MPD: JaxKOMP-EAP genotype: Slc25a48<sup>em1(IMPC)J</sup>/Mmjax -/-

JaxKOMP-EAP effect sizes: Slc25a48^em1(IMPC)J/Mmjax -/- Gene Slc25a48

MULTIPLE (NUMERIC) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

Procedure	JaxKOMP-EAP Trait	Trait Effect	Trait Effect SE	Trait Effect RankZ	Adjusted p-value	Unadjusted p-value
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 6 kHz pip	-10.441	13.229	-2.3136	0.824	0.488
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 12 kHz pip	-18.565	11.726	-2.6104	0.697	0.212
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 18 kHz pip	-12.345	17.698	-2.1927	0.820	0.536
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 24 kHz pip	-16.577	16.733	-2.2460	0.741	0.395
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 30 kHz pip	-4.7214	14.322	-0.73929	0.902	0.763
body composition	body length	0.0011240	0.050136	0.22931	0.994	0.982
body composition	body weight (at time of DXA)	-3.0314	1.3517	-1.6601	0.137	0.0364
body composition	bone area, whole body scan, head excluded	-0.29866	0.11561	-0.96307	0.116	0.0182
body composition	bone mineral content of whole body scan, head excluded	-0.022416	0.019984	-1.0350	0.565	0.276
body composition	bone mineral content to body weight ratio	-0.0011802	0.00072043	-1.2351	0.341	0.118
body composition	bone mineral density of whole body scan, head excluded	-0.00078278	0.0015530	-0.82423	0.814	0.620
body composition	fat tissue mass of whole body scan, head excluded	1.2282	0.82301	1.6180	0.377	0.152
body composition	fat tissue mass to body weight ratio	0.048139	0.028977	1.8281	0.302	0.113
body composition	lean tissue mass of whole body scan, head excluded	-0.89025	0.80376	-1.7226	0.582	0.282
body composition	lean tissue mass to body weight ratio	-0.055208	0.026427	-2.2079	0.207	0.0504
body composition	percent fat, whole body scan, head excluded	4.7978	2.7386	1.9060	0.280	0.0959
body composition	ratio of soft-tissue attenuation coefficients	-0.0051882	0.0030097	-1.9222	0.288	0.101
body composition	tissue area	0.13762	0.42432	0.63972	0.911	0.749
body composition	total tissue mass, whole body scan, head excluded	-0.11420	0.25385	-0.49455	0.823	0.658
clinical blood chemistry	alanine transaminase (plasma ALT)	-15.812	11.379	-1.2163	0.545	0.175
clinical blood chemistry	albumin (plasma Alb)	0.029596	0.47259	0.11145	0.989	0.950
clinical blood chemistry	alkaline phosphatase (plasma ALP)	4.3705	3.1310	0.26889	0.413	0.173
clinical blood chemistry	aspartate transaminase (plasma AST)	1.3333	9.7717	0.072370	0.976	0.892
clinical blood chemistry	aspartate transaminase to alanine transaminase ratio (plasma AST:ALT)	0.77372	0.25258	1.8253	0.121	0.00459
clinical blood chemistry	blood urea nitrogen (BUN)	-4.2538	1.3606	-1.5172	0.0495	0.00391
clinical blood chemistry	calcium (plasma Ca)	-0.17565	0.070956	-0.91610	0.105	0.0192
clinical blood chemistry	creatinine (plasma)	-0.019373	0.017142	-0.34915	0.521	0.267
clinical blood chemistry	glucose (plasma GLU, no fast)	-6.4399	12.212	0.052156	0.768	0.602
clinical blood chemistry	HDL cholesterol (plasma HDL)	1.2152	2.4354	-0.021965	0.844	0.621
clinical blood chemistry	HDL cholesterol to total cholesterol ratio	0.014350	0.0061634	0.65717	0.207	0.0271
clinical blood chemistry	phosphorus (plasma phosphate)	-0.23750	0.38229	-0.43908	0.774	0.539
clinical blood chemistry	total bilirubin (plasma TBIL)	0.0096876	0.0045064	0.60908	0.227	0.0398
clinical blood chemistry	total cholesterol (plasma CHOL, no fast)	-0.90750	3.3615	-0.40076	0.919	0.789
clinical blood chemistry	total protein (plasma TP)	0.36074	0.56033	0.19246	0.745	0.525
clinical blood chemistry	triglyceride (plasma TG, no fast)	-23.792	26.886	-1.0359	0.661	0.383
ERG v2.0	left eye a-wave amplitude (Photopic)	-1.5619	1.5838	-0.43073	0.676	0.340
ERG v2.0	left eye a-wave amplitude (Scotopic)	-8.5143	14.448	-0.43476	0.837	0.564
ERG v2.0	left eye a-wave implicit timing (Photopic)	1.4991	1.6724	0.94854	0.809	0.384
ERG v2.0	left eye a-wave implicit timing (Scotopic)	1.1749	0.67047	1.0215	0.537	0.102
ERG v2.0	left eye b-wave amplitude (Photopic)	2.9336	4.8570	0.049493	0.888	0.555
ERG v2.0	left eye b-wave amplitude (Scotopic)	37.043	38.124	0.66587	0.706	0.347
ERG v2.0	left eye b-wave implicit timing (Photopic)	-2.7662	3.4010	-0.46109	0.717	0.429
ERG v2.0	left eye b-wave implicit timing (Scotopic)	12.812	8.3376	1.2753	0.634	0.147
ERG v2.0	left eye c-wave amplitude (Scotopic)	20.274	36.124	0.58728	0.821	0.583
ERG v2.0	left eye c-wave implicit timing (Scotopic)	-117.68	78.347	-1.1398	0.577	0.154
ERG v2.0	left eye FO-like wave amplitude (Scotopic)	-40.369	46.274	-0.68141	0.711	0.397
ERG v2.0	left eye FO-like wave implicit timing (Scotopic)	-404.97	182.68	-1.2271	0.411	0.0425
ERG v2.0	right eye a-wave amplitude (Photopic)	0.35699	2.0633	0.22168	0.979	0.865
ERG v2.0	right eye a-wave amplitude (Scotopic)	12.235	18.017	0.16009	0.851	0.508
ERG v2.0	right eye a-wave implicit timing (Photopic)	-0.84760	1.0730	-0.43476	0.886	0.442
ERG v2.0	right eye a-wave implicit timing (Scotopic)	-0.54366	0.86331	-0.46327	0.838	0.538
ERG v2.0	right eye b-wave amplitude (Photopic)	-1.0679	6.9505	-0.28985	0.966	0.880
ERG v2.0	right eye b-wave amplitude (Scotopic)	-33.940	46.702	-0.39481	0.933	0.479
ERG v2.0	right eye b-wave implicit timing (Photopic)	-1.3690	2.6633	-0.16009	0.835	0.615
ERG v2.0	right eye b-wave implicit timing (Scotopic)	12.201	5.1576	1.2891	0.354	0.0319
ERG v2.0	right eye c-wave amplitude (Scotopic)	-80.433	29.587	-1.4122	0.258	0.0166
ERG v2.0	right eye c-wave implicit timing (Scotopic)	-72.768	54.513	-0.67276	0.751	0.202
ERG v2.0	right eye FO-like wave amplitude (Scotopic)	50.950	35.377	0.53579	0.554	0.170
ERG v2.0	right eye FO-like wave implicit timing (Scotopic)	265.07	278.70	1.0402	0.815	0.358
glucose tolerance test	amount glucose injected	-3.0022	1.7833	-0.49916	0.437	0.105
glucose tolerance test	plasma glucose, 0min	-21.646	6.6259	-1.9475	0.0263	0.00327
glucose tolerance test	plasma glucose, 15min	-43.877	31.070	-1.0844	0.479	0.170
glucose tolerance test	plasma glucose, 30min	6.6293	22.946	0.33130	0.911	0.775
glucose tolerance test	plasma glucose, 60min	-5.5629	18.859	-0.12386	0.913	0.771
glucose tolerance test	plasma glucose, 120min	11.030	10.917	0.63452	0.618	0.322
grip strength	body weight (at time of grip strength test)	-0.47354	0.64946	-0.23720	0.656	0.472
grip strength	forelimb and hindlimb grip strength (mean of trials), average	-5.8851	8.1189	-0.19289	0.674	0.474
grip strength	forelimb and hindlimb grip strength (mean of trials), average normalized to bw	-0.36132	0.37418	-0.30682	0.553	0.342
grip strength	forelimb and hindlimb grip strength by trial, trial1	1.0713	8.9210	0.29466	0.961	0.905
grip strength	forelimb and hindlimb grip strength by trial, trial2	-16.447	10.421	-0.80133	0.343	0.125
grip strength	forelimb and hindlimb grip strength by trial, trial3	1.0170	7.4136	0.27953	0.954	0.892
grip strength	forelimb grip strength (mean of trials), average	-10.169	5.3793	-0.95055	0.254	0.0687
grip strength	forelimb grip strength (mean of trials), average normalized to bw	-0.48862	0.25423	-0.99484	0.247	0.0645
grip strength	forelimb grip strength by trial, trial1	-3.3244	7.7450	-0.12376	0.865	0.671
grip strength	forelimb grip strength by trial, trial2	1.3229	7.0600	0.34665	0.943	0.853
grip strength	forelimb grip strength by trial, trial3	-21.322	6.4643	-1.8622	0.0556	0.00251
heart weight	heart weight, normalized to body weight	0.071895	0.10643	-0.19101	0.694	0.503
heart weight	heart weight, weight	0.15289	3.0243	-0.35961	0.974	0.960
hematology	basophil differential (percent of total WBC)	0.026263	0.023809	0.43324	0.706	0.279
hematology	eosinophil differential (percent of total WBC)	-0.32510	0.20632	-0.79124	0.515	0.126
hematology	hematocrit (HCT)	0.23680	0.47236	-0.12194	0.802	0.620
hematology	lymphocyte differential (percent of total WBC)	-1.9692	2.5778	-0.88487	0.675	0.451
hematology	mean corpuscular hemoglobin (CHr)	-0.060084	0.068532	-0.47103	0.629	0.388
hematology	mean platelet volume (MPV)	0.0026694	0.036385	-0.17862	0.975	0.942
hematology	mean RBC corpuscular hemoglobin concentration (MCHC)	0.091016	0.12390	0.22937	0.779	0.468
hematology	mean RBC corpuscular volume (MCV)	-0.39427	0.20958	-0.72246	0.210	0.0697
hematology	measured hemoglobin (mHGB)	0.12334	0.15347	0.065002	0.690	0.428
hematology	monocyte differential (percent of total WBC)	-0.24792	0.35285	-0.59997	0.778	0.488
hematology	neutrophil differential (percent of total WBC)	2.5358	2.3398	1.1917	0.535	0.287
hematology	platelet count (PLT; units per volume x 10³)	-3.7881	46.371	0.0027335	0.976	0.935
hematology	RBC corpuscular distribution width (RDW)	0.30232	0.13849	1.0279	0.186	0.0373
hematology	red blood cell count (RBC; per volume x 10⁶)	0.076641	0.11562	-0.012315	0.738	0.512
hematology	reticulocyte count (Retic; units per volume x 10⁹)	15.399	13.823	0.72404	0.661	0.274
hematology	reticulocyte differential (percent of total RBC)	0.11525	0.13283	0.69864	0.724	0.392
hematology	white blood cell count (WBC; units per volume x 10³)	-2.2704	0.84807	-1.3211	0.0633	0.0119
holeboard	number of hole pokes by individual hole number, 20 min test, 1	0.62574	0.86791	0.66867	0.825	0.475
holeboard	number of hole pokes by individual hole number, 20 min test, 2	-0.22388	0.54304	-0.21690	0.931	0.682
holeboard	number of hole pokes by individual hole number, 20 min test, 3	0.51356	0.64798	0.87579	0.853	0.433
holeboard	number of hole pokes by individual hole number, 20 min test, 4	-0.35211	0.91993	-0.25683	0.914	0.704
holeboard	number of hole pokes by individual hole number, 20 min test, 5	-0.099018	0.62173	-0.046436	0.970	0.874
holeboard	number of hole pokes by individual hole number, 20 min test, 6	-0.49564	0.59211	-1.3911	0.884	0.408
holeboard	number of hole pokes by individual hole number, 20 min test, 7	-0.016014	0.39133	-0.071897	1.00	0.968
holeboard	number of hole pokes by individual hole number, 20 min test, 8	-1.0392	0.62162	-1.5902	0.628	0.103
holeboard	number of hole pokes by individual hole number, 20 min test, 9	0.20651	0.52002	0.46559	0.939	0.694
holeboard	number of hole pokes by individual hole number, 20 min test, 10	-0.26615	0.50535	-0.65865	0.935	0.601
holeboard	number of hole pokes by individual hole number, 20 min test, 11	-0.31713	0.39773	-0.82917	0.859	0.430
holeboard	number of hole pokes by individual hole number, 20 min test, 12	-0.14503	0.65164	-0.14388	0.960	0.825
holeboard	number of hole pokes by individual hole number, 20 min test, 13	-0.59137	0.91929	-0.49711	0.835	0.524
holeboard	number of hole pokes by individual hole number, 20 min test, 14	-0.33372	0.65417	-0.43320	0.873	0.613
holeboard	number of hole pokes by individual hole number, 20 min test, 15	-0.23907	0.72727	-0.28378	0.914	0.744
holeboard	number of hole pokes by individual hole number, 20 min test, 16	-0.29184	1.0736	-0.24013	0.942	0.787
holeboard	total number of hole pokes, 20 min test	-3.9316	6.0514	-0.47433	0.749	0.520
light / dark	latency to enter dark zone, 20 min test	46.203	34.445	0.70797	0.619	0.187
light / dark	number of transitions between light and dark zones, 20 min test	-10.177	5.0915	-0.93973	0.278	0.0517
light / dark	percentage of total time in dark zone, 20 min test	5.5540	3.4909	1.1576	0.470	0.119
light / dark	percentage of total time in light zone, 20 min test	-5.5543	3.4910	-1.1629	0.469	0.119
light / dark	time mobile in dark zone, 20 min test	-4.1877	5.9697	-0.39247	0.755	0.487
light / dark	time mobile in light zone, 20 min test	3.6311	5.4597	-0.010816	0.747	0.509
light / dark	time spent in dark zone, 20 min test	21.566	43.489	0.53093	0.881	0.622
light / dark	time spent in light zone, 20 min test	-21.566	43.489	-0.53093	0.881	0.622
open field	average speed in center of arena, 20 min test	0.33131	0.29976	0.51074	0.622	0.274
open field	average speed in periphery of arena, 20 min test	0.088886	0.14883	-0.14891	0.750	0.553
open field	distance traveled habituation ratio, 20 min test	-0.45641	7.0470	0.0087270	0.975	0.949
open field	distance traveled in center of arena, 20 min test	15.795	85.107	-0.29629	0.922	0.854
open field	distance traveled in periphery of arena, 20 min test	133.05	163.61	0.10829	0.661	0.420
open field	distance traveled slope, 20 min test	1.8293	6.8036	0.23785	0.932	0.789
open field	distance traveled, 20 min test, 1st 5min	64.578	63.176	0.15842	0.555	0.312
open field	distance traveled, 20 min test, 2nd 5min	-26.528	60.972	-0.80284	0.832	0.665
open field	distance traveled, 20 min test, 3rd 5min	41.616	55.521	0.032900	0.696	0.457
open field	distance traveled, 20 min test, 4th 5min	70.623	53.842	0.32023	0.422	0.196
open field	number of clockwise revolution episodes, 20 min test	-0.62643	1.4021	-0.79138	0.872	0.657
open field	number of counter-clockwise revolution episodes, 20 min test	1.8631	1.6947	0.57294	0.558	0.277
open field	number of rears in 5 min bins, 20 min test, 1st 5min	3.4651	2.5311	0.75693	0.430	0.177
open field	number of rears in 5 min bins, 20 min test, 2nd 5min	0.43634	2.7629	-0.24338	0.949	0.875
open field	number of rears in 5 min bins, 20 min test, 3rd 5min	3.0269	3.1972	0.40630	0.619	0.348
open field	number of rears in 5 min bins, 20 min test, 4th 5min	2.9214	3.5102	0.31740	0.677	0.409
open field	percentage of total time in center of arena, 20 min test	-1.2058	2.9272	-0.50311	0.881	0.682
open field	percentage of total time in center of arena, slope, 20 min test	-4.4276	1.3885	-2.0357	0.137	0.00249
open field	percentage of total time in center, habituation ratio, 20 min test	-4.0585	1.3772	-1.7612	0.202	0.00487
open field	percentage of total time in corners of arena, 20 min test	-0.86232	2.9712	0.14483	0.910	0.773
open field	percentage of total time in corners, habituation ratio, 20 min test	3.1008	1.7059	1.0716	0.519	0.0751
open field	percentage of total time in corners, slope, 20 min test	3.0733	1.6934	1.0983	0.512	0.0757
open field	permanence time in center of arena, 20 min test	-14.465	35.129	-0.50311	0.882	0.682
open field	permanence time in corners of arena, 20 min test	-10.355	35.653	0.14348	0.910	0.773
open field	permanence time in periphery of arena, 20 min test	14.446	35.127	0.50311	0.881	0.683
open field	total distance traveled, 20 min test	148.39	198.41	-0.042304	0.674	0.458
open field	total number of rears, 20 min test	9.5953	10.350	0.31740	0.608	0.358
open field	whole arena average speed, 20 min test	0.12446	0.16526	-0.040961	0.668	0.455
open field	whole arena resting time, 20 min test	-4.7289	22.310	0.45045	0.903	0.833
open field	whole arena time spent mobile, 20 min test	-8.1341	8.0679	-0.92368	0.534	0.318
open field	whole arena time spent vertical, 20 min test	7.8797	7.7020	0.49398	0.616	0.311
SHIRPA	locomotor activity (number of squares in the arena the mouse moves into with all four paws in first 30 s of test)	-3.2285	1.5678	-1.1932	0.250	0.0482
startle / PPI	average baseline movement during background noise	-2.8035	1.3971	-1.7949	0.542	0.0518
startle / PPI	average of each corrected maximum percent pre-pulse inhibition value	0.036383	0.058393	0.23401	0.798	0.537
startle / PPI	average of each corrected percent pre-pulse inhibition value	0.045234	0.053181	0.37243	0.729	0.400
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	0.92930	7.2775	0.15970	0.994	0.899
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	3.4312	5.1785	0.28619	0.797	0.512
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	8.6079	5.1727	0.77518	0.353	0.104
startle / PPI	average startle response to full pulse (120 dB)	-32.605	42.685	-0.43278	0.684	0.450
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-31.594	42.616	-0.45287	0.685	0.463
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-36.504	32.433	-0.54493	0.487	0.267
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-39.647	26.266	-0.73236	0.334	0.139
startle / PPI	average startle response to pre-pulse, 74dB sound pressure level	0.51111	1.9292	0.43278	0.971	0.792
startle / PPI	average startle response to pre-pulse, 78dB sound pressure level	0.37292	1.5068	0.26146	0.961	0.806
startle / PPI	average startle response to pre-pulse, 82dB sound pressure level	1.1567	2.0004	0.37050	0.870	0.566
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	0.0099169	0.085446	0.13421	0.991	0.908
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	0.042834	0.054908	0.27193	0.731	0.440
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	0.095461	0.065408	0.57066	0.388	0.152
startle / PPI	corrected average startle response to full pulse (120 dB) minus average baseline movement during background noise	-29.521	42.600	-0.37952	0.723	0.492
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 74dB sound pressure level	-31.516	42.832	-0.44512	0.686	0.466
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 78dB sound pressure level	-36.418	32.657	-0.53520	0.485	0.272
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 82dB sound pressure level	-40.156	26.607	-0.71960	0.326	0.139
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	0.0054713	0.099613	0.086277	0.994	0.956
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	0.033716	0.061491	0.14490	0.808	0.587
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	0.10363	0.069428	0.58890	0.377	0.144
startle / PPI	corrected maximum startle response to full pulse (120 dB) minus maximum baseline movement during background noise	-112.35	149.75	-0.40829	0.686	0.458
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 74dB sound pressure level	-149.57	148.06	-0.59270	0.556	0.319
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 78dB sound pressure level	-145.01	121.39	-0.59604	0.454	0.239
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 82dB sound pressure level	-150.57	99.848	-0.74156	0.328	0.140
startle / PPI	maximum baseline movement during background noise	-7.9052	2.8554	-1.9969	0.309	0.00866
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	1.8509	8.3883	0.23833	0.980	0.827
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	3.2833	5.7100	0.19672	0.820	0.569
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	9.2021	5.9989	0.72870	0.401	0.133
startle / PPI	maximum startle response to full pulse (120 dB)	-121.33	149.84	-0.43740	0.654	0.423
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-152.99	147.05	-0.61456	0.540	0.305
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-146.19	120.62	-0.60443	0.451	0.233
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-148.23	99.093	-0.74156	0.339	0.143
startle / PPI	maximum startle response to pre-pulse, 74dB sound pressure level	-1.9229	5.1937	-0.52071	0.942	0.713
startle / PPI	maximum startle response to pre-pulse, 78dB sound pressure level	-0.39566	3.5265	-0.094718	0.991	0.911
startle / PPI	maximum startle response to pre-pulse, 82dB sound pressure level	4.1871	5.8551	0.56290	0.809	0.479

MULTIPLE (CATEGORICAL) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

Procedure	JaxKOMP-EAP Trait	Trait Effect	P-value
eye morphology	anterior chamber depth	1.0 %	1.0
eye morphology	bulging eye	1.0 %	1.00
eye morphology	cornea	3.0 %	1.00
eye morphology	cornea opacity	3.0 %	1.00
eye morphology	cornea vascularization	2.0 %	1.00
eye morphology	corneal deposits	1.0 %	1.00
eye morphology	corneal mineralization	1.0 %	1.00
eye morphology	corneal scleralization	6.0 %	0.0682
eye morphology	corneal ulcer	1.0 %	1.00
eye morphology	eye closure	1.0 %	1.0
eye morphology	eye hemorrhage or blood presence	6.0 %	0.0885
eye morphology	eyelid morphology	1.0 %	1.0
eye morphology	eyes (present, absent)	0.0 %	1.0
eye morphology	fusion between cornea and lens	17.0 %	0.0127
eye morphology	iris pigmentation	2.0 %	1.00
eye morphology	iris transillumination	1.0 %	1.00
eye morphology	irispupil	9.0 %	0.125
eye morphology	lacrimation	18.0 %	0.00589
eye morphology	lens	18.0 %	0.0195
eye morphology	lens opacity	17.0 %	0.0418
eye morphology	narrow eye opening	1.0 %	1.0
eye morphology	optic disc	17.0 %	0.0191
eye morphology	persistence of hyaloid vascular system	17.0 %	0.0516
eye morphology	pupil dilation	2.0 %	1.0
eye morphology	pupil light response	2.0 %	1.00
eye morphology	pupil position	9.0 %	0.140
eye morphology	pupil shape	3.0 %	1.00
eye morphology	retina	17.0 %	0.0348
eye morphology	retinal blood vessels	17.0 %	0.0120
eye morphology	retinal blood vessels pattern	17.0 %	0.0261
eye morphology	retinal blood vessels structure	17.0 %	0.0165
eye morphology	retinal pigmentation	17.0 %	0.0503
eye morphology	retinal structure	17.0 %	0.0174
eye morphology	synechia	17.0 %	0.0105
eye morphology	vitreous	17.0 %	0.0134
SHIRPA	activity body position	1.0 %	1.00
SHIRPA	aggression	1.0 %	1.0
SHIRPA	body length	0.0 %	1.00
SHIRPA	body position	0.0 %	1.0
SHIRPA	body thickness	0.0 %	1.0
SHIRPA	coat color abdomen	4.0 %	1.0
SHIRPA	coat color back	0.0 %	1.00
SHIRPA	coat color head	0.0 %	1.0
SHIRPA	coat color pattern abdomen	1.0 %	1.0
SHIRPA	coat color pattern back	0.0 %	1.0
SHIRPA	coat color pattern head	0.0 %	1.00
SHIRPA	coat hair abdomen texture appearance	2.0 %	1.0
SHIRPA	coat hair back texture appearance	0.0 %	1.0
SHIRPA	coat hair distribution abdomen	1.0 %	1.00
SHIRPA	coat hair distribution back	0.0 %	1.0
SHIRPA	coat hair distribution head	1.0 %	1.0
SHIRPA	coat hair head texture appearance	0.0 %	1.0
SHIRPA	contact righting	5.0 %	1.00
SHIRPA	ear morphology	0.0 %	1.0
SHIRPA	fat distribution	0.0 %	1.00
SHIRPA	forelimb digit number	0.0 %	1.00
SHIRPA	forelimb digit position	0.0 %	1.0
SHIRPA	forelimb digit shape	0.0 %	1.0
SHIRPA	forelimb digit size	0.0 %	1.0
SHIRPA	forelimb footpads	0.0 %	1.0
SHIRPA	forelimb nail length	0.0 %	1.0
SHIRPA	forelimb nail number	0.0 %	1.0
SHIRPA	forelimb nail position	0.0 %	1.0
SHIRPA	forelimb nail shape	0.0 %	1.0
SHIRPA	forelimbs position	0.0 %	1.0
SHIRPA	forelimbs shape	0.0 %	1.0
SHIRPA	forelimbs size	0.0 %	1.0
SHIRPA	forepaw position	0.0 %	1.0
SHIRPA	forepaw shape	0.0 %	1.0
SHIRPA	forepaw size	0.0 %	1.0
SHIRPA	gait (fluidity)	0.0 %	1.00
SHIRPA	genitalia morphology	0.0 %	1.00
SHIRPA	genitalia presence	0.0 %	1.0
SHIRPA	genitalia size	0.0 %	1.0
SHIRPA	head bobbing	0.0 %	1.0
SHIRPA	head morphology	0.0 %	1.0
SHIRPA	head size	0.0 %	1.00
SHIRPA	hindlimb digit number	0.0 %	1.00
SHIRPA	hindlimb digit position	0.0 %	1.0
SHIRPA	hindlimb digit shape	0.0 %	1.0
SHIRPA	hindlimb digit size	0.0 %	1.00
SHIRPA	hindlimb nail length	0.0 %	1.00
SHIRPA	hindlimb nail number	0.0 %	1.00
SHIRPA	hindlimb nail position	0.0 %	1.0
SHIRPA	hindlimb nail shape	0.0 %	1.0
SHIRPA	hindlimbs footpads	0.0 %	1.0
SHIRPA	hindlimbs position	0.0 %	1.0
SHIRPA	hindlimbs shape	0.0 %	1.0
SHIRPA	hindlimbs size	0.0 %	1.0
SHIRPA	hindpaw position	0.0 %	1.0
SHIRPA	hindpaw shape	0.0 %	1.0
SHIRPA	hindpaw size	0.0 %	1.0
SHIRPA	limb grasp	1.0 %	1.0
SHIRPA	lower lip morphology	0.0 %	1.0
SHIRPA	lower teeth appearance	0.0 %	1.00
SHIRPA	mouth morphology	0.0 %	1.00
SHIRPA	salivation	0.0 %	1.0
SHIRPA	skin color back paws	0.0 %	1.0
SHIRPA	skin color ear	0.0 %	1.0
SHIRPA	skin color front paws	0.0 %	1.0
SHIRPA	skin color snout	0.0 %	1.0
SHIRPA	skin color tail	0.0 %	1.0
SHIRPA	skin color whole body	0.0 %	1.0
SHIRPA	skin texture back paw	0.0 %	1.0
SHIRPA	skin texture ear	0.0 %	1.0
SHIRPA	skin texture front paws	0.0 %	1.0
SHIRPA	skin texture snout	0.0 %	1.0
SHIRPA	skin texture tail	0.0 %	1.0
SHIRPA	skin texture whole body	0.0 %	1.00
SHIRPA	snout size	0.0 %	1.0
SHIRPA	startle response	0.0 %	1.00
SHIRPA	tail curvature	0.0 %	1.0
SHIRPA	tail elevation	1.0 %	1.0
SHIRPA	tail length	0.0 %	1.00
SHIRPA	tail morphology	0.0 %	1.00
SHIRPA	tail presence	0.0 %	1.0
SHIRPA	tail shape	0.0 %	1.00
SHIRPA	tail thickness	0.0 %	1.0
SHIRPA	teeth presence	0.0 %	1.00
SHIRPA	transfer arousal	1.0 %	1.0
SHIRPA	tremor	0.0 %	1.00
SHIRPA	trunk curl	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	0.0 %	1.00
SHIRPA	upper lip morphology	0.0 %	1.0
SHIRPA	upper teeth appearance	0.0 %	1.00
SHIRPA	vibrissae appearance	1.0 %	1.0
SHIRPA	vibrissae presence	2.0 %	1.0
SHIRPA	vocalization	2.0 %	1.0

GENOTYPE CORRELATION PLOT

Correlate Slc25a48^em1(IMPC)J/Mmjax -/- with genotype:

This genotype correlation visualization can include both EAP and LAP measures.