MPD: JaxKOMP-EAP genotype: Ahsa1<sup>em1(IMPC)J</sup> -/-

JaxKOMP-EAP effect sizes: Ahsa1^em1(IMPC)J -/- Gene Ahsa1

MULTIPLE (NUMERIC) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

Procedure	JaxKOMP-EAP Trait	Trait Effect	Trait Effect SE	Trait Effect RankZ	Adjusted p-value	Unadjusted p-value
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 6 kHz pip	-1.8894	2.1325	-0.79728	0.802	0.416
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 12 kHz pip	-1.7554	4.9779	-0.36881	0.929	0.739
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 18 kHz pip	1.2510	3.6416	0.12173	0.910	0.745
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 24 kHz pip	-4.7444	6.0064	-0.85818	0.773	0.465
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 30 kHz pip	-0.44666	3.7424	-0.095475	0.972	0.910
body composition	body weight (at time of DXA)	-1.8141	0.71561	-1.1182	0.0789	0.0160
body composition	bone area, whole body scan, head excluded	0.25109	0.18612	1.2772	0.451	0.186
body composition	bone mineral content of whole body scan, head excluded	0.0049867	0.014863	0.43073	0.885	0.739
body composition	bone mineral content to body weight ratio	0.00025671	0.00060188	0.50383	0.835	0.673
body composition	bone mineral density of whole body scan, head excluded	-0.00083642	0.00076088	-0.87920	0.579	0.280
body composition	fat tissue mass of whole body scan, head excluded	-0.43249	0.35913	-0.79806	0.479	0.237
body composition	fat tissue mass to body weight ratio	-0.015244	0.012252	-0.66254	0.451	0.222
body composition	lean tissue mass of whole body scan, head excluded	0.091077	0.33610	0.035504	0.918	0.788
body composition	lean tissue mass to body weight ratio	0.019804	0.010879	0.98244	0.266	0.0775
body composition	percent fat, whole body scan, head excluded	-1.5828	1.1920	-0.74474	0.424	0.193
body composition	ratio of soft-tissue attenuation coefficients	0.0017579	0.0013252	0.74490	0.426	0.194
body composition	tissue area	0.056895	0.17626	0.38812	0.911	0.749
body composition	total tissue mass, whole body scan, head excluded	-0.13373	0.20224	-0.54614	0.727	0.513
clinical blood chemistry	alanine transaminase (plasma ALT)	5.3605	2.3675	0.41781	0.324	0.0378
clinical blood chemistry	albumin (plasma Alb)	1.0576	0.52842	1.5523	0.318	0.0638
clinical blood chemistry	alkaline phosphatase (plasma ALP)	2.3799	4.4193	-0.12145	0.790	0.598
clinical blood chemistry	aspartate transaminase (plasma AST)	1.7328	15.790	0.093710	0.980	0.914
clinical blood chemistry	aspartate transaminase to alanine transaminase ratio (plasma AST:ALT)	-0.21996	0.43969	-0.70601	0.875	0.624
clinical blood chemistry	blood urea nitrogen (BUN)	3.6617	1.2548	1.4009	0.0861	0.0101
clinical blood chemistry	calcium (plasma Ca)	0.061129	0.071929	0.77384	0.642	0.408
clinical blood chemistry	creatinine (plasma)	0.035520	0.015004	0.97233	0.157	0.0318
clinical blood chemistry	glucose (plasma GLU, no fast)	-22.500	13.770	-0.55330	0.296	0.123
clinical blood chemistry	HDL cholesterol (plasma HDL)	0.90690	3.4537	-0.10719	0.926	0.796
clinical blood chemistry	HDL cholesterol to total cholesterol ratio	0.012511	0.010980	0.52816	0.610	0.271
clinical blood chemistry	phosphorus (plasma phosphate)	0.31052	0.38399	0.42188	0.702	0.431
clinical blood chemistry	total bilirubin (plasma TBIL)	0.017961	0.010841	1.1041	0.406	0.117
clinical blood chemistry	total cholesterol (plasma CHOL, no fast)	0.29154	4.5086	-0.18518	0.981	0.949
clinical blood chemistry	total protein (plasma TP)	2.0338	0.75811	1.3955	0.137	0.0163
clinical blood chemistry	triglyceride (plasma TG, no fast)	-51.089	11.148	-1.8217	0.0211	0.000306
glucose tolerance test	amount glucose injected	0.91807	2.1739	0.63656	0.892	0.676
glucose tolerance test	plasma glucose, 0min	-1.3675	5.9358	-0.37514	0.913	0.819
glucose tolerance test	plasma glucose, 15min	3.3259	20.627	0.20178	0.954	0.873
glucose tolerance test	plasma glucose, 30min	25.723	21.572	0.87778	0.577	0.242
glucose tolerance test	plasma glucose, 60min	1.8866	13.540	0.20599	0.951	0.890
glucose tolerance test	plasma glucose, 120min	-1.4710	7.5199	-0.22847	0.940	0.846
grip strength	body weight (at time of grip strength test)	-0.88559	0.58748	-0.58601	0.309	0.145
grip strength	forelimb and hindlimb grip strength (mean of trials), average	11.270	7.1114	1.0820	0.296	0.126
grip strength	forelimb and hindlimb grip strength (mean of trials), average normalized to bw	0.55892	0.32915	1.0189	0.265	0.103
grip strength	forelimb and hindlimb grip strength by trial, trial1	-2.5994	10.885	0.037768	0.931	0.813
grip strength	forelimb and hindlimb grip strength by trial, trial2	20.323	11.909	1.4881	0.300	0.101
grip strength	forelimb and hindlimb grip strength by trial, trial3	12.325	10.944	1.0263	0.539	0.271
grip strength	forelimb grip strength (mean of trials), average	4.3871	6.7873	0.85035	0.756	0.524
grip strength	forelimb grip strength (mean of trials), average normalized to bw	0.23667	0.31531	0.85243	0.722	0.461
grip strength	forelimb grip strength by trial, trial1	19.463	7.7947	2.1684	0.181	0.0198
grip strength	forelimb grip strength by trial, trial2	-0.82581	8.7809	0.13401	0.973	0.926
grip strength	forelimb grip strength by trial, trial3	-4.8428	6.9509	-0.29315	0.764	0.493
heart weight	heart weight, normalized to body weight	-0.24653	0.17371	-1.3850	0.377	0.173
heart weight	heart weight, weight	-5.8127	4.9220	-1.1712	0.464	0.254
hematology	basophil differential (percent of total WBC)	-0.025883	0.046126	-0.37367	0.855	0.580
hematology	calculated hemoglobin (cHGB)	-0.012614	0.25195	-0.31818	0.984	0.960
hematology	eosinophil differential (percent of total WBC)	-0.31352	0.20285	-0.76532	0.526	0.135
hematology	hematocrit (HCT)	0.59506	0.81483	0.28823	0.712	0.472
hematology	hemoglobin concentration distribution width (HDW)	-0.00099918	0.030879	-0.013907	0.984	0.974
hematology	large unstained cells (percent of total WBC)	-0.0082244	0.092213	-0.013029	0.964	0.930
hematology	lymphocyte differential (percent of total WBC)	3.7954	2.1590	1.2258	0.307	0.0915
hematology	mean corpuscular hemoglobin (CHr)	-0.038622	0.095837	-0.31264	0.847	0.691
hematology	mean platelet volume (MPV)	0.093005	0.061803	0.44432	0.335	0.146
hematology	mean RBC corpuscular hemoglobin (MCH)	-0.13940	0.13293	-0.53382	0.658	0.305
hematology	mean RBC corpuscular hemoglobin concentration (MCHC)	-0.79872	0.21852	-1.1444	0.0491	0.00132
hematology	mean RBC corpuscular volume (MCV)	0.36157	0.34334	0.64813	0.535	0.303
hematology	measured hemoglobin (mHGB)	-0.088947	0.30311	-0.46703	0.895	0.772
hematology	monocyte differential (percent of total WBC)	-0.0086209	0.14330	0.18279	0.983	0.953
hematology	neutrophil differential (percent of total WBC)	-2.8489	2.1650	-1.1121	0.451	0.201
hematology	platelet count (PLT; units per volume x 10³)	91.344	68.624	1.2143	0.566	0.196
hematology	RBC corpuscular distribution width (RDW)	0.16312	0.47114	0.54607	0.864	0.732
hematology	RBC corpuscular hemoglobin concentration mean (CHCM)	-0.47462	0.13445	-1.2582	0.0228	0.00179
hematology	red blood cell count (RBC; per volume x 10⁶)	0.047061	0.17044	-0.13449	0.898	0.785
hematology	reticulocyte count (Retic; units per volume x 10⁹)	4.6083	26.949	0.30332	0.961	0.866
hematology	reticulocyte differential (percent of total RBC)	0.032472	0.34379	0.35368	0.976	0.926
hematology	white blood cell count (WBC; units per volume x 10³)	0.78229	0.66920	0.70658	0.460	0.254
holeboard	number of hole pokes by individual hole number, 20 min test, 1	0.051202	0.74190	0.097211	0.980	0.945
holeboard	number of hole pokes by individual hole number, 20 min test, 2	0.18309	0.55817	0.43073	0.948	0.745
holeboard	number of hole pokes by individual hole number, 20 min test, 3	0.14740	0.39159	0.33801	0.937	0.709
holeboard	number of hole pokes by individual hole number, 20 min test, 4	-0.46470	0.49166	-0.39215	0.774	0.350
holeboard	number of hole pokes by individual hole number, 20 min test, 5	-0.15855	0.35326	-0.15849	0.934	0.656
holeboard	number of hole pokes by individual hole number, 20 min test, 6	-0.23717	0.25522	-0.65451	0.870	0.358
holeboard	number of hole pokes by individual hole number, 20 min test, 7	0.87044	0.30687	1.8660	0.503	0.00712
holeboard	number of hole pokes by individual hole number, 20 min test, 8	-0.22120	0.36231	-0.25858	0.892	0.545
holeboard	number of hole pokes by individual hole number, 20 min test, 9	0.56628	0.35640	1.0498	0.573	0.120
holeboard	number of hole pokes by individual hole number, 20 min test, 10	0.031630	0.33869	0.15795	0.983	0.926
holeboard	number of hole pokes by individual hole number, 20 min test, 11	-0.38324	0.25324	-1.0181	0.708	0.138
holeboard	number of hole pokes by individual hole number, 20 min test, 12	-0.12487	0.44588	-0.10477	0.952	0.781
holeboard	number of hole pokes by individual hole number, 20 min test, 13	-0.86717	0.62635	-0.76974	0.587	0.174
holeboard	number of hole pokes by individual hole number, 20 min test, 14	0.21429	0.41716	0.43876	0.872	0.610
holeboard	number of hole pokes by individual hole number, 20 min test, 15	-0.56478	0.40457	-0.81359	0.643	0.170
holeboard	number of hole pokes by individual hole number, 20 min test, 16	0.14478	0.81236	0.15752	0.959	0.859
holeboard	total number of hole pokes, 20 min test	-0.85033	3.3066	-0.026993	0.907	0.798
light / dark	fecal boli count, 20 min test	0.75080	0.53094	0.85675	0.575	0.165
light / dark	latency to enter dark zone, 20 min test	-40.578	36.452	-0.86851	0.684	0.272
light / dark	number of transitions between light and dark zones, 20 min test	-12.165	7.4102	-1.1239	0.400	0.108
light / dark	percentage of total time in dark zone, 20 min test	3.7697	3.7806	0.78663	0.673	0.324
light / dark	percentage of total time in light zone, 20 min test	-3.7697	3.7806	-0.79217	0.672	0.324
light / dark	time mobile in dark zone, 20 min test	20.343	11.136	0.97609	0.299	0.0747
light / dark	time mobile in light zone, 20 min test	-4.3419	11.500	-0.56867	0.859	0.708
light / dark	time spent in dark zone, 20 min test	48.818	50.688	0.95242	0.722	0.341
light / dark	time spent in light zone, 20 min test	-48.818	50.688	-0.95242	0.722	0.341
open field	average speed in center of arena, 20 min test	-0.52209	0.40387	-1.0812	0.541	0.203
open field	average speed in periphery of arena, 20 min test	-0.12382	0.12048	-0.99825	0.537	0.310
open field	distance traveled habituation ratio, 20 min test	22.652	7.7773	1.7012	0.0802	0.00572
open field	distance traveled in center of arena, 20 min test	-115.04	89.848	-1.1081	0.459	0.207
open field	distance traveled in periphery of arena, 20 min test	-93.953	113.43	-0.80284	0.655	0.412
open field	distance traveled slope, 20 min test	21.612	7.2347	1.7425	0.0741	0.00468
open field	distance traveled, 20 min test, 1st 5min	-189.85	68.045	-1.7244	0.0556	0.00789
open field	distance traveled, 20 min test, 2nd 5min	-33.789	46.284	-0.89126	0.695	0.469
open field	distance traveled, 20 min test, 3rd 5min	10.108	47.264	-0.30894	0.928	0.832
open field	distance traveled, 20 min test, 4th 5min	21.979	43.329	-0.21169	0.798	0.615
open field	number of clockwise revolution episodes, 20 min test	-2.1215	1.2356	-1.6785	0.398	0.0933
open field	number of counter-clockwise revolution episodes, 20 min test	0.36103	0.89452	-0.24476	0.849	0.689
open field	number of fecal boli, 20 min test	1.5020	0.85807	1.3425	0.347	0.0873
open field	number of rears in 5 min bins, 20 min test, 1st 5min	-1.8736	1.8269	-0.70087	0.574	0.311
open field	number of rears in 5 min bins, 20 min test, 2nd 5min	-0.82265	2.7926	-0.55562	0.896	0.770
open field	number of rears in 5 min bins, 20 min test, 3rd 5min	-4.2406	2.8924	-1.2685	0.408	0.150
open field	number of rears in 5 min bins, 20 min test, 4th 5min	-4.3243	2.5994	-1.2685	0.340	0.104
open field	percentage of total time in center of arena, 20 min test	-2.9687	3.1743	-0.91753	0.669	0.355
open field	percentage of total time in center of arena, slope, 20 min test	-4.5791	1.9510	-2.1562	0.367	0.0237
open field	percentage of total time in center, habituation ratio, 20 min test	-5.2043	2.0137	-2.2306	0.303	0.0133
open field	percentage of total time in corners of arena, 20 min test	6.5997	4.0733	1.4706	0.412	0.113
open field	percentage of total time in corners, habituation ratio, 20 min test	3.3947	1.9601	1.1805	0.548	0.0908
open field	percentage of total time in corners, slope, 20 min test	3.3699	1.9439	1.2304	0.545	0.0905
open field	permanence time in center of arena, 20 min test	-35.617	38.092	-0.91753	0.670	0.355
open field	permanence time in corners of arena, 20 min test	79.212	48.875	1.4706	0.412	0.113
open field	permanence time in periphery of arena, 20 min test	35.637	38.100	0.91753	0.670	0.355
open field	total distance traveled, 20 min test	-204.01	155.12	-1.0836	0.398	0.196
open field	total number of rears, 20 min test	-11.207	8.6963	-1.1358	0.444	0.205
open field	whole arena average speed, 20 min test	-0.17102	0.12944	-1.0885	0.395	0.194
open field	whole arena resting time, 20 min test	22.612	14.535	1.1832	0.293	0.127
open field	whole arena time spent mobile, 20 min test	-22.577	14.543	-1.3992	0.300	0.128
open field	whole arena time spent vertical, 20 min test	-8.9079	7.7499	-0.81588	0.559	0.257
SHIRPA	locomotor activity (number of squares in the arena the mouse moves into with all four paws in first 30 s of test)	-0.031447	2.1895	0.17402	0.997	0.989
startle / PPI	average baseline movement during background noise	-0.046648	1.0486	0.045553	0.997	0.965
startle / PPI	average of each corrected maximum percent pre-pulse inhibition value	0.14631	0.063920	1.1713	0.242	0.0284
startle / PPI	average of each corrected percent pre-pulse inhibition value	0.11088	0.062617	0.97604	0.376	0.0856
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	0.51492	6.7220	0.12008	0.995	0.939
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	14.139	6.6849	1.4055	0.317	0.0418
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	6.5302	15.821	0.58603	0.881	0.682
startle / PPI	average startle response to full pulse (120 dB)	-97.661	41.808	-1.3943	0.122	0.0255
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-88.745	42.986	-1.2562	0.168	0.0467
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-126.47	40.170	-1.9118	0.0289	0.00341
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-76.296	65.093	-1.3833	0.468	0.250
startle / PPI	average startle response to pre-pulse, 74dB sound pressure level	0.57055	1.2490	0.45909	0.933	0.651
startle / PPI	average startle response to pre-pulse, 78dB sound pressure level	-1.1220	1.9788	-0.78087	0.913	0.574
startle / PPI	average startle response to pre-pulse, 82dB sound pressure level	2.4150	3.2877	0.85932	0.807	0.468
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	0.012329	0.073701	0.15545	0.976	0.868
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	0.14262	0.075375	1.0883	0.352	0.0670
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	0.13096	0.066816	0.81515	0.221	0.0585
startle / PPI	corrected average startle response to full pulse (120 dB) minus average baseline movement during background noise	-97.364	41.616	-1.3906	0.120	0.0253
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 74dB sound pressure level	-89.316	43.396	-1.2470	0.168	0.0473
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 78dB sound pressure level	-125.35	40.837	-1.8620	0.0332	0.00419
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 82dB sound pressure level	-89.334	31.938	-1.5952	0.0570	0.00843
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	0.016622	0.076008	0.18958	0.974	0.828
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	0.20828	0.078299	1.5608	0.180	0.0118
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	0.16911	0.066733	1.0062	0.113	0.0162
startle / PPI	corrected maximum startle response to full pulse (120 dB) minus maximum baseline movement during background noise	-314.09	155.67	-1.2844	0.184	0.0516
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 74dB sound pressure level	-291.71	154.83	-1.1439	0.218	0.0681
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 78dB sound pressure level	-490.97	152.11	-2.0288	0.0240	0.00276
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 82dB sound pressure level	-354.63	125.41	-1.7351	0.0536	0.00791
startle / PPI	maximum baseline movement during background noise	-1.4151	2.8431	-0.37500	0.906	0.622
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	1.2600	7.1741	0.17961	0.988	0.862
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	20.252	7.3697	1.8620	0.175	0.00952
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	14.753	6.1075	1.1996	0.154	0.0214
startle / PPI	maximum startle response to full pulse (120 dB)	-315.50	156.26	-1.2749	0.185	0.0514
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-290.76	154.09	-1.1439	0.219	0.0677
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-492.93	151.26	-2.0179	0.0224	0.00254
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-343.79	125.32	-1.7043	0.0610	0.00975
startle / PPI	maximum startle response to pre-pulse, 74dB sound pressure level	0.94616	3.0584	0.43586	0.951	0.759
startle / PPI	maximum startle response to pre-pulse, 78dB sound pressure level	-1.9568	4.8273	-0.53036	0.939	0.688
startle / PPI	maximum startle response to pre-pulse, 82dB sound pressure level	8.5519	4.8271	1.1253	0.452	0.0854

MULTIPLE (CATEGORICAL) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

Procedure	JaxKOMP-EAP Trait	Sex	Trait Effect	P-value
eye morphology	anterior chamber depth	females	1.0 %	1.0
eye morphology	anterior chamber depth	males	0.0 %	1.0
eye morphology	anterior chamber depth	both	1.0 %	1.0
eye morphology	bulging eye	females	1.0 %	1.0
eye morphology	bulging eye	males	0.0 %	1.0
eye morphology	bulging eye	both	1.0 %	1.00
eye morphology	cornea	females	4.0 %	1.0
eye morphology	cornea	males	2.0 %	1.0
eye morphology	cornea	both	3.0 %	1.00
eye morphology	cornea opacity	females	12.0 %	0.195
eye morphology	cornea opacity	males	1.0 %	1.0
eye morphology	cornea opacity	both	6.0 %	0.234
eye morphology	cornea vascularization	females	3.0 %	1.0
eye morphology	cornea vascularization	males	1.0 %	1.0
eye morphology	cornea vascularization	both	2.0 %	1.0
eye morphology	corneal deposits	females	2.0 %	1.0
eye morphology	corneal deposits	males	1.0 %	1.0
eye morphology	corneal deposits	both	1.0 %	1.00
eye morphology	corneal mineralization	females	2.0 %	1.0
eye morphology	corneal mineralization	males	1.0 %	1.0
eye morphology	corneal mineralization	both	1.0 %	1.0
eye morphology	corneal scleralization	females	3.0 %	1.00
eye morphology	corneal scleralization	males	1.0 %	1.0
eye morphology	corneal scleralization	both	2.0 %	1.0
eye morphology	corneal ulcer	females	1.0 %	1.0
eye morphology	corneal ulcer	males	1.0 %	1.0
eye morphology	corneal ulcer	both	1.0 %	1.0
eye morphology	eye closure	females	1.0 %	1.00
eye morphology	eye closure	males	0.0 %	1.0
eye morphology	eye closure	both	1.0 %	1.0
eye morphology	eye hemorrhage or blood presence	females	2.0 %	1.00
eye morphology	eye hemorrhage or blood presence	males	1.0 %	1.0
eye morphology	eye hemorrhage or blood presence	both	1.0 %	1.0
eye morphology	eyelid morphology	females	1.0 %	1.0
eye morphology	eyelid morphology	males	0.0 %	1.0
eye morphology	eyelid morphology	both	1.0 %	1.0
eye morphology	eyes (present, absent)	females	1.0 %	1.0
eye morphology	eyes (present, absent)	males	0.0 %	1.0
eye morphology	eyes (present, absent)	both	0.0 %	1.0
eye morphology	fusion between cornea and lens	females	4.0 %	1.00
eye morphology	fusion between cornea and lens	males	2.0 %	1.0
eye morphology	fusion between cornea and lens	both	3.0 %	1.0
eye morphology	iris pigmentation	females	2.0 %	1.0
eye morphology	iris pigmentation	males	1.0 %	1.0
eye morphology	iris pigmentation	both	2.0 %	1.0
eye morphology	iris transillumination	females	2.0 %	1.00
eye morphology	iris transillumination	males	1.0 %	1.00
eye morphology	iris transillumination	both	1.0 %	1.00
eye morphology	irispupil	females	12.0 %	0.0969
eye morphology	irispupil	males	3.0 %	1.0
eye morphology	irispupil	both	6.0 %	0.285
eye morphology	lacrimation	females	3.0 %	1.0
eye morphology	lacrimation	males	2.0 %	1.0
eye morphology	lacrimation	both	3.0 %	1.0
eye morphology	lens	females	10.0 %	1.00
eye morphology	lens	males	8.0 %	1.00
eye morphology	lens	both	9.0 %	1.0
eye morphology	lens opacity	females	11.0 %	0.316
eye morphology	lens opacity	males	12.0 %	0.331
eye morphology	lens opacity	both	6.0 %	0.264
eye morphology	narrow eye opening	females	2.0 %	1.0
eye morphology	narrow eye opening	males	1.0 %	1.0
eye morphology	narrow eye opening	both	1.0 %	1.00
eye morphology	optic disc	females	4.0 %	1.00
eye morphology	optic disc	males	41.0 %	0.0000170
eye morphology	optic disc	both	17.0 %	0.000178
eye morphology	persistence of hyaloid vascular system	females	24.0 %	0.0719
eye morphology	persistence of hyaloid vascular system	males	5.0 %	1.0
eye morphology	persistence of hyaloid vascular system	both	12.0 %	0.129
eye morphology	pupil dilation	females	2.0 %	1.0
eye morphology	pupil dilation	males	1.0 %	1.00
eye morphology	pupil dilation	both	2.0 %	1.0
eye morphology	pupil light response	females	2.0 %	1.00
eye morphology	pupil light response	males	1.0 %	1.0
eye morphology	pupil light response	both	2.0 %	1.0
eye morphology	pupil position	females	4.0 %	1.00
eye morphology	pupil position	males	3.0 %	1.0
eye morphology	pupil position	both	4.0 %	1.0
eye morphology	pupil shape	females	3.0 %	1.00
eye morphology	pupil shape	males	2.0 %	1.0
eye morphology	pupil shape	both	3.0 %	1.0
eye morphology	retina	females	15.0 %	0.202
eye morphology	retina	males	27.0 %	0.107
eye morphology	retina	both	21.0 %	0.0768
eye morphology	retinal blood vessels	females	4.0 %	1.0
eye morphology	retinal blood vessels	males	2.0 %	1.0
eye morphology	retinal blood vessels	both	3.0 %	1.0
eye morphology	retinal blood vessels pattern	females	5.0 %	1.0
eye morphology	retinal blood vessels pattern	males	2.0 %	1.00
eye morphology	retinal blood vessels pattern	both	4.0 %	1.00
eye morphology	retinal blood vessels structure	females	4.0 %	1.00
eye morphology	retinal blood vessels structure	males	2.0 %	1.0
eye morphology	retinal blood vessels structure	both	3.0 %	1.0
eye morphology	retinal pigmentation	females	23.0 %	0.103
eye morphology	retinal pigmentation	males	44.0 %	0.00653
eye morphology	retinal pigmentation	both	27.0 %	0.0180
eye morphology	retinal structure	females	4.0 %	1.00
eye morphology	retinal structure	males	2.0 %	1.00
eye morphology	retinal structure	both	3.0 %	1.00
eye morphology	synechia	females	4.0 %	1.0
eye morphology	synechia	males	2.0 %	1.00
eye morphology	synechia	both	3.0 %	1.00
eye morphology	vitreous	females	4.0 %	1.00
eye morphology	vitreous	males	2.0 %	1.0
eye morphology	vitreous	both	3.0 %	1.0
SHIRPA	activity body position	females	1.0 %	1.0
SHIRPA	activity body position	males	2.0 %	1.0
SHIRPA	activity body position	both	1.0 %	1.00
SHIRPA	aggression	females	0.0 %	1.00
SHIRPA	aggression	males	1.0 %	1.0
SHIRPA	aggression	both	1.0 %	1.00
SHIRPA	body length	females	0.0 %	1.0
SHIRPA	body length	males	0.0 %	1.0
SHIRPA	body length	both	0.0 %	1.0
SHIRPA	body position	females	0.0 %	1.0
SHIRPA	body position	males	1.0 %	1.0
SHIRPA	body position	both	0.0 %	1.00
SHIRPA	body thickness	females	1.0 %	1.0
SHIRPA	body thickness	males	0.0 %	1.0
SHIRPA	body thickness	both	0.0 %	1.00
SHIRPA	coat color abdomen	females	3.0 %	1.00
SHIRPA	coat color abdomen	males	4.0 %	1.00
SHIRPA	coat color abdomen	both	4.0 %	1.00
SHIRPA	coat color back	females	0.0 %	1.0
SHIRPA	coat color back	males	0.0 %	1.0
SHIRPA	coat color back	both	0.0 %	1.00
SHIRPA	coat color head	females	0.0 %	1.0
SHIRPA	coat color head	males	0.0 %	1.0
SHIRPA	coat color head	both	0.0 %	1.0
SHIRPA	coat color pattern abdomen	females	1.0 %	1.0
SHIRPA	coat color pattern abdomen	males	1.0 %	1.0
SHIRPA	coat color pattern abdomen	both	1.0 %	1.00
SHIRPA	coat color pattern back	females	0.0 %	1.0
SHIRPA	coat color pattern back	males	0.0 %	1.0
SHIRPA	coat color pattern back	both	0.0 %	1.00
SHIRPA	coat color pattern head	females	0.0 %	1.0
SHIRPA	coat color pattern head	males	0.0 %	1.00
SHIRPA	coat color pattern head	both	0.0 %	1.0
SHIRPA	coat hair abdomen texture appearance	females	2.0 %	1.0
SHIRPA	coat hair abdomen texture appearance	males	2.0 %	1.0
SHIRPA	coat hair abdomen texture appearance	both	2.0 %	1.0
SHIRPA	coat hair back texture appearance	females	0.0 %	1.0
SHIRPA	coat hair back texture appearance	males	0.0 %	1.0
SHIRPA	coat hair back texture appearance	both	0.0 %	1.0
SHIRPA	coat hair distribution abdomen	females	0.0 %	1.0
SHIRPA	coat hair distribution abdomen	males	1.0 %	1.0
SHIRPA	coat hair distribution abdomen	both	1.0 %	1.0
SHIRPA	coat hair distribution back	females	0.0 %	1.0
SHIRPA	coat hair distribution back	males	0.0 %	1.0
SHIRPA	coat hair distribution back	both	0.0 %	1.00
SHIRPA	coat hair distribution head	females	1.0 %	1.00
SHIRPA	coat hair distribution head	males	1.0 %	1.0
SHIRPA	coat hair distribution head	both	1.0 %	1.0
SHIRPA	coat hair head texture appearance	females	0.0 %	1.00
SHIRPA	coat hair head texture appearance	males	0.0 %	1.0
SHIRPA	coat hair head texture appearance	both	0.0 %	1.0
SHIRPA	contact righting	females	5.0 %	1.0
SHIRPA	contact righting	males	5.0 %	1.00
SHIRPA	contact righting	both	5.0 %	1.00
SHIRPA	ear morphology	females	0.0 %	1.0
SHIRPA	ear morphology	males	0.0 %	1.0
SHIRPA	ear morphology	both	0.0 %	1.0
SHIRPA	fat distribution	females	0.0 %	1.0
SHIRPA	fat distribution	males	0.0 %	1.0
SHIRPA	fat distribution	both	0.0 %	1.0
SHIRPA	forelimb digit number	females	0.0 %	1.00
SHIRPA	forelimb digit number	males	0.0 %	1.0
SHIRPA	forelimb digit number	both	0.0 %	1.0
SHIRPA	forelimb digit position	females	0.0 %	1.0
SHIRPA	forelimb digit position	males	0.0 %	1.0
SHIRPA	forelimb digit position	both	0.0 %	1.0
SHIRPA	forelimb digit shape	females	0.0 %	1.0
SHIRPA	forelimb digit shape	males	0.0 %	1.0
SHIRPA	forelimb digit shape	both	0.0 %	1.0
SHIRPA	forelimb digit size	females	0.0 %	1.0
SHIRPA	forelimb digit size	males	0.0 %	1.0
SHIRPA	forelimb digit size	both	0.0 %	1.0
SHIRPA	forelimb footpads	females	0.0 %	1.0
SHIRPA	forelimb footpads	males	0.0 %	1.0
SHIRPA	forelimb footpads	both	0.0 %	1.0
SHIRPA	forelimb nail length	females	0.0 %	1.0
SHIRPA	forelimb nail length	males	0.0 %	1.0
SHIRPA	forelimb nail length	both	0.0 %	1.0
SHIRPA	forelimb nail number	females	0.0 %	1.0
SHIRPA	forelimb nail number	males	0.0 %	1.0
SHIRPA	forelimb nail number	both	0.0 %	1.0
SHIRPA	forelimb nail position	females	0.0 %	1.0
SHIRPA	forelimb nail position	males	0.0 %	1.0
SHIRPA	forelimb nail position	both	0.0 %	1.0
SHIRPA	forelimb nail shape	females	0.0 %	1.0
SHIRPA	forelimb nail shape	males	0.0 %	1.0
SHIRPA	forelimb nail shape	both	0.0 %	1.0
SHIRPA	forelimbs position	females	0.0 %	1.0
SHIRPA	forelimbs position	males	0.0 %	1.0
SHIRPA	forelimbs position	both	0.0 %	1.0
SHIRPA	forelimbs shape	females	0.0 %	1.0
SHIRPA	forelimbs shape	males	0.0 %	1.0
SHIRPA	forelimbs shape	both	0.0 %	1.0
SHIRPA	forelimbs size	females	0.0 %	1.0
SHIRPA	forelimbs size	males	0.0 %	1.00
SHIRPA	forelimbs size	both	0.0 %	1.0
SHIRPA	forepaw position	females	0.0 %	1.0
SHIRPA	forepaw position	males	0.0 %	1.0
SHIRPA	forepaw position	both	0.0 %	1.0
SHIRPA	forepaw shape	females	0.0 %	1.0
SHIRPA	forepaw shape	males	0.0 %	1.0
SHIRPA	forepaw shape	both	0.0 %	1.0
SHIRPA	forepaw size	females	0.0 %	1.0
SHIRPA	forepaw size	males	0.0 %	1.0
SHIRPA	forepaw size	both	0.0 %	1.0
SHIRPA	gait (fluidity)	females	0.0 %	1.0
SHIRPA	gait (fluidity)	males	0.0 %	1.0
SHIRPA	gait (fluidity)	both	0.0 %	1.0
SHIRPA	genitalia morphology	females	0.0 %	1.00
SHIRPA	genitalia morphology	males	0.0 %	1.0
SHIRPA	genitalia morphology	both	0.0 %	1.00
SHIRPA	genitalia presence	females	0.0 %	1.0
SHIRPA	genitalia presence	males	0.0 %	1.0
SHIRPA	genitalia presence	both	0.0 %	1.0
SHIRPA	genitalia size	females	0.0 %	1.0
SHIRPA	genitalia size	males	0.0 %	1.00
SHIRPA	genitalia size	both	0.0 %	1.00
SHIRPA	head bobbing	females	0.0 %	1.0
SHIRPA	head bobbing	males	0.0 %	1.0
SHIRPA	head bobbing	both	0.0 %	1.0
SHIRPA	head morphology	females	0.0 %	1.0
SHIRPA	head morphology	males	0.0 %	1.0
SHIRPA	head morphology	both	0.0 %	1.0
SHIRPA	head size	females	0.0 %	1.0
SHIRPA	head size	males	0.0 %	1.00
SHIRPA	head size	both	0.0 %	1.0
SHIRPA	hindlimb digit number	females	1.0 %	1.00
SHIRPA	hindlimb digit number	males	0.0 %	1.0
SHIRPA	hindlimb digit number	both	0.0 %	1.0
SHIRPA	hindlimb digit position	females	0.0 %	1.0
SHIRPA	hindlimb digit position	males	0.0 %	1.0
SHIRPA	hindlimb digit position	both	0.0 %	1.0
SHIRPA	hindlimb digit shape	females	0.0 %	1.0
SHIRPA	hindlimb digit shape	males	0.0 %	1.0
SHIRPA	hindlimb digit shape	both	0.0 %	1.00
SHIRPA	hindlimb digit size	females	0.0 %	1.00
SHIRPA	hindlimb digit size	males	0.0 %	1.00
SHIRPA	hindlimb digit size	both	0.0 %	1.00
SHIRPA	hindlimb nail length	females	0.0 %	1.0
SHIRPA	hindlimb nail length	males	0.0 %	1.00
SHIRPA	hindlimb nail length	both	0.0 %	1.0
SHIRPA	hindlimb nail number	females	0.0 %	1.0
SHIRPA	hindlimb nail number	males	1.0 %	1.00
SHIRPA	hindlimb nail number	both	0.0 %	1.0
SHIRPA	hindlimb nail position	females	0.0 %	1.0
SHIRPA	hindlimb nail position	males	0.0 %	1.0
SHIRPA	hindlimb nail position	both	0.0 %	1.0
SHIRPA	hindlimb nail shape	females	0.0 %	1.0
SHIRPA	hindlimb nail shape	males	0.0 %	1.0
SHIRPA	hindlimb nail shape	both	0.0 %	1.0
SHIRPA	hindlimbs footpads	females	0.0 %	1.0
SHIRPA	hindlimbs footpads	males	0.0 %	1.0
SHIRPA	hindlimbs footpads	both	0.0 %	1.0
SHIRPA	hindlimbs position	females	0.0 %	1.0
SHIRPA	hindlimbs position	males	0.0 %	1.0
SHIRPA	hindlimbs position	both	0.0 %	1.0
SHIRPA	hindlimbs shape	females	0.0 %	1.0
SHIRPA	hindlimbs shape	males	0.0 %	1.0
SHIRPA	hindlimbs shape	both	0.0 %	1.0
SHIRPA	hindlimbs size	females	0.0 %	1.0
SHIRPA	hindlimbs size	males	0.0 %	1.0
SHIRPA	hindlimbs size	both	0.0 %	1.0
SHIRPA	hindpaw position	females	0.0 %	1.0
SHIRPA	hindpaw position	males	0.0 %	1.0
SHIRPA	hindpaw position	both	0.0 %	1.0
SHIRPA	hindpaw shape	females	0.0 %	1.0
SHIRPA	hindpaw shape	males	0.0 %	1.0
SHIRPA	hindpaw shape	both	0.0 %	1.0
SHIRPA	hindpaw size	females	0.0 %	1.0
SHIRPA	hindpaw size	males	0.0 %	1.0
SHIRPA	hindpaw size	both	0.0 %	1.0
SHIRPA	limb grasp	females	16.0 %	0.154
SHIRPA	limb grasp	males	9.0 %	0.337
SHIRPA	limb grasp	both	13.0 %	0.0913
SHIRPA	lower lip morphology	females	0.0 %	1.0
SHIRPA	lower lip morphology	males	0.0 %	1.0
SHIRPA	lower lip morphology	both	0.0 %	1.0
SHIRPA	lower teeth appearance	females	0.0 %	1.0
SHIRPA	lower teeth appearance	males	0.0 %	1.0
SHIRPA	lower teeth appearance	both	0.0 %	1.0
SHIRPA	mouth morphology	females	0.0 %	1.0
SHIRPA	mouth morphology	males	0.0 %	1.0
SHIRPA	mouth morphology	both	0.0 %	1.0
SHIRPA	salivation	females	0.0 %	1.0
SHIRPA	salivation	males	0.0 %	1.0
SHIRPA	salivation	both	0.0 %	1.0
SHIRPA	skin color back paws	females	0.0 %	1.0
SHIRPA	skin color back paws	males	0.0 %	1.0
SHIRPA	skin color back paws	both	0.0 %	1.0
SHIRPA	skin color ear	females	0.0 %	1.0
SHIRPA	skin color ear	males	0.0 %	1.0
SHIRPA	skin color ear	both	0.0 %	1.0
SHIRPA	skin color front paws	females	0.0 %	1.0
SHIRPA	skin color front paws	males	0.0 %	1.0
SHIRPA	skin color front paws	both	0.0 %	1.0
SHIRPA	skin color snout	females	0.0 %	1.0
SHIRPA	skin color snout	males	0.0 %	1.0
SHIRPA	skin color snout	both	0.0 %	1.0
SHIRPA	skin color tail	females	0.0 %	1.0
SHIRPA	skin color tail	males	0.0 %	1.0
SHIRPA	skin color tail	both	0.0 %	1.0
SHIRPA	skin color whole body	females	0.0 %	1.0
SHIRPA	skin color whole body	males	0.0 %	1.0
SHIRPA	skin color whole body	both	0.0 %	1.0
SHIRPA	skin texture back paw	females	0.0 %	1.0
SHIRPA	skin texture back paw	males	0.0 %	1.0
SHIRPA	skin texture back paw	both	0.0 %	1.0
SHIRPA	skin texture ear	females	0.0 %	1.0
SHIRPA	skin texture ear	males	0.0 %	1.0
SHIRPA	skin texture ear	both	0.0 %	1.0
SHIRPA	skin texture front paws	females	0.0 %	1.0
SHIRPA	skin texture front paws	males	0.0 %	1.0
SHIRPA	skin texture front paws	both	0.0 %	1.0
SHIRPA	skin texture snout	females	0.0 %	1.0
SHIRPA	skin texture snout	males	0.0 %	1.0
SHIRPA	skin texture snout	both	0.0 %	1.0
SHIRPA	skin texture tail	females	0.0 %	1.0
SHIRPA	skin texture tail	males	0.0 %	1.0
SHIRPA	skin texture tail	both	0.0 %	1.0
SHIRPA	skin texture whole body	females	0.0 %	1.0
SHIRPA	skin texture whole body	males	0.0 %	1.0
SHIRPA	skin texture whole body	both	0.0 %	1.00
SHIRPA	snout size	females	0.0 %	1.0
SHIRPA	snout size	males	1.0 %	1.0
SHIRPA	snout size	both	0.0 %	1.0
SHIRPA	startle response	females	0.0 %	1.00
SHIRPA	startle response	males	0.0 %	1.00
SHIRPA	startle response	both	0.0 %	1.0
SHIRPA	tail curvature	females	0.0 %	1.00
SHIRPA	tail curvature	males	0.0 %	1.0
SHIRPA	tail curvature	both	0.0 %	1.00
SHIRPA	tail elevation	females	1.0 %	1.00
SHIRPA	tail elevation	males	2.0 %	1.0
SHIRPA	tail elevation	both	1.0 %	1.0
SHIRPA	tail length	females	0.0 %	1.0
SHIRPA	tail length	males	0.0 %	1.00
SHIRPA	tail length	both	0.0 %	1.0
SHIRPA	tail morphology	females	0.0 %	1.00
SHIRPA	tail morphology	males	0.0 %	1.00
SHIRPA	tail morphology	both	0.0 %	1.00
SHIRPA	tail presence	females	0.0 %	1.0
SHIRPA	tail presence	males	0.0 %	1.0
SHIRPA	tail presence	both	0.0 %	1.0
SHIRPA	tail shape	females	0.0 %	1.0
SHIRPA	tail shape	males	0.0 %	1.0
SHIRPA	tail shape	both	0.0 %	1.0
SHIRPA	tail thickness	females	0.0 %	1.0
SHIRPA	tail thickness	males	0.0 %	1.0
SHIRPA	tail thickness	both	0.0 %	1.0
SHIRPA	teeth presence	females	0.0 %	1.0
SHIRPA	teeth presence	males	0.0 %	1.0
SHIRPA	teeth presence	both	0.0 %	1.0
SHIRPA	transfer arousal	females	1.0 %	1.0
SHIRPA	transfer arousal	males	2.0 %	1.0
SHIRPA	transfer arousal	both	1.0 %	1.0
SHIRPA	tremor	females	0.0 %	1.0
SHIRPA	tremor	males	0.0 %	1.0
SHIRPA	tremor	both	0.0 %	1.00
SHIRPA	trunk curl	females	0.0 %	1.00
SHIRPA	trunk curl	males	0.0 %	1.0
SHIRPA	trunk curl	both	0.0 %	1.00
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	females	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	males	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	both	0.0 %	1.0
SHIRPA	upper lip morphology	females	0.0 %	1.0
SHIRPA	upper lip morphology	males	0.0 %	1.0
SHIRPA	upper lip morphology	both	0.0 %	1.0
SHIRPA	upper teeth appearance	females	0.0 %	1.0
SHIRPA	upper teeth appearance	males	0.0 %	1.00
SHIRPA	upper teeth appearance	both	0.0 %	1.0
SHIRPA	vibrissae appearance	females	2.0 %	1.0
SHIRPA	vibrissae appearance	males	1.0 %	1.0
SHIRPA	vibrissae appearance	both	1.0 %	1.0
SHIRPA	vibrissae presence	females	2.0 %	1.00
SHIRPA	vibrissae presence	males	1.0 %	1.0
SHIRPA	vibrissae presence	both	2.0 %	1.0
SHIRPA	vocalization	females	2.0 %	1.00
SHIRPA	vocalization	males	2.0 %	1.0
SHIRPA	vocalization	both	2.0 %	1.0

GENOTYPE CORRELATION PLOT

Correlate Ahsa1^em1(IMPC)J -/- with genotype: