MPD: JaxKOMP-EAP genotype: Ergic1<sup>em1(IMPC)J</sup>/Mmjax -/+

JaxKOMP-EAP effect sizes: Ergic1^em1(IMPC)J/Mmjax -/+ Gene Ergic1

MULTIPLE (NUMERIC) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

Procedure	JaxKOMP-EAP Trait	Trait Effect	Trait Effect SE	Trait Effect RankZ	Adjusted p-value	Unadjusted p-value
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 6 kHz pip	3.5227	6.0016	0.76214	0.858	0.569
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 12 kHz pip	9.3612	9.1842	1.5946	0.751	0.330
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 18 kHz pip	8.4091	5.9815	1.2453	0.547	0.187
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 24 kHz pip	1.4390	5.1258	0.10646	0.923	0.785
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 30 kHz pip	6.7046	5.5755	1.0345	0.640	0.254
body composition	body length	-0.0071463	0.034556	0.10112	0.934	0.838
body composition	body weight (at time of DXA)	-0.89416	0.54772	-0.56252	0.288	0.112
body composition	bone area, whole body scan, head excluded	-0.21718	0.11499	-0.70392	0.266	0.0683
body composition	bone mineral content of whole body scan, head excluded	-0.015519	0.010305	-0.70217	0.391	0.142
body composition	bone mineral content to body weight ratio	-0.00055535	0.00039919	-0.53982	0.427	0.174
body composition	bone mineral density of whole body scan, head excluded	-0.00045693	0.00065040	-0.47105	0.747	0.488
body composition	fat tissue mass of whole body scan, head excluded	0.49570	0.32549	0.75923	0.356	0.138
body composition	fat tissue mass to body weight ratio	0.022783	0.010652	0.99392	0.165	0.0402
body composition	lean tissue mass of whole body scan, head excluded	-0.80578	0.30315	-1.5884	0.123	0.0123
body composition	lean tissue mass to body weight ratio	-0.022946	0.010147	-1.2407	0.159	0.0307
body composition	percent fat, whole body scan, head excluded	2.2475	1.0227	1.0586	0.152	0.0353
body composition	ratio of soft-tissue attenuation coefficients	-0.0024966	0.0011365	-1.0573	0.151	0.0354
body composition	tissue area	-0.15144	0.13136	-0.33125	0.561	0.258
body composition	total tissue mass, whole body scan, head excluded	-0.13098	0.21969	-0.53508	0.756	0.555
clinical blood chemistry	alanine transaminase (plasma ALT)	-11.273	9.1343	-0.94246	0.603	0.230
clinical blood chemistry	albumin (plasma Alb)	0.83906	1.1759	1.2430	0.765	0.483
clinical blood chemistry	alkaline phosphatase (plasma ALP)	4.9769	4.7670	0.39013	0.562	0.308
clinical blood chemistry	aspartate transaminase (plasma AST)	-20.808	9.3864	-0.93987	0.253	0.0373
clinical blood chemistry	aspartate transaminase to alanine transaminase ratio (plasma AST:ALT)	-0.014311	0.34864	-0.019873	0.993	0.968
clinical blood chemistry	blood urea nitrogen (BUN)	-4.9040	3.8568	-1.6997	0.479	0.217
clinical blood chemistry	calcium (plasma Ca)	-0.41757	0.20978	-2.2421	0.210	0.0591
clinical blood chemistry	creatinine (plasma)	-0.098600	0.045250	-1.6887	0.182	0.0403
clinical blood chemistry	glucose (plasma GLU, no fast)	17.554	17.160	0.98004	0.522	0.317
clinical blood chemistry	HDL cholesterol (plasma HDL)	7.7208	3.2747	1.4382	0.181	0.0273
clinical blood chemistry	HDL cholesterol to total cholesterol ratio	0.044984	0.023606	1.9602	0.342	0.0693
clinical blood chemistry	phosphorus (plasma phosphate)	-0.31323	1.2202	-0.55856	0.908	0.800
clinical blood chemistry	total bilirubin (plasma TBIL)	-0.015785	0.015780	-1.1067	0.682	0.328
clinical blood chemistry	total cholesterol (plasma CHOL, no fast)	0.64616	7.1311	-0.12043	0.973	0.929
clinical blood chemistry	total protein (plasma TP)	-1.1728	1.2557	-1.0061	0.626	0.360
clinical blood chemistry	triglyceride (plasma TG, no fast)	-13.967	14.201	-0.54023	0.621	0.336
glucose tolerance test	amount glucose injected	1.8014	1.8226	0.86258	0.700	0.334
glucose tolerance test	plasma glucose, 0min	17.529	5.2942	1.4017	0.0261	0.00318
glucose tolerance test	plasma glucose, 15min	-16.022	15.493	-0.33275	0.642	0.312
glucose tolerance test	plasma glucose, 30min	-7.5651	19.571	-0.098999	0.880	0.703
glucose tolerance test	plasma glucose, 60min	11.400	14.377	0.58493	0.738	0.436
glucose tolerance test	plasma glucose, 120min	22.730	7.2802	1.3729	0.0887	0.00515
grip strength	body weight (at time of grip strength test)	-1.0006	0.52631	-0.69651	0.178	0.0663
grip strength	forelimb and hindlimb grip strength (mean of trials), average	-10.645	6.6789	-0.50583	0.289	0.121
grip strength	forelimb and hindlimb grip strength (mean of trials), average normalized to bw	-0.55914	0.28601	-0.63757	0.187	0.0594
grip strength	forelimb and hindlimb grip strength by trial, trial1	-11.341	10.005	-0.54585	0.566	0.266
grip strength	forelimb and hindlimb grip strength by trial, trial2	-3.8593	6.2595	-0.017428	0.768	0.542
grip strength	forelimb and hindlimb grip strength by trial, trial3	-17.632	7.6479	-0.91466	0.154	0.0280
grip strength	forelimb grip strength (mean of trials), average	-9.1722	3.8144	-0.83584	0.127	0.0224
grip strength	forelimb grip strength (mean of trials), average normalized to bw	-0.45120	0.17299	-0.90150	0.0965	0.0139
grip strength	forelimb grip strength by trial, trial1	-17.037	5.0660	-1.5673	0.0503	0.00201
grip strength	forelimb grip strength by trial, trial2	-6.8478	4.9812	-0.52740	0.500	0.179
grip strength	forelimb grip strength by trial, trial3	-6.2666	5.0834	-0.44244	0.545	0.227
heart weight	heart weight, normalized to body weight	0.037105	0.24541	-0.30959	0.940	0.881
heart weight	heart weight, weight	2.2013	3.2043	-0.088625	0.691	0.500
hematology	basophil differential (percent of total WBC)	-0.024600	0.061278	-0.35314	0.912	0.692
hematology	calculated hemoglobin (cHGB)	-0.22007	0.34258	-0.90894	0.766	0.527
hematology	eosinophil differential (percent of total WBC)	-0.15296	0.39162	-0.34810	0.903	0.700
hematology	hematocrit (HCT)	0.41774	1.0964	0.077984	0.856	0.707
hematology	hemoglobin concentration distribution width (HDW)	-0.10958	0.036364	-2.2871	0.0826	0.00619
hematology	large unstained cells (percent of total WBC)	-0.016667	0.13188	-0.082606	0.951	0.901
hematology	lymphocyte differential (percent of total WBC)	3.5123	6.3152	1.1484	0.771	0.584
hematology	mean corpuscular hemoglobin (CHr)	0.016667	0.079224	0.16598	0.920	0.835
hematology	mean platelet volume (MPV)	-0.12254	0.31378	-0.91091	0.845	0.700
hematology	mean RBC corpuscular hemoglobin (MCH)	0.090101	0.14672	0.32345	0.811	0.545
hematology	mean RBC corpuscular hemoglobin concentration (MCHC)	0.98246	0.42657	1.5585	0.242	0.0311
hematology	mean RBC corpuscular volume (MCV)	0.068572	0.55975	0.16060	0.958	0.904
hematology	measured hemoglobin (mHGB)	-0.14199	0.38278	-0.58648	0.864	0.714
hematology	monocyte differential (percent of total WBC)	0.15833	0.10233	0.72424	0.493	0.135
hematology	neutrophil differential (percent of total WBC)	-3.5620	6.4669	-1.3545	0.767	0.587
hematology	platelet count (PLT; units per volume x 10³)	-78.304	128.50	-0.95801	0.818	0.548
hematology	RBC corpuscular distribution width (RDW)	-0.20833	0.19681	-0.77845	0.565	0.301
hematology	RBC corpuscular hemoglobin concentration mean (CHCM)	0.30086	0.30852	0.73474	0.600	0.340
hematology	red blood cell count (RBC; per volume x 10⁶)	-0.084560	0.21052	-0.69003	0.851	0.692
hematology	reticulocyte count (Retic; units per volume x 10⁹)	-39.368	26.545	-1.4275	0.535	0.152
hematology	reticulocyte differential (percent of total RBC)	-0.087084	0.19694	-0.14643	0.867	0.662
hematology	white blood cell count (WBC; units per volume x 10³)	0.14347	0.88332	0.29393	0.930	0.872
holeboard	number of hole pokes by individual hole number, 20 min test, 1	-0.65455	0.91380	-0.59852	0.826	0.480
holeboard	number of hole pokes by individual hole number, 20 min test, 2	-0.69405	0.46604	-0.96071	0.678	0.148
holeboard	number of hole pokes by individual hole number, 20 min test, 3	0.10929	0.44433	0.27958	0.951	0.808
holeboard	number of hole pokes by individual hole number, 20 min test, 4	-1.8739	0.81912	-1.8030	0.368	0.0302
holeboard	number of hole pokes by individual hole number, 20 min test, 5	-1.1652	0.78040	-1.7383	0.650	0.147
holeboard	number of hole pokes by individual hole number, 20 min test, 6	-0.095160	0.36849	-0.25230	0.968	0.798
holeboard	number of hole pokes by individual hole number, 20 min test, 7	0.37118	0.33826	0.95446	0.835	0.283
holeboard	number of hole pokes by individual hole number, 20 min test, 8	-0.17589	0.43518	-0.17903	0.939	0.689
holeboard	number of hole pokes by individual hole number, 20 min test, 9	-0.67614	0.50357	-1.0857	0.666	0.191
holeboard	number of hole pokes by individual hole number, 20 min test, 10	0.64695	0.29284	1.5053	0.582	0.0362
holeboard	number of hole pokes by individual hole number, 20 min test, 11	-0.19479	0.44250	-0.51319	0.925	0.663
holeboard	number of hole pokes by individual hole number, 20 min test, 12	-0.22045	0.45241	-0.28905	0.917	0.630
holeboard	number of hole pokes by individual hole number, 20 min test, 13	-1.8750	0.73976	-1.7865	0.353	0.0174
holeboard	number of hole pokes by individual hole number, 20 min test, 14	-0.56269	0.49636	-0.79726	0.695	0.267
holeboard	number of hole pokes by individual hole number, 20 min test, 15	-0.030684	0.53662	0.052316	0.984	0.955
holeboard	number of hole pokes by individual hole number, 20 min test, 16	-1.6962	0.99972	-1.4561	0.528	0.102
holeboard	total number of hole pokes, 20 min test	-7.9205	4.7466	-1.0536	0.360	0.107
light / dark	latency to enter dark zone, 20 min test	115.99	61.326	1.7644	0.486	0.0725
light / dark	number of transitions between light and dark zones, 20 min test	-38.413	13.684	-2.6715	0.117	0.0103
light / dark	percentage of total time in dark zone, 20 min test	4.5461	5.4445	0.92304	0.724	0.413
light / dark	percentage of total time in light zone, 20 min test	-4.5461	5.4445	-0.93344	0.721	0.413
light / dark	time mobile in dark zone, 20 min test	-47.601	16.349	-2.3811	0.0801	0.00809
light / dark	time mobile in light zone, 20 min test	-33.810	17.823	-2.1966	0.262	0.0717
light / dark	time spent in dark zone, 20 min test	-45.101	75.140	-0.46963	0.855	0.555
light / dark	time spent in light zone, 20 min test	45.101	75.140	0.46963	0.855	0.555
open field	average speed in center of arena, 20 min test	-0.27875	0.41421	-0.59523	0.793	0.506
open field	average speed in periphery of arena, 20 min test	-0.31177	0.16554	-1.6415	0.201	0.0688
open field	distance traveled habituation ratio, 20 min test	3.8460	7.4038	0.35005	0.826	0.607
open field	distance traveled in center of arena, 20 min test	-199.94	122.95	-1.5778	0.325	0.114
open field	distance traveled in periphery of arena, 20 min test	-272.72	201.36	-1.5371	0.408	0.185
open field	distance traveled slope, 20 min test	1.0335	6.9277	0.17612	0.973	0.882
open field	distance traveled, 20 min test, 1st 5min	-149.52	80.518	-1.4907	0.240	0.0725
open field	distance traveled, 20 min test, 2nd 5min	-72.315	61.365	-1.3609	0.481	0.247
open field	distance traveled, 20 min test, 3rd 5min	-143.28	66.362	-1.8503	0.159	0.0385
open field	distance traveled, 20 min test, 4th 5min	-111.25	61.034	-1.6955	0.253	0.0777
open field	number of clockwise revolution episodes, 20 min test	-4.1064	1.3166	-2.5883	0.0624	0.00382
open field	number of counter-clockwise revolution episodes, 20 min test	-1.3198	1.2163	-1.1333	0.569	0.286
open field	number of rears in 5 min bins, 20 min test, 1st 5min	0.34570	1.6825	-0.11849	0.940	0.839
open field	number of rears in 5 min bins, 20 min test, 2nd 5min	-1.2145	2.7116	-0.65898	0.835	0.657
open field	number of rears in 5 min bins, 20 min test, 3rd 5min	-2.5916	2.7649	-0.90331	0.625	0.356
open field	number of rears in 5 min bins, 20 min test, 4th 5min	-3.2096	2.6725	-1.0320	0.512	0.239
open field	percentage of total time in center of arena, 20 min test	-0.69950	6.7330	-0.37011	0.977	0.918
open field	percentage of total time in center of arena, slope, 20 min test	-0.40950	1.5282	-0.10964	0.955	0.790
open field	percentage of total time in center, habituation ratio, 20 min test	-0.45813	1.4895	-0.13263	0.944	0.760
open field	percentage of total time in corners of arena, 20 min test	2.5166	5.6168	0.75198	0.854	0.657
open field	percentage of total time in corners, habituation ratio, 20 min test	-0.60261	2.1344	-0.56978	0.959	0.780
open field	percentage of total time in corners, slope, 20 min test	-0.90927	2.1999	-0.73429	0.931	0.682
open field	permanence time in center of arena, 20 min test	-8.4000	80.796	-0.37011	0.976	0.918
open field	permanence time in corners of arena, 20 min test	30.206	67.398	0.75376	0.855	0.657
open field	permanence time in periphery of arena, 20 min test	8.4100	80.797	0.37011	0.976	0.918
open field	total distance traveled, 20 min test	-478.80	236.52	-1.7487	0.171	0.0513
open field	total number of rears, 20 min test	-6.8006	8.5485	-0.81963	0.675	0.432
open field	whole arena average speed, 20 min test	-0.39921	0.19715	-1.7549	0.171	0.0513
open field	whole arena resting time, 20 min test	43.799	22.878	1.7938	0.195	0.0645
open field	whole arena time spent mobile, 20 min test	-43.764	22.877	-2.0575	0.195	0.0647
open field	whole arena time spent vertical, 20 min test	-8.3197	7.6055	-0.76811	0.594	0.282
SHIRPA	locomotor activity (number of squares in the arena the mouse moves into with all four paws in first 30 s of test)	3.3053	1.5766	1.4894	0.241	0.0443
startle / PPI	average baseline movement during background noise	1.7512	1.2240	1.0815	0.714	0.163
startle / PPI	average of each corrected maximum percent pre-pulse inhibition value	-0.024167	0.068446	-0.31551	0.887	0.726
startle / PPI	average of each corrected percent pre-pulse inhibition value	-0.043710	0.066528	-0.50216	0.802	0.516
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-0.92726	10.273	-0.052567	0.995	0.929
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-4.2450	6.7581	-0.46065	0.805	0.534
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-5.8479	6.8439	-0.65570	0.698	0.399
startle / PPI	average startle response to full pulse (120 dB)	-55.823	41.128	-0.78849	0.413	0.184
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-64.579	39.332	-0.96110	0.299	0.110
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-35.769	34.880	-0.52392	0.530	0.313
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-27.031	28.529	-0.46532	0.571	0.350
startle / PPI	average startle response to pre-pulse, 74dB sound pressure level	3.0145	2.2553	1.5755	0.721	0.191
startle / PPI	average startle response to pre-pulse, 78dB sound pressure level	-3.6229	1.7760	-2.0179	0.488	0.0497
startle / PPI	average startle response to pre-pulse, 82dB sound pressure level	-1.6250	2.3033	-1.0518	0.819	0.486
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	0.0097130	0.097985	0.12997	0.991	0.922
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-0.059128	0.075985	-0.56524	0.731	0.442
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-0.049383	0.077481	-0.56407	0.757	0.528
startle / PPI	corrected average startle response to full pulse (120 dB) minus average baseline movement during background noise	-56.485	40.816	-0.79616	0.399	0.176
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 74dB sound pressure level	-66.660	39.714	-0.98586	0.287	0.103
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 78dB sound pressure level	-32.043	35.461	-0.46220	0.581	0.373
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 82dB sound pressure level	-25.406	28.798	-0.40068	0.593	0.384
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	0.0020608	0.098209	0.056776	0.998	0.983
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-0.033245	0.078836	-0.34159	0.861	0.676
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-0.041316	0.080834	-0.48838	0.812	0.613
startle / PPI	corrected maximum startle response to full pulse (120 dB) minus maximum baseline movement during background noise	-160.55	156.41	-0.60949	0.558	0.313
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 74dB sound pressure level	-239.37	147.73	-0.98586	0.307	0.115
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 78dB sound pressure level	-135.25	136.38	-0.55962	0.547	0.329
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 82dB sound pressure level	-105.34	109.05	-0.45909	0.555	0.341
startle / PPI	maximum baseline movement during background noise	6.4650	3.6891	1.4809	0.556	0.0896
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-1.9788	10.430	-0.15261	0.985	0.851
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-1.5370	7.3052	-0.20387	0.939	0.835
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-4.5721	7.5462	-0.54981	0.791	0.549
startle / PPI	maximum startle response to full pulse (120 dB)	-153.99	157.40	-0.57773	0.576	0.335
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-232.75	147.06	-0.96110	0.320	0.123
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-143.56	135.30	-0.58936	0.516	0.297
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-109.56	108.70	-0.50314	0.541	0.321
startle / PPI	maximum startle response to pre-pulse, 74dB sound pressure level	8.7307	4.6570	1.8387	0.537	0.0703
startle / PPI	maximum startle response to pre-pulse, 78dB sound pressure level	-8.3167	4.7863	-2.0288	0.582	0.0919
startle / PPI	maximum startle response to pre-pulse, 82dB sound pressure level	-4.2271	5.3058	-1.0690	0.788	0.432

MULTIPLE (CATEGORICAL) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

Procedure	JaxKOMP-EAP Trait	Sex	Trait Effect	P-value
eye morphology	anterior chamber depth	females	1.0 %	1.0
eye morphology	anterior chamber depth	males	0.0 %	1.0
eye morphology	anterior chamber depth	both	1.0 %	1.0
eye morphology	bulging eye	females	1.0 %	1.0
eye morphology	bulging eye	males	0.0 %	1.0
eye morphology	bulging eye	both	1.0 %	1.00
eye morphology	cornea	females	4.0 %	1.0
eye morphology	cornea	males	2.0 %	1.0
eye morphology	cornea	both	3.0 %	1.00
eye morphology	cornea opacity	females	9.0 %	0.359
eye morphology	cornea opacity	males	1.0 %	1.0
eye morphology	cornea opacity	both	4.0 %	0.428
eye morphology	cornea vascularization	females	3.0 %	1.0
eye morphology	cornea vascularization	males	1.0 %	1.0
eye morphology	cornea vascularization	both	2.0 %	1.00
eye morphology	corneal deposits	females	2.0 %	1.0
eye morphology	corneal deposits	males	1.0 %	1.0
eye morphology	corneal deposits	both	1.0 %	1.00
eye morphology	corneal mineralization	females	2.0 %	1.0
eye morphology	corneal mineralization	males	1.0 %	1.0
eye morphology	corneal mineralization	both	1.0 %	1.00
eye morphology	corneal scleralization	females	3.0 %	1.00
eye morphology	corneal scleralization	males	1.0 %	1.0
eye morphology	corneal scleralization	both	2.0 %	1.00
eye morphology	corneal ulcer	females	1.0 %	1.0
eye morphology	corneal ulcer	males	1.0 %	1.0
eye morphology	corneal ulcer	both	1.0 %	1.00
eye morphology	eye closure	females	1.0 %	1.00
eye morphology	eye closure	males	0.0 %	1.0
eye morphology	eye closure	both	1.0 %	1.0
eye morphology	eye hemorrhage or blood presence	females	2.0 %	1.00
eye morphology	eye hemorrhage or blood presence	males	1.0 %	1.0
eye morphology	eye hemorrhage or blood presence	both	1.0 %	1.00
eye morphology	eyelid morphology	females	1.0 %	1.0
eye morphology	eyelid morphology	males	0.0 %	1.0
eye morphology	eyelid morphology	both	1.0 %	1.0
eye morphology	eyes (present, absent)	females	1.0 %	1.0
eye morphology	eyes (present, absent)	males	0.0 %	1.0
eye morphology	eyes (present, absent)	both	0.0 %	1.0
eye morphology	fusion between cornea and lens	females	4.0 %	1.00
eye morphology	fusion between cornea and lens	males	2.0 %	1.0
eye morphology	fusion between cornea and lens	both	3.0 %	1.00
eye morphology	iris pigmentation	females	2.0 %	1.0
eye morphology	iris pigmentation	males	1.0 %	1.0
eye morphology	iris pigmentation	both	2.0 %	1.00
eye morphology	iris transillumination	females	2.0 %	1.00
eye morphology	iris transillumination	males	1.0 %	1.0
eye morphology	iris transillumination	both	1.0 %	1.00
eye morphology	irispupil	females	4.0 %	1.00
eye morphology	irispupil	males	3.0 %	1.0
eye morphology	irispupil	both	3.0 %	1.00
eye morphology	lacrimation	females	3.0 %	1.0
eye morphology	lacrimation	males	2.0 %	1.0
eye morphology	lacrimation	both	3.0 %	1.0
eye morphology	lens	females	10.0 %	1.00
eye morphology	lens	males	8.0 %	1.0
eye morphology	lens	both	9.0 %	1.0
eye morphology	lens opacity	females	9.0 %	0.531
eye morphology	lens opacity	males	6.0 %	1.0
eye morphology	lens opacity	both	3.0 %	0.703
eye morphology	narrow eye opening	females	2.0 %	1.0
eye morphology	narrow eye opening	males	1.0 %	1.0
eye morphology	narrow eye opening	both	1.0 %	1.0
eye morphology	optic disc	females	4.0 %	1.00
eye morphology	optic disc	males	2.0 %	1.0
eye morphology	optic disc	both	3.0 %	1.00
eye morphology	persistence of hyaloid vascular system	females	24.0 %	0.155
eye morphology	persistence of hyaloid vascular system	males	5.0 %	1.0
eye morphology	persistence of hyaloid vascular system	both	9.0 %	0.261
eye morphology	pupil dilation	females	2.0 %	1.0
eye morphology	pupil dilation	males	1.0 %	1.0
eye morphology	pupil dilation	both	2.0 %	1.0
eye morphology	pupil light response	females	2.0 %	1.00
eye morphology	pupil light response	males	1.0 %	1.0
eye morphology	pupil light response	both	2.0 %	1.00
eye morphology	pupil position	females	4.0 %	1.00
eye morphology	pupil position	males	3.0 %	1.0
eye morphology	pupil position	both	4.0 %	1.00
eye morphology	pupil shape	females	3.0 %	1.00
eye morphology	pupil shape	males	2.0 %	1.0
eye morphology	pupil shape	both	3.0 %	1.00
eye morphology	retina	females	10.0 %	1.0
eye morphology	retina	males	16.0 %	1.0
eye morphology	retina	both	13.0 %	1.0
eye morphology	retinal blood vessels	females	4.0 %	1.0
eye morphology	retinal blood vessels	males	2.0 %	1.0
eye morphology	retinal blood vessels	both	3.0 %	1.0
eye morphology	retinal blood vessels pattern	females	5.0 %	1.0
eye morphology	retinal blood vessels pattern	males	2.0 %	1.0
eye morphology	retinal blood vessels pattern	both	4.0 %	1.00
eye morphology	retinal blood vessels structure	females	4.0 %	1.00
eye morphology	retinal blood vessels structure	males	2.0 %	1.0
eye morphology	retinal blood vessels structure	both	3.0 %	1.00
eye morphology	retinal pigmentation	females	12.0 %	1.0
eye morphology	retinal pigmentation	males	14.0 %	1.0
eye morphology	retinal pigmentation	both	13.0 %	1.0
eye morphology	retinal structure	females	4.0 %	1.00
eye morphology	retinal structure	males	2.0 %	1.0
eye morphology	retinal structure	both	3.0 %	1.00
eye morphology	synechia	females	4.0 %	1.0
eye morphology	synechia	males	2.0 %	1.0
eye morphology	synechia	both	3.0 %	1.00
eye morphology	vitreous	females	4.0 %	1.00
eye morphology	vitreous	males	2.0 %	1.0
eye morphology	vitreous	both	3.0 %	1.00
SHIRPA	activity body position	females	12.0 %	0.0797
SHIRPA	activity body position	males	12.0 %	0.126
SHIRPA	activity body position	both	12.0 %	0.0114
SHIRPA	aggression	females	0.0 %	1.00
SHIRPA	aggression	males	12.0 %	0.0522
SHIRPA	aggression	both	6.0 %	0.0878
SHIRPA	body length	females	0.0 %	1.0
SHIRPA	body length	males	0.0 %	1.00
SHIRPA	body length	both	0.0 %	1.00
SHIRPA	body position	females	0.0 %	1.0
SHIRPA	body position	males	1.0 %	1.0
SHIRPA	body position	both	0.0 %	1.0
SHIRPA	body thickness	females	1.0 %	1.0
SHIRPA	body thickness	males	0.0 %	1.0
SHIRPA	body thickness	both	0.0 %	1.0
SHIRPA	coat color abdomen	females	3.0 %	1.00
SHIRPA	coat color abdomen	males	4.0 %	1.0
SHIRPA	coat color abdomen	both	4.0 %	1.0
SHIRPA	coat color back	females	0.0 %	1.0
SHIRPA	coat color back	males	0.0 %	1.00
SHIRPA	coat color back	both	0.0 %	1.00
SHIRPA	coat color head	females	0.0 %	1.0
SHIRPA	coat color head	males	0.0 %	1.00
SHIRPA	coat color head	both	0.0 %	1.0
SHIRPA	coat color pattern abdomen	females	1.0 %	1.0
SHIRPA	coat color pattern abdomen	males	1.0 %	1.0
SHIRPA	coat color pattern abdomen	both	1.0 %	1.0
SHIRPA	coat color pattern back	females	0.0 %	1.0
SHIRPA	coat color pattern back	males	0.0 %	1.00
SHIRPA	coat color pattern back	both	0.0 %	1.0
SHIRPA	coat color pattern head	females	0.0 %	1.0
SHIRPA	coat color pattern head	males	0.0 %	1.0
SHIRPA	coat color pattern head	both	0.0 %	1.00
SHIRPA	coat hair abdomen texture appearance	females	2.0 %	1.0
SHIRPA	coat hair abdomen texture appearance	males	2.0 %	1.0
SHIRPA	coat hair abdomen texture appearance	both	2.0 %	1.0
SHIRPA	coat hair back texture appearance	females	0.0 %	1.0
SHIRPA	coat hair back texture appearance	males	0.0 %	1.0
SHIRPA	coat hair back texture appearance	both	0.0 %	1.0
SHIRPA	coat hair distribution abdomen	females	0.0 %	1.0
SHIRPA	coat hair distribution abdomen	males	24.0 %	0.00365
SHIRPA	coat hair distribution abdomen	both	12.0 %	0.00512
SHIRPA	coat hair distribution back	females	0.0 %	1.0
SHIRPA	coat hair distribution back	males	0.0 %	1.0
SHIRPA	coat hair distribution back	both	0.0 %	1.0
SHIRPA	coat hair distribution head	females	1.0 %	1.00
SHIRPA	coat hair distribution head	males	1.0 %	1.0
SHIRPA	coat hair distribution head	both	1.0 %	1.0
SHIRPA	coat hair head texture appearance	females	0.0 %	1.00
SHIRPA	coat hair head texture appearance	males	0.0 %	1.0
SHIRPA	coat hair head texture appearance	both	0.0 %	1.0
SHIRPA	contact righting	females	5.0 %	1.0
SHIRPA	contact righting	males	5.0 %	1.00
SHIRPA	contact righting	both	5.0 %	1.00
SHIRPA	ear morphology	females	0.0 %	1.0
SHIRPA	ear morphology	males	0.0 %	1.0
SHIRPA	ear morphology	both	0.0 %	1.0
SHIRPA	fat distribution	females	0.0 %	1.0
SHIRPA	fat distribution	males	0.0 %	1.0
SHIRPA	fat distribution	both	0.0 %	1.00
SHIRPA	forelimb digit number	females	0.0 %	1.00
SHIRPA	forelimb digit number	males	0.0 %	1.0
SHIRPA	forelimb digit number	both	0.0 %	1.00
SHIRPA	forelimb digit position	females	0.0 %	1.0
SHIRPA	forelimb digit position	males	0.0 %	1.0
SHIRPA	forelimb digit position	both	0.0 %	1.0
SHIRPA	forelimb digit shape	females	0.0 %	1.0
SHIRPA	forelimb digit shape	males	0.0 %	1.0
SHIRPA	forelimb digit shape	both	0.0 %	1.0
SHIRPA	forelimb digit size	females	0.0 %	1.0
SHIRPA	forelimb digit size	males	0.0 %	1.0
SHIRPA	forelimb digit size	both	0.0 %	1.0
SHIRPA	forelimb footpads	females	0.0 %	1.0
SHIRPA	forelimb footpads	males	0.0 %	1.0
SHIRPA	forelimb footpads	both	0.0 %	1.0
SHIRPA	forelimb nail length	females	0.0 %	1.0
SHIRPA	forelimb nail length	males	0.0 %	1.0
SHIRPA	forelimb nail length	both	0.0 %	1.0
SHIRPA	forelimb nail number	females	0.0 %	1.0
SHIRPA	forelimb nail number	males	0.0 %	1.0
SHIRPA	forelimb nail number	both	0.0 %	1.0
SHIRPA	forelimb nail position	females	0.0 %	1.0
SHIRPA	forelimb nail position	males	0.0 %	1.0
SHIRPA	forelimb nail position	both	0.0 %	1.0
SHIRPA	forelimb nail shape	females	0.0 %	1.0
SHIRPA	forelimb nail shape	males	0.0 %	1.0
SHIRPA	forelimb nail shape	both	0.0 %	1.0
SHIRPA	forelimbs position	females	0.0 %	1.0
SHIRPA	forelimbs position	males	0.0 %	1.0
SHIRPA	forelimbs position	both	0.0 %	1.0
SHIRPA	forelimbs shape	females	0.0 %	1.0
SHIRPA	forelimbs shape	males	0.0 %	1.0
SHIRPA	forelimbs shape	both	0.0 %	1.0
SHIRPA	forelimbs size	females	0.0 %	1.0
SHIRPA	forelimbs size	males	0.0 %	1.0
SHIRPA	forelimbs size	both	0.0 %	1.0
SHIRPA	forepaw position	females	0.0 %	1.0
SHIRPA	forepaw position	males	0.0 %	1.0
SHIRPA	forepaw position	both	0.0 %	1.0
SHIRPA	forepaw shape	females	0.0 %	1.0
SHIRPA	forepaw shape	males	0.0 %	1.0
SHIRPA	forepaw shape	both	0.0 %	1.0
SHIRPA	forepaw size	females	0.0 %	1.0
SHIRPA	forepaw size	males	0.0 %	1.0
SHIRPA	forepaw size	both	0.0 %	1.0
SHIRPA	gait (fluidity)	females	0.0 %	1.0
SHIRPA	gait (fluidity)	males	0.0 %	1.00
SHIRPA	gait (fluidity)	both	0.0 %	1.00
SHIRPA	genitalia morphology	females	0.0 %	1.00
SHIRPA	genitalia morphology	males	0.0 %	1.0
SHIRPA	genitalia morphology	both	0.0 %	1.00
SHIRPA	genitalia presence	females	0.0 %	1.0
SHIRPA	genitalia presence	males	0.0 %	1.0
SHIRPA	genitalia presence	both	0.0 %	1.0
SHIRPA	genitalia size	females	0.0 %	1.0
SHIRPA	genitalia size	males	0.0 %	1.0
SHIRPA	genitalia size	both	0.0 %	1.0
SHIRPA	head bobbing	females	0.0 %	1.0
SHIRPA	head bobbing	males	0.0 %	1.0
SHIRPA	head bobbing	both	0.0 %	1.0
SHIRPA	head morphology	females	0.0 %	1.0
SHIRPA	head morphology	males	0.0 %	1.00
SHIRPA	head morphology	both	0.0 %	1.0
SHIRPA	head size	females	0.0 %	1.0
SHIRPA	head size	males	0.0 %	1.0
SHIRPA	head size	both	0.0 %	1.00
SHIRPA	hindlimb digit number	females	1.0 %	1.00
SHIRPA	hindlimb digit number	males	0.0 %	1.0
SHIRPA	hindlimb digit number	both	0.0 %	1.00
SHIRPA	hindlimb digit position	females	0.0 %	1.0
SHIRPA	hindlimb digit position	males	0.0 %	1.0
SHIRPA	hindlimb digit position	both	0.0 %	1.0
SHIRPA	hindlimb digit shape	females	0.0 %	1.0
SHIRPA	hindlimb digit shape	males	0.0 %	1.0
SHIRPA	hindlimb digit shape	both	0.0 %	1.0
SHIRPA	hindlimb digit size	females	0.0 %	1.00
SHIRPA	hindlimb digit size	males	0.0 %	1.0
SHIRPA	hindlimb digit size	both	0.0 %	1.00
SHIRPA	hindlimb nail length	females	0.0 %	1.0
SHIRPA	hindlimb nail length	males	0.0 %	1.0
SHIRPA	hindlimb nail length	both	0.0 %	1.00
SHIRPA	hindlimb nail number	females	0.0 %	1.0
SHIRPA	hindlimb nail number	males	1.0 %	1.0
SHIRPA	hindlimb nail number	both	0.0 %	1.00
SHIRPA	hindlimb nail position	females	0.0 %	1.0
SHIRPA	hindlimb nail position	males	0.0 %	1.0
SHIRPA	hindlimb nail position	both	0.0 %	1.0
SHIRPA	hindlimb nail shape	females	0.0 %	1.0
SHIRPA	hindlimb nail shape	males	0.0 %	1.0
SHIRPA	hindlimb nail shape	both	0.0 %	1.0
SHIRPA	hindlimbs footpads	females	0.0 %	1.0
SHIRPA	hindlimbs footpads	males	0.0 %	1.0
SHIRPA	hindlimbs footpads	both	0.0 %	1.0
SHIRPA	hindlimbs position	females	0.0 %	1.0
SHIRPA	hindlimbs position	males	0.0 %	1.0
SHIRPA	hindlimbs position	both	0.0 %	1.0
SHIRPA	hindlimbs shape	females	0.0 %	1.0
SHIRPA	hindlimbs shape	males	0.0 %	1.0
SHIRPA	hindlimbs shape	both	0.0 %	1.0
SHIRPA	hindlimbs size	females	0.0 %	1.0
SHIRPA	hindlimbs size	males	0.0 %	1.0
SHIRPA	hindlimbs size	both	0.0 %	1.0
SHIRPA	hindpaw position	females	0.0 %	1.0
SHIRPA	hindpaw position	males	0.0 %	1.0
SHIRPA	hindpaw position	both	0.0 %	1.0
SHIRPA	hindpaw shape	females	0.0 %	1.0
SHIRPA	hindpaw shape	males	0.0 %	1.0
SHIRPA	hindpaw shape	both	0.0 %	1.0
SHIRPA	hindpaw size	females	0.0 %	1.0
SHIRPA	hindpaw size	males	0.0 %	1.0
SHIRPA	hindpaw size	both	0.0 %	1.0
SHIRPA	limb grasp	females	4.0 %	0.524
SHIRPA	limb grasp	males	6.0 %	1.0
SHIRPA	limb grasp	both	1.0 %	1.0
SHIRPA	lower lip morphology	females	0.0 %	1.0
SHIRPA	lower lip morphology	males	0.0 %	1.0
SHIRPA	lower lip morphology	both	0.0 %	1.0
SHIRPA	lower teeth appearance	females	0.0 %	1.0
SHIRPA	lower teeth appearance	males	0.0 %	1.00
SHIRPA	lower teeth appearance	both	0.0 %	1.00
SHIRPA	mouth morphology	females	0.0 %	1.0
SHIRPA	mouth morphology	males	0.0 %	1.00
SHIRPA	mouth morphology	both	0.0 %	1.00
SHIRPA	salivation	females	0.0 %	1.0
SHIRPA	salivation	males	0.0 %	1.0
SHIRPA	salivation	both	0.0 %	1.0
SHIRPA	skin color back paws	females	0.0 %	1.0
SHIRPA	skin color back paws	males	0.0 %	1.0
SHIRPA	skin color back paws	both	0.0 %	1.0
SHIRPA	skin color ear	females	0.0 %	1.0
SHIRPA	skin color ear	males	0.0 %	1.0
SHIRPA	skin color ear	both	0.0 %	1.0
SHIRPA	skin color front paws	females	0.0 %	1.0
SHIRPA	skin color front paws	males	0.0 %	1.0
SHIRPA	skin color front paws	both	0.0 %	1.0
SHIRPA	skin color snout	females	0.0 %	1.0
SHIRPA	skin color snout	males	0.0 %	1.0
SHIRPA	skin color snout	both	0.0 %	1.0
SHIRPA	skin color tail	females	0.0 %	1.0
SHIRPA	skin color tail	males	0.0 %	1.0
SHIRPA	skin color tail	both	0.0 %	1.0
SHIRPA	skin color whole body	females	0.0 %	1.0
SHIRPA	skin color whole body	males	0.0 %	1.0
SHIRPA	skin color whole body	both	0.0 %	1.0
SHIRPA	skin texture back paw	females	0.0 %	1.0
SHIRPA	skin texture back paw	males	0.0 %	1.0
SHIRPA	skin texture back paw	both	0.0 %	1.0
SHIRPA	skin texture ear	females	0.0 %	1.0
SHIRPA	skin texture ear	males	0.0 %	1.0
SHIRPA	skin texture ear	both	0.0 %	1.0
SHIRPA	skin texture front paws	females	0.0 %	1.0
SHIRPA	skin texture front paws	males	0.0 %	1.0
SHIRPA	skin texture front paws	both	0.0 %	1.0
SHIRPA	skin texture snout	females	0.0 %	1.0
SHIRPA	skin texture snout	males	0.0 %	1.0
SHIRPA	skin texture snout	both	0.0 %	1.0
SHIRPA	skin texture tail	females	0.0 %	1.0
SHIRPA	skin texture tail	males	0.0 %	1.0
SHIRPA	skin texture tail	both	0.0 %	1.0
SHIRPA	skin texture whole body	females	0.0 %	1.0
SHIRPA	skin texture whole body	males	0.0 %	1.00
SHIRPA	skin texture whole body	both	0.0 %	1.00
SHIRPA	snout size	females	0.0 %	1.0
SHIRPA	snout size	males	1.0 %	1.0
SHIRPA	snout size	both	0.0 %	1.0
SHIRPA	startle response	females	0.0 %	1.00
SHIRPA	startle response	males	0.0 %	1.00
SHIRPA	startle response	both	0.0 %	1.00
SHIRPA	tail curvature	females	0.0 %	1.00
SHIRPA	tail curvature	males	0.0 %	1.0
SHIRPA	tail curvature	both	0.0 %	1.0
SHIRPA	tail elevation	females	1.0 %	1.00
SHIRPA	tail elevation	males	2.0 %	1.0
SHIRPA	tail elevation	both	1.0 %	1.0
SHIRPA	tail length	females	0.0 %	1.0
SHIRPA	tail length	males	0.0 %	1.0
SHIRPA	tail length	both	0.0 %	1.00
SHIRPA	tail morphology	females	0.0 %	1.00
SHIRPA	tail morphology	males	0.0 %	1.0
SHIRPA	tail morphology	both	0.0 %	1.00
SHIRPA	tail presence	females	0.0 %	1.0
SHIRPA	tail presence	males	0.0 %	1.0
SHIRPA	tail presence	both	0.0 %	1.0
SHIRPA	tail shape	females	0.0 %	1.0
SHIRPA	tail shape	males	0.0 %	1.0
SHIRPA	tail shape	both	0.0 %	1.00
SHIRPA	tail thickness	females	0.0 %	1.0
SHIRPA	tail thickness	males	0.0 %	1.0
SHIRPA	tail thickness	both	0.0 %	1.0
SHIRPA	teeth presence	females	0.0 %	1.0
SHIRPA	teeth presence	males	0.0 %	1.00
SHIRPA	teeth presence	both	0.0 %	1.00
SHIRPA	transfer arousal	females	24.0 %	0.00178
SHIRPA	transfer arousal	males	12.0 %	0.128
SHIRPA	transfer arousal	both	18.0 %	0.000390
SHIRPA	tremor	females	0.0 %	1.0
SHIRPA	tremor	males	0.0 %	1.0
SHIRPA	tremor	both	0.0 %	1.00
SHIRPA	trunk curl	females	0.0 %	1.00
SHIRPA	trunk curl	males	0.0 %	1.0
SHIRPA	trunk curl	both	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	females	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	males	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	both	0.0 %	1.00
SHIRPA	upper lip morphology	females	0.0 %	1.0
SHIRPA	upper lip morphology	males	0.0 %	1.0
SHIRPA	upper lip morphology	both	0.0 %	1.0
SHIRPA	upper teeth appearance	females	0.0 %	1.0
SHIRPA	upper teeth appearance	males	0.0 %	1.0
SHIRPA	upper teeth appearance	both	0.0 %	1.00
SHIRPA	vibrissae appearance	females	2.0 %	1.0
SHIRPA	vibrissae appearance	males	1.0 %	1.0
SHIRPA	vibrissae appearance	both	1.0 %	1.0
SHIRPA	vibrissae presence	females	2.0 %	1.00
SHIRPA	vibrissae presence	males	1.0 %	1.0
SHIRPA	vibrissae presence	both	2.0 %	1.0
SHIRPA	vocalization	females	2.0 %	1.00
SHIRPA	vocalization	males	2.0 %	1.00
SHIRPA	vocalization	both	2.0 %	1.0

GENOTYPE CORRELATION PLOT

Correlate Ergic1^em1(IMPC)J/Mmjax -/+ with genotype: