0	right eye b-wave amplitude (Scotopic)	31.466	42.308	0.78201	0.923	0.467
ERG v2.0	right eye b-wave implicit timing (Photopic)	-1.0238	1.2827	-0.071522	0.736	0.435
ERG v2.0	right eye b-wave implicit timing (Scotopic)	6.4745	5.2932	0.74522	0.763	0.237
ERG v2.0	right eye c-wave amplitude (Scotopic)	27.945	19.509	0.89943	0.562	0.169
ERG v2.0	right eye c-wave implicit timing (Scotopic)	17.450	42.518	0.28190	0.886	0.686
ERG v2.0	right eye FO-like wave amplitude (Scotopic)	-26.858	22.835	-0.70236	0.653	0.254
ERG v2.0	right eye FO-like wave implicit timing (Scotopic)	147.03	126.09	0.69534	0.801	0.258
glucose tolerance test	amount glucose injected	-6.9706	1.8180	-1.4824	0.261	0.0313
glucose tolerance test	plasma glucose, 0min	1.0969	3.5052	-0.12248	0.885	0.775
glucose tolerance test	plasma glucose, 15min	-49.646	20.793	-1.2528	0.365	0.0969
glucose tolerance test	plasma glucose, 30min	-34.975	28.032	-0.95507	0.633	0.301
glucose tolerance test	plasma glucose, 60min	-21.318	16.258	-0.79030	0.609	0.281
glucose tolerance test	plasma glucose, 120min	-5.0726	7.7242	-0.49905	0.800	0.558
grip strength	body weight (at time of grip strength test)	-0.57859	0.53778	-0.31711	0.488	0.295
grip strength	forelimb and hindlimb grip strength (mean of trials), average	5.7283	4.6791	0.65547	0.442	0.235
grip strength	forelimb and hindlimb grip strength (mean of trials), average normalized to bw	0.33246	0.17393	0.68455	0.210	0.0712
grip strength	forelimb and hindlimb grip strength by trial, trial1	11.826	7.8722	1.0412	0.408	0.149
grip strength	forelimb and hindlimb grip strength by trial, trial2	2.4694	9.3587	0.38235	0.895	0.795
grip strength	forelimb and hindlimb grip strength by trial, trial3	0.62781	6.5499	0.24645	0.970	0.925
grip strength	forelimb grip strength (mean of trials), average	-2.8973	4.7511	-0.10476	0.773	0.549
grip strength	forelimb grip strength (mean of trials), average normalized to bw	-0.13967	0.23038	-0.13694	0.774	0.552
grip strength	forelimb grip strength by trial, trial1	3.4438	5.6039	0.64828	0.804	0.546
grip strength	forelimb grip strength by trial, trial2	-8.3497	6.3673	-0.68088	0.534	0.205
grip strength	forelimb grip strength by trial, trial3	-5.1565	6.8235	-0.32820	0.746	0.459
heart weight	heart weight, normalized to body weight	0.33133	0.11477	0.67746	0.0469	0.00703
heart weight	heart weight, weight	6.0858	3.2477	0.42086	0.223	0.0704
hematology	basophil differential (percent of total WBC)	0.024074	0.061564	0.39287	0.915	0.700
hematology	eosinophil differential (percent of total WBC)	0.31296	0.23444	0.93835	0.592	0.199
hematology	hematocrit (HCT)	-0.33148	0.66206	-0.68223	0.805	0.623
hematology	lymphocyte differential (percent of total WBC)	-0.77229	2.2152	-0.37342	0.873	0.732
hematology	mean corpuscular hemoglobin (CHr)	0.083333	0.067140	0.69591	0.463	0.230
hematology	mean platelet volume (MPV)	0.12233	0.031388	0.60010	0.0113	0.00116
hematology	mean RBC corpuscular hemoglobin concentration (MCHC)	0.011111	0.12407	0.043846	0.972	0.930
hematology	mean RBC corpuscular volume (MCV)	0.27778	0.21402	0.52158	0.424	0.211
hematology	measured hemoglobin (mHGB)	-0.088921	0.21400	-0.46550	0.846	0.683
hematology	monocyte differential (percent of total WBC)	0.61649	0.38737	1.7724	0.484	0.130
hematology	neutrophil differential (percent of total WBC)	-0.24359	1.8510	-0.099939	0.950	0.897
hematology	platelet count (PLT; units per volume x 10³)	-31.535	36.297	-0.37489	0.725	0.397
hematology	RBC corpuscular distribution width (RDW)	0.37000	0.26258	1.1654	0.426	0.176
hematology	red blood cell count (RBC; per volume x 10⁶)	-0.19522	0.14068	-1.1039	0.447	0.183
hematology	reticulocyte count (Retic; units per volume x 10⁹)	-2.2778	18.636	-0.0089278	0.975	0.904
hematology	reticulocyte differential (percent of total RBC)	0.034074	0.17711	0.36485	0.937	0.850
hematology	white blood cell count (WBC; units per volume x 10³)	-0.19222	1.1569	0.042382	0.928	0.870
holeboard	number of hole pokes by individual hole number, 20 min test, 1	1.1481	0.87735	1.0770	0.685	0.199
holeboard	number of hole pokes by individual hole number, 20 min test, 2	0.37785	0.48931	0.73122	0.844	0.445
holeboard	number of hole pokes by individual hole number, 20 min test, 3	0.24972	0.45501	0.49652	0.908	0.586
holeboard	number of hole pokes by individual hole number, 20 min test, 4	-0.040614	0.75111	0.053196	0.987	0.957
holeboard	number of hole pokes by individual hole number, 20 min test, 5	0.57356	0.68851	0.97147	0.837	0.410
holeboard	number of hole pokes by individual hole number, 20 min test, 6	-0.47897	0.63824	-1.3522	0.898	0.458
holeboard	number of hole pokes by individual hole number, 20 min test, 7	0.014244	0.30971	0.038040	1.00	0.964
holeboard	number of hole pokes by individual hole number, 20 min test, 8	0.30158	0.44841	0.63527	0.874	0.505
holeboard	number of hole pokes by individual hole number, 20 min test, 9	0.24082	0.44815	0.52092	0.920	0.594
holeboard	number of hole pokes by individual hole number, 20 min test, 10	-0.28377	0.37290	-0.72747	0.878	0.451
holeboard	number of hole pokes by individual hole number, 20 min test, 11	0.40467	0.36755	0.96025	0.807	0.278
holeboard	number of hole pokes by individual hole number, 20 min test, 12	0.21723	0.67758	0.48000	0.952	0.750
holeboard	number of hole pokes by individual hole number, 20 min test, 13	2.2636	0.99651	1.9734	0.378	0.0289
holeboard	number of hole pokes by individual hole number, 20 min test, 14	0.11645	0.49717	0.27501	0.956	0.816
holeboard	number of hole pokes by individual hole number, 20 min test, 15	0.50482	0.43995	0.87626	0.716	0.258
holeboard	number of hole pokes by individual hole number, 20 min test, 16	0.26142	1.1061	0.27150	0.948	0.814
holeboard	total number of hole pokes, 20 min test	5.6636	5.1047	0.86150	0.564	0.274
light / dark	latency to enter dark zone, 20 min test	-56.160	40.410	-1.1445	0.605	0.173
light / dark	number of transitions between light and dark zones, 20 min test	4.2023	5.6445	0.47871	0.734	0.461
light / dark	percentage of total time in dark zone, 20 min test	-1.4462	4.3555	-0.14108	0.914	0.742
light / dark	percentage of total time in light zone, 20 min test	1.4458	4.3553	0.13698	0.916	0.742
light / dark	time mobile in dark zone, 20 min test	7.6317	4.7768	0.38955	0.385	0.119
light / dark	time mobile in light zone, 20 min test	0.57567	3.7942	-0.20283	0.946	0.880
light / dark	time spent in dark zone, 20 min test	27.442	51.754	0.62030	0.872	0.599
light / dark	time spent in light zone, 20 min test	-27.443	51.754	-0.62030	0.872	0.599
open field	average speed in center of arena, 20 min test	0.053026	0.34315	0.00067130	0.963	0.878
open field	average speed in periphery of arena, 20 min test	0.42630	0.16911	1.0412	0.0776	0.0158
open field	distance traveled habituation ratio, 20 min test	-8.2966	7.5431	-0.71682	0.606	0.278
open field	distance traveled in center of arena, 20 min test	176.26	111.30	0.75020	0.336	0.121
open field	distance traveled in periphery of arena, 20 min test	304.84	194.21	0.74665	0.325	0.124
open field	distance traveled slope, 20 min test	-7.5209	6.6738	-0.65066	0.594	0.266
open field	distance traveled, 20 min test, 1st 5min	173.85	75.956	0.99384	0.132	0.0274
open field	distance traveled, 20 min test, 2nd 5min	99.727	66.343	0.59363	0.350	0.141
open field	distance traveled, 20 min test, 3rd 5min	99.007	63.272	0.64074	0.328	0.126
open field	distance traveled, 20 min test, 4th 5min	103.11	59.560	0.63909	0.273	0.0911
open field	number of clockwise revolution episodes, 20 min test	2.2660	1.1817	0.85355	0.319	0.0623
open field	number of counter-clockwise revolution episodes, 20 min test	0.43027	1.7953	-0.21443	0.914	0.812
open field	number of rears in 5 min bins, 20 min test, 1st 5min	6.2457	2.4606	1.4508	0.112	0.0151
open field	number of rears in 5 min bins, 20 min test, 2nd 5min	1.5652	4.1570	0.034243	0.860	0.709
open field	number of rears in 5 min bins, 20 min test, 3rd 5min	1.6762	3.0380	0.093446	0.783	0.584
open field	number of rears in 5 min bins, 20 min test, 4th 5min	1.2708	4.0250	-0.073237	0.885	0.754
open field	percentage of total time in center of arena, 20 min test	5.5795	3.4537	1.0071	0.406	0.114
open field	percentage of total time in center of arena, slope, 20 min test	1.3903	1.5383	0.89727	0.801	0.372
open field	percentage of total time in center, habituation ratio, 20 min test	1.6957	1.6830	1.0206	0.786	0.320
open field	percentage of total time in corners of arena, 20 min test	-7.4780	2.8569	-1.0983	0.128	0.0124
open field	percentage of total time in corners, habituation ratio, 20 min test	-0.53323	1.8379	-0.53073	0.959	0.773
open field	percentage of total time in corners, slope, 20 min test	-0.47005	1.6621	-0.49398	0.950	0.779
open field	permanence time in center of arena, 20 min test	66.944	41.444	1.0071	0.406	0.114
open field	permanence time in corners of arena, 20 min test	-89.751	34.284	-1.0983	0.128	0.0124
open field	permanence time in periphery of arena, 20 min test	-66.945	41.444	-1.0071	0.406	0.114
open field	total distance traveled, 20 min test	485.36	227.06	0.85780	0.140	0.0387
open field	total number of rears, 20 min test	10.767	11.956	0.38887	0.621	0.373
open field	whole arena average speed, 20 min test	0.40404	0.18914	0.85586	0.141	0.0388
open field	whole arena resting time, 20 min test	-6.9892	19.298	0.36580	0.838	0.719
open field	whole arena time spent mobile, 20 min test	10.167	4.0744	-0.059781	0.0786	0.0169
open field	whole arena time spent vertical, 20 min test	6.0975	7.4273	0.38019	0.708	0.417
SHIRPA	locomotor activity (number of squares in the arena the mouse moves into with all four paws in first 30 s of test)	-0.68128	1.7636	-0.11891	0.886	0.703
startle / PPI	average baseline movement during background noise	0.35039	1.2440	0.31551	0.963	0.780
startle / PPI	average of each corrected maximum percent pre-pulse inhibition value	0.10891	0.059700	0.89850	0.384	0.0788
startle / PPI	average of each corrected percent pre-pulse inhibition value	0.079669	0.052285	0.70969	0.476	0.139
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-6.6421	8.4808	-0.67845	0.879	0.440
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	14.180	5.8662	1.4131	0.265	0.0224
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	12.126	5.8202	1.1174	0.243	0.0465
startle / PPI	average startle response to full pulse (120 dB)	-47.055	36.696	-0.65396	0.440	0.210
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-29.567	39.673	-0.41133	0.685	0.462
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-65.500	34.691	-1.0325	0.215	0.0694
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-55.373	31.742	-1.0277	0.271	0.0920
startle / PPI	average startle response to pre-pulse, 74dB sound pressure level	1.0807	1.2065	0.75081	0.821	0.378
startle / PPI	average startle response to pre-pulse, 78dB sound pressure level	-1.2428	1.5243	-0.85528	0.861	0.422
startle / PPI	average startle response to pre-pulse, 82dB sound pressure level	2.9313	2.3941	1.0301	0.674	0.231
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-0.046624	0.096688	-0.39310	0.922	0.633
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	0.13370	0.066879	1.0175	0.320	0.0554
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	0.12949	0.069842	0.80930	0.252	0.0739
startle / PPI	corrected average startle response to full pulse (120 dB) minus average baseline movement during background noise	-39.639	36.813	-0.53520	0.534	0.290
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 74dB sound pressure level	-30.495	39.553	-0.41744	0.669	0.447
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 78dB sound pressure level	-64.108	34.893	-1.0112	0.231	0.0768
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 82dB sound pressure level	-58.273	31.863	-1.0616	0.237	0.0781
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-0.020248	0.11428	-0.14836	0.975	0.861
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	0.16264	0.076230	1.1907	0.278	0.0418
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	0.16805	0.073948	0.99005	0.161	0.0309
startle / PPI	corrected maximum startle response to full pulse (120 dB) minus maximum baseline movement during background noise	-148.68	135.79	-0.55144	0.528	0.283
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 74dB sound pressure level	-141.09	151.09	-0.55307	0.588	0.358
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 78dB sound pressure level	-261.52	136.82	-1.1253	0.210	0.0662
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 82dB sound pressure level	-233.88	126.42	-1.1548	0.226	0.0749
startle / PPI	maximum baseline movement during background noise	-1.2281	3.3190	-0.30082	0.938	0.714
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-4.0064	10.415	-0.36151	0.953	0.703
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	17.329	6.9176	1.5424	0.226	0.0183
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	15.324	6.3138	1.2531	0.154	0.0219
startle / PPI	maximum startle response to full pulse (120 dB)	-148.02	135.31	-0.55471	0.525	0.283
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-138.23	151.46	-0.54006	0.595	0.369
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-265.27	136.34	-1.1520	0.202	0.0618
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-225.17	126.24	-1.1096	0.249	0.0853
startle / PPI	maximum startle response to pre-pulse, 74dB sound pressure level	3.2237	2.9645	0.92182	0.746	0.286
startle / PPI	maximum startle response to pre-pulse, 78dB sound pressure level	-3.5789	3.1854	-1.0019	0.751	0.270
startle / PPI	maximum startle response to pre-pulse, 82dB sound pressure level	8.3628	6.0047	1.1044	0.544	0.174

MULTIPLE (CATEGORICAL) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

In this plot, data points are the computed genotype effect % vs. C57BL/6NJ controls, for all measured categorical phenotypes in JaxKOMP-EAP

Dimensions Width: × Height: px

Plot Options Group by Procedure

Significance Threshold p-Value Threshold

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Procedure	JaxKOMP-EAP Trait	Trait Effect	P-value

eye morphology	anterior chamber depth	1.0 %	1.0
eye morphology	bulging eye	1.0 %	1.00
eye morphology	cornea	3.0 %	1.00
eye morphology	cornea opacity	3.0 %	1.0
eye morphology	cornea vascularization	2.0 %	1.0
eye morphology	corneal deposits	1.0 %	1.00
eye morphology	corneal mineralization	1.0 %	1.0
eye morphology	corneal scleralization	2.0 %	1.0
eye morphology	corneal ulcer	1.0 %	1.0
eye morphology	eye closure	1.0 %	1.00
eye morphology	eye hemorrhage or blood presence	1.0 %	1.0
eye morphology	eyelid morphology	1.0 %	1.00
eye morphology	eyes (present, absent)	0.0 %	1.00
eye morphology	fusion between cornea and lens	3.0 %	1.0
eye morphology	iris pigmentation	2.0 %	1.0
eye morphology	iris transillumination	1.0 %	1.00
eye morphology	irispupil	3.0 %	1.0
eye morphology	lacrimation	3.0 %	1.00
eye morphology	lens	9.0 %	1.00
eye morphology	lens opacity	7.0 %	1.00
eye morphology	narrow eye opening	1.0 %	1.00
eye morphology	optic disc	3.0 %	1.00
eye morphology	persistence of hyaloid vascular system	9.0 %	1.00
eye morphology	pupil dilation	2.0 %	1.00
eye morphology	pupil light response	2.0 %	1.0
eye morphology	pupil position	4.0 %	1.0
eye morphology	pupil shape	3.0 %	1.0
eye morphology	retina	5.0 %	0.551
eye morphology	retinal blood vessels	3.0 %	1.00
eye morphology	retinal blood vessels pattern	4.0 %	1.00
eye morphology	retinal blood vessels structure	3.0 %	1.0
eye morphology	retinal pigmentation	13.0 %	1.00
eye morphology	retinal structure	3.0 %	1.00
eye morphology	synechia	3.0 %	1.00
eye morphology	vitreous	3.0 %	1.0
SHIRPA	activity body position	1.0 %	1.00
SHIRPA	aggression	1.0 %	1.00
SHIRPA	body length	0.0 %	1.0
SHIRPA	body position	0.0 %	1.00
SHIRPA	body thickness	0.0 %	1.00
SHIRPA	coat color abdomen	4.0 %	1.00
SHIRPA	coat color back	0.0 %	1.00
SHIRPA	coat color head	0.0 %	1.0
SHIRPA	coat color pattern abdomen	13.0 %	0.00403
SHIRPA	coat color pattern back	0.0 %	1.00
SHIRPA	coat color pattern head	0.0 %	1.0
SHIRPA	coat hair abdomen texture appearance	2.0 %	1.0
SHIRPA	coat hair back texture appearance	0.0 %	1.0
SHIRPA	coat hair distribution abdomen	1.0 %	1.0
SHIRPA	coat hair distribution back	0.0 %	1.00
SHIRPA	coat hair distribution head	1.0 %	1.0
SHIRPA	coat hair head texture appearance	0.0 %	1.0
SHIRPA	contact righting	5.0 %	1.00
SHIRPA	ear morphology	0.0 %	1.0
SHIRPA	fat distribution	0.0 %	1.0
SHIRPA	forelimb digit number	0.0 %	1.0
SHIRPA	forelimb digit position	0.0 %	1.0
SHIRPA	forelimb digit shape	0.0 %	1.0
SHIRPA	forelimb digit size	0.0 %	1.0
SHIRPA	forelimb footpads	0.0 %	1.0
SHIRPA	forelimb nail length	0.0 %	1.0
SHIRPA	forelimb nail number	0.0 %	1.0
SHIRPA	forelimb nail position	0.0 %	1.0
SHIRPA	forelimb nail shape	0.0 %	1.0
SHIRPA	forelimbs position	0.0 %	1.0
SHIRPA	forelimbs shape	0.0 %	1.0
SHIRPA	forelimbs size	0.0 %	1.0
SHIRPA	forepaw position	0.0 %	1.0
SHIRPA	forepaw shape	0.0 %	1.0
SHIRPA	forepaw size	0.0 %	1.0
SHIRPA	gait (fluidity)	0.0 %	1.0
SHIRPA	genitalia morphology	0.0 %	1.00
SHIRPA	genitalia presence	0.0 %	1.0
SHIRPA	genitalia size	0.0 %	1.00
SHIRPA	head bobbing	0.0 %	1.0
SHIRPA	head morphology	0.0 %	1.0
SHIRPA	head size	0.0 %	1.0
SHIRPA	hindlimb digit number	0.0 %	1.0
SHIRPA	hindlimb digit position	0.0 %	1.0
SHIRPA	hindlimb digit shape	0.0 %	1.00
SHIRPA	hindlimb digit size	0.0 %	1.00
SHIRPA	hindlimb nail length	0.0 %	1.0
SHIRPA	hindlimb nail number	0.0 %	1.0
SHIRPA	hindlimb nail position	0.0 %	1.0
SHIRPA	hindlimb nail shape	0.0 %	1.0
SHIRPA	hindlimbs footpads	0.0 %	1.0
SHIRPA	hindlimbs position	0.0 %	1.0
SHIRPA	hindlimbs shape	0.0 %	1.0
SHIRPA	hindlimbs size	0.0 %	1.0
SHIRPA	hindpaw position	0.0 %	1.0
SHIRPA	hindpaw shape	0.0 %	1.0
SHIRPA	hindpaw size	0.0 %	1.0
SHIRPA	limb grasp	6.0 %	0.299
SHIRPA	lower lip morphology	0.0 %	1.0
SHIRPA	lower teeth appearance	0.0 %	1.0
SHIRPA	mouth morphology	0.0 %	1.0
SHIRPA	salivation	0.0 %	1.0
SHIRPA	skin color back paws	0.0 %	1.0
SHIRPA	skin color ear	0.0 %	1.0
SHIRPA	skin color front paws	0.0 %	1.0
SHIRPA	skin color snout	0.0 %	1.0
SHIRPA	skin color tail	0.0 %	1.0
SHIRPA	skin color whole body	0.0 %	1.0
SHIRPA	skin texture back paw	0.0 %	1.0
SHIRPA	skin texture ear	0.0 %	1.0
SHIRPA	skin texture front paws	0.0 %	1.0
SHIRPA	skin texture snout	0.0 %	1.0
SHIRPA	skin texture tail	0.0 %	1.0
SHIRPA	skin texture whole body	0.0 %	1.00
SHIRPA	snout size	0.0 %	1.0
SHIRPA	startle response	0.0 %	1.0
SHIRPA	tail curvature	0.0 %	1.00
SHIRPA	tail elevation	1.0 %	1.0
SHIRPA	tail length	0.0 %	1.0
SHIRPA	tail morphology	0.0 %	1.00
SHIRPA	tail presence	0.0 %	1.0
SHIRPA	tail shape	0.0 %	1.0
SHIRPA	tail thickness	0.0 %	1.0
SHIRPA	teeth presence	0.0 %	1.0
SHIRPA	transfer arousal	1.0 %	1.0
SHIRPA	tremor	0.0 %	1.00
SHIRPA	trunk curl	0.0 %	1.00
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	0.0 %	1.0
SHIRPA	upper lip morphology	0.0 %	1.0
SHIRPA	upper teeth appearance	0.0 %	1.0
SHIRPA	vibrissae appearance	1.0 %	1.0
SHIRPA	vibrissae presence	2.0 %	1.0
SHIRPA	vocalization	2.0 %	1.0

GENOTYPE CORRELATION PLOT

Correlate Aatf^em1(IMPC)J/Mmjax -/+ with genotype:

This genotype correlation visualization can include both EAP and LAP measures.