MPD: JaxKOMP-EAP genotype: Gm17215<sup>em2(n-TAagc16)J</sup> -/-

JaxKOMP-EAP effect sizes: Gm17215^{em2(n-TAagc16)J} -/- Gene Gm17215

MULTIPLE (NUMERIC) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

Procedure	JaxKOMP-EAP Trait	Trait Effect	Trait Effect SE	Trait Effect RankZ	Adjusted p-value	Unadjusted p-value
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 6 kHz pip	-7.5429	1.8196	-1.8658	0.0701	0.00115
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 12 kHz pip	-10.754	3.3953	-1.7828	0.182	0.00742
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 18 kHz pip	-0.73912	3.0697	-0.35452	0.940	0.813
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 24 kHz pip	-9.4873	4.5335	-1.5087	0.331	0.0566
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 30 kHz pip	2.7083	3.8584	0.39864	0.789	0.494
body composition	body length	0.20397	0.059689	2.1755	0.0314	0.00226
body composition	body weight (at time of DXA)	-0.64750	0.67342	-0.39113	0.564	0.346
body composition	bone area, whole body scan, head excluded	0.56928	0.18373	2.3551	0.0526	0.00490
body composition	bone mineral content of whole body scan, head excluded	0.043753	0.012951	2.2577	0.0351	0.00249
body composition	bone mineral content to body weight ratio	0.0013043	0.00048616	1.8281	0.0911	0.0130
body composition	bone mineral density of whole body scan, head excluded	0.0016502	0.00059804	1.7104	0.100	0.0109
body composition	fat tissue mass of whole body scan, head excluded	-1.3809	0.34391	-2.1496	0.0127	0.000507
body composition	fat tissue mass to body weight ratio	-0.046274	0.011902	-2.0735	0.0144	0.000699
body composition	lean tissue mass of whole body scan, head excluded	1.3907	0.35771	2.1360	0.0279	0.000699
body composition	lean tissue mass to body weight ratio	0.044896	0.010324	2.0179	0.00998	0.000218
body composition	percent fat, whole body scan, head excluded	-4.5644	1.1346	-2.1228	0.0123	0.000497
body composition	ratio of soft-tissue attenuation coefficients	0.0050034	0.0012577	2.0966	0.0132	0.000557
body composition	tissue area	-0.062346	0.19796	-0.030073	0.913	0.756
body composition	total tissue mass, whole body scan, head excluded	0.0097532	0.23987	-0.18398	0.983	0.968
clinical blood chemistry	alanine transaminase (plasma ALT)	7.0273	7.9458	0.54516	0.724	0.384
clinical blood chemistry	albumin (plasma Alb)	-0.58001	0.30736	-0.73948	0.327	0.0692
clinical blood chemistry	alkaline phosphatase (plasma ALP)	5.0764	2.8719	0.41781	0.276	0.0880
clinical blood chemistry	aspartate transaminase (plasma AST)	5.0657	9.3793	0.24486	0.832	0.593
clinical blood chemistry	aspartate transaminase to alanine transaminase ratio (plasma AST:ALT)	-0.068210	0.17497	-0.22618	0.910	0.700
clinical blood chemistry	blood urea nitrogen (BUN)	-0.92894	1.4862	-0.41349	0.753	0.537
clinical blood chemistry	calcium (plasma Ca)	-0.044306	0.067515	0.030573	0.718	0.517
clinical blood chemistry	creatinine (plasma)	-0.023761	0.021416	-0.42625	0.524	0.276
clinical blood chemistry	glucose (plasma GLU, no fast)	-10.679	12.454	-0.12530	0.603	0.398
clinical blood chemistry	HDL cholesterol (plasma HDL)	-0.41095	2.6135	-0.43021	0.962	0.876
clinical blood chemistry	HDL cholesterol to total cholesterol ratio	0.0088301	0.010464	0.34779	0.715	0.406
clinical blood chemistry	phosphorus (plasma phosphate)	0.31717	0.50461	0.43595	0.774	0.535
clinical blood chemistry	total bilirubin (plasma TBIL)	-0.0030167	0.0067133	-0.23638	0.869	0.657
clinical blood chemistry	total cholesterol (plasma CHOL, no fast)	-1.6131	3.3722	-0.52261	0.857	0.636
clinical blood chemistry	total protein (plasma TP)	-0.32530	0.55574	-0.31939	0.769	0.563
clinical blood chemistry	triglyceride (plasma TG, no fast)	-6.3305	7.9966	-0.13923	0.697	0.435
glucose tolerance test	amount glucose injected	0.68757	2.5476	0.57543	0.934	0.791
glucose tolerance test	plasma glucose, 0min	2.0980	5.5992	-0.019220	0.849	0.713
glucose tolerance test	plasma glucose, 15min	0.74012	20.150	0.11833	0.987	0.971
glucose tolerance test	plasma glucose, 30min	14.676	29.000	0.55265	0.837	0.620
glucose tolerance test	plasma glucose, 60min	-1.2349	19.715	0.090725	0.977	0.951
glucose tolerance test	plasma glucose, 120min	-9.2928	9.4447	-0.76983	0.632	0.339
grip strength	body weight (at time of grip strength test)	0.50477	0.66890	0.68729	0.705	0.529
grip strength	forelimb and hindlimb grip strength (mean of trials), average	-7.3442	18.823	-0.29315	0.859	0.734
grip strength	forelimb and hindlimb grip strength (mean of trials), average normalized to bw	-0.41967	0.94546	-0.42648	0.832	0.701
grip strength	forelimb and hindlimb grip strength by trial, trial1	-12.909	23.423	-0.61811	0.849	0.637
grip strength	forelimb and hindlimb grip strength by trial, trial2	0.39161	19.124	0.25545	0.992	0.986
grip strength	forelimb and hindlimb grip strength by trial, trial3	-5.6742	14.990	-0.17369	0.891	0.741
grip strength	forelimb grip strength (mean of trials), average	-13.777	5.7779	-1.3786	0.368	0.140
grip strength	forelimb grip strength (mean of trials), average normalized to bw	-0.65704	0.30461	-1.3208	0.418	0.164
grip strength	forelimb grip strength by trial, trial1	-17.966	7.6313	-1.6409	0.454	0.143
grip strength	forelimb grip strength by trial, trial2	-2.4324	6.2848	-0.043582	0.907	0.736
grip strength	forelimb grip strength by trial, trial3	-20.661	6.8513	-1.8001	0.357	0.0946
heart weight	heart weight, normalized to body weight	0.28707	0.090576	0.54388	0.0271	0.00301
heart weight	heart weight, weight	5.1595	2.7996	0.29121	0.228	0.0732
hematology	basophil differential (percent of total WBC)	-0.038528	0.029199	-0.57680	0.633	0.197
hematology	calculated hemoglobin (cHGB)	0.19762	0.21717	0.33836	0.643	0.370
hematology	eosinophil differential (percent of total WBC)	-0.39527	0.22819	-1.0109	0.462	0.0935
hematology	hematocrit (HCT)	0.40325	0.54950	0.060174	0.707	0.469
hematology	hemoglobin concentration distribution width (HDW)	0.018420	0.021018	0.49392	0.689	0.388
hematology	large unstained cells (percent of total WBC)	0.14971	0.056609	0.96327	0.181	0.0129
hematology	lymphocyte differential (percent of total WBC)	1.7372	1.3489	0.63302	0.460	0.207
hematology	mean corpuscular hemoglobin (CHr)	-0.00030567	0.052379	0.024198	0.998	0.995
hematology	mean platelet volume (MPV)	-0.10909	0.10634	-0.86412	0.541	0.313
hematology	mean RBC corpuscular hemoglobin (MCH)	-0.066394	0.13123	-0.27789	0.840	0.617
hematology	mean RBC corpuscular hemoglobin concentration (MCHC)	0.070779	0.30937	0.19016	0.945	0.821
hematology	mean RBC corpuscular volume (MCV)	-0.25883	0.24099	-0.47515	0.522	0.291
hematology	measured hemoglobin (mHGB)	0.14829	0.20741	0.12545	0.723	0.480
hematology	monocyte differential (percent of total WBC)	-0.027706	0.16038	0.11644	0.948	0.864
hematology	neutrophil differential (percent of total WBC)	-1.3472	1.1612	-0.62138	0.506	0.255
hematology	platelet count (PLT; units per volume x 10³)	61.981	51.096	0.86483	0.603	0.235
hematology	RBC corpuscular distribution width (RDW)	0.11871	0.11029	0.39886	0.559	0.290
hematology	RBC corpuscular hemoglobin concentration mean (CHCM)	0.22877	0.20309	0.55257	0.528	0.269
hematology	red blood cell count (RBC; per volume x 10⁶)	0.11805	0.15528	0.17882	0.694	0.453
hematology	reticulocyte count (Retic; units per volume x 10⁹)	-10.562	13.021	-0.38347	0.766	0.423
hematology	reticulocyte differential (percent of total RBC)	-0.16592	0.11705	-0.51327	0.520	0.166
hematology	white blood cell count (WBC; units per volume x 10³)	0.40284	0.62523	0.45232	0.701	0.524
holeboard	number of hole pokes by individual hole number, 20 min test, 1	-0.97296	1.2391	-0.92387	0.802	0.438
holeboard	number of hole pokes by individual hole number, 20 min test, 2	0.052015	0.98381	0.21863	0.990	0.958
holeboard	number of hole pokes by individual hole number, 20 min test, 3	0.66533	0.61932	1.0800	0.780	0.290
holeboard	number of hole pokes by individual hole number, 20 min test, 4	0.47473	0.83383	0.54485	0.870	0.573
holeboard	number of hole pokes by individual hole number, 20 min test, 5	-0.044451	0.76072	0.041367	0.985	0.954
holeboard	number of hole pokes by individual hole number, 20 min test, 6	0.74921	0.58764	1.5729	0.819	0.211
holeboard	number of hole pokes by individual hole number, 20 min test, 7	0.11068	0.49046	0.30467	0.983	0.823
holeboard	number of hole pokes by individual hole number, 20 min test, 8	0.77729	0.57512	1.3518	0.729	0.185
holeboard	number of hole pokes by individual hole number, 20 min test, 9	0.077219	0.55391	0.25091	0.986	0.890
holeboard	number of hole pokes by individual hole number, 20 min test, 10	0.61007	0.31589	1.4402	0.664	0.0618
holeboard	number of hole pokes by individual hole number, 20 min test, 11	0.80623	0.45808	1.6396	0.673	0.0871
holeboard	number of hole pokes by individual hole number, 20 min test, 12	0.60440	0.57756	1.0507	0.738	0.303
holeboard	number of hole pokes by individual hole number, 20 min test, 13	1.0440	0.73975	1.0926	0.578	0.167
holeboard	number of hole pokes by individual hole number, 20 min test, 14	0.97216	0.68365	1.4709	0.598	0.164
holeboard	number of hole pokes by individual hole number, 20 min test, 15	1.7198	0.60933	2.2327	0.300	0.00781
holeboard	number of hole pokes by individual hole number, 20 min test, 16	1.7231	0.97711	1.4860	0.504	0.0866
holeboard	total number of hole pokes, 20 min test	8.8926	6.1829	1.2175	0.436	0.159
light / dark	latency to enter dark zone, 20 min test	83.220	47.502	1.2890	0.519	0.0883
light / dark	number of transitions between light and dark zones, 20 min test	-1.6668	9.1993	-0.043278	0.943	0.857
light / dark	percentage of total time in dark zone, 20 min test	-1.1820	3.5936	-0.079853	0.914	0.744
light / dark	percentage of total time in light zone, 20 min test	1.1820	3.5936	0.077141	0.916	0.744
light / dark	time mobile in dark zone, 20 min test	6.0191	12.951	0.30905	0.844	0.645
light / dark	time mobile in light zone, 20 min test	28.351	9.9395	1.2350	0.0643	0.00715
light / dark	time spent in dark zone, 20 min test	-77.980	42.455	-0.93344	0.434	0.0745
light / dark	time spent in light zone, 20 min test	77.980	42.455	0.93344	0.434	0.0745
open field	average speed in center of arena, 20 min test	-0.22714	0.27521	-0.48490	0.736	0.413
open field	average speed in periphery of arena, 20 min test	0.093261	0.14002	-0.12993	0.723	0.509
open field	distance traveled habituation ratio, 20 min test	-10.920	7.3377	-0.92574	0.452	0.143
open field	distance traveled in center of arena, 20 min test	31.540	119.05	-0.19798	0.893	0.792
open field	distance traveled in periphery of arena, 20 min test	69.669	123.83	-0.15977	0.765	0.576
open field	distance traveled slope, 20 min test	-11.683	6.8074	-1.0206	0.366	0.0926
open field	distance traveled, 20 min test, 1st 5min	77.699	67.925	0.27392	0.504	0.258
open field	distance traveled, 20 min test, 2nd 5min	53.781	47.546	0.093446	0.497	0.264
open field	distance traveled, 20 min test, 3rd 5min	-3.3564	58.455	-0.48189	0.989	0.954
open field	distance traveled, 20 min test, 4th 5min	-22.180	52.543	-0.71855	0.837	0.675
open field	number of clockwise revolution episodes, 20 min test	0.84953	1.1591	0.080686	0.771	0.467
open field	number of counter-clockwise revolution episodes, 20 min test	-1.4437	1.2791	-1.1913	0.550	0.265
open field	number of rears in 5 min bins, 20 min test, 1st 5min	-0.52751	2.2564	-0.36385	0.925	0.816
open field	number of rears in 5 min bins, 20 min test, 2nd 5min	2.6149	2.6264	0.32447	0.610	0.324
open field	number of rears in 5 min bins, 20 min test, 3rd 5min	0.90745	2.6583	-0.12586	0.867	0.734
open field	number of rears in 5 min bins, 20 min test, 4th 5min	1.4755	2.9315	-0.026184	0.810	0.617
open field	percentage of total time in center of arena, 20 min test	1.5603	3.4072	0.15026	0.866	0.649
open field	percentage of total time in center of arena, slope, 20 min test	-0.41344	1.5452	-0.11369	0.955	0.790
open field	percentage of total time in center, habituation ratio, 20 min test	-0.64610	1.5145	-0.21169	0.902	0.672
open field	percentage of total time in corners of arena, 20 min test	-3.5510	4.2270	-0.32730	0.692	0.405
open field	percentage of total time in corners, habituation ratio, 20 min test	3.9148	1.4779	1.4028	0.246	0.0110
open field	percentage of total time in corners, slope, 20 min test	3.5510	1.4889	1.3117	0.324	0.0212
open field	permanence time in center of arena, 20 min test	18.715	40.885	0.15162	0.866	0.649
open field	permanence time in corners of arena, 20 min test	-42.615	50.723	-0.32872	0.692	0.405
open field	permanence time in periphery of arena, 20 min test	-18.732	40.879	-0.15162	0.866	0.649
open field	total distance traveled, 20 min test	108.73	190.12	-0.17066	0.756	0.570
open field	total number of rears, 20 min test	4.5351	9.2314	-0.028870	0.804	0.625
open field	whole arena average speed, 20 min test	0.090283	0.15864	-0.17066	0.757	0.572
open field	whole arena resting time, 20 min test	-9.5699	20.039	0.27253	0.783	0.635
open field	whole arena time spent mobile, 20 min test	9.5644	20.021	-0.086706	0.786	0.635
open field	whole arena time spent vertical, 20 min test	0.85777	8.3062	-0.042304	0.967	0.918
SHIRPA	locomotor activity (number of squares in the arena the mouse moves into with all four paws in first 30 s of test)	1.9783	1.9135	1.0293	0.614	0.311
startle / PPI	average baseline movement during background noise	0.25330	1.1414	0.26726	0.971	0.825
startle / PPI	average of each corrected maximum percent pre-pulse inhibition value	0.032446	0.057815	0.18816	0.814	0.577
startle / PPI	average of each corrected percent pre-pulse inhibition value	0.033545	0.056072	0.25306	0.829	0.552
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-0.13556	6.5188	0.041345	0.995	0.983
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	4.0151	6.3897	0.34065	0.805	0.532
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	2.9379	5.5095	0.21963	0.838	0.596
startle / PPI	average startle response to full pulse (120 dB)	-0.91667	37.005	0.18958	0.991	0.980
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	5.3637	37.879	0.31256	0.953	0.888
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-4.2618	37.389	0.090496	0.951	0.910
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	0.14949	31.076	0.19529	0.999	0.996
startle / PPI	average startle response to pre-pulse, 74dB sound pressure level	1.3375	1.2632	0.85326	0.785	0.294
startle / PPI	average startle response to pre-pulse, 78dB sound pressure level	1.6707	1.5686	0.93692	0.809	0.291
startle / PPI	average startle response to pre-pulse, 82dB sound pressure level	3.0969	1.7847	1.0790	0.501	0.0883
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	0.0035206	0.068124	0.072221	0.995	0.959
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	0.050543	0.068442	0.33956	0.744	0.463
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	0.046749	0.064183	0.21904	0.714	0.470
startle / PPI	corrected average startle response to full pulse (120 dB) minus average baseline movement during background noise	-0.93116	36.979	0.19386	0.992	0.980
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 74dB sound pressure level	4.1739	38.217	0.29057	0.962	0.913
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 78dB sound pressure level	-5.9325	37.202	0.065199	0.930	0.874
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 82dB sound pressure level	-2.9642	31.627	0.12150	0.963	0.926
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	0.0088396	0.068636	0.11867	0.989	0.898
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	0.052631	0.070026	0.32972	0.746	0.456
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	0.036413	0.068891	0.095475	0.799	0.599
startle / PPI	corrected maximum startle response to full pulse (120 dB) minus maximum baseline movement during background noise	-35.042	134.14	-0.020318	0.917	0.795
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 74dB sound pressure level	-13.721	134.26	0.11162	0.956	0.919
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 78dB sound pressure level	-50.727	137.32	-0.087683	0.830	0.713
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 82dB sound pressure level	-20.859	119.90	0.058180	0.925	0.863
startle / PPI	maximum baseline movement during background noise	2.0935	2.9184	0.66791	0.851	0.476
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	0.51335	6.5298	0.10457	1.00	0.938
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	4.7135	6.6269	0.33916	0.771	0.480
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	2.3799	6.2117	0.077841	0.866	0.703
startle / PPI	maximum startle response to full pulse (120 dB)	-33.569	134.00	-0.013311	0.918	0.803
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-8.4085	133.10	0.13987	0.970	0.950
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-46.757	137.55	-0.082058	0.846	0.735
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-12.155	118.53	0.11021	0.955	0.919
startle / PPI	maximum startle response to pre-pulse, 74dB sound pressure level	5.7506	3.8403	1.4169	0.642	0.140
startle / PPI	maximum startle response to pre-pulse, 78dB sound pressure level	4.1143	3.8069	0.99042	0.755	0.285
startle / PPI	maximum startle response to pre-pulse, 82dB sound pressure level	8.7043	4.5989	1.1466	0.400	0.0637

MULTIPLE (CATEGORICAL) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

Procedure	JaxKOMP-EAP Trait	Sex	Trait Effect	P-value
eye morphology	anterior chamber depth	females	1.0 %	1.0
eye morphology	anterior chamber depth	males	0.0 %	1.0
eye morphology	anterior chamber depth	both	1.0 %	1.0
eye morphology	bulging eye	females	1.0 %	1.0
eye morphology	bulging eye	males	0.0 %	1.0
eye morphology	bulging eye	both	1.0 %	1.00
eye morphology	cornea	females	13.0 %	0.155
eye morphology	cornea	males	2.0 %	1.0
eye morphology	cornea	both	7.0 %	0.205
eye morphology	cornea opacity	females	5.0 %	1.0
eye morphology	cornea opacity	males	1.0 %	1.0
eye morphology	cornea opacity	both	3.0 %	1.00
eye morphology	cornea vascularization	females	3.0 %	1.0
eye morphology	cornea vascularization	males	1.0 %	1.0
eye morphology	cornea vascularization	both	2.0 %	1.00
eye morphology	corneal deposits	females	2.0 %	1.0
eye morphology	corneal deposits	males	1.0 %	1.0
eye morphology	corneal deposits	both	1.0 %	1.00
eye morphology	corneal mineralization	females	2.0 %	1.0
eye morphology	corneal mineralization	males	1.0 %	1.0
eye morphology	corneal mineralization	both	1.0 %	1.0
eye morphology	corneal scleralization	females	3.0 %	1.0
eye morphology	corneal scleralization	males	1.0 %	1.0
eye morphology	corneal scleralization	both	2.0 %	1.00
eye morphology	corneal ulcer	females	1.0 %	1.0
eye morphology	corneal ulcer	males	1.0 %	1.0
eye morphology	corneal ulcer	both	1.0 %	1.0
eye morphology	eye closure	females	1.0 %	1.0
eye morphology	eye closure	males	0.0 %	1.0
eye morphology	eye closure	both	1.0 %	1.00
eye morphology	eye hemorrhage or blood presence	females	2.0 %	1.0
eye morphology	eye hemorrhage or blood presence	males	1.0 %	1.0
eye morphology	eye hemorrhage or blood presence	both	1.0 %	1.00
eye morphology	eyelid morphology	females	1.0 %	1.0
eye morphology	eyelid morphology	males	0.0 %	1.0
eye morphology	eyelid morphology	both	1.0 %	1.00
eye morphology	eyes (present, absent)	females	1.0 %	1.0
eye morphology	eyes (present, absent)	males	0.0 %	1.0
eye morphology	eyes (present, absent)	both	0.0 %	1.00
eye morphology	fusion between cornea and lens	females	4.0 %	1.0
eye morphology	fusion between cornea and lens	males	2.0 %	1.0
eye morphology	fusion between cornea and lens	both	3.0 %	1.00
eye morphology	iris pigmentation	females	2.0 %	1.0
eye morphology	iris pigmentation	males	1.0 %	1.0
eye morphology	iris pigmentation	both	2.0 %	1.00
eye morphology	iris transillumination	females	2.0 %	1.0
eye morphology	iris transillumination	males	1.0 %	1.00
eye morphology	iris transillumination	both	1.0 %	1.00
eye morphology	irispupil	females	4.0 %	1.0
eye morphology	irispupil	males	3.0 %	1.0
eye morphology	irispupil	both	3.0 %	1.00
eye morphology	lacrimation	females	3.0 %	1.00
eye morphology	lacrimation	males	2.0 %	1.00
eye morphology	lacrimation	both	3.0 %	1.0
eye morphology	lens	females	10.0 %	1.0
eye morphology	lens	males	8.0 %	1.00
eye morphology	lens	both	9.0 %	1.00
eye morphology	lens opacity	females	9.0 %	1.0
eye morphology	lens opacity	males	6.0 %	1.00
eye morphology	lens opacity	both	7.0 %	1.00
eye morphology	narrow eye opening	females	2.0 %	1.00
eye morphology	narrow eye opening	males	1.0 %	1.0
eye morphology	narrow eye opening	both	1.0 %	1.00
eye morphology	optic disc	females	4.0 %	1.0
eye morphology	optic disc	males	2.0 %	1.00
eye morphology	optic disc	both	3.0 %	1.00
eye morphology	persistence of hyaloid vascular system	females	14.0 %	1.0
eye morphology	persistence of hyaloid vascular system	males	5.0 %	1.0
eye morphology	persistence of hyaloid vascular system	both	9.0 %	1.00
eye morphology	pupil dilation	females	2.0 %	1.0
eye morphology	pupil dilation	males	1.0 %	1.00
eye morphology	pupil dilation	both	2.0 %	1.00
eye morphology	pupil light response	females	2.0 %	1.0
eye morphology	pupil light response	males	1.0 %	1.0
eye morphology	pupil light response	both	2.0 %	1.00
eye morphology	pupil position	females	4.0 %	1.0
eye morphology	pupil position	males	3.0 %	1.0
eye morphology	pupil position	both	4.0 %	1.00
eye morphology	pupil shape	females	3.0 %	1.0
eye morphology	pupil shape	males	2.0 %	1.0
eye morphology	pupil shape	both	3.0 %	1.00
eye morphology	retina	females	12.0 %	0.412
eye morphology	retina	males	11.0 %	0.498
eye morphology	retina	both	12.0 %	0.395
eye morphology	retinal blood vessels	females	4.0 %	1.0
eye morphology	retinal blood vessels	males	2.0 %	1.0
eye morphology	retinal blood vessels	both	3.0 %	1.00
eye morphology	retinal blood vessels pattern	females	5.0 %	1.0
eye morphology	retinal blood vessels pattern	males	2.0 %	1.00
eye morphology	retinal blood vessels pattern	both	4.0 %	1.00
eye morphology	retinal blood vessels structure	females	4.0 %	1.0
eye morphology	retinal blood vessels structure	males	2.0 %	1.0
eye morphology	retinal blood vessels structure	both	3.0 %	1.00
eye morphology	retinal pigmentation	females	12.0 %	1.0
eye morphology	retinal pigmentation	males	14.0 %	1.0
eye morphology	retinal pigmentation	both	13.0 %	1.00
eye morphology	retinal structure	females	4.0 %	1.0
eye morphology	retinal structure	males	2.0 %	1.00
eye morphology	retinal structure	both	3.0 %	1.00
eye morphology	synechia	females	4.0 %	1.0
eye morphology	synechia	males	2.0 %	1.00
eye morphology	synechia	both	3.0 %	1.00
eye morphology	vitreous	females	4.0 %	1.0
eye morphology	vitreous	males	2.0 %	1.0
eye morphology	vitreous	both	3.0 %	1.00
SHIRPA	activity body position	females	24.0 %	0.00297
SHIRPA	activity body position	males	24.0 %	0.00385
SHIRPA	activity body position	both	24.0 %	0.0000526
SHIRPA	aggression	females	12.0 %	0.0404
SHIRPA	aggression	males	24.0 %	0.00128
SHIRPA	aggression	both	18.0 %	0.000109
SHIRPA	body length	females	0.0 %	1.0
SHIRPA	body length	males	0.0 %	1.00
SHIRPA	body length	both	0.0 %	1.00
SHIRPA	body position	females	12.0 %	0.00301
SHIRPA	body position	males	1.0 %	1.0
SHIRPA	body position	both	6.0 %	0.00460
SHIRPA	body thickness	females	1.0 %	1.0
SHIRPA	body thickness	males	0.0 %	1.0
SHIRPA	body thickness	both	0.0 %	1.0
SHIRPA	coat color abdomen	females	22.0 %	0.0306
SHIRPA	coat color abdomen	males	71.0 %	7.03e-8
SHIRPA	coat color abdomen	both	46.0 %	2.97e-8
SHIRPA	coat color back	females	0.0 %	1.0
SHIRPA	coat color back	males	0.0 %	1.00
SHIRPA	coat color back	both	0.0 %	1.00
SHIRPA	coat color head	females	0.0 %	1.0
SHIRPA	coat color head	males	0.0 %	1.00
SHIRPA	coat color head	both	0.0 %	1.0
SHIRPA	coat color pattern abdomen	females	1.0 %	1.0
SHIRPA	coat color pattern abdomen	males	1.0 %	1.0
SHIRPA	coat color pattern abdomen	both	1.0 %	1.0
SHIRPA	coat color pattern back	females	0.0 %	1.0
SHIRPA	coat color pattern back	males	0.0 %	1.00
SHIRPA	coat color pattern back	both	0.0 %	1.0
SHIRPA	coat color pattern head	females	0.0 %	1.0
SHIRPA	coat color pattern head	males	0.0 %	1.0
SHIRPA	coat color pattern head	both	0.0 %	1.00
SHIRPA	coat hair abdomen texture appearance	females	2.0 %	1.0
SHIRPA	coat hair abdomen texture appearance	males	35.0 %	0.000848
SHIRPA	coat hair abdomen texture appearance	both	17.0 %	0.00403
SHIRPA	coat hair back texture appearance	females	0.0 %	1.0
SHIRPA	coat hair back texture appearance	males	0.0 %	1.0
SHIRPA	coat hair back texture appearance	both	0.0 %	1.0
SHIRPA	coat hair distribution abdomen	females	0.0 %	1.0
SHIRPA	coat hair distribution abdomen	males	36.0 %	0.0000894
SHIRPA	coat hair distribution abdomen	both	18.0 %	0.000167
SHIRPA	coat hair distribution back	females	0.0 %	1.0
SHIRPA	coat hair distribution back	males	0.0 %	1.0
SHIRPA	coat hair distribution back	both	0.0 %	1.0
SHIRPA	coat hair distribution head	females	1.0 %	1.00
SHIRPA	coat hair distribution head	males	1.0 %	1.0
SHIRPA	coat hair distribution head	both	1.0 %	1.0
SHIRPA	coat hair head texture appearance	females	0.0 %	1.00
SHIRPA	coat hair head texture appearance	males	0.0 %	1.0
SHIRPA	coat hair head texture appearance	both	0.0 %	1.0
SHIRPA	contact righting	females	5.0 %	1.0
SHIRPA	contact righting	males	5.0 %	1.00
SHIRPA	contact righting	both	5.0 %	1.00
SHIRPA	ear morphology	females	0.0 %	1.0
SHIRPA	ear morphology	males	0.0 %	1.0
SHIRPA	ear morphology	both	0.0 %	1.0
SHIRPA	fat distribution	females	0.0 %	1.0
SHIRPA	fat distribution	males	0.0 %	1.0
SHIRPA	fat distribution	both	0.0 %	1.00
SHIRPA	forelimb digit number	females	0.0 %	1.00
SHIRPA	forelimb digit number	males	0.0 %	1.0
SHIRPA	forelimb digit number	both	0.0 %	1.00
SHIRPA	forelimb digit position	females	0.0 %	1.0
SHIRPA	forelimb digit position	males	0.0 %	1.0
SHIRPA	forelimb digit position	both	0.0 %	1.0
SHIRPA	forelimb digit shape	females	0.0 %	1.0
SHIRPA	forelimb digit shape	males	0.0 %	1.0
SHIRPA	forelimb digit shape	both	0.0 %	1.0
SHIRPA	forelimb digit size	females	0.0 %	1.0
SHIRPA	forelimb digit size	males	0.0 %	1.0
SHIRPA	forelimb digit size	both	0.0 %	1.0
SHIRPA	forelimb footpads	females	0.0 %	1.0
SHIRPA	forelimb footpads	males	0.0 %	1.0
SHIRPA	forelimb footpads	both	0.0 %	1.0
SHIRPA	forelimb nail length	females	0.0 %	1.0
SHIRPA	forelimb nail length	males	0.0 %	1.0
SHIRPA	forelimb nail length	both	0.0 %	1.0
SHIRPA	forelimb nail number	females	0.0 %	1.0
SHIRPA	forelimb nail number	males	0.0 %	1.0
SHIRPA	forelimb nail number	both	0.0 %	1.0
SHIRPA	forelimb nail position	females	0.0 %	1.0
SHIRPA	forelimb nail position	males	0.0 %	1.0
SHIRPA	forelimb nail position	both	0.0 %	1.0
SHIRPA	forelimb nail shape	females	0.0 %	1.0
SHIRPA	forelimb nail shape	males	0.0 %	1.0
SHIRPA	forelimb nail shape	both	0.0 %	1.0
SHIRPA	forelimbs position	females	0.0 %	1.0
SHIRPA	forelimbs position	males	0.0 %	1.0
SHIRPA	forelimbs position	both	0.0 %	1.0
SHIRPA	forelimbs shape	females	0.0 %	1.0
SHIRPA	forelimbs shape	males	0.0 %	1.0
SHIRPA	forelimbs shape	both	0.0 %	1.0
SHIRPA	forelimbs size	females	0.0 %	1.0
SHIRPA	forelimbs size	males	0.0 %	1.0
SHIRPA	forelimbs size	both	0.0 %	1.0
SHIRPA	forepaw position	females	0.0 %	1.0
SHIRPA	forepaw position	males	0.0 %	1.0
SHIRPA	forepaw position	both	0.0 %	1.0
SHIRPA	forepaw shape	females	0.0 %	1.0
SHIRPA	forepaw shape	males	0.0 %	1.0
SHIRPA	forepaw shape	both	0.0 %	1.0
SHIRPA	forepaw size	females	0.0 %	1.0
SHIRPA	forepaw size	males	0.0 %	1.0
SHIRPA	forepaw size	both	0.0 %	1.0
SHIRPA	gait (fluidity)	females	0.0 %	1.0
SHIRPA	gait (fluidity)	males	0.0 %	1.00
SHIRPA	gait (fluidity)	both	0.0 %	1.00
SHIRPA	genitalia morphology	females	0.0 %	1.00
SHIRPA	genitalia morphology	males	0.0 %	1.0
SHIRPA	genitalia morphology	both	0.0 %	1.00
SHIRPA	genitalia presence	females	0.0 %	1.0
SHIRPA	genitalia presence	males	0.0 %	1.0
SHIRPA	genitalia presence	both	0.0 %	1.0
SHIRPA	genitalia size	females	0.0 %	1.0
SHIRPA	genitalia size	males	0.0 %	1.0
SHIRPA	genitalia size	both	0.0 %	1.0
SHIRPA	head bobbing	females	0.0 %	1.0
SHIRPA	head bobbing	males	0.0 %	1.0
SHIRPA	head bobbing	both	0.0 %	1.0
SHIRPA	head morphology	females	0.0 %	1.0
SHIRPA	head morphology	males	0.0 %	1.00
SHIRPA	head morphology	both	0.0 %	1.0
SHIRPA	head size	females	0.0 %	1.0
SHIRPA	head size	males	0.0 %	1.0
SHIRPA	head size	both	0.0 %	1.00
SHIRPA	hindlimb digit number	females	1.0 %	1.00
SHIRPA	hindlimb digit number	males	0.0 %	1.0
SHIRPA	hindlimb digit number	both	0.0 %	1.00
SHIRPA	hindlimb digit position	females	0.0 %	1.0
SHIRPA	hindlimb digit position	males	0.0 %	1.0
SHIRPA	hindlimb digit position	both	0.0 %	1.0
SHIRPA	hindlimb digit shape	females	0.0 %	1.0
SHIRPA	hindlimb digit shape	males	0.0 %	1.0
SHIRPA	hindlimb digit shape	both	0.0 %	1.0
SHIRPA	hindlimb digit size	females	0.0 %	1.00
SHIRPA	hindlimb digit size	males	0.0 %	1.0
SHIRPA	hindlimb digit size	both	0.0 %	1.00
SHIRPA	hindlimb nail length	females	0.0 %	1.0
SHIRPA	hindlimb nail length	males	0.0 %	1.0
SHIRPA	hindlimb nail length	both	0.0 %	1.00
SHIRPA	hindlimb nail number	females	0.0 %	1.0
SHIRPA	hindlimb nail number	males	1.0 %	1.0
SHIRPA	hindlimb nail number	both	0.0 %	1.00
SHIRPA	hindlimb nail position	females	0.0 %	1.0
SHIRPA	hindlimb nail position	males	0.0 %	1.0
SHIRPA	hindlimb nail position	both	0.0 %	1.0
SHIRPA	hindlimb nail shape	females	0.0 %	1.0
SHIRPA	hindlimb nail shape	males	0.0 %	1.0
SHIRPA	hindlimb nail shape	both	0.0 %	1.0
SHIRPA	hindlimbs footpads	females	0.0 %	1.0
SHIRPA	hindlimbs footpads	males	0.0 %	1.0
SHIRPA	hindlimbs footpads	both	0.0 %	1.0
SHIRPA	hindlimbs position	females	0.0 %	1.0
SHIRPA	hindlimbs position	males	0.0 %	1.0
SHIRPA	hindlimbs position	both	0.0 %	1.0
SHIRPA	hindlimbs shape	females	0.0 %	1.0
SHIRPA	hindlimbs shape	males	0.0 %	1.0
SHIRPA	hindlimbs shape	both	0.0 %	1.0
SHIRPA	hindlimbs size	females	0.0 %	1.0
SHIRPA	hindlimbs size	males	0.0 %	1.0
SHIRPA	hindlimbs size	both	0.0 %	1.0
SHIRPA	hindpaw position	females	0.0 %	1.0
SHIRPA	hindpaw position	males	0.0 %	1.0
SHIRPA	hindpaw position	both	0.0 %	1.0
SHIRPA	hindpaw shape	females	0.0 %	1.0
SHIRPA	hindpaw shape	males	0.0 %	1.0
SHIRPA	hindpaw shape	both	0.0 %	1.0
SHIRPA	hindpaw size	females	0.0 %	1.0
SHIRPA	hindpaw size	males	0.0 %	1.0
SHIRPA	hindpaw size	both	0.0 %	1.0
SHIRPA	limb grasp	females	9.0 %	1.00
SHIRPA	limb grasp	males	6.0 %	1.0
SHIRPA	limb grasp	both	7.0 %	0.624
SHIRPA	lower lip morphology	females	0.0 %	1.0
SHIRPA	lower lip morphology	males	0.0 %	1.0
SHIRPA	lower lip morphology	both	0.0 %	1.0
SHIRPA	lower teeth appearance	females	0.0 %	1.0
SHIRPA	lower teeth appearance	males	0.0 %	1.00
SHIRPA	lower teeth appearance	both	0.0 %	1.00
SHIRPA	mouth morphology	females	0.0 %	1.0
SHIRPA	mouth morphology	males	0.0 %	1.00
SHIRPA	mouth morphology	both	0.0 %	1.00
SHIRPA	salivation	females	0.0 %	1.0
SHIRPA	salivation	males	0.0 %	1.0
SHIRPA	salivation	both	0.0 %	1.0
SHIRPA	skin color back paws	females	0.0 %	1.0
SHIRPA	skin color back paws	males	0.0 %	1.0
SHIRPA	skin color back paws	both	0.0 %	1.0
SHIRPA	skin color ear	females	0.0 %	1.0
SHIRPA	skin color ear	males	0.0 %	1.0
SHIRPA	skin color ear	both	0.0 %	1.0
SHIRPA	skin color front paws	females	0.0 %	1.0
SHIRPA	skin color front paws	males	0.0 %	1.0
SHIRPA	skin color front paws	both	0.0 %	1.0
SHIRPA	skin color snout	females	0.0 %	1.0
SHIRPA	skin color snout	males	0.0 %	1.0
SHIRPA	skin color snout	both	0.0 %	1.0
SHIRPA	skin color tail	females	0.0 %	1.0
SHIRPA	skin color tail	males	0.0 %	1.0
SHIRPA	skin color tail	both	0.0 %	1.0
SHIRPA	skin color whole body	females	0.0 %	1.0
SHIRPA	skin color whole body	males	0.0 %	1.0
SHIRPA	skin color whole body	both	0.0 %	1.0
SHIRPA	skin texture back paw	females	0.0 %	1.0
SHIRPA	skin texture back paw	males	0.0 %	1.0
SHIRPA	skin texture back paw	both	0.0 %	1.0
SHIRPA	skin texture ear	females	0.0 %	1.0
SHIRPA	skin texture ear	males	0.0 %	1.0
SHIRPA	skin texture ear	both	0.0 %	1.0
SHIRPA	skin texture front paws	females	0.0 %	1.0
SHIRPA	skin texture front paws	males	0.0 %	1.0
SHIRPA	skin texture front paws	both	0.0 %	1.0
SHIRPA	skin texture snout	females	0.0 %	1.0
SHIRPA	skin texture snout	males	0.0 %	1.0
SHIRPA	skin texture snout	both	0.0 %	1.0
SHIRPA	skin texture tail	females	0.0 %	1.0
SHIRPA	skin texture tail	males	0.0 %	1.0
SHIRPA	skin texture tail	both	0.0 %	1.0
SHIRPA	skin texture whole body	females	0.0 %	1.0
SHIRPA	skin texture whole body	males	0.0 %	1.00
SHIRPA	skin texture whole body	both	0.0 %	1.00
SHIRPA	snout size	females	0.0 %	1.0
SHIRPA	snout size	males	1.0 %	1.0
SHIRPA	snout size	both	0.0 %	1.0
SHIRPA	startle response	females	0.0 %	1.00
SHIRPA	startle response	males	0.0 %	1.00
SHIRPA	startle response	both	0.0 %	1.00
SHIRPA	tail curvature	females	0.0 %	1.00
SHIRPA	tail curvature	males	0.0 %	1.0
SHIRPA	tail curvature	both	0.0 %	1.0
SHIRPA	tail elevation	females	1.0 %	1.00
SHIRPA	tail elevation	males	2.0 %	1.0
SHIRPA	tail elevation	both	1.0 %	1.0
SHIRPA	tail length	females	0.0 %	1.0
SHIRPA	tail length	males	0.0 %	1.0
SHIRPA	tail length	both	0.0 %	1.00
SHIRPA	tail morphology	females	0.0 %	1.00
SHIRPA	tail morphology	males	0.0 %	1.0
SHIRPA	tail morphology	both	0.0 %	1.00
SHIRPA	tail presence	females	0.0 %	1.0
SHIRPA	tail presence	males	0.0 %	1.0
SHIRPA	tail presence	both	0.0 %	1.0
SHIRPA	tail shape	females	0.0 %	1.0
SHIRPA	tail shape	males	0.0 %	1.0
SHIRPA	tail shape	both	0.0 %	1.00
SHIRPA	tail thickness	females	0.0 %	1.0
SHIRPA	tail thickness	males	0.0 %	1.0
SHIRPA	tail thickness	both	0.0 %	1.0
SHIRPA	teeth presence	females	0.0 %	1.0
SHIRPA	teeth presence	males	0.0 %	1.00
SHIRPA	teeth presence	both	0.0 %	1.00
SHIRPA	transfer arousal	females	24.0 %	0.00359
SHIRPA	transfer arousal	males	24.0 %	0.00396
SHIRPA	transfer arousal	both	24.0 %	0.0000418
SHIRPA	tremor	females	0.0 %	1.0
SHIRPA	tremor	males	0.0 %	1.0
SHIRPA	tremor	both	0.0 %	1.00
SHIRPA	trunk curl	females	0.0 %	1.00
SHIRPA	trunk curl	males	0.0 %	1.0
SHIRPA	trunk curl	both	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	females	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	males	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	both	0.0 %	1.00
SHIRPA	upper lip morphology	females	0.0 %	1.0
SHIRPA	upper lip morphology	males	0.0 %	1.0
SHIRPA	upper lip morphology	both	0.0 %	1.0
SHIRPA	upper teeth appearance	females	0.0 %	1.0
SHIRPA	upper teeth appearance	males	0.0 %	1.0
SHIRPA	upper teeth appearance	both	0.0 %	1.00
SHIRPA	vibrissae appearance	females	2.0 %	1.0
SHIRPA	vibrissae appearance	males	1.0 %	1.0
SHIRPA	vibrissae appearance	both	1.0 %	1.0
SHIRPA	vibrissae presence	females	2.0 %	1.00
SHIRPA	vibrissae presence	males	1.0 %	1.0
SHIRPA	vibrissae presence	both	2.0 %	1.0
SHIRPA	vocalization	females	2.0 %	1.00
SHIRPA	vocalization	males	2.0 %	1.00
SHIRPA	vocalization	both	2.0 %	1.0

GENOTYPE CORRELATION PLOT

Correlate Gm17215^{em2(n-TAagc16)J} -/- with genotype: