MPD: JaxKOMP-EAP genotype: Asmt<sup>em1(IMPC)J</sup>/Mmjax -/-

JaxKOMP-EAP effect sizes: Asmt^em1(IMPC)J/Mmjax -/- Gene Asmt

MULTIPLE (NUMERIC) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

Procedure	JaxKOMP-EAP Trait	Trait Effect	Trait Effect SE	Trait Effect RankZ	Adjusted p-value	Unadjusted p-value
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 6 kHz pip	-5.3901	6.1271	-1.5519	0.851	0.541
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 12 kHz pip	-7.3702	7.8380	-1.3591	0.846	0.520
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 18 kHz pip	-4.8864	2.3252	-1.1716	0.636	0.283
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 24 kHz pip	2.5000	4.6466	0.28018	0.883	0.686
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 30 kHz pip	-5.4545	3.2778	-0.85690	0.690	0.344
body composition	body length	-0.10089	0.050414	-0.92270	0.241	0.0545
body composition	body weight (at time of DXA)	0.95912	0.65629	0.88198	0.349	0.154
body composition	bone area, whole body scan, head excluded	-0.25711	0.12164	-0.83619	0.197	0.0430
body composition	bone mineral content of whole body scan, head excluded	-0.013382	0.012482	-0.59597	0.582	0.292
body composition	bone mineral content to body weight ratio	-0.000070263	0.00047908	0.053271	0.955	0.884
body composition	bone mineral density of whole body scan, head excluded	0.00014967	0.00072489	0.20008	0.935	0.838
body composition	fat tissue mass of whole body scan, head excluded	0.43984	0.45145	0.69520	0.595	0.337
body composition	fat tissue mass to body weight ratio	-0.00035327	0.016278	0.040969	0.996	0.983
body composition	lean tissue mass of whole body scan, head excluded	-0.31393	0.41326	-0.83619	0.732	0.453
body composition	lean tissue mass to body weight ratio	-0.0040463	0.013690	-0.28166	0.889	0.770
body composition	percent fat, whole body scan, head excluded	0.15805	1.5444	0.15213	0.965	0.919
body composition	ratio of soft-tissue attenuation coefficients	-0.00017809	0.0017159	-0.15662	0.968	0.918
body composition	tissue area	-0.072045	0.21675	-0.065651	0.911	0.742
body composition	total tissue mass, whole body scan, head excluded	0.032253	0.22149	-0.14523	0.949	0.885
clinical blood chemistry	alanine transaminase (plasma ALT)	8.4844	2.7801	0.65198	0.200	0.0122
clinical blood chemistry	albumin (plasma Alb)	-0.031250	0.61927	0.011407	0.989	0.961
clinical blood chemistry	alkaline phosphatase (plasma ALP)	3.4219	4.7536	0.071618	0.711	0.488
clinical blood chemistry	aspartate transaminase (plasma AST)	12.203	8.3922	0.52505	0.494	0.177
clinical blood chemistry	aspartate transaminase to alanine transaminase ratio (plasma AST:ALT)	-0.058641	0.17496	-0.18702	0.925	0.744
clinical blood chemistry	blood urea nitrogen (BUN)	-1.0781	1.7009	-0.48807	0.756	0.540
clinical blood chemistry	calcium (plasma Ca)	0.24043	0.12357	1.8398	0.256	0.0835
clinical blood chemistry	creatinine (plasma)	-0.025000	0.021548	-0.47144	0.524	0.273
clinical blood chemistry	glucose (plasma GLU, no fast)	-9.4531	12.149	-0.073623	0.655	0.455
clinical blood chemistry	HDL cholesterol (plasma HDL)	-0.40013	5.1581	-0.42866	0.982	0.940
clinical blood chemistry	HDL cholesterol to total cholesterol ratio	-0.033341	0.011971	-1.8711	0.181	0.0212
clinical blood chemistry	phosphorus (plasma phosphate)	1.4268	0.86142	1.8466	0.378	0.132
clinical blood chemistry	total bilirubin (plasma TBIL)	-0.0054688	0.010234	-0.42865	0.838	0.605
clinical blood chemistry	total cholesterol (plasma CHOL, no fast)	2.7443	7.4117	0.25217	0.898	0.720
clinical blood chemistry	total protein (plasma TP)	-0.56400	1.0778	-0.49159	0.803	0.613
clinical blood chemistry	triglyceride (plasma TG, no fast)	47.413	8.4491	1.9985	0.0211	0.000329
EKG	duration of PQ interval	0.56125	1.1668	0.73652	0.929	0.634
EKG	duration of PR interval	0.96000	1.0950	1.1330	0.877	0.388
EKG	duration of QRS interval	0.27625	0.28894	0.62717	0.885	0.347
EKG	duration of QT interval	0.31427	0.92571	0.45443	0.945	0.737
EKG	duration of QTC interval, calculated by dividing QT interval by square root of preceding RR interval	-0.42340	0.97364	-0.39271	0.946	0.667
EKG	duration of RR interval	1.6249	1.3904	1.0845	0.673	0.252
EKG	duration of ST interval	0.053001	0.87942	0.24836	0.986	0.952
EKG	heart rate coefficient of variation (signal intensity)	-1.2192	0.96243	-0.94304	0.841	0.215
EKG	heart rate variability, mean of differences between sequential beats; beats per min	-10.377	6.4251	-1.1965	0.832	0.117
EKG	heart rate, beats per min	-15.474	11.353	-1.2558	0.573	0.183
EKG	mean R amplitude, mean amplitude of signal measured from isoelectric line to peak of QRS	-0.0094611	0.10298	-0.21026	0.974	0.927
EKG	mean SR amplitude, mean amplitude of signal measured from signal minimum line to peak of QRS	0.048414	0.10889	0.17533	0.869	0.660
EKG	number of signals	4.1139	7.0801	0.77132	0.883	0.566
EKG	proportion of number pairs of successive beat-to-beat intervals that exceed 50 ms	-1.2109	5.1977	-0.16143	0.974	0.817
EKG	QT dispersion, measured as inter-lead variability of QT intervals	-4.0782	3.5760	-1.1562	0.881	0.263
EKG	QTc dispersion, calculated as rate-corrected QT dispersion	-5.2944	3.7986	-1.3556	0.856	0.174
EKG	root mean square of successive differences of neighboring RR intervals	-3.2556	1.9528	-1.5591	0.843	0.106
glucose tolerance test	amount glucose injected	-6.6765	7.8047	-1.4581	0.742	0.402
glucose tolerance test	plasma glucose, 0min	3.6750	6.4863	0.15575	0.762	0.577
glucose tolerance test	plasma glucose, 15min	41.045	17.448	1.2117	0.204	0.0285
glucose tolerance test	plasma glucose, 30min	21.567	15.016	0.76798	0.504	0.165
glucose tolerance test	plasma glucose, 60min	8.3320	17.320	0.46513	0.862	0.635
glucose tolerance test	plasma glucose, 120min	11.775	6.9467	0.68921	0.396	0.104
grip strength	body weight (at time of grip strength test)	0.96560	0.44825	1.0646	0.125	0.0403
grip strength	forelimb and hindlimb grip strength (mean of trials), average	24.314	6.8651	1.8962	0.0152	0.00147
grip strength	forelimb and hindlimb grip strength (mean of trials), average normalized to bw	0.75155	0.29738	1.2607	0.0843	0.0177
grip strength	forelimb and hindlimb grip strength by trial, trial1	19.406	9.5905	1.4793	0.238	0.0530
grip strength	forelimb and hindlimb grip strength by trial, trial2	24.257	9.5858	1.6995	0.111	0.0175
grip strength	forelimb and hindlimb grip strength by trial, trial3	22.373	8.9648	1.5824	0.121	0.0192
grip strength	forelimb grip strength (mean of trials), average	1.1119	4.2156	0.43285	0.914	0.794
grip strength	forelimb grip strength (mean of trials), average normalized to bw	0.016546	0.18857	0.28406	0.974	0.931
grip strength	forelimb grip strength by trial, trial1	1.6375	6.2830	0.45368	0.923	0.796
grip strength	forelimb grip strength by trial, trial2	-0.43003	6.1539	0.16191	0.981	0.945
grip strength	forelimb grip strength by trial, trial3	1.6653	7.0534	0.45046	0.928	0.815
heart weight	heart weight, normalized to body weight	-0.24977	0.087781	-1.3993	0.0640	0.0112
heart weight	heart weight, weight	-9.7785	3.4339	-1.6230	0.0724	0.0116
hematology	basophil differential (percent of total WBC)	-0.0024194	0.036599	-0.019220	0.993	0.948
hematology	calculated hemoglobin (cHGB)	0.14032	0.20529	0.15181	0.753	0.506
hematology	eosinophil differential (percent of total WBC)	-1.1642	0.67539	-2.2934	0.496	0.110
hematology	hematocrit (HCT)	0.90605	0.62934	0.66168	0.459	0.174
hematology	hemoglobin concentration distribution width (HDW)	-0.055363	0.032557	-1.3975	0.385	0.113
hematology	large unstained cells (percent of total WBC)	0.10605	0.087122	0.68269	0.591	0.245
hematology	lymphocyte differential (percent of total WBC)	8.2913	2.2095	2.3771	0.0449	0.00276
hematology	mean corpuscular hemoglobin (CHr)	0.021371	0.053089	0.22092	0.848	0.694
hematology	mean platelet volume (MPV)	-0.41371	0.23153	-1.8956	0.258	0.0973
hematology	mean RBC corpuscular hemoglobin (MCH)	0.15403	0.084566	0.57034	0.396	0.0916
hematology	mean RBC corpuscular hemoglobin concentration (MCHC)	0.087903	0.21897	0.22235	0.887	0.695
hematology	mean RBC corpuscular volume (MCV)	0.34395	0.33075	0.62470	0.550	0.317
hematology	measured hemoglobin (mHGB)	0.34677	0.19255	0.69219	0.352	0.0949
hematology	monocyte differential (percent of total WBC)	-0.29315	0.26910	-0.73136	0.647	0.296
hematology	neutrophil differential (percent of total WBC)	-7.3081	1.8133	-2.2937	0.0293	0.00143
hematology	platelet count (PLT; units per volume x 10³)	-154.14	128.34	-1.7342	0.624	0.251
hematology	RBC corpuscular distribution width (RDW)	-0.52056	0.26422	-1.7030	0.267	0.0705
hematology	RBC corpuscular hemoglobin concentration mean (CHCM)	-0.24032	0.20907	-0.67231	0.531	0.271
hematology	red blood cell count (RBC; per volume x 10⁶)	0.12315	0.15715	0.20251	0.691	0.447
hematology	reticulocyte count (Retic; units per volume x 10⁹)	-63.568	27.168	-2.2382	0.311	0.0359
hematology	reticulocyte differential (percent of total RBC)	-0.70028	0.27037	-2.1565	0.250	0.0224
hematology	white blood cell count (WBC; units per volume x 10³)	0.71020	0.64974	0.65658	0.500	0.294
holeboard	number of hole pokes by individual hole number, 20 min test, 1	-1.3875	0.71721	-1.3270	0.485	0.0619
holeboard	number of hole pokes by individual hole number, 20 min test, 2	-0.87302	0.46868	-1.2350	0.572	0.0717
holeboard	number of hole pokes by individual hole number, 20 min test, 3	-0.85000	0.56246	-1.3270	0.661	0.141
holeboard	number of hole pokes by individual hole number, 20 min test, 4	-1.1125	0.63633	-1.0532	0.553	0.0900
holeboard	number of hole pokes by individual hole number, 20 min test, 5	-0.35000	0.37066	-0.47373	0.794	0.352
holeboard	number of hole pokes by individual hole number, 20 min test, 6	0.14221	0.27378	0.41842	0.932	0.607
holeboard	number of hole pokes by individual hole number, 20 min test, 7	-0.30000	0.39853	-0.81447	0.905	0.457
holeboard	number of hole pokes by individual hole number, 20 min test, 8	0.64445	0.49971	1.1623	0.741	0.207
holeboard	number of hole pokes by individual hole number, 20 min test, 9	-0.062500	0.36550	-0.032098	0.984	0.865
holeboard	number of hole pokes by individual hole number, 20 min test, 10	0.24663	0.28311	0.68621	0.867	0.390
holeboard	number of hole pokes by individual hole number, 20 min test, 11	0.43960	0.54011	1.0587	0.857	0.422
holeboard	number of hole pokes by individual hole number, 20 min test, 12	-1.1944	0.40674	-1.8120	0.184	0.00610
holeboard	number of hole pokes by individual hole number, 20 min test, 13	-0.64522	0.69864	-0.56312	0.750	0.363
holeboard	number of hole pokes by individual hole number, 20 min test, 14	0.18750	0.46044	0.39643	0.906	0.687
holeboard	number of hole pokes by individual hole number, 20 min test, 15	0.65000	1.1751	1.0926	0.886	0.584
holeboard	number of hole pokes by individual hole number, 20 min test, 16	-0.16250	0.57221	-0.11326	0.938	0.778
holeboard	total number of hole pokes, 20 min test	-4.7500	3.7411	-0.58901	0.501	0.213
light / dark	fecal boli count, 20 min test	-2.2951	1.1226	-2.4048	0.386	0.0558
light / dark	latency to enter dark zone, 20 min test	-75.834	44.116	-1.5120	0.529	0.0956
light / dark	number of transitions between light and dark zones, 20 min test	12.709	8.4045	1.2496	0.438	0.141
light / dark	percentage of total time in dark zone, 20 min test	-3.6883	4.4333	-0.54186	0.722	0.412
light / dark	percentage of total time in light zone, 20 min test	3.6883	4.4333	0.53873	0.720	0.412
light / dark	time mobile in dark zone, 20 min test	23.755	11.443	1.1088	0.223	0.0460
light / dark	time mobile in light zone, 20 min test	12.633	16.557	0.51851	0.702	0.451
light / dark	time spent in dark zone, 20 min test	32.674	52.657	0.71668	0.846	0.539
light / dark	time spent in light zone, 20 min test	-32.674	52.657	-0.71668	0.846	0.539
open field	average speed in center of arena, 20 min test	-0.0095000	0.38835	-0.12857	0.998	0.981
open field	average speed in periphery of arena, 20 min test	0.37942	0.14018	0.90533	0.0629	0.0110
open field	distance traveled habituation ratio, 20 min test	-8.8382	8.3117	-0.75020	0.617	0.296
open field	distance traveled in center of arena, 20 min test	264.32	86.520	1.2079	0.0434	0.00460
open field	distance traveled in periphery of arena, 20 min test	186.26	153.09	0.29349	0.467	0.233
open field	distance traveled slope, 20 min test	-6.4075	7.7506	-0.55093	0.707	0.415
open field	distance traveled, 20 min test, 1st 5min	163.97	78.609	0.91345	0.178	0.0450
open field	distance traveled, 20 min test, 2nd 5min	88.077	48.114	0.48793	0.248	0.0768
open field	distance traveled, 20 min test, 3rd 5min	132.23	41.143	0.94866	0.0310	0.00305
open field	distance traveled, 20 min test, 4th 5min	91.787	53.896	0.53382	0.284	0.0986
open field	number of clockwise revolution episodes, 20 min test	2.2826	1.4861	0.86716	0.470	0.135
open field	number of counter-clockwise revolution episodes, 20 min test	3.4750	1.2822	1.3575	0.107	0.0107
open field	number of fecal boli, 20 min test	-0.54175	1.4471	-0.14981	0.868	0.713
open field	number of rears in 5 min bins, 20 min test, 1st 5min	2.8630	1.6213	0.58679	0.301	0.0873
open field	number of rears in 5 min bins, 20 min test, 2nd 5min	4.3625	2.2526	0.80841	0.263	0.0617
open field	number of rears in 5 min bins, 20 min test, 3rd 5min	6.1750	3.0604	1.0669	0.228	0.0521
open field	number of rears in 5 min bins, 20 min test, 4th 5min	8.5302	3.5000	1.4785	0.155	0.0205
open field	percentage of total time in center of arena, 20 min test	8.4875	3.0220	1.5731	0.122	0.00853
open field	percentage of total time in center of arena, slope, 20 min test	3.1256	1.1433	1.8074	0.277	0.0101
open field	percentage of total time in center, habituation ratio, 20 min test	2.5669	1.0618	1.5328	0.332	0.0215
open field	percentage of total time in corners of arena, 20 min test	-14.680	4.1612	-2.1562	0.0382	0.00133
open field	percentage of total time in corners, habituation ratio, 20 min test	-1.1506	1.7467	-0.83666	0.877	0.515
open field	percentage of total time in corners, slope, 20 min test	-1.8870	1.7504	-1.1618	0.768	0.289
open field	permanence time in center of arena, 20 min test	101.85	36.263	1.5731	0.122	0.00853
open field	permanence time in corners of arena, 20 min test	-176.16	49.934	-2.1562	0.0382	0.00133
open field	permanence time in periphery of arena, 20 min test	-101.83	36.267	-1.5731	0.122	0.00855
open field	total distance traveled, 20 min test	482.94	179.13	0.84239	0.0601	0.0112
open field	total number of rears, 20 min test	20.957	8.8438	1.0885	0.130	0.0240
open field	whole arena average speed, 20 min test	0.40322	0.14919	0.85007	0.0594	0.0111
open field	whole arena resting time, 20 min test	-43.090	19.203	-0.63580	0.119	0.0321
open field	whole arena time spent mobile, 20 min test	43.199	19.217	0.88330	0.119	0.0318
open field	whole arena time spent vertical, 20 min test	17.853	8.6314	1.2806	0.254	0.0468
startle / PPI	average baseline movement during background noise	1.6800	1.7143	1.0445	0.816	0.343
startle / PPI	average of each corrected maximum percent pre-pulse inhibition value	-0.00095864	0.11414	-0.10880	0.995	0.993
startle / PPI	average of each corrected percent pre-pulse inhibition value	0.0087671	0.11190	0.0021041	0.972	0.939
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	10.337	11.959	1.1882	0.879	0.401
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-2.0138	13.074	-0.24265	0.961	0.880
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-8.1960	12.143	-0.86950	0.771	0.510
startle / PPI	average startle response to full pulse (120 dB)	57.043	36.374	1.2025	0.343	0.139
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	44.386	46.817	0.99501	0.595	0.359
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	55.700	46.381	1.1853	0.468	0.248
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	68.933	44.564	1.4644	0.338	0.143
startle / PPI	average startle response to pre-pulse, 74dB sound pressure level	5.32	4.2098	2.2477	0.748	0.226
startle / PPI	average startle response to pre-pulse, 78dB sound pressure level	1.0000	3.4395	0.63328	0.961	0.775
startle / PPI	average startle response to pre-pulse, 82dB sound pressure level	2.52	3.3468	0.90270	0.805	0.463
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	0.12658	0.13331	1.2319	0.869	0.357
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-0.027285	0.13904	-0.34104	0.963	0.847
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-0.072993	0.13362	-0.73194	0.796	0.593
startle / PPI	corrected average startle response to full pulse (120 dB) minus average baseline movement during background noise	55.249	36.884	1.1741	0.373	0.156
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 74dB sound pressure level	39.600	47.820	0.91754	0.644	0.422
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 78dB sound pressure level	61.887	43.964	1.2781	0.388	0.181
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 82dB sound pressure level	66.413	45.086	1.4482	0.357	0.161
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	0.13399	0.13770	1.1882	0.860	0.346
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-0.040656	0.14663	-0.39106	0.910	0.785
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-0.096212	0.14319	-0.87732	0.738	0.512
startle / PPI	corrected maximum startle response to full pulse (120 dB) minus maximum baseline movement during background noise	198.48	135.22	1.1520	0.381	0.164
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 74dB sound pressure level	144.13	170.04	0.91328	0.632	0.411
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 78dB sound pressure level	206.54	157.88	1.2141	0.426	0.210
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 82dB sound pressure level	261.23	162.26	1.5154	0.309	0.128
startle / PPI	maximum baseline movement during background noise	2.7200	3.7660	0.82536	0.851	0.481
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	11.990	12.847	1.2655	0.890	0.365
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-3.3172	14.217	-0.36450	0.932	0.819
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-10.112	13.624	-1.0042	0.740	0.469
startle / PPI	maximum startle response to full pulse (120 dB)	201.35	134.58	1.1493	0.370	0.157
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	152.82	167.72	0.95888	0.601	0.378
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	207.09	159.44	1.2112	0.429	0.214
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	266.59	161.97	1.5378	0.302	0.121
startle / PPI	maximum startle response to pre-pulse, 74dB sound pressure level	9.7600	9.0753	1.9969	0.758	0.299
startle / PPI	maximum startle response to pre-pulse, 78dB sound pressure level	0.54667	9.4228	0.18245	0.996	0.955
startle / PPI	maximum startle response to pre-pulse, 82dB sound pressure level	5.3600	7.5045	0.73787	0.811	0.486

MULTIPLE (CATEGORICAL) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

Procedure	JaxKOMP-EAP Trait	Sex	Trait Effect	P-value
eye morphology	anterior chamber depth	females	12.0 %	0.106
eye morphology	anterior chamber depth	males	0.0 %	1.0
eye morphology	anterior chamber depth	both	6.0 %	0.141
eye morphology	bulging eye	females	12.0 %	0.0825
eye morphology	bulging eye	males	0.0 %	1.0
eye morphology	bulging eye	both	6.0 %	0.115
eye morphology	cornea	females	21.0 %	0.0188
eye morphology	cornea	males	25.0 %	0.000277
eye morphology	cornea	both	22.0 %	0.0000987
eye morphology	cornea opacity	females	12.0 %	0.150
eye morphology	cornea opacity	males	1.0 %	1.0
eye morphology	cornea opacity	both	6.0 %	0.249
eye morphology	cornea vascularization	females	12.0 %	0.127
eye morphology	cornea vascularization	males	1.0 %	1.0
eye morphology	cornea vascularization	both	6.0 %	0.234
eye morphology	corneal deposits	females	12.0 %	0.143
eye morphology	corneal deposits	males	1.0 %	1.0
eye morphology	corneal deposits	both	6.0 %	0.208
eye morphology	corneal mineralization	females	12.0 %	0.152
eye morphology	corneal mineralization	males	1.0 %	1.0
eye morphology	corneal mineralization	both	6.0 %	0.200
eye morphology	corneal scleralization	females	12.0 %	0.146
eye morphology	corneal scleralization	males	1.0 %	1.0
eye morphology	corneal scleralization	both	6.0 %	0.202
eye morphology	corneal ulcer	females	12.0 %	0.111
eye morphology	corneal ulcer	males	1.0 %	1.0
eye morphology	corneal ulcer	both	6.0 %	0.153
eye morphology	eye closure	females	12.0 %	0.0823
eye morphology	eye closure	males	0.0 %	1.0
eye morphology	eye closure	both	6.0 %	0.115
eye morphology	eye hemorrhage or blood presence	females	23.0 %	0.00342
eye morphology	eye hemorrhage or blood presence	males	1.0 %	1.0
eye morphology	eye hemorrhage or blood presence	both	11.0 %	0.00821
eye morphology	eyelid morphology	females	12.0 %	0.0905
eye morphology	eyelid morphology	males	0.0 %	1.0
eye morphology	eyelid morphology	both	6.0 %	0.123
eye morphology	eyes (present, absent)	females	12.0 %	0.00929
eye morphology	eyes (present, absent)	males	0.0 %	1.0
eye morphology	eyes (present, absent)	both	6.0 %	0.00961
eye morphology	fusion between cornea and lens	females	98.0 %	1.01e-12
eye morphology	fusion between cornea and lens	males	36.0 %	0.000468
eye morphology	fusion between cornea and lens	both	67.0 %	2.29e-14
eye morphology	iris pigmentation	females	12.0 %	0.103
eye morphology	iris pigmentation	males	1.0 %	1.0
eye morphology	iris pigmentation	both	6.0 %	0.218
eye morphology	iris transillumination	females	12.0 %	0.0842
eye morphology	iris transillumination	males	1.0 %	1.0
eye morphology	iris transillumination	both	6.0 %	0.191
eye morphology	irispupil	females	12.0 %	0.141
eye morphology	irispupil	males	3.0 %	1.0
eye morphology	irispupil	both	6.0 %	0.226
eye morphology	lacrimation	females	3.0 %	1.0
eye morphology	lacrimation	males	12.0 %	0.0594
eye morphology	lacrimation	both	6.0 %	0.106
eye morphology	lens	females	99.0 %	3.76e-13
eye morphology	lens	males	37.0 %	0.00128
eye morphology	lens	both	68.0 %	1.99e-14
eye morphology	lens opacity	females	98.0 %	3.90e-12
eye morphology	lens opacity	males	36.0 %	0.00270
eye morphology	lens opacity	both	67.0 %	4.33e-13
eye morphology	narrow eye opening	females	12.0 %	0.121
eye morphology	narrow eye opening	males	1.0 %	1.0
eye morphology	narrow eye opening	both	6.0 %	0.211
eye morphology	optic disc	females	98.0 %	3.36e-12
eye morphology	optic disc	males	36.0 %	0.00171
eye morphology	optic disc	both	67.0 %	1.80e-13
eye morphology	persistence of hyaloid vascular system	females	98.0 %	2.31e-11
eye morphology	persistence of hyaloid vascular system	males	36.0 %	0.00295
eye morphology	persistence of hyaloid vascular system	both	67.0 %	2.21e-12
eye morphology	pupil dilation	females	12.0 %	0.106
eye morphology	pupil dilation	males	1.0 %	1.0
eye morphology	pupil dilation	both	6.0 %	0.236
eye morphology	pupil light response	females	12.0 %	0.109
eye morphology	pupil light response	males	1.0 %	1.0
eye morphology	pupil light response	both	6.0 %	0.236
eye morphology	pupil position	females	12.0 %	0.112
eye morphology	pupil position	males	3.0 %	1.0
eye morphology	pupil position	both	6.0 %	0.239
eye morphology	pupil shape	females	12.0 %	0.122
eye morphology	pupil shape	males	2.0 %	1.0
eye morphology	pupil shape	both	6.0 %	0.249
eye morphology	retina	females	98.0 %	9.31e-12
eye morphology	retina	males	36.0 %	0.00399
eye morphology	retina	both	67.0 %	1.08e-12
eye morphology	retinal blood vessels	females	98.0 %	5.99e-13
eye morphology	retinal blood vessels	males	36.0 %	0.000679
eye morphology	retinal blood vessels	both	67.0 %	3.57e-14
eye morphology	retinal blood vessels pattern	females	98.0 %	5.95e-12
eye morphology	retinal blood vessels pattern	males	36.0 %	0.00175
eye morphology	retinal blood vessels pattern	both	67.0 %	2.22e-13
eye morphology	retinal blood vessels structure	females	98.0 %	2.73e-12
eye morphology	retinal blood vessels structure	males	36.0 %	0.00107
eye morphology	retinal blood vessels structure	both	67.0 %	1.12e-13
eye morphology	retinal pigmentation	females	98.0 %	6.24e-12
eye morphology	retinal pigmentation	males	36.0 %	0.00432
eye morphology	retinal pigmentation	both	67.0 %	1.10e-12
eye morphology	retinal structure	females	98.0 %	3.07e-12
eye morphology	retinal structure	males	36.0 %	0.00130
eye morphology	retinal structure	both	67.0 %	1.59e-13
eye morphology	synechia	females	98.0 %	3.91e-13
eye morphology	synechia	males	36.0 %	0.000635
eye morphology	synechia	both	67.0 %	1.07e-14
eye morphology	vitreous	females	98.0 %	1.02e-12
eye morphology	vitreous	males	36.0 %	0.000531
eye morphology	vitreous	both	67.0 %	2.31e-14

GENOTYPE CORRELATION PLOT

Correlate Asmt^em1(IMPC)J/Mmjax -/- with genotype: