MPD: JaxKOMP-EAP genotype: Bpi<sup>em1(IMPC)J</sup>/Mmjax -/-

JaxKOMP-EAP effect sizes: Bpi^em1(IMPC)J/Mmjax -/- Gene Bpi

MULTIPLE (NUMERIC) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

Procedure	JaxKOMP-EAP Trait	Trait Effect	Trait Effect SE	Trait Effect RankZ	Adjusted p-value	Unadjusted p-value
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 6 kHz pip	0.91146	2.1129	0.0043218	0.903	0.672
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 12 kHz pip	2.7695	2.1202	0.63629	0.697	0.211
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 18 kHz pip	3.3616	4.0534	0.51060	0.755	0.419
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 24 kHz pip	3.3437	2.8927	0.44105	0.651	0.265
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 30 kHz pip	5.8333	3.0752	0.90021	0.401	0.0760
body composition	body length	-0.0066611	0.027117	0.10941	0.920	0.807
body composition	body weight (at time of DXA)	1.1554	0.59172	1.0783	0.184	0.0571
body composition	bone area, whole body scan, head excluded	-0.029453	0.13397	0.049169	0.927	0.827
body composition	bone mineral content of whole body scan, head excluded	-0.0048293	0.010220	-0.15075	0.833	0.639
body composition	bone mineral content to body weight ratio	-0.00034398	0.00037637	-0.27087	0.625	0.366
body composition	bone mineral density of whole body scan, head excluded	-0.00029306	0.00057062	-0.27456	0.809	0.610
body composition	fat tissue mass of whole body scan, head excluded	0.78659	0.39723	1.1281	0.217	0.0540
body composition	fat tissue mass to body weight ratio	0.022947	0.013425	1.0052	0.268	0.0943
body composition	lean tissue mass of whole body scan, head excluded	0.040682	0.34010	-0.060108	0.966	0.905
body composition	lean tissue mass to body weight ratio	-0.0097537	0.011964	-0.58414	0.660	0.419
body composition	percent fat, whole body scan, head excluded	2.0244	1.2833	0.95442	0.321	0.122
body composition	ratio of soft-tissue attenuation coefficients	-0.0022239	0.0014261	-0.94866	0.327	0.126
body composition	tissue area	0.065081	0.16192	0.42524	0.883	0.690
body composition	total tissue mass, whole body scan, head excluded	0.83734	0.18879	1.3654	0.00247	0.0000607
clinical blood chemistry	alanine transaminase (plasma ALT)	3.5357	3.5396	0.31473	0.690	0.330
clinical blood chemistry	albumin (plasma Alb)	0.58333	0.44198	0.84284	0.518	0.202
clinical blood chemistry	alkaline phosphatase (plasma ALP)	6.8468	3.5329	0.68028	0.232	0.0676
clinical blood chemistry	aspartate transaminase (plasma AST)	-3.5595	21.568	-0.17816	0.971	0.871
clinical blood chemistry	aspartate transaminase to alanine transaminase ratio (plasma AST:ALT)	-0.42855	0.37046	-1.2456	0.661	0.261
clinical blood chemistry	blood urea nitrogen (BUN)	1.9643	1.0772	0.77177	0.281	0.0832
clinical blood chemistry	calcium (plasma Ca)	-0.025025	0.060254	0.16929	0.826	0.682
clinical blood chemistry	creatinine (plasma)	0.034690	0.024929	0.93057	0.414	0.181
clinical blood chemistry	glucose (plasma GLU, no fast)	-8.5984	14.560	-0.037858	0.740	0.561
clinical blood chemistry	HDL cholesterol (plasma HDL)	3.2673	3.6833	0.45679	0.677	0.386
clinical blood chemistry	HDL cholesterol to total cholesterol ratio	0.010774	0.0092811	0.43855	0.594	0.259
clinical blood chemistry	phosphorus (plasma phosphate)	-0.56466	0.20629	-0.96326	0.106	0.0127
clinical blood chemistry	total bilirubin (plasma TBIL)	-0.0091667	0.010394	-0.68432	0.728	0.388
clinical blood chemistry	total cholesterol (plasma CHOL, no fast)	3.6964	4.5913	0.40847	0.726	0.430
clinical blood chemistry	total protein (plasma TP)	0.22018	0.58607	0.11301	0.865	0.711
clinical blood chemistry	triglyceride (plasma TG, no fast)	10.351	11.059	0.77497	0.644	0.361
EKG	duration of PQ interval	1.3657	0.92258	1.5591	0.786	0.235
EKG	duration of PR interval	0.87298	0.60761	1.0454	0.807	0.246
EKG	duration of QRS interval	-0.43685	0.82979	-1.3162	0.959	0.635
EKG	duration of QT interval	-0.64597	0.87422	-0.46115	0.898	0.514
EKG	duration of QTC interval, calculated by dividing QT interval by square root of preceding RR interval	0.0073439	1.1258	0.066543	0.999	0.995
EKG	duration of RR interval	-2.4567	1.5720	-1.0248	0.638	0.216
EKG	duration of ST interval	-0.17714	1.5766	0.036277	0.975	0.918
EKG	heart rate coefficient of variation (signal intensity)	-3.7806	1.2878	-2.7250	0.770	0.0607
EKG	heart rate variability, mean of differences between sequential beats; beats per min	-27.058	9.3698	-2.7250	0.761	0.0631
EKG	heart rate, beats per min	15.077	13.034	0.66126	0.722	0.331
EKG	mean R amplitude, mean amplitude of signal measured from isoelectric line to peak of QRS	0.14400	0.16116	0.97767	0.759	0.437
EKG	mean SR amplitude, mean amplitude of signal measured from signal minimum line to peak of QRS	0.13604	0.16557	0.69424	0.767	0.471
EKG	number of signals	-12.266	6.3059	-1.8966	0.667	0.147
EKG	proportion of number pairs of successive beat-to-beat intervals that exceed 50 ms	-9.1870	5.1645	-1.6339	0.814	0.173
EKG	QT dispersion, measured as inter-lead variability of QT intervals	-17.143	5.3349	-2.9464	0.858	0.0488
EKG	QTc dispersion, calculated as rate-corrected QT dispersion	-17.720	5.8396	-2.9464	0.748	0.0561
EKG	root mean square of successive differences of neighboring RR intervals	-8.4176	3.0071	-3.1545	0.843	0.0679
glucose tolerance test	amount glucose injected	-9.5850	14.372	-1.8625	0.813	0.511
glucose tolerance test	plasma glucose, 0min	9.0535	6.7625	0.68400	0.398	0.193
glucose tolerance test	plasma glucose, 15min	4.3264	31.963	0.24400	0.960	0.893
glucose tolerance test	plasma glucose, 30min	-16.977	32.201	-0.40030	0.828	0.603
glucose tolerance test	plasma glucose, 60min	-23.590	18.312	-0.89403	0.534	0.210
glucose tolerance test	plasma glucose, 120min	1.6939	11.886	-0.012355	0.956	0.888
grip strength	body weight (at time of grip strength test)	0.48125	0.44040	0.65459	0.477	0.283
grip strength	forelimb and hindlimb grip strength (mean of trials), average	-18.096	6.1664	-0.98065	0.0404	0.00635
grip strength	forelimb and hindlimb grip strength (mean of trials), average normalized to bw	-0.96369	0.27284	-1.1782	0.0158	0.00140
grip strength	forelimb and hindlimb grip strength by trial, trial1	-23.925	7.6054	-1.3349	0.0455	0.00372
grip strength	forelimb and hindlimb grip strength by trial, trial2	-19.354	9.7591	-0.97129	0.218	0.0566
grip strength	forelimb and hindlimb grip strength by trial, trial3	-11.962	7.8604	-0.55599	0.380	0.139
grip strength	forelimb grip strength (mean of trials), average	-8.1624	5.0766	-0.75223	0.342	0.118
grip strength	forelimb grip strength (mean of trials), average normalized to bw	-0.46598	0.22668	-0.93022	0.210	0.0486
grip strength	forelimb grip strength by trial, trial1	-4.4782	5.3808	-0.25995	0.734	0.412
grip strength	forelimb grip strength by trial, trial2	-9.2701	5.5746	-0.78146	0.392	0.107
grip strength	forelimb grip strength by trial, trial3	-10.931	5.6622	-0.90806	0.291	0.0630
heart weight	heart weight, normalized to body weight	-0.065782	0.12529	-0.71186	0.772	0.604
heart weight	heart weight, weight	0.23921	3.3086	-0.34523	0.966	0.943
hematology	basophil differential (percent of total WBC)	-0.072619	0.050755	-1.0016	0.604	0.168
hematology	calculated hemoglobin (cHGB)	0.11310	0.24787	0.046951	0.838	0.653
hematology	eosinophil differential (percent of total WBC)	-0.34513	0.25484	-0.85062	0.582	0.192
hematology	hematocrit (HCT)	0.61757	0.88516	0.31972	0.723	0.493
hematology	hemoglobin concentration distribution width (HDW)	-0.057155	0.027963	-1.4703	0.292	0.0551
hematology	large unstained cells (percent of total WBC)	-0.021869	0.070058	-0.12452	0.898	0.758
hematology	lymphocyte differential (percent of total WBC)	2.9954	2.1656	0.99769	0.442	0.182
hematology	mean corpuscular hemoglobin (CHr)	0.017544	0.090534	0.17299	0.927	0.848
hematology	mean platelet volume (MPV)	-0.15218	0.090305	-1.0460	0.276	0.107
hematology	mean RBC corpuscular hemoglobin (MCH)	0.13313	0.13762	0.48620	0.701	0.346
hematology	mean RBC corpuscular hemoglobin concentration (MCHC)	-0.011885	0.17823	-0.0095883	0.979	0.947
hematology	mean RBC corpuscular volume (MCV)	0.20476	0.31074	0.39550	0.728	0.517
hematology	measured hemoglobin (mHGB)	0.21429	0.30600	0.31918	0.731	0.492
hematology	monocyte differential (percent of total WBC)	-0.24759	0.14563	-0.59833	0.444	0.105
hematology	neutrophil differential (percent of total WBC)	-2.5782	2.0768	-1.0367	0.477	0.229
hematology	platelet count (PLT; units per volume x 10³)	75.238	58.154	1.0204	0.580	0.210
hematology	RBC corpuscular distribution width (RDW)	-0.61509	0.48309	-1.8960	0.480	0.218
hematology	RBC corpuscular hemoglobin concentration mean (CHCM)	-0.18333	0.10320	-0.54045	0.280	0.0909
hematology	red blood cell count (RBC; per volume x 10⁶)	0.077766	0.18151	-0.0027365	0.839	0.673
hematology	reticulocyte count (Retic; units per volume x 10⁹)	-10.099	23.193	-0.35992	0.893	0.668
hematology	reticulocyte differential (percent of total RBC)	-0.17321	0.28659	-0.54425	0.815	0.552
hematology	white blood cell count (WBC; units per volume x 10³)	-1.7543	0.51103	-1.0227	0.0254	0.00279
holeboard	number of hole pokes by individual hole number, 20 min test, 1	1.9098	0.69675	1.6400	0.290	0.00958
holeboard	number of hole pokes by individual hole number, 20 min test, 2	-0.12555	0.42444	-0.068416	0.953	0.769
holeboard	number of hole pokes by individual hole number, 20 min test, 3	0.42976	0.46148	0.78983	0.812	0.358
holeboard	number of hole pokes by individual hole number, 20 min test, 4	2.1052	0.73266	1.8477	0.229	0.00686
holeboard	number of hole pokes by individual hole number, 20 min test, 5	0.54171	0.36296	0.93165	0.650	0.145
holeboard	number of hole pokes by individual hole number, 20 min test, 6	0.016040	0.32308	0.097993	0.999	0.961
holeboard	number of hole pokes by individual hole number, 20 min test, 7	-0.14104	0.30267	-0.41471	0.958	0.644
holeboard	number of hole pokes by individual hole number, 20 min test, 8	0.37777	0.35256	0.77379	0.790	0.291
holeboard	number of hole pokes by individual hole number, 20 min test, 9	1.0817	0.38461	1.6527	0.255	0.00801
holeboard	number of hole pokes by individual hole number, 20 min test, 10	0.093473	0.31452	0.31464	0.952	0.768
holeboard	number of hole pokes by individual hole number, 20 min test, 11	0.065688	0.20889	0.20238	0.954	0.755
holeboard	number of hole pokes by individual hole number, 20 min test, 12	0.65819	0.51845	1.1019	0.659	0.213
holeboard	number of hole pokes by individual hole number, 20 min test, 13	-0.086607	0.60197	-0.011808	0.977	0.886
holeboard	number of hole pokes by individual hole number, 20 min test, 14	0.53540	0.42273	0.88621	0.660	0.214
holeboard	number of hole pokes by individual hole number, 20 min test, 15	0.12611	0.59834	0.25753	0.944	0.834
holeboard	number of hole pokes by individual hole number, 20 min test, 16	0.96405	0.99572	0.86150	0.730	0.340
holeboard	total number of hole pokes, 20 min test	8.6244	4.1129	1.1965	0.235	0.0433
light / dark	fecal boli count, 20 min test	0.74733	0.52815	0.85091	0.575	0.164
light / dark	latency to enter dark zone, 20 min test	-23.998	58.512	-0.53248	0.907	0.684
light / dark	number of transitions between light and dark zones, 20 min test	14.292	6.7169	1.3605	0.238	0.0390
light / dark	percentage of total time in dark zone, 20 min test	-5.7381	4.9121	-0.88240	0.614	0.249
light / dark	percentage of total time in light zone, 20 min test	5.7381	4.9121	0.88040	0.615	0.249
light / dark	time mobile in dark zone, 20 min test	18.313	10.515	0.90253	0.325	0.0886
light / dark	time mobile in light zone, 20 min test	35.132	12.022	1.5036	0.0545	0.00547
light / dark	time spent in dark zone, 20 min test	-41.759	58.213	-0.41152	0.813	0.477
light / dark	time spent in light zone, 20 min test	41.759	58.213	0.41152	0.813	0.477
open field	average speed in center of arena, 20 min test	0.32639	0.42764	0.50158	0.757	0.449
open field	average speed in periphery of arena, 20 min test	0.52307	0.11295	1.3054	0.000858	0.0000336
open field	distance traveled habituation ratio, 20 min test	-8.3695	6.8583	-0.72029	0.549	0.229
open field	distance traveled in center of arena, 20 min test	245.14	86.054	1.1181	0.0556	0.00671
open field	distance traveled in periphery of arena, 20 min test	463.05	108.53	1.2626	0.00263	0.000107
open field	distance traveled slope, 20 min test	-8.0419	6.4291	-0.70816	0.543	0.218
open field	distance traveled, 20 min test, 1st 5min	249.54	64.899	1.4588	0.00741	0.000393
open field	distance traveled, 20 min test, 2nd 5min	157.97	44.143	1.1832	0.0123	0.000872
open field	distance traveled, 20 min test, 3rd 5min	141.24	39.151	1.0229	0.0128	0.000800
open field	distance traveled, 20 min test, 4th 5min	170.90	33.025	1.2746	0.000213	0.00000570
open field	number of clockwise revolution episodes, 20 min test	2.0513	1.2239	0.77495	0.412	0.101
open field	number of counter-clockwise revolution episodes, 20 min test	3.6673	1.1352	1.4173	0.0475	0.00237
open field	number of fecal boli, 20 min test	-0.018659	0.75587	0.26476	0.995	0.980
open field	number of rears in 5 min bins, 20 min test, 1st 5min	4.7935	2.2059	1.0761	0.182	0.0353
open field	number of rears in 5 min bins, 20 min test, 2nd 5min	2.9888	2.4420	0.42533	0.522	0.228
open field	number of rears in 5 min bins, 20 min test, 3rd 5min	0.30806	2.9625	-0.24614	0.959	0.918
open field	number of rears in 5 min bins, 20 min test, 4th 5min	7.5520	3.2270	1.2960	0.166	0.0240
open field	percentage of total time in center of arena, 20 min test	2.6491	2.9665	0.38742	0.685	0.377
open field	percentage of total time in center of arena, slope, 20 min test	-1.1460	1.3324	-0.50616	0.812	0.394
open field	percentage of total time in center, habituation ratio, 20 min test	-1.3065	1.3460	-0.60811	0.791	0.337
open field	percentage of total time in corners of arena, 20 min test	-2.5770	3.5891	-0.15706	0.748	0.477
open field	percentage of total time in corners, habituation ratio, 20 min test	3.3748	1.5496	1.1671	0.405	0.0350
open field	percentage of total time in corners, slope, 20 min test	2.9225	1.4031	1.0528	0.453	0.0432
open field	permanence time in center of arena, 20 min test	31.795	35.600	0.38887	0.685	0.377
open field	permanence time in corners of arena, 20 min test	-30.934	43.071	-0.15706	0.748	0.477
open field	permanence time in periphery of arena, 20 min test	-31.748	35.615	-0.38887	0.686	0.378
open field	total distance traveled, 20 min test	713.51	147.55	1.3677	0.000475	0.0000173
open field	total number of rears, 20 min test	15.984	9.5117	0.75020	0.297	0.100
open field	whole arena average speed, 20 min test	0.59569	0.12291	1.3712	0.000458	0.0000167
open field	whole arena resting time, 20 min test	-78.910	14.496	-1.3885	0.0000840	0.00000234
open field	whole arena time spent mobile, 20 min test	78.777	14.492	1.5731	0.0000879	0.00000240
open field	whole arena time spent vertical, 20 min test	12.052	8.7788	0.83475	0.481	0.177
SHIRPA	locomotor activity (number of squares in the arena the mouse moves into with all four paws in first 30 s of test)	4.0769	1.7013	1.8160	0.178	0.0232
startle / PPI	average baseline movement during background noise	1.7654	1.2739	1.0941	0.720	0.175
startle / PPI	average of each corrected maximum percent pre-pulse inhibition value	-0.033199	0.056370	-0.40220	0.806	0.560
startle / PPI	average of each corrected percent pre-pulse inhibition value	-0.040125	0.054475	-0.46901	0.775	0.466
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-6.6565	5.9205	-0.68198	0.877	0.269
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-4.8387	7.4171	-0.51430	0.800	0.518
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	1.2960	5.0674	0.025924	0.925	0.800
startle / PPI	average startle response to full pulse (120 dB)	-4.2793	42.856	0.10317	0.967	0.921
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	18.814	47.400	0.60443	0.849	0.694
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	11.549	43.752	0.44203	0.878	0.793
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	1.0803	36.228	0.22537	0.994	0.976
startle / PPI	average startle response to pre-pulse, 74dB sound pressure level	0.87467	1.1162	0.65050	0.842	0.439
startle / PPI	average startle response to pre-pulse, 78dB sound pressure level	-1.6543	1.9416	-1.1385	0.857	0.400
startle / PPI	average startle response to pre-pulse, 82dB sound pressure level	2.8930	2.0882	1.0230	0.623	0.175
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-0.071877	0.061900	-0.64877	0.852	0.253
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-0.067080	0.081940	-0.63238	0.715	0.419
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	0.018583	0.059957	-0.0084116	0.898	0.758
startle / PPI	corrected average startle response to full pulse (120 dB) minus average baseline movement during background noise	-5.7157	42.491	0.076436	0.955	0.894
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 74dB sound pressure level	17.997	47.334	0.57773	0.858	0.706
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 78dB sound pressure level	13.036	43.920	0.48414	0.866	0.768
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 82dB sound pressure level	10.310	37.434	0.45287	0.880	0.785
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-0.074187	0.059847	-0.64359	0.826	0.223
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-0.037151	0.084068	-0.36846	0.855	0.661
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	0.011741	0.064018	-0.095475	0.949	0.856
startle / PPI	corrected maximum startle response to full pulse (120 dB) minus maximum baseline movement during background noise	-58.207	150.00	-0.14695	0.866	0.700
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 74dB sound pressure level	66.799	169.50	0.53197	0.843	0.696
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 78dB sound pressure level	12.013	162.65	0.23833	0.964	0.942
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 82dB sound pressure level	-4.0212	137.73	0.17961	0.988	0.977
startle / PPI	maximum baseline movement during background noise	2.8335	3.1114	0.85730	0.807	0.369
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-7.2487	5.8032	-0.68022	0.884	0.220
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-2.7861	7.9460	-0.31256	0.892	0.728
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	0.71190	5.7314	-0.093311	0.959	0.902
startle / PPI	maximum startle response to full pulse (120 dB)	-54.666	150.82	-0.12432	0.877	0.719
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	70.280	169.49	0.54818	0.837	0.681
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	9.5626	162.73	0.22537	0.974	0.953
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	4.3902	136.55	0.22394	0.984	0.975
startle / PPI	maximum startle response to pre-pulse, 74dB sound pressure level	3.4442	2.3829	0.96779	0.658	0.157
startle / PPI	maximum startle response to pre-pulse, 78dB sound pressure level	-3.7547	4.7735	-1.0397	0.827	0.437
startle / PPI	maximum startle response to pre-pulse, 82dB sound pressure level	8.0830	5.7810	1.0765	0.542	0.171

MULTIPLE (CATEGORICAL) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

Procedure	JaxKOMP-EAP Trait	Trait Effect	P-value
eye morphology	anterior chamber depth	1.0 %	1.0
eye morphology	bulging eye	1.0 %	1.00
eye morphology	cornea	5.0 %	0.344
eye morphology	cornea opacity	3.0 %	1.00
eye morphology	cornea vascularization	2.0 %	1.00
eye morphology	corneal deposits	1.0 %	1.00
eye morphology	corneal mineralization	1.0 %	1.00
eye morphology	corneal scleralization	2.0 %	1.00
eye morphology	corneal ulcer	1.0 %	1.00
eye morphology	eye closure	1.0 %	1.0
eye morphology	eye hemorrhage or blood presence	1.0 %	1.00
eye morphology	eyelid morphology	1.0 %	1.0
eye morphology	eyes (present, absent)	0.0 %	1.0
eye morphology	fusion between cornea and lens	3.0 %	1.00
eye morphology	iris pigmentation	2.0 %	1.00
eye morphology	iris transillumination	1.0 %	1.00
eye morphology	irispupil	3.0 %	1.00
eye morphology	lacrimation	3.0 %	1.0
eye morphology	lens	9.0 %	1.0
eye morphology	lens opacity	5.0 %	0.467
eye morphology	narrow eye opening	1.0 %	1.0
eye morphology	optic disc	3.0 %	1.00
eye morphology	persistence of hyaloid vascular system	9.0 %	1.00
eye morphology	pupil dilation	2.0 %	1.0
eye morphology	pupil light response	2.0 %	1.00
eye morphology	pupil position	4.0 %	1.00
eye morphology	pupil shape	3.0 %	1.00
eye morphology	retina	8.0 %	0.428
eye morphology	retinal blood vessels	3.0 %	1.0
eye morphology	retinal blood vessels pattern	4.0 %	1.00
eye morphology	retinal blood vessels structure	3.0 %	1.00
eye morphology	retinal pigmentation	10.0 %	0.371
eye morphology	retinal structure	3.0 %	1.00
eye morphology	synechia	3.0 %	1.00
eye morphology	vitreous	3.0 %	1.00
SHIRPA	activity body position	1.0 %	1.00
SHIRPA	aggression	1.0 %	1.0
SHIRPA	body length	0.0 %	1.00
SHIRPA	body position	0.0 %	1.0
SHIRPA	body thickness	0.0 %	1.0
SHIRPA	coat color abdomen	4.0 %	1.0
SHIRPA	coat color back	0.0 %	1.00
SHIRPA	coat color head	0.0 %	1.0
SHIRPA	coat color pattern abdomen	1.0 %	1.0
SHIRPA	coat color pattern back	0.0 %	1.0
SHIRPA	coat color pattern head	0.0 %	1.00
SHIRPA	coat hair abdomen texture appearance	2.0 %	1.0
SHIRPA	coat hair back texture appearance	0.0 %	1.0
SHIRPA	coat hair distribution abdomen	1.0 %	1.00
SHIRPA	coat hair distribution back	0.0 %	1.0
SHIRPA	coat hair distribution head	1.0 %	1.0
SHIRPA	coat hair head texture appearance	0.0 %	1.0
SHIRPA	contact righting	5.0 %	1.00
SHIRPA	ear morphology	0.0 %	1.0
SHIRPA	fat distribution	0.0 %	1.00
SHIRPA	forelimb digit number	0.0 %	1.00
SHIRPA	forelimb digit position	0.0 %	1.0
SHIRPA	forelimb digit shape	0.0 %	1.0
SHIRPA	forelimb digit size	0.0 %	1.0
SHIRPA	forelimb footpads	0.0 %	1.0
SHIRPA	forelimb nail length	0.0 %	1.0
SHIRPA	forelimb nail number	0.0 %	1.0
SHIRPA	forelimb nail position	0.0 %	1.0
SHIRPA	forelimb nail shape	0.0 %	1.0
SHIRPA	forelimbs position	0.0 %	1.0
SHIRPA	forelimbs shape	0.0 %	1.0
SHIRPA	forelimbs size	0.0 %	1.0
SHIRPA	forepaw position	0.0 %	1.0
SHIRPA	forepaw shape	0.0 %	1.0
SHIRPA	forepaw size	0.0 %	1.0
SHIRPA	gait (fluidity)	0.0 %	1.00
SHIRPA	genitalia morphology	0.0 %	1.00
SHIRPA	genitalia presence	0.0 %	1.0
SHIRPA	genitalia size	0.0 %	1.0
SHIRPA	head bobbing	0.0 %	1.0
SHIRPA	head morphology	0.0 %	1.0
SHIRPA	head size	0.0 %	1.00
SHIRPA	hindlimb digit number	0.0 %	1.00
SHIRPA	hindlimb digit position	0.0 %	1.0
SHIRPA	hindlimb digit shape	0.0 %	1.0
SHIRPA	hindlimb digit size	0.0 %	1.00
SHIRPA	hindlimb nail length	0.0 %	1.00
SHIRPA	hindlimb nail number	0.0 %	1.00
SHIRPA	hindlimb nail position	0.0 %	1.0
SHIRPA	hindlimb nail shape	0.0 %	1.0
SHIRPA	hindlimbs footpads	0.0 %	1.0
SHIRPA	hindlimbs position	0.0 %	1.0
SHIRPA	hindlimbs shape	0.0 %	1.0
SHIRPA	hindlimbs size	0.0 %	1.0
SHIRPA	hindpaw position	0.0 %	1.0
SHIRPA	hindpaw shape	0.0 %	1.0
SHIRPA	hindpaw size	0.0 %	1.0
SHIRPA	limb grasp	7.0 %	0.624
SHIRPA	lower lip morphology	0.0 %	1.0
SHIRPA	lower teeth appearance	0.0 %	1.00
SHIRPA	mouth morphology	0.0 %	1.00
SHIRPA	salivation	0.0 %	1.0
SHIRPA	skin color back paws	0.0 %	1.0
SHIRPA	skin color ear	0.0 %	1.0
SHIRPA	skin color front paws	0.0 %	1.0
SHIRPA	skin color snout	0.0 %	1.0
SHIRPA	skin color tail	0.0 %	1.0
SHIRPA	skin color whole body	0.0 %	1.0
SHIRPA	skin texture back paw	0.0 %	1.0
SHIRPA	skin texture ear	0.0 %	1.0
SHIRPA	skin texture front paws	0.0 %	1.0
SHIRPA	skin texture snout	0.0 %	1.0
SHIRPA	skin texture tail	0.0 %	1.0
SHIRPA	skin texture whole body	0.0 %	1.00
SHIRPA	snout size	0.0 %	1.0
SHIRPA	startle response	0.0 %	1.00
SHIRPA	tail curvature	0.0 %	1.0
SHIRPA	tail elevation	1.0 %	1.0
SHIRPA	tail length	0.0 %	1.00
SHIRPA	tail morphology	0.0 %	1.00
SHIRPA	tail presence	0.0 %	1.0
SHIRPA	tail shape	0.0 %	1.00
SHIRPA	tail thickness	0.0 %	1.0
SHIRPA	teeth presence	0.0 %	1.00
SHIRPA	transfer arousal	1.0 %	1.0
SHIRPA	tremor	0.0 %	1.00
SHIRPA	trunk curl	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	0.0 %	1.00
SHIRPA	upper lip morphology	0.0 %	1.0
SHIRPA	upper teeth appearance	0.0 %	1.00
SHIRPA	vibrissae appearance	1.0 %	1.0
SHIRPA	vibrissae presence	2.0 %	1.0
SHIRPA	vocalization	2.0 %	1.00

GENOTYPE CORRELATION PLOT

Correlate Bpi^em1(IMPC)J/Mmjax -/- with genotype: