MPD: JaxKOMP-EAP genotype: Fars2<sup>em1(IMPC)J</sup>/Mmjax -/+

JaxKOMP-EAP effect sizes: Fars2^em1(IMPC)J/Mmjax -/+ Gene Fars2

MULTIPLE (NUMERIC) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

Procedure	JaxKOMP-EAP Trait	Trait Effect	Trait Effect SE	Trait Effect RankZ	Adjusted p-value	Unadjusted p-value
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 6 kHz pip	2.2500	1.3829	0.43389	0.670	0.245
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 12 kHz pip	2.1927	3.2757	0.53696	0.873	0.572
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 18 kHz pip	6.8678	4.1685	1.0334	0.605	0.241
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 24 kHz pip	3.7500	3.5678	0.49284	0.742	0.403
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 30 kHz pip	1.1162	3.0838	0.13499	0.898	0.752
body composition	body length	-0.032993	0.032884	-0.18859	0.619	0.323
body composition	body weight (at time of DXA)	-0.48575	0.68192	-0.27709	0.688	0.481
body composition	bone area, whole body scan, head excluded	0.16895	0.11961	0.91844	0.428	0.168
body composition	bone mineral content of whole body scan, head excluded	0.0042084	0.0084666	0.38473	0.822	0.623
body composition	bone mineral content to body weight ratio	0.00013068	0.00043033	0.32367	0.895	0.763
body composition	bone mineral density of whole body scan, head excluded	-0.00042713	0.00040350	-0.44677	0.599	0.298
body composition	fat tissue mass of whole body scan, head excluded	-0.62889	0.42512	-1.1704	0.373	0.149
body composition	fat tissue mass to body weight ratio	-0.023717	0.014088	-1.0634	0.285	0.102
body composition	lean tissue mass of whole body scan, head excluded	0.70018	0.41668	1.1731	0.367	0.103
body composition	lean tissue mass to body weight ratio	0.020691	0.016461	1.0094	0.471	0.218
body composition	percent fat, whole body scan, head excluded	-2.2574	1.3634	-1.0927	0.300	0.108
body composition	ratio of soft-tissue attenuation coefficients	0.0025091	0.0015152	1.0939	0.296	0.108
body composition	tissue area	0.035976	0.16408	0.31253	0.945	0.828
body composition	total tissue mass, whole body scan, head excluded	0.078052	0.20867	-0.047803	0.848	0.711
clinical blood chemistry	alanine transaminase (plasma ALT)	20.390	20.623	1.1786	0.692	0.335
clinical blood chemistry	albumin (plasma Alb)	0.91766	0.41033	1.3593	0.236	0.0375
clinical blood chemistry	alkaline phosphatase (plasma ALP)	5.1223	2.5462	0.43176	0.213	0.0579
clinical blood chemistry	aspartate transaminase (plasma AST)	127.91	95.790	2.3410	0.521	0.198
clinical blood chemistry	aspartate transaminase to alanine transaminase ratio (plasma AST:ALT)	0.96622	0.63489	2.1071	0.524	0.145
clinical blood chemistry	blood urea nitrogen (BUN)	3.6667	1.2683	1.4086	0.0797	0.00903
clinical blood chemistry	calcium (plasma Ca)	-0.075000	0.097675	-0.18373	0.677	0.452
clinical blood chemistry	creatinine (plasma)	0.037987	0.026655	1.0542	0.402	0.172
clinical blood chemistry	glucose (plasma GLU, no fast)	11.917	14.392	0.75328	0.623	0.417
clinical blood chemistry	HDL cholesterol (plasma HDL)	-2.8429	3.3408	-0.93585	0.692	0.405
clinical blood chemistry	HDL cholesterol to total cholesterol ratio	0.017529	0.0081256	0.84813	0.274	0.0440
clinical blood chemistry	phosphorus (plasma phosphate)	0.36941	0.58519	0.49793	0.774	0.535
clinical blood chemistry	total bilirubin (plasma TBIL)	0.014167	0.0093382	0.91080	0.460	0.145
clinical blood chemistry	total cholesterol (plasma CHOL, no fast)	-6.8077	4.5410	-1.2729	0.428	0.150
clinical blood chemistry	total protein (plasma TP)	-0.42302	0.56394	-0.38932	0.703	0.462
clinical blood chemistry	triglyceride (plasma TG, no fast)	-18.236	9.1655	-0.75961	0.258	0.0612
EKG	duration of PQ interval	0.82875	1.2345	1.0248	0.924	0.624
EKG	duration of PR interval	0.51750	1.3798	0.61495	0.940	0.772
EKG	duration of QRS interval	-0.15500	0.32840	-0.56460	0.967	0.719
EKG	duration of QT interval	1.0462	1.6413	1.1681	0.914	0.639
EKG	duration of QTC interval, calculated by dividing QT interval by square root of preceding RR interval	1.1938	1.8786	1.2834	0.939	0.640
EKG	duration of RR interval	0.12250	1.1020	0.29646	0.970	0.930
EKG	duration of ST interval	1.2188	1.8199	1.4585	0.908	0.624
EKG	heart rate coefficient of variation (signal intensity)	0.11625	1.2397	0.19261	0.982	0.940
EKG	heart rate variability, mean of differences between sequential beats; beats per min	0.88875	9.1018	0.19671	0.983	0.938
EKG	heart rate, beats per min	-1.9000	9.4687	-0.37892	0.964	0.874
EKG	mean R amplitude, mean amplitude of signal measured from isoelectric line to peak of QRS	0.0017500	0.21897	-0.12841	0.999	0.995
EKG	mean SR amplitude, mean amplitude of signal measured from signal minimum line to peak of QRS	0.055535	0.21258	0.21851	0.942	0.837
EKG	number of signals	2.9500	4.8089	0.54813	0.917	0.650
EKG	proportion of number pairs of successive beat-to-beat intervals that exceed 50 ms	-1.7984	1.9298	-0.26766	0.874	0.522
EKG	QT dispersion, measured as inter-lead variability of QT intervals	1.5250	3.5059	0.47238	0.968	0.739
EKG	QTc dispersion, calculated as rate-corrected QT dispersion	2.3375	3.9640	0.60283	0.951	0.661
EKG	root mean square of successive differences of neighboring RR intervals	0.89237	2.2108	0.60525	0.947	0.756
glucose tolerance test	amount glucose injected	-1.9942	3.2527	-0.23098	0.880	0.650
glucose tolerance test	plasma glucose, 0min	12.362	19.005	0.99482	0.800	0.633
glucose tolerance test	plasma glucose, 15min	-6.8000	13.220	-0.092104	0.893	0.698
glucose tolerance test	plasma glucose, 30min	-29.15	18.353	-0.78282	0.674	0.358
glucose tolerance test	plasma glucose, 60min	-45.425	22.829	-1.6906	0.620	0.296
glucose tolerance test	plasma glucose, 120min	-27.088	8.5906	-1.8632	0.507	0.196
grip strength	body weight (at time of grip strength test)	-0.084250	0.52730	0.13239	0.934	0.875
grip strength	forelimb and hindlimb grip strength (mean of trials), average	-39.877	8.0740	-2.2901	0.00180	0.0000692
grip strength	forelimb and hindlimb grip strength (mean of trials), average normalized to bw	-1.8216	0.35973	-2.1839	0.00181	0.0000452
grip strength	forelimb and hindlimb grip strength by trial, trial1	-38.378	8.7798	-2.0600	0.00990	0.000267
grip strength	forelimb and hindlimb grip strength by trial, trial2	-40.441	9.5797	-2.2339	0.0144	0.000383
grip strength	forelimb and hindlimb grip strength by trial, trial3	-40.798	8.8351	-2.1534	0.00582	0.000148
grip strength	forelimb grip strength (mean of trials), average	-24.860	4.7693	-2.3106	0.00191	0.0000363
grip strength	forelimb grip strength (mean of trials), average normalized to bw	-1.1282	0.22170	-2.0138	0.00333	0.0000425
grip strength	forelimb grip strength by trial, trial1	-23.975	5.7627	-2.2705	0.0251	0.000408
grip strength	forelimb grip strength by trial, trial2	-23.938	4.9192	-2.0978	0.00613	0.0000823
grip strength	forelimb grip strength by trial, trial3	-27.1	5.0123	-2.2705	0.00244	0.0000198
heart weight	heart weight, normalized to body weight	-0.10555	0.13472	-0.85323	0.647	0.443
heart weight	heart weight, weight	-1.0172	3.7610	-0.50512	0.886	0.790
hematology	basophil differential (percent of total WBC)	-0.026606	0.042741	-0.38251	0.843	0.541
hematology	calculated hemoglobin (cHGB)	-0.22589	0.12765	-0.93553	0.319	0.0920
hematology	eosinophil differential (percent of total WBC)	0.13615	0.25427	0.48695	0.870	0.598
hematology	hematocrit (HCT)	-0.21070	0.48347	-0.57560	0.841	0.668
hematology	hemoglobin concentration distribution width (HDW)	-0.020164	0.017511	-0.57003	0.573	0.264
hematology	large unstained cells (percent of total WBC)	0.062862	0.15054	0.42312	0.875	0.681
hematology	lymphocyte differential (percent of total WBC)	4.0667	1.8968	1.3343	0.205	0.0445
hematology	mean corpuscular hemoglobin (CHr)	-0.10030	0.056451	-0.80782	0.270	0.0916
hematology	mean platelet volume (MPV)	-0.23434	0.082247	-1.3593	0.0558	0.0103
hematology	mean RBC corpuscular hemoglobin (MCH)	-0.19400	0.056009	-0.69375	0.0550	0.00260
hematology	mean RBC corpuscular hemoglobin concentration (MCHC)	-0.46620	0.12930	-0.85536	0.0584	0.00188
hematology	mean RBC corpuscular volume (MCV)	-0.043709	0.20973	-0.075242	0.931	0.837
hematology	measured hemoglobin (mHGB)	-0.27021	0.14391	-0.83308	0.316	0.0751
hematology	monocyte differential (percent of total WBC)	-0.52566	0.16639	-1.1563	0.123	0.00516
hematology	neutrophil differential (percent of total WBC)	-3.9583	1.7401	-1.4733	0.176	0.0341
hematology	platelet count (PLT; units per volume x 10³)	74.000	34.453	0.99769	0.319	0.0442
hematology	RBC corpuscular distribution width (RDW)	-0.0096070	0.095868	-0.045928	0.967	0.921
hematology	RBC corpuscular hemoglobin concentration mean (CHCM)	-0.41672	0.13594	-1.1403	0.0522	0.00637
hematology	red blood cell count (RBC; per volume x 10⁶)	0.048487	0.091343	-0.12621	0.790	0.601
hematology	reticulocyte count (Retic; units per volume x 10⁹)	24.236	9.4211	1.0548	0.241	0.0186
hematology	reticulocyte differential (percent of total RBC)	0.20252	0.097391	1.0068	0.345	0.0514
hematology	white blood cell count (WBC; units per volume x 10³)	-0.99455	0.46981	-0.52315	0.159	0.0470
holeboard	number of hole pokes by individual hole number, 20 min test, 1	1.1996	0.73244	1.1076	0.616	0.112
holeboard	number of hole pokes by individual hole number, 20 min test, 2	0.73684	0.56062	1.3476	0.729	0.199
holeboard	number of hole pokes by individual hole number, 20 min test, 3	0.41447	0.56473	0.76471	0.864	0.469
holeboard	number of hole pokes by individual hole number, 20 min test, 4	0.91447	0.67277	0.97418	0.654	0.185
holeboard	number of hole pokes by individual hole number, 20 min test, 5	0.38816	0.49165	0.72901	0.846	0.436
holeboard	number of hole pokes by individual hole number, 20 min test, 6	-0.17105	0.31025	-0.45180	0.930	0.586
holeboard	number of hole pokes by individual hole number, 20 min test, 7	0.48462	0.32365	1.2306	0.737	0.145
holeboard	number of hole pokes by individual hole number, 20 min test, 8	0.73026	0.57295	1.2873	0.752	0.213
holeboard	number of hole pokes by individual hole number, 20 min test, 9	0.013158	0.59932	0.13213	0.994	0.983
holeboard	number of hole pokes by individual hole number, 20 min test, 10	0.16447	0.34956	0.48140	0.942	0.642
holeboard	number of hole pokes by individual hole number, 20 min test, 11	0.089509	0.20448	0.26838	0.926	0.665
holeboard	number of hole pokes by individual hole number, 20 min test, 12	0.33878	0.44060	0.64825	0.825	0.448
holeboard	number of hole pokes by individual hole number, 20 min test, 13	0.56336	0.75322	0.63581	0.796	0.461
holeboard	number of hole pokes by individual hole number, 20 min test, 14	-0.33800	0.63197	-0.44620	0.868	0.597
holeboard	number of hole pokes by individual hole number, 20 min test, 15	-0.46526	0.30282	-0.65660	0.624	0.135
holeboard	number of hole pokes by individual hole number, 20 min test, 16	0.012751	0.81733	0.038807	0.997	0.988
holeboard	total number of hole pokes, 20 min test	5.0461	3.4770	0.77201	0.434	0.157
light / dark	fecal boli count, 20 min test	0.70000	0.75020	0.80519	0.744	0.358
light / dark	latency to enter dark zone, 20 min test	68.312	71.348	1.1013	0.738	0.346
light / dark	number of transitions between light and dark zones, 20 min test	-13.505	6.4763	-1.2585	0.259	0.0454
light / dark	percentage of total time in dark zone, 20 min test	1.4714	5.9721	0.40124	0.935	0.807
light / dark	percentage of total time in light zone, 20 min test	-1.4714	5.9721	-0.40711	0.936	0.807
light / dark	time mobile in dark zone, 20 min test	-27.839	14.928	-1.6029	0.292	0.0717
light / dark	time mobile in light zone, 20 min test	-9.1638	10.170	-0.90050	0.638	0.374
light / dark	time spent in dark zone, 20 min test	18.945	73.421	0.49087	0.940	0.798
light / dark	time spent in light zone, 20 min test	-18.945	73.421	-0.49087	0.940	0.798
open field	average speed in center of arena, 20 min test	-0.13249	0.51990	-0.34150	0.937	0.801
open field	average speed in periphery of arena, 20 min test	-0.022790	0.15471	-0.60488	0.937	0.884
open field	distance traveled habituation ratio, 20 min test	11.643	6.3175	0.94655	0.338	0.0752
open field	distance traveled in center of arena, 20 min test	-160.36	88.800	-1.3643	0.263	0.0810
open field	distance traveled in periphery of arena, 20 min test	24.446	162.92	-0.34008	0.947	0.882
open field	distance traveled slope, 20 min test	10.166	5.9532	0.90735	0.373	0.0980
open field	distance traveled, 20 min test, 1st 5min	-85.508	70.461	-1.0138	0.482	0.235
open field	distance traveled, 20 min test, 2nd 5min	-42.556	61.960	-0.99164	0.719	0.498
open field	distance traveled, 20 min test, 3rd 5min	-31.236	52.362	-0.78993	0.766	0.555
open field	distance traveled, 20 min test, 4th 5min	40.099	52.543	-0.0033565	0.687	0.451
open field	number of clockwise revolution episodes, 20 min test	-1.3304	1.6223	-1.2475	0.754	0.419
open field	number of counter-clockwise revolution episodes, 20 min test	0.26974	1.7161	-0.29209	0.951	0.876
open field	number of fecal boli, 20 min test	0.57936	0.95057	0.67834	0.793	0.547
open field	number of rears in 5 min bins, 20 min test, 1st 5min	-4.1243	2.7684	-1.3307	0.391	0.147
open field	number of rears in 5 min bins, 20 min test, 2nd 5min	-1.7697	2.8907	-0.80469	0.768	0.545
open field	number of rears in 5 min bins, 20 min test, 3rd 5min	-0.57895	3.0097	-0.44008	0.927	0.849
open field	number of rears in 5 min bins, 20 min test, 4th 5min	-1.4119	3.1256	-0.63088	0.824	0.655
open field	percentage of total time in center of arena, 20 min test	-2.8326	2.6757	-0.88132	0.614	0.298
open field	percentage of total time in center of arena, slope, 20 min test	-0.78113	1.3395	-0.31882	0.869	0.564
open field	percentage of total time in center, habituation ratio, 20 min test	-0.55913	1.4284	-0.17203	0.913	0.698
open field	percentage of total time in corners of arena, 20 min test	4.7280	3.1685	1.1410	0.446	0.146
open field	percentage of total time in corners, habituation ratio, 20 min test	1.5299	1.9647	0.40776	0.852	0.442
open field	percentage of total time in corners, slope, 20 min test	1.0647	1.8295	0.21443	0.902	0.565
open field	permanence time in center of arena, 20 min test	-33.988	32.108	-0.88132	0.615	0.298
open field	permanence time in corners of arena, 20 min test	56.748	38.023	1.1410	0.447	0.146
open field	permanence time in periphery of arena, 20 min test	33.978	32.112	0.87934	0.614	0.298
open field	total distance traveled, 20 min test	-138.09	213.77	-0.88926	0.718	0.523
open field	total number of rears, 20 min test	-7.7105	10.502	-0.88926	0.701	0.469
open field	whole arena average speed, 20 min test	-0.11565	0.17836	-0.89126	0.717	0.522
open field	whole arena resting time, 20 min test	-6.5842	19.594	0.38019	0.845	0.739
open field	whole arena time spent mobile, 20 min test	6.4421	19.586	-0.24753	0.854	0.745
open field	whole arena time spent vertical, 20 min test	-12.882	10.340	-1.1156	0.531	0.222
SHIRPA	locomotor activity (number of squares in the arena the mouse moves into with all four paws in first 30 s of test)	-3.325	1.6810	-1.2427	0.286	0.0606
startle / PPI	average baseline movement during background noise	-2.5971	3.0044	-1.6583	0.852	0.398
startle / PPI	average of each corrected maximum percent pre-pulse inhibition value	0.022892	0.097610	0.096125	0.930	0.817
startle / PPI	average of each corrected percent pre-pulse inhibition value	0.021759	0.091080	0.13861	0.923	0.814
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-3.8836	11.036	-0.37350	0.959	0.729
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-2.2492	11.175	-0.28619	0.951	0.843
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	1.7386	8.1967	0.075031	0.937	0.834
startle / PPI	average startle response to full pulse (120 dB)	-106.32	47.207	-1.5022	0.149	0.0357
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-103.19	48.048	-1.4093	0.164	0.0442
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-97.374	41.654	-1.4894	0.124	0.0299
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-69.437	31.750	-1.2844	0.162	0.0408
startle / PPI	average startle response to pre-pulse, 74dB sound pressure level	1.2323	1.5707	0.81360	0.843	0.442
startle / PPI	average startle response to pre-pulse, 78dB sound pressure level	1.1213	2.0442	0.69441	0.913	0.590
startle / PPI	average startle response to pre-pulse, 82dB sound pressure level	-0.22185	2.2398	-0.29642	0.982	0.922
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-0.033649	0.11574	-0.25132	0.965	0.774
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-0.0046196	0.12363	-0.13719	0.996	0.971
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	0.037577	0.092951	0.14632	0.864	0.690
startle / PPI	corrected average startle response to full pulse (120 dB) minus average baseline movement during background noise	-104.41	45.647	-1.4851	0.142	0.0332
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 74dB sound pressure level	-104.50	47.914	-1.4207	0.156	0.0413
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 78dB sound pressure level	-98.271	41.589	-1.4979	0.118	0.0284
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 82dB sound pressure level	-69.197	31.612	-1.2409	0.158	0.0406
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-0.052723	0.12922	-0.44357	0.943	0.688
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-0.021059	0.12883	-0.25508	0.952	0.872
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	0.060744	0.096265	0.26233	0.755	0.535
startle / PPI	corrected maximum startle response to full pulse (120 dB) minus maximum baseline movement during background noise	-352.70	166.34	-1.4055	0.175	0.0467
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 74dB sound pressure level	-334.65	166.33	-1.3071	0.195	0.0579
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 78dB sound pressure level	-341.02	151.28	-1.4562	0.140	0.0356
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 82dB sound pressure level	-257.58	117.62	-1.2624	0.156	0.0405
startle / PPI	maximum baseline movement during background noise	-6.8340	6.7075	-1.7414	0.781	0.320
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-5.4098	12.329	-0.50155	0.948	0.666
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-3.2602	12.041	-0.35852	0.917	0.790
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	4.7096	8.6931	0.29935	0.804	0.594
startle / PPI	maximum startle response to full pulse (120 dB)	-357.98	169.60	-1.4169	0.177	0.0476
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-332.80	166.63	-1.3071	0.197	0.0596
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-340.08	150.97	-1.4603	0.140	0.0357
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-259.15	116.65	-1.3071	0.150	0.0380
startle / PPI	maximum startle response to pre-pulse, 74dB sound pressure level	1.9732	4.1142	0.66441	0.917	0.637
startle / PPI	maximum startle response to pre-pulse, 78dB sound pressure level	1.8259	4.6491	0.54006	0.943	0.699
startle / PPI	maximum startle response to pre-pulse, 82dB sound pressure level	-1.1764	4.8674	-0.41591	0.934	0.811

MULTIPLE (CATEGORICAL) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

Procedure	JaxKOMP-EAP Trait	Sex	Trait Effect	P-value
eye morphology	anterior chamber depth	females	1.0 %	1.0
eye morphology	anterior chamber depth	males	0.0 %	1.0
eye morphology	anterior chamber depth	both	1.0 %	1.0
eye morphology	bulging eye	females	1.0 %	1.00
eye morphology	bulging eye	males	0.0 %	1.0
eye morphology	bulging eye	both	1.0 %	1.0
eye morphology	cornea	females	4.0 %	1.0
eye morphology	cornea	males	2.0 %	1.0
eye morphology	cornea	both	3.0 %	1.0
eye morphology	cornea opacity	females	5.0 %	1.0
eye morphology	cornea opacity	males	1.0 %	1.0
eye morphology	cornea opacity	both	3.0 %	1.0
eye morphology	cornea vascularization	females	3.0 %	1.0
eye morphology	cornea vascularization	males	1.0 %	1.0
eye morphology	cornea vascularization	both	2.0 %	1.0
eye morphology	corneal deposits	females	2.0 %	1.0
eye morphology	corneal deposits	males	1.0 %	1.0
eye morphology	corneal deposits	both	1.0 %	1.0
eye morphology	corneal mineralization	females	2.0 %	1.0
eye morphology	corneal mineralization	males	1.0 %	1.0
eye morphology	corneal mineralization	both	1.0 %	1.00
eye morphology	corneal scleralization	females	3.0 %	1.0
eye morphology	corneal scleralization	males	1.0 %	1.0
eye morphology	corneal scleralization	both	2.0 %	1.0
eye morphology	corneal ulcer	females	1.0 %	1.0
eye morphology	corneal ulcer	males	1.0 %	1.0
eye morphology	corneal ulcer	both	1.0 %	1.00
eye morphology	eye closure	females	1.0 %	1.0
eye morphology	eye closure	males	0.0 %	1.0
eye morphology	eye closure	both	1.0 %	1.0
eye morphology	eye hemorrhage or blood presence	females	2.0 %	1.0
eye morphology	eye hemorrhage or blood presence	males	1.0 %	1.0
eye morphology	eye hemorrhage or blood presence	both	1.0 %	1.0
eye morphology	eyelid morphology	females	1.0 %	1.0
eye morphology	eyelid morphology	males	0.0 %	1.0
eye morphology	eyelid morphology	both	1.0 %	1.0
eye morphology	eyes (present, absent)	females	1.0 %	1.0
eye morphology	eyes (present, absent)	males	0.0 %	1.0
eye morphology	eyes (present, absent)	both	0.0 %	1.0
eye morphology	fusion between cornea and lens	females	4.0 %	1.0
eye morphology	fusion between cornea and lens	males	2.0 %	1.0
eye morphology	fusion between cornea and lens	both	3.0 %	1.0
eye morphology	iris pigmentation	females	2.0 %	1.0
eye morphology	iris pigmentation	males	1.0 %	1.0
eye morphology	iris pigmentation	both	2.0 %	1.0
eye morphology	iris transillumination	females	2.0 %	1.0
eye morphology	iris transillumination	males	1.0 %	1.0
eye morphology	iris transillumination	both	1.0 %	1.0
eye morphology	irispupil	females	4.0 %	1.0
eye morphology	irispupil	males	3.0 %	1.0
eye morphology	irispupil	both	3.0 %	1.0
eye morphology	lacrimation	females	3.0 %	1.0
eye morphology	lacrimation	males	2.0 %	1.0
eye morphology	lacrimation	both	3.0 %	1.00
eye morphology	lens	females	10.0 %	1.0
eye morphology	lens	males	8.0 %	1.0
eye morphology	lens	both	9.0 %	1.0
eye morphology	lens opacity	females	9.0 %	1.0
eye morphology	lens opacity	males	23.0 %	0.205
eye morphology	lens opacity	both	10.0 %	0.455
eye morphology	narrow eye opening	females	2.0 %	1.0
eye morphology	narrow eye opening	males	1.0 %	1.0
eye morphology	narrow eye opening	both	1.0 %	1.00
eye morphology	optic disc	females	4.0 %	1.0
eye morphology	optic disc	males	2.0 %	1.00
eye morphology	optic disc	both	3.0 %	1.0
eye morphology	persistence of hyaloid vascular system	females	14.0 %	1.0
eye morphology	persistence of hyaloid vascular system	males	23.0 %	0.184
eye morphology	persistence of hyaloid vascular system	both	8.0 %	0.542
eye morphology	pupil dilation	females	2.0 %	1.0
eye morphology	pupil dilation	males	1.0 %	1.00
eye morphology	pupil dilation	both	2.0 %	1.0
eye morphology	pupil light response	females	2.0 %	1.0
eye morphology	pupil light response	males	1.0 %	1.0
eye morphology	pupil light response	both	2.0 %	1.0
eye morphology	pupil position	females	4.0 %	1.0
eye morphology	pupil position	males	3.0 %	1.0
eye morphology	pupil position	both	4.0 %	1.0
eye morphology	pupil shape	females	3.0 %	1.0
eye morphology	pupil shape	males	2.0 %	1.0
eye morphology	pupil shape	both	3.0 %	1.0
eye morphology	retina	females	10.0 %	1.0
eye morphology	retina	males	16.0 %	1.0
eye morphology	retina	both	13.0 %	1.0
eye morphology	retinal blood vessels	females	4.0 %	1.0
eye morphology	retinal blood vessels	males	2.0 %	1.0
eye morphology	retinal blood vessels	both	3.0 %	1.0
eye morphology	retinal blood vessels pattern	females	5.0 %	1.0
eye morphology	retinal blood vessels pattern	males	2.0 %	1.0
eye morphology	retinal blood vessels pattern	both	4.0 %	1.0
eye morphology	retinal blood vessels structure	females	4.0 %	1.0
eye morphology	retinal blood vessels structure	males	2.0 %	1.0
eye morphology	retinal blood vessels structure	both	3.0 %	1.0
eye morphology	retinal pigmentation	females	38.0 %	0.0780
eye morphology	retinal pigmentation	males	20.0 %	0.441
eye morphology	retinal pigmentation	both	25.0 %	0.0959
eye morphology	retinal structure	females	4.0 %	1.0
eye morphology	retinal structure	males	2.0 %	1.0
eye morphology	retinal structure	both	3.0 %	1.0
eye morphology	synechia	females	4.0 %	1.0
eye morphology	synechia	males	2.0 %	1.00
eye morphology	synechia	both	3.0 %	1.00
eye morphology	vitreous	females	4.0 %	1.0
eye morphology	vitreous	males	2.0 %	1.0
eye morphology	vitreous	both	3.0 %	1.0
SHIRPA	activity body position	females	1.0 %	1.0
SHIRPA	activity body position	males	2.0 %	1.0
SHIRPA	activity body position	both	1.0 %	1.00
SHIRPA	aggression	females	0.0 %	1.00
SHIRPA	aggression	males	1.0 %	1.0
SHIRPA	aggression	both	1.0 %	1.0
SHIRPA	body length	females	0.0 %	1.0
SHIRPA	body length	males	0.0 %	1.00
SHIRPA	body length	both	0.0 %	1.00
SHIRPA	body position	females	0.0 %	1.0
SHIRPA	body position	males	1.0 %	1.0
SHIRPA	body position	both	0.0 %	1.0
SHIRPA	body thickness	females	1.0 %	1.0
SHIRPA	body thickness	males	0.0 %	1.0
SHIRPA	body thickness	both	0.0 %	1.0
SHIRPA	coat color abdomen	females	3.0 %	1.00
SHIRPA	coat color abdomen	males	4.0 %	1.0
SHIRPA	coat color abdomen	both	4.0 %	1.0
SHIRPA	coat color back	females	0.0 %	1.0
SHIRPA	coat color back	males	0.0 %	1.00
SHIRPA	coat color back	both	0.0 %	1.00
SHIRPA	coat color head	females	0.0 %	1.0
SHIRPA	coat color head	males	0.0 %	1.00
SHIRPA	coat color head	both	0.0 %	1.0
SHIRPA	coat color pattern abdomen	females	1.0 %	1.0
SHIRPA	coat color pattern abdomen	males	1.0 %	1.0
SHIRPA	coat color pattern abdomen	both	1.0 %	1.0
SHIRPA	coat color pattern back	females	0.0 %	1.0
SHIRPA	coat color pattern back	males	0.0 %	1.00
SHIRPA	coat color pattern back	both	0.0 %	1.0
SHIRPA	coat color pattern head	females	0.0 %	1.0
SHIRPA	coat color pattern head	males	0.0 %	1.0
SHIRPA	coat color pattern head	both	0.0 %	1.00
SHIRPA	coat hair abdomen texture appearance	females	2.0 %	1.0
SHIRPA	coat hair abdomen texture appearance	males	2.0 %	1.0
SHIRPA	coat hair abdomen texture appearance	both	2.0 %	1.0
SHIRPA	coat hair back texture appearance	females	0.0 %	1.0
SHIRPA	coat hair back texture appearance	males	0.0 %	1.0
SHIRPA	coat hair back texture appearance	both	0.0 %	1.0
SHIRPA	coat hair distribution abdomen	females	0.0 %	1.0
SHIRPA	coat hair distribution abdomen	males	1.0 %	1.00
SHIRPA	coat hair distribution abdomen	both	1.0 %	1.00
SHIRPA	coat hair distribution back	females	0.0 %	1.0
SHIRPA	coat hair distribution back	males	0.0 %	1.0
SHIRPA	coat hair distribution back	both	0.0 %	1.0
SHIRPA	coat hair distribution head	females	1.0 %	1.00
SHIRPA	coat hair distribution head	males	1.0 %	1.0
SHIRPA	coat hair distribution head	both	1.0 %	1.0
SHIRPA	coat hair head texture appearance	females	0.0 %	1.00
SHIRPA	coat hair head texture appearance	males	0.0 %	1.0
SHIRPA	coat hair head texture appearance	both	0.0 %	1.0
SHIRPA	contact righting	females	5.0 %	1.0
SHIRPA	contact righting	males	5.0 %	1.00
SHIRPA	contact righting	both	5.0 %	1.00
SHIRPA	ear morphology	females	0.0 %	1.0
SHIRPA	ear morphology	males	0.0 %	1.0
SHIRPA	ear morphology	both	0.0 %	1.0
SHIRPA	fat distribution	females	0.0 %	1.0
SHIRPA	fat distribution	males	0.0 %	1.0
SHIRPA	fat distribution	both	0.0 %	1.00
SHIRPA	forelimb digit number	females	0.0 %	1.00
SHIRPA	forelimb digit number	males	0.0 %	1.0
SHIRPA	forelimb digit number	both	0.0 %	1.00
SHIRPA	forelimb digit position	females	0.0 %	1.0
SHIRPA	forelimb digit position	males	0.0 %	1.0
SHIRPA	forelimb digit position	both	0.0 %	1.0
SHIRPA	forelimb digit shape	females	0.0 %	1.0
SHIRPA	forelimb digit shape	males	0.0 %	1.0
SHIRPA	forelimb digit shape	both	0.0 %	1.0
SHIRPA	forelimb digit size	females	0.0 %	1.0
SHIRPA	forelimb digit size	males	0.0 %	1.0
SHIRPA	forelimb digit size	both	0.0 %	1.0
SHIRPA	forelimb footpads	females	0.0 %	1.0
SHIRPA	forelimb footpads	males	0.0 %	1.0
SHIRPA	forelimb footpads	both	0.0 %	1.0
SHIRPA	forelimb nail length	females	0.0 %	1.0
SHIRPA	forelimb nail length	males	0.0 %	1.0
SHIRPA	forelimb nail length	both	0.0 %	1.0
SHIRPA	forelimb nail number	females	0.0 %	1.0
SHIRPA	forelimb nail number	males	0.0 %	1.0
SHIRPA	forelimb nail number	both	0.0 %	1.0
SHIRPA	forelimb nail position	females	0.0 %	1.0
SHIRPA	forelimb nail position	males	0.0 %	1.0
SHIRPA	forelimb nail position	both	0.0 %	1.0
SHIRPA	forelimb nail shape	females	0.0 %	1.0
SHIRPA	forelimb nail shape	males	0.0 %	1.0
SHIRPA	forelimb nail shape	both	0.0 %	1.0
SHIRPA	forelimbs position	females	0.0 %	1.0
SHIRPA	forelimbs position	males	0.0 %	1.0
SHIRPA	forelimbs position	both	0.0 %	1.0
SHIRPA	forelimbs shape	females	0.0 %	1.0
SHIRPA	forelimbs shape	males	0.0 %	1.0
SHIRPA	forelimbs shape	both	0.0 %	1.0
SHIRPA	forelimbs size	females	0.0 %	1.0
SHIRPA	forelimbs size	males	0.0 %	1.0
SHIRPA	forelimbs size	both	0.0 %	1.0
SHIRPA	forepaw position	females	0.0 %	1.0
SHIRPA	forepaw position	males	0.0 %	1.0
SHIRPA	forepaw position	both	0.0 %	1.0
SHIRPA	forepaw shape	females	0.0 %	1.0
SHIRPA	forepaw shape	males	0.0 %	1.0
SHIRPA	forepaw shape	both	0.0 %	1.0
SHIRPA	forepaw size	females	0.0 %	1.0
SHIRPA	forepaw size	males	0.0 %	1.0
SHIRPA	forepaw size	both	0.0 %	1.0
SHIRPA	gait (fluidity)	females	0.0 %	1.0
SHIRPA	gait (fluidity)	males	0.0 %	1.00
SHIRPA	gait (fluidity)	both	0.0 %	1.00
SHIRPA	genitalia morphology	females	0.0 %	1.00
SHIRPA	genitalia morphology	males	0.0 %	1.0
SHIRPA	genitalia morphology	both	0.0 %	1.00
SHIRPA	genitalia presence	females	0.0 %	1.0
SHIRPA	genitalia presence	males	0.0 %	1.0
SHIRPA	genitalia presence	both	0.0 %	1.0
SHIRPA	genitalia size	females	0.0 %	1.0
SHIRPA	genitalia size	males	0.0 %	1.0
SHIRPA	genitalia size	both	0.0 %	1.0
SHIRPA	head bobbing	females	0.0 %	1.0
SHIRPA	head bobbing	males	0.0 %	1.0
SHIRPA	head bobbing	both	0.0 %	1.0
SHIRPA	head morphology	females	0.0 %	1.0
SHIRPA	head morphology	males	0.0 %	1.00
SHIRPA	head morphology	both	0.0 %	1.0
SHIRPA	head size	females	0.0 %	1.0
SHIRPA	head size	males	0.0 %	1.0
SHIRPA	head size	both	0.0 %	1.00
SHIRPA	hindlimb digit number	females	1.0 %	1.00
SHIRPA	hindlimb digit number	males	0.0 %	1.0
SHIRPA	hindlimb digit number	both	0.0 %	1.00
SHIRPA	hindlimb digit position	females	0.0 %	1.0
SHIRPA	hindlimb digit position	males	0.0 %	1.0
SHIRPA	hindlimb digit position	both	0.0 %	1.0
SHIRPA	hindlimb digit shape	females	0.0 %	1.0
SHIRPA	hindlimb digit shape	males	0.0 %	1.0
SHIRPA	hindlimb digit shape	both	0.0 %	1.0
SHIRPA	hindlimb digit size	females	0.0 %	1.00
SHIRPA	hindlimb digit size	males	0.0 %	1.0
SHIRPA	hindlimb digit size	both	0.0 %	1.00
SHIRPA	hindlimb nail length	females	0.0 %	1.0
SHIRPA	hindlimb nail length	males	0.0 %	1.0
SHIRPA	hindlimb nail length	both	0.0 %	1.00
SHIRPA	hindlimb nail number	females	0.0 %	1.0
SHIRPA	hindlimb nail number	males	1.0 %	1.0
SHIRPA	hindlimb nail number	both	0.0 %	1.00
SHIRPA	hindlimb nail position	females	0.0 %	1.0
SHIRPA	hindlimb nail position	males	0.0 %	1.0
SHIRPA	hindlimb nail position	both	0.0 %	1.0
SHIRPA	hindlimb nail shape	females	0.0 %	1.0
SHIRPA	hindlimb nail shape	males	0.0 %	1.0
SHIRPA	hindlimb nail shape	both	0.0 %	1.0
SHIRPA	hindlimbs footpads	females	0.0 %	1.0
SHIRPA	hindlimbs footpads	males	0.0 %	1.0
SHIRPA	hindlimbs footpads	both	0.0 %	1.0
SHIRPA	hindlimbs position	females	0.0 %	1.0
SHIRPA	hindlimbs position	males	0.0 %	1.0
SHIRPA	hindlimbs position	both	0.0 %	1.0
SHIRPA	hindlimbs shape	females	0.0 %	1.0
SHIRPA	hindlimbs shape	males	0.0 %	1.0
SHIRPA	hindlimbs shape	both	0.0 %	1.0
SHIRPA	hindlimbs size	females	0.0 %	1.0
SHIRPA	hindlimbs size	males	0.0 %	1.0
SHIRPA	hindlimbs size	both	0.0 %	1.0
SHIRPA	hindpaw position	females	0.0 %	1.0
SHIRPA	hindpaw position	males	0.0 %	1.0
SHIRPA	hindpaw position	both	0.0 %	1.0
SHIRPA	hindpaw shape	females	0.0 %	1.0
SHIRPA	hindpaw shape	males	0.0 %	1.0
SHIRPA	hindpaw shape	both	0.0 %	1.0
SHIRPA	hindpaw size	females	0.0 %	1.0
SHIRPA	hindpaw size	males	0.0 %	1.0
SHIRPA	hindpaw size	both	0.0 %	1.0
SHIRPA	limb grasp	females	9.0 %	1.00
SHIRPA	limb grasp	males	6.0 %	1.0
SHIRPA	limb grasp	both	7.0 %	0.624
SHIRPA	lower lip morphology	females	0.0 %	1.0
SHIRPA	lower lip morphology	males	0.0 %	1.0
SHIRPA	lower lip morphology	both	0.0 %	1.0
SHIRPA	lower teeth appearance	females	0.0 %	1.0
SHIRPA	lower teeth appearance	males	0.0 %	1.00
SHIRPA	lower teeth appearance	both	0.0 %	1.00
SHIRPA	mouth morphology	females	0.0 %	1.0
SHIRPA	mouth morphology	males	0.0 %	1.00
SHIRPA	mouth morphology	both	0.0 %	1.00
SHIRPA	salivation	females	0.0 %	1.0
SHIRPA	salivation	males	0.0 %	1.0
SHIRPA	salivation	both	0.0 %	1.0
SHIRPA	skin color back paws	females	0.0 %	1.0
SHIRPA	skin color back paws	males	0.0 %	1.0
SHIRPA	skin color back paws	both	0.0 %	1.0
SHIRPA	skin color ear	females	0.0 %	1.0
SHIRPA	skin color ear	males	0.0 %	1.0
SHIRPA	skin color ear	both	0.0 %	1.0
SHIRPA	skin color front paws	females	0.0 %	1.0
SHIRPA	skin color front paws	males	0.0 %	1.0
SHIRPA	skin color front paws	both	0.0 %	1.0
SHIRPA	skin color snout	females	0.0 %	1.0
SHIRPA	skin color snout	males	0.0 %	1.0
SHIRPA	skin color snout	both	0.0 %	1.0
SHIRPA	skin color tail	females	0.0 %	1.0
SHIRPA	skin color tail	males	0.0 %	1.0
SHIRPA	skin color tail	both	0.0 %	1.0
SHIRPA	skin color whole body	females	0.0 %	1.0
SHIRPA	skin color whole body	males	0.0 %	1.0
SHIRPA	skin color whole body	both	0.0 %	1.0
SHIRPA	skin texture back paw	females	0.0 %	1.0
SHIRPA	skin texture back paw	males	0.0 %	1.0
SHIRPA	skin texture back paw	both	0.0 %	1.0
SHIRPA	skin texture ear	females	0.0 %	1.0
SHIRPA	skin texture ear	males	0.0 %	1.0
SHIRPA	skin texture ear	both	0.0 %	1.0
SHIRPA	skin texture front paws	females	0.0 %	1.0
SHIRPA	skin texture front paws	males	0.0 %	1.0
SHIRPA	skin texture front paws	both	0.0 %	1.0
SHIRPA	skin texture snout	females	0.0 %	1.0
SHIRPA	skin texture snout	males	0.0 %	1.0
SHIRPA	skin texture snout	both	0.0 %	1.0
SHIRPA	skin texture tail	females	0.0 %	1.0
SHIRPA	skin texture tail	males	0.0 %	1.0
SHIRPA	skin texture tail	both	0.0 %	1.0
SHIRPA	skin texture whole body	females	0.0 %	1.0
SHIRPA	skin texture whole body	males	0.0 %	1.00
SHIRPA	skin texture whole body	both	0.0 %	1.00
SHIRPA	snout size	females	0.0 %	1.0
SHIRPA	snout size	males	1.0 %	1.0
SHIRPA	snout size	both	0.0 %	1.0
SHIRPA	startle response	females	0.0 %	1.00
SHIRPA	startle response	males	0.0 %	1.00
SHIRPA	startle response	both	0.0 %	1.00
SHIRPA	tail curvature	females	0.0 %	1.00
SHIRPA	tail curvature	males	0.0 %	1.0
SHIRPA	tail curvature	both	0.0 %	1.0
SHIRPA	tail elevation	females	12.0 %	0.0740
SHIRPA	tail elevation	males	11.0 %	0.142
SHIRPA	tail elevation	both	11.0 %	0.0329
SHIRPA	tail length	females	0.0 %	1.0
SHIRPA	tail length	males	0.0 %	1.0
SHIRPA	tail length	both	0.0 %	1.00
SHIRPA	tail morphology	females	0.0 %	1.00
SHIRPA	tail morphology	males	0.0 %	1.0
SHIRPA	tail morphology	both	0.0 %	1.00
SHIRPA	tail presence	females	0.0 %	1.0
SHIRPA	tail presence	males	0.0 %	1.0
SHIRPA	tail presence	both	0.0 %	1.0
SHIRPA	tail shape	females	0.0 %	1.0
SHIRPA	tail shape	males	0.0 %	1.0
SHIRPA	tail shape	both	0.0 %	1.00
SHIRPA	tail thickness	females	0.0 %	1.0
SHIRPA	tail thickness	males	0.0 %	1.0
SHIRPA	tail thickness	both	0.0 %	1.0
SHIRPA	teeth presence	females	0.0 %	1.0
SHIRPA	teeth presence	males	0.0 %	1.00
SHIRPA	teeth presence	both	0.0 %	1.00
SHIRPA	transfer arousal	females	1.0 %	1.0
SHIRPA	transfer arousal	males	2.0 %	1.00
SHIRPA	transfer arousal	both	1.0 %	1.0
SHIRPA	tremor	females	0.0 %	1.0
SHIRPA	tremor	males	0.0 %	1.0
SHIRPA	tremor	both	0.0 %	1.00
SHIRPA	trunk curl	females	0.0 %	1.00
SHIRPA	trunk curl	males	0.0 %	1.0
SHIRPA	trunk curl	both	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	females	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	males	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	both	0.0 %	1.00
SHIRPA	upper lip morphology	females	0.0 %	1.0
SHIRPA	upper lip morphology	males	0.0 %	1.0
SHIRPA	upper lip morphology	both	0.0 %	1.0
SHIRPA	upper teeth appearance	females	0.0 %	1.0
SHIRPA	upper teeth appearance	males	0.0 %	1.0
SHIRPA	upper teeth appearance	both	0.0 %	1.00
SHIRPA	vibrissae appearance	females	2.0 %	1.0
SHIRPA	vibrissae appearance	males	1.0 %	1.0
SHIRPA	vibrissae appearance	both	1.0 %	1.0
SHIRPA	vibrissae presence	females	2.0 %	1.00
SHIRPA	vibrissae presence	males	1.0 %	1.0
SHIRPA	vibrissae presence	both	2.0 %	1.0
SHIRPA	vocalization	females	2.0 %	1.00
SHIRPA	vocalization	males	2.0 %	1.0
SHIRPA	vocalization	both	2.0 %	1.00

GENOTYPE CORRELATION PLOT

Correlate Fars2^em1(IMPC)J/Mmjax -/+ with genotype: