MPD: JaxKOMP-EAP genotype: Ccdc85b<sup>em1(IMPC)J</sup>/Mmjax -/-

JaxKOMP-EAP effect sizes: Ccdc85b^em1(IMPC)J/Mmjax -/- Gene Ccdc85b

MULTIPLE (NUMERIC) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

Procedure	JaxKOMP-EAP Trait	Trait Effect	Trait Effect SE	Trait Effect RankZ	Adjusted p-value	Unadjusted p-value
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 6 kHz pip	-2.3774	3.4618	-0.91361	0.827	0.500
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 12 kHz pip	-0.72231	5.2100	-0.14719	0.964	0.891
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 18 kHz pip	1.0612	2.1672	0.067510	0.871	0.629
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 24 kHz pip	0.17185	3.4617	-0.090904	0.987	0.961
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 30 kHz pip	-0.13123	2.5402	-0.056106	0.985	0.959
body composition	body length	0.029322	0.038056	0.62738	0.723	0.446
body composition	body weight (at time of DXA)	-0.85532	0.60375	-0.53083	0.364	0.164
body composition	bone area, whole body scan, head excluded	-0.15567	0.12423	-0.43823	0.484	0.218
body composition	bone mineral content of whole body scan, head excluded	-0.0089653	0.010204	-0.37007	0.662	0.385
body composition	bone mineral content to body weight ratio	-0.00024573	0.00038775	-0.14247	0.750	0.530
body composition	bone mineral density of whole body scan, head excluded	0.00029033	0.00062789	0.33034	0.831	0.646
body composition	fat tissue mass of whole body scan, head excluded	-0.13275	0.35430	-0.23001	0.858	0.710
body composition	fat tissue mass to body weight ratio	-0.0088916	0.011498	-0.35986	0.669	0.444
body composition	lean tissue mass of whole body scan, head excluded	0.15057	0.33882	0.15489	0.863	0.659
body composition	lean tissue mass to body weight ratio	0.0053036	0.011279	0.23786	0.826	0.641
body composition	percent fat, whole body scan, head excluded	-0.83445	1.1315	-0.37007	0.689	0.465
body composition	ratio of soft-tissue attenuation coefficients	0.00094313	0.0012580	0.37092	0.684	0.458
body composition	tissue area	-0.49834	0.19656	-1.3410	0.126	0.0154
body composition	total tissue mass, whole body scan, head excluded	0.17614	0.18433	0.18120	0.598	0.345
clinical blood chemistry	alanine transaminase (plasma ALT)	-5.1265	6.3037	-0.49648	0.751	0.424
clinical blood chemistry	albumin (plasma Alb)	0.73177	0.53168	1.0679	0.503	0.181
clinical blood chemistry	alkaline phosphatase (plasma ALP)	3.2489	2.6636	0.043231	0.481	0.234
clinical blood chemistry	aspartate transaminase (plasma AST)	-41.680	18.657	-1.6308	0.247	0.0347
clinical blood chemistry	aspartate transaminase to alanine transaminase ratio (plasma AST:ALT)	-0.65278	0.32897	-1.7418	0.391	0.0583
clinical blood chemistry	blood urea nitrogen (BUN)	-0.62038	1.4091	-0.27055	0.838	0.664
clinical blood chemistry	calcium (plasma Ca)	-0.096157	0.061386	-0.32631	0.334	0.130
clinical blood chemistry	creatinine (plasma)	0.016489	0.024229	0.51295	0.725	0.502
clinical blood chemistry	glucose (plasma GLU, no fast)	4.3827	10.207	0.46070	0.815	0.671
clinical blood chemistry	HDL cholesterol (plasma HDL)	6.8126	3.0208	1.2283	0.201	0.0331
clinical blood chemistry	HDL cholesterol to total cholesterol ratio	0.018728	0.013141	0.91100	0.495	0.166
clinical blood chemistry	phosphorus (plasma phosphate)	-0.80498	0.27663	-1.2976	0.0813	0.00768
clinical blood chemistry	total bilirubin (plasma TBIL)	-0.015952	0.0087250	-1.1173	0.335	0.0795
clinical blood chemistry	total cholesterol (plasma CHOL, no fast)	7.6750	3.6039	1.0278	0.219	0.0432
clinical blood chemistry	total protein (plasma TP)	1.1233	0.86305	0.83190	0.488	0.205
clinical blood chemistry	triglyceride (plasma TG, no fast)	-12.098	9.5842	-0.45440	0.516	0.219
EKG	duration of PQ interval	-1.3278	0.82733	-1.1801	0.688	0.121
EKG	duration of PR interval	-1.2711	0.87652	-1.0955	0.712	0.159
EKG	duration of QRS interval	0.30921	0.40287	0.74980	0.911	0.450
EKG	duration of QT interval	-0.17543	0.98114	-0.014105	0.982	0.859
EKG	duration of QTC interval, calculated by dividing QT interval by square root of preceding RR interval	0.55592	0.89744	0.67196	0.925	0.541
EKG	duration of RR interval	-2.8116	1.7812	-1.2048	0.533	0.127
EKG	duration of ST interval	-0.30982	0.84406	-0.10092	0.949	0.717
EKG	heart rate coefficient of variation (signal intensity)	-0.95777	1.3720	-0.70258	0.878	0.491
EKG	heart rate variability, mean of differences between sequential beats; beats per min	-5.7053	9.6859	-0.58361	0.924	0.561
EKG	heart rate, beats per min	22.839	14.329	1.1716	0.496	0.123
EKG	mean R amplitude, mean amplitude of signal measured from isoelectric line to peak of QRS	-0.022961	0.077512	-0.30409	0.924	0.769
EKG	mean SR amplitude, mean amplitude of signal measured from signal minimum line to peak of QRS	0.012769	0.10036	-0.0030249	0.961	0.900
EKG	number of signals	-4.6705	4.5445	-0.93054	0.804	0.314
EKG	proportion of number pairs of successive beat-to-beat intervals that exceed 50 ms	-5.3095	6.2304	-0.94917	0.848	0.402
EKG	QT dispersion, measured as inter-lead variability of QT intervals	-3.9894	4.3665	-1.1253	0.917	0.369
EKG	QTc dispersion, calculated as rate-corrected QT dispersion	-4.4178	4.8009	-1.1484	0.911	0.366
EKG	root mean square of successive differences of neighboring RR intervals	-0.70158	2.1457	-0.25668	0.947	0.746
glucose tolerance test	amount glucose injected	-4.0800	4.3020	-0.80991	0.714	0.355
glucose tolerance test	plasma glucose, 0min	2.9500	4.5564	0.075573	0.725	0.525
glucose tolerance test	plasma glucose, 15min	6.3210	24.219	0.29382	0.934	0.797
glucose tolerance test	plasma glucose, 30min	-34.350	15.045	-0.94002	0.208	0.0335
glucose tolerance test	plasma glucose, 60min	-18.412	9.7994	-0.67708	0.322	0.0749
glucose tolerance test	plasma glucose, 120min	-2.2250	7.4398	-0.28953	0.917	0.768
grip strength	body weight (at time of grip strength test)	0.17753	0.43082	0.37410	0.819	0.684
grip strength	forelimb and hindlimb grip strength (mean of trials), average	-9.6739	7.5674	-0.44565	0.413	0.212
grip strength	forelimb and hindlimb grip strength (mean of trials), average normalized to bw	-0.57986	0.32163	-0.66450	0.235	0.0830
grip strength	forelimb and hindlimb grip strength by trial, trial1	-10.099	10.787	-0.46013	0.655	0.358
grip strength	forelimb and hindlimb grip strength by trial, trial2	-0.31875	11.506	0.20622	0.990	0.978
grip strength	forelimb and hindlimb grip strength by trial, trial3	-18.578	10.293	-0.95513	0.288	0.0827
grip strength	forelimb grip strength (mean of trials), average	8.5479	6.5250	1.3528	0.453	0.201
grip strength	forelimb grip strength (mean of trials), average normalized to bw	0.27785	0.26176	0.96665	0.575	0.298
grip strength	forelimb grip strength by trial, trial1	2.7375	9.8151	0.56790	0.918	0.782
grip strength	forelimb grip strength by trial, trial2	6.1188	7.6264	0.91466	0.744	0.429
grip strength	forelimb grip strength by trial, trial3	16.788	9.1306	1.8381	0.328	0.0770
heart weight	heart weight, normalized to body weight	0.012908	0.097893	-0.40614	0.949	0.896
heart weight	heart weight, weight	-1.9598	4.1423	-0.61910	0.790	0.640
hematology	basophil differential (percent of total WBC)	0.063462	0.053911	0.92728	0.690	0.251
hematology	calculated hemoglobin (cHGB)	-0.070192	0.18709	-0.49982	0.864	0.711
hematology	eosinophil differential (percent of total WBC)	-0.36693	0.26367	-0.91524	0.567	0.177
hematology	hematocrit (HCT)	0.36652	0.58430	0.020503	0.745	0.536
hematology	hemoglobin concentration distribution width (HDW)	-0.077320	0.043608	-1.8938	0.355	0.0895
hematology	large unstained cells (percent of total WBC)	0.042240	0.067206	0.28252	0.809	0.536
hematology	lymphocyte differential (percent of total WBC)	1.2041	0.92337	0.43273	0.457	0.205
hematology	mean corpuscular hemoglobin (CHr)	0.034688	0.086959	0.31991	0.848	0.693
hematology	mean platelet volume (MPV)	-0.080116	0.11555	-0.72131	0.712	0.495
hematology	mean RBC corpuscular hemoglobin (MCH)	-0.47316	0.32073	-1.1266	0.497	0.153
hematology	mean RBC corpuscular hemoglobin concentration (MCHC)	-1.2137	0.91470	-1.3637	0.560	0.197
hematology	mean RBC corpuscular volume (MCV)	0.68625	0.39562	1.1834	0.254	0.0962
hematology	measured hemoglobin (mHGB)	-0.37692	0.47543	-1.0178	0.696	0.436
hematology	monocyte differential (percent of total WBC)	-0.18280	0.15456	-0.40883	0.611	0.249
hematology	neutrophil differential (percent of total WBC)	-0.73622	0.77705	-0.33847	0.586	0.353
hematology	platelet count (PLT; units per volume x 10³)	52.797	36.648	0.74572	0.546	0.163
hematology	RBC corpuscular distribution width (RDW)	-0.087836	0.16409	-0.32279	0.785	0.597
hematology	RBC corpuscular hemoglobin concentration mean (CHCM)	-0.51999	0.18727	-1.3306	0.0736	0.0105
hematology	red blood cell count (RBC; per volume x 10⁶)	-0.10607	0.16097	-0.77042	0.741	0.516
hematology	reticulocyte count (Retic; units per volume x 10⁹)	-16.522	41.635	-0.62905	0.906	0.695
hematology	reticulocyte differential (percent of total RBC)	-0.17149	0.52626	-0.53732	0.904	0.747
hematology	white blood cell count (WBC; units per volume x 10³)	-0.28910	0.59558	-0.021870	0.784	0.632
holeboard	number of hole pokes by individual hole number, 20 min test, 1	-0.034049	0.78500	0.019413	0.990	0.966
holeboard	number of hole pokes by individual hole number, 20 min test, 2	-0.16959	0.73386	-0.13801	0.969	0.818
holeboard	number of hole pokes by individual hole number, 20 min test, 3	-0.22547	0.46899	-0.29894	0.923	0.633
holeboard	number of hole pokes by individual hole number, 20 min test, 4	0.073404	0.80772	0.16020	0.984	0.928
holeboard	number of hole pokes by individual hole number, 20 min test, 5	0.12640	0.43089	0.32909	0.953	0.770
holeboard	number of hole pokes by individual hole number, 20 min test, 6	-0.058302	0.26191	-0.10138	0.970	0.825
holeboard	number of hole pokes by individual hole number, 20 min test, 7	0.33180	0.28611	0.84790	0.827	0.252
holeboard	number of hole pokes by individual hole number, 20 min test, 8	-0.24023	0.37043	-0.28134	0.881	0.520
holeboard	number of hole pokes by individual hole number, 20 min test, 9	0.35572	0.39253	0.74847	0.822	0.369
holeboard	number of hole pokes by individual hole number, 20 min test, 10	0.24207	0.31473	0.67555	0.878	0.446
holeboard	number of hole pokes by individual hole number, 20 min test, 11	0.14180	0.33023	0.38605	0.928	0.670
holeboard	number of hole pokes by individual hole number, 20 min test, 12	0.39509	0.45938	0.72075	0.801	0.394
holeboard	number of hole pokes by individual hole number, 20 min test, 13	-0.17699	0.74240	-0.091215	0.949	0.813
holeboard	number of hole pokes by individual hole number, 20 min test, 14	0.11599	0.47536	0.27326	0.953	0.808
holeboard	number of hole pokes by individual hole number, 20 min test, 15	0.19403	0.46090	0.36379	0.903	0.676
holeboard	number of hole pokes by individual hole number, 20 min test, 16	1.2075	0.84531	1.0595	0.584	0.159
holeboard	total number of hole pokes, 20 min test	2.6259	4.0230	0.43690	0.747	0.517
light / dark	fecal boli count, 20 min test	2.0345	0.70404	2.0171	0.176	0.00573
light / dark	latency to enter dark zone, 20 min test	51.275	45.168	0.80332	0.676	0.262
light / dark	number of transitions between light and dark zones, 20 min test	-10.134	8.9878	-0.93553	0.594	0.265
light / dark	percentage of total time in dark zone, 20 min test	6.8196	3.1048	1.3954	0.288	0.0329
light / dark	percentage of total time in light zone, 20 min test	-6.8196	3.1048	-1.3990	0.284	0.0329
light / dark	time mobile in dark zone, 20 min test	-5.1535	13.820	-0.45309	0.883	0.711
light / dark	time mobile in light zone, 20 min test	-8.9013	9.6840	-0.88240	0.628	0.363
light / dark	time spent in dark zone, 20 min test	23.021	49.397	0.54813	0.889	0.643
light / dark	time spent in light zone, 20 min test	-23.021	49.397	-0.54813	0.889	0.643
open field	average speed in center of arena, 20 min test	-0.44842	0.35272	-0.91141	0.553	0.210
open field	average speed in periphery of arena, 20 min test	-0.034462	0.13806	-0.66567	0.896	0.804
open field	distance traveled habituation ratio, 20 min test	2.2518	7.6297	0.23095	0.905	0.769
open field	distance traveled in center of arena, 20 min test	43.864	94.374	-0.10964	0.801	0.644
open field	distance traveled in periphery of arena, 20 min test	-85.849	124.14	-0.76451	0.715	0.492
open field	distance traveled slope, 20 min test	2.6749	7.2823	0.31176	0.895	0.715
open field	distance traveled, 20 min test, 1st 5min	-15.749	68.199	-0.47887	0.920	0.818
open field	distance traveled, 20 min test, 2nd 5min	-31.711	52.034	-0.86754	0.754	0.545
open field	distance traveled, 20 min test, 3rd 5min	-7.8625	47.747	-0.53692	0.947	0.870
open field	distance traveled, 20 min test, 4th 5min	-5.5080	47.219	-0.53382	0.966	0.908
open field	number of clockwise revolution episodes, 20 min test	1.2125	1.2478	0.30278	0.694	0.336
open field	number of counter-clockwise revolution episodes, 20 min test	-0.35381	0.89883	-0.60972	0.850	0.696
open field	number of fecal boli, 20 min test	0.72500	0.73064	0.76867	0.645	0.326
open field	number of rears in 5 min bins, 20 min test, 1st 5min	0.88236	1.9298	0.021495	0.829	0.649
open field	number of rears in 5 min bins, 20 min test, 2nd 5min	-2.4375	2.0667	-0.95711	0.538	0.244
open field	number of rears in 5 min bins, 20 min test, 3rd 5min	-1.8875	2.3403	-0.72552	0.686	0.424
open field	number of rears in 5 min bins, 20 min test, 4th 5min	-1.5875	2.1092	-0.68421	0.703	0.455
open field	percentage of total time in center of arena, 20 min test	1.1247	2.5822	0.061126	0.871	0.665
open field	percentage of total time in center of arena, slope, 20 min test	0.41978	1.3252	0.35291	0.946	0.753
open field	percentage of total time in center, habituation ratio, 20 min test	0.53056	1.2889	0.40484	0.907	0.682
open field	percentage of total time in corners of arena, 20 min test	1.8755	4.6527	0.64404	0.875	0.689
open field	percentage of total time in corners, habituation ratio, 20 min test	0.61396	1.6026	-0.00067130	0.946	0.703
open field	percentage of total time in corners, slope, 20 min test	0.79895	1.6004	0.092098	0.917	0.620
open field	permanence time in center of arena, 20 min test	13.493	30.989	0.063817	0.872	0.665
open field	permanence time in corners of arena, 20 min test	22.511	55.833	0.64569	0.876	0.689
open field	permanence time in periphery of arena, 20 min test	-13.486	30.994	-0.062471	0.872	0.665
open field	total distance traveled, 20 min test	-50.965	179.88	-0.64404	0.887	0.778
open field	total number of rears, 20 min test	-5.1750	6.8855	-0.69102	0.692	0.456
open field	whole arena average speed, 20 min test	-0.042355	0.14989	-0.64404	0.889	0.779
open field	whole arena resting time, 20 min test	0.044999	18.750	0.56662	0.999	0.998
open field	whole arena time spent mobile, 20 min test	-0.059999	18.726	-0.53227	0.998	0.997
open field	whole arena time spent vertical, 20 min test	-12.530	7.4386	-1.0716	0.355	0.0983
SHIRPA	locomotor activity (number of squares in the arena the mouse moves into with all four paws in first 30 s of test)	1.5563	1.6130	0.85259	0.644	0.343
startle / PPI	average baseline movement during background noise	0.42933	1.2689	0.37050	0.951	0.738
startle / PPI	average of each corrected maximum percent pre-pulse inhibition value	0.078892	0.062499	0.62815	0.580	0.217
startle / PPI	average of each corrected percent pre-pulse inhibition value	0.091655	0.060861	0.81474	0.484	0.143
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	10.198	6.2068	1.1575	0.843	0.112
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	10.429	7.9767	1.0112	0.571	0.202
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	9.4016	7.1910	0.85124	0.492	0.202
startle / PPI	average startle response to full pulse (120 dB)	-15.641	36.165	-0.13562	0.850	0.669
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-35.128	46.237	-0.49837	0.679	0.454
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-45.819	45.363	-0.71597	0.536	0.321
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-40.437	37.322	-0.75453	0.512	0.288
startle / PPI	average startle response to pre-pulse, 74dB sound pressure level	-0.76366	1.4878	-0.50791	0.915	0.612
startle / PPI	average startle response to pre-pulse, 78dB sound pressure level	-1.5923	1.8548	-1.0890	0.857	0.398
startle / PPI	average startle response to pre-pulse, 82dB sound pressure level	-2.9456	2.6628	-1.5852	0.697	0.278
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	0.10689	0.066338	1.0493	0.794	0.119
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	0.10701	0.083237	0.82258	0.556	0.209
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	0.090417	0.080354	0.53796	0.533	0.270
startle / PPI	corrected average startle response to full pulse (120 dB) minus average baseline movement during background noise	-15.345	36.403	-0.13704	0.852	0.677
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 74dB sound pressure level	-33.510	46.455	-0.47628	0.694	0.477
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 78dB sound pressure level	-43.124	45.364	-0.65918	0.563	0.350
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 82dB sound pressure level	-38.022	37.542	-0.68730	0.533	0.320
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	0.11278	0.063668	0.99271	0.758	0.0878
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	0.074548	0.082539	0.50265	0.688	0.374
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	0.095164	0.082367	0.52665	0.524	0.258
startle / PPI	corrected maximum startle response to full pulse (120 dB) minus maximum baseline movement during background noise	-36.188	128.39	-0.028727	0.913	0.780
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 74dB sound pressure level	-149.51	171.40	-0.59103	0.614	0.391
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 78dB sound pressure level	-117.91	162.37	-0.45753	0.664	0.474
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 82dB sound pressure level	-126.76	138.03	-0.60107	0.578	0.366
startle / PPI	maximum baseline movement during background noise	0.17238	3.2905	0.17961	0.989	0.959
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	10.808	6.0481	1.1096	0.781	0.0852
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	7.3171	7.9608	0.57112	0.706	0.366
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	9.6083	7.6370	0.76575	0.504	0.219
startle / PPI	maximum startle response to full pulse (120 dB)	-37.242	127.56	-0.034335	0.906	0.772
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-151.56	171.01	-0.60780	0.604	0.383
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-124.08	161.92	-0.50155	0.653	0.450
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-133.25	137.12	-0.66791	0.555	0.339
startle / PPI	maximum startle response to pre-pulse, 74dB sound pressure level	-3.2838	3.2723	-0.89431	0.775	0.324
startle / PPI	maximum startle response to pre-pulse, 78dB sound pressure level	-5.3829	4.2930	-1.3906	0.715	0.220
startle / PPI	maximum startle response to pre-pulse, 82dB sound pressure level	-7.9244	6.7421	-1.6866	0.633	0.250

MULTIPLE (CATEGORICAL) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

Procedure	JaxKOMP-EAP Trait	Trait Effect	P-value
eye morphology	anterior chamber depth	1.0 %	1.0
eye morphology	bulging eye	1.0 %	1.00
eye morphology	cornea	6.0 %	0.248
eye morphology	cornea opacity	4.0 %	0.428
eye morphology	cornea vascularization	6.0 %	0.234
eye morphology	corneal deposits	1.0 %	1.00
eye morphology	corneal mineralization	1.0 %	1.00
eye morphology	corneal scleralization	2.0 %	1.00
eye morphology	corneal ulcer	1.0 %	1.00
eye morphology	eye closure	1.0 %	1.0
eye morphology	eye hemorrhage or blood presence	1.0 %	1.00
eye morphology	eyelid morphology	1.0 %	1.0
eye morphology	eyes (present, absent)	0.0 %	1.0
eye morphology	fusion between cornea and lens	3.0 %	1.00
eye morphology	iris pigmentation	2.0 %	1.00
eye morphology	iris transillumination	1.0 %	1.00
eye morphology	irispupil	5.0 %	0.435
eye morphology	lacrimation	3.0 %	1.0
eye morphology	lens	9.0 %	1.0
eye morphology	lens opacity	18.0 %	0.0135
eye morphology	narrow eye opening	1.0 %	1.0
eye morphology	optic disc	3.0 %	1.00
eye morphology	persistence of hyaloid vascular system	11.0 %	0.152
eye morphology	pupil dilation	2.0 %	1.0
eye morphology	pupil light response	2.0 %	1.00
eye morphology	pupil position	4.0 %	1.00
eye morphology	pupil shape	3.0 %	1.00
eye morphology	retina	9.0 %	0.503
eye morphology	retinal blood vessels	3.0 %	1.0
eye morphology	retinal blood vessels pattern	6.0 %	0.0675
eye morphology	retinal blood vessels structure	3.0 %	1.00
eye morphology	retinal pigmentation	13.0 %	1.0
eye morphology	retinal structure	3.0 %	1.00
eye morphology	synechia	3.0 %	1.00
eye morphology	vitreous	3.0 %	1.00
SHIRPA	activity body position	1.0 %	1.00
SHIRPA	aggression	1.0 %	1.0
SHIRPA	body length	0.0 %	1.00
SHIRPA	body position	0.0 %	1.00
SHIRPA	body thickness	0.0 %	1.0
SHIRPA	coat color abdomen	4.0 %	1.0
SHIRPA	coat color back	0.0 %	1.00
SHIRPA	coat color head	0.0 %	1.0
SHIRPA	coat color pattern abdomen	1.0 %	1.0
SHIRPA	coat color pattern back	0.0 %	1.0
SHIRPA	coat color pattern head	0.0 %	1.00
SHIRPA	coat hair abdomen texture appearance	2.0 %	1.0
SHIRPA	coat hair back texture appearance	0.0 %	1.0
SHIRPA	coat hair distribution abdomen	1.0 %	1.0
SHIRPA	coat hair distribution back	0.0 %	1.0
SHIRPA	coat hair distribution head	1.0 %	1.00
SHIRPA	coat hair head texture appearance	0.0 %	1.0
SHIRPA	contact righting	5.0 %	1.0
SHIRPA	ear morphology	0.0 %	1.0
SHIRPA	fat distribution	0.0 %	1.0
SHIRPA	forelimb digit number	0.0 %	1.0
SHIRPA	forelimb digit position	0.0 %	1.0
SHIRPA	forelimb digit shape	0.0 %	1.00
SHIRPA	forelimb digit size	0.0 %	1.00
SHIRPA	forelimb footpads	0.0 %	1.00
SHIRPA	forelimb nail length	0.0 %	1.0
SHIRPA	forelimb nail number	0.0 %	1.00
SHIRPA	forelimb nail position	0.0 %	1.0
SHIRPA	forelimb nail shape	0.0 %	1.0
SHIRPA	forelimbs position	0.0 %	1.0
SHIRPA	forelimbs shape	0.0 %	1.0
SHIRPA	forelimbs size	0.0 %	1.00
SHIRPA	forepaw position	0.0 %	1.0
SHIRPA	forepaw shape	0.0 %	1.0
SHIRPA	forepaw size	0.0 %	1.0
SHIRPA	gait (fluidity)	0.0 %	1.0
SHIRPA	genitalia morphology	0.0 %	1.0
SHIRPA	genitalia presence	0.0 %	1.00
SHIRPA	genitalia size	0.0 %	1.0
SHIRPA	head bobbing	0.0 %	1.00
SHIRPA	head morphology	0.0 %	1.00
SHIRPA	head size	0.0 %	1.0
SHIRPA	hindlimb digit number	0.0 %	1.0
SHIRPA	hindlimb digit position	0.0 %	1.00
SHIRPA	hindlimb digit shape	0.0 %	1.0
SHIRPA	hindlimb digit size	0.0 %	1.0
SHIRPA	hindlimb nail length	0.0 %	1.0
SHIRPA	hindlimb nail number	0.0 %	1.0
SHIRPA	hindlimb nail position	0.0 %	1.0
SHIRPA	hindlimb nail shape	0.0 %	1.0
SHIRPA	hindlimbs footpads	0.0 %	1.00
SHIRPA	hindlimbs position	0.0 %	1.0
SHIRPA	hindlimbs shape	0.0 %	1.0
SHIRPA	hindlimbs size	0.0 %	1.0
SHIRPA	hindpaw position	0.0 %	1.00
SHIRPA	hindpaw shape	0.0 %	1.00
SHIRPA	hindpaw size	0.0 %	1.00
SHIRPA	limb grasp	1.0 %	0.596
SHIRPA	lower lip morphology	0.0 %	1.00
SHIRPA	lower teeth appearance	0.0 %	1.0
SHIRPA	mouth morphology	0.0 %	1.0
SHIRPA	salivation	0.0 %	1.0
SHIRPA	skin color back paws	0.0 %	1.0
SHIRPA	skin color ear	0.0 %	1.0
SHIRPA	skin color front paws	0.0 %	1.0
SHIRPA	skin color snout	0.0 %	1.0
SHIRPA	skin color tail	0.0 %	1.00
SHIRPA	skin color whole body	0.0 %	1.00
SHIRPA	skin texture back paw	0.0 %	1.00
SHIRPA	skin texture ear	0.0 %	1.0
SHIRPA	skin texture front paws	0.0 %	1.0
SHIRPA	skin texture snout	0.0 %	1.0
SHIRPA	skin texture tail	0.0 %	1.0
SHIRPA	skin texture whole body	0.0 %	1.00
SHIRPA	snout size	0.0 %	1.0
SHIRPA	startle response	0.0 %	1.0
SHIRPA	tail curvature	0.0 %	1.0
SHIRPA	tail elevation	1.0 %	1.0
SHIRPA	tail length	0.0 %	1.0
SHIRPA	tail morphology	0.0 %	1.00
SHIRPA	tail presence	0.0 %	1.0
SHIRPA	tail shape	0.0 %	1.0
SHIRPA	tail thickness	0.0 %	1.0
SHIRPA	teeth presence	0.0 %	1.0
SHIRPA	transfer arousal	1.0 %	1.0
SHIRPA	tremor	0.0 %	1.0
SHIRPA	trunk curl	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	0.0 %	1.0
SHIRPA	upper lip morphology	0.0 %	1.0
SHIRPA	upper teeth appearance	0.0 %	1.0
SHIRPA	vibrissae appearance	1.0 %	1.0
SHIRPA	vibrissae presence	2.0 %	1.0
SHIRPA	vocalization	2.0 %	1.0

GENOTYPE CORRELATION PLOT

Correlate Ccdc85b^em1(IMPC)J/Mmjax -/- with genotype: