MPD: JaxKOMP-EAP genotype: Nars2<sup>em1(IMPC)J</sup> -/+

JaxKOMP-EAP effect sizes: Nars2^em1(IMPC)J -/+ Gene Nars2

MULTIPLE (NUMERIC) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

Procedure	JaxKOMP-EAP Trait	Trait Effect	Trait Effect SE	Trait Effect RankZ	Adjusted p-value	Unadjusted p-value
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 6 kHz pip	1.0641	1.9391	0.049000	0.876	0.612
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 12 kHz pip	2.4251	2.5098	0.56833	0.806	0.389
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 18 kHz pip	1.7786	2.9806	0.21249	0.847	0.583
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 24 kHz pip	0.061513	6.9977	-0.10363	1.00	0.993
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 30 kHz pip	-3.2775	2.8740	-0.53311	0.678	0.318
body composition	body length	-0.041952	0.035252	-0.28611	0.539	0.240
body composition	body weight (at time of DXA)	0.58997	0.60121	0.57214	0.553	0.331
body composition	bone area, whole body scan, head excluded	-0.40121	0.14259	-1.2619	0.0665	0.00703
body composition	bone mineral content of whole body scan, head excluded	-0.016596	0.0095000	-0.76288	0.295	0.0869
body composition	bone mineral content to body weight ratio	-0.00091089	0.00038814	-0.94798	0.127	0.0230
body composition	bone mineral density of whole body scan, head excluded	0.00041429	0.00047208	0.47870	0.675	0.384
body composition	fat tissue mass of whole body scan, head excluded	0.073735	0.30594	0.11768	0.910	0.811
body composition	fat tissue mass to body weight ratio	0.0020734	0.010756	0.17565	0.932	0.848
body composition	lean tissue mass of whole body scan, head excluded	0.47031	0.29384	0.79994	0.394	0.116
body composition	lean tissue mass to body weight ratio	0.0086896	0.0090037	0.41083	0.597	0.339
body composition	percent fat, whole body scan, head excluded	0.040508	1.0202	0.092972	0.985	0.968
body composition	ratio of soft-tissue attenuation coefficients	-0.000035536	0.0011338	-0.089054	0.995	0.975
body composition	tissue area	-0.25513	0.20915	-0.67879	0.523	0.228
body composition	total tissue mass, whole body scan, head excluded	0.49449	0.22384	0.82079	0.153	0.0319
clinical blood chemistry	alanine transaminase (plasma ALT)	0.91837	3.0993	0.074460	0.928	0.769
clinical blood chemistry	albumin (plasma Alb)	-0.31120	0.40649	-0.39039	0.740	0.451
clinical blood chemistry	alkaline phosphatase (plasma ALP)	-2.2710	4.2972	-0.93366	0.791	0.602
clinical blood chemistry	aspartate transaminase (plasma AST)	13.360	9.3124	0.54797	0.484	0.164
clinical blood chemistry	aspartate transaminase to alanine transaminase ratio (plasma AST:ALT)	0.54116	0.28779	1.4100	0.417	0.0718
clinical blood chemistry	blood urea nitrogen (BUN)	-0.43864	1.1999	-0.20128	0.862	0.718
clinical blood chemistry	calcium (plasma Ca)	0.074879	0.076091	0.85712	0.574	0.335
clinical blood chemistry	creatinine (plasma)	0.044357	0.016825	1.2092	0.0974	0.0145
clinical blood chemistry	glucose (plasma GLU, no fast)	15.687	9.5948	0.89578	0.280	0.115
clinical blood chemistry	HDL cholesterol (plasma HDL)	-1.7520	2.9264	-0.71279	0.799	0.555
clinical blood chemistry	HDL cholesterol to total cholesterol ratio	-0.0088248	0.011613	-0.63437	0.748	0.454
clinical blood chemistry	phosphorus (plasma phosphate)	0.29220	0.27329	0.39401	0.582	0.295
clinical blood chemistry	total bilirubin (plasma TBIL)	0.0019058	0.0069986	0.14959	0.922	0.788
clinical blood chemistry	total cholesterol (plasma CHOL, no fast)	0.078231	4.1857	-0.23314	0.995	0.985
clinical blood chemistry	total protein (plasma TP)	-0.10366	0.67379	-0.14179	0.947	0.879
clinical blood chemistry	triglyceride (plasma TG, no fast)	-10.031	9.1643	-0.34434	0.579	0.285
EKG	duration of PQ interval	-0.84125	0.69075	-0.72861	0.786	0.233
EKG	duration of PR interval	-0.74000	0.86056	-0.64196	0.877	0.397
EKG	duration of QRS interval	0.091250	0.36101	0.11308	0.979	0.802
EKG	duration of QT interval	-0.95824	0.88989	-0.73388	0.766	0.290
EKG	duration of QTC interval, calculated by dividing QT interval by square root of preceding RR interval	-0.72921	1.0210	-0.68719	0.920	0.481
EKG	duration of RR interval	-1.3675	1.0413	-0.44997	0.610	0.199
EKG	duration of ST interval	-1.0738	0.82123	-0.80709	0.708	0.201
EKG	heart rate coefficient of variation (signal intensity)	-0.12087	0.90077	0.0060450	0.982	0.894
EKG	heart rate variability, mean of differences between sequential beats; beats per min	-0.80668	6.4518	0.018136	0.977	0.901
EKG	heart rate, beats per min	11.725	8.9531	0.44701	0.592	0.200
EKG	mean R amplitude, mean amplitude of signal measured from isoelectric line to peak of QRS	-0.13258	0.078359	-1.1597	0.422	0.101
EKG	mean SR amplitude, mean amplitude of signal measured from signal minimum line to peak of QRS	-0.21036	0.10464	-1.2558	0.313	0.0535
EKG	number of signals	2.1000	3.0991	0.38836	0.877	0.503
EKG	proportion of number pairs of successive beat-to-beat intervals that exceed 50 ms	3.3091	3.2580	0.70547	0.839	0.318
EKG	QT dispersion, measured as inter-lead variability of QT intervals	-2.1375	2.5571	-0.61983	0.939	0.410
EKG	QTc dispersion, calculated as rate-corrected QT dispersion	-1.8712	2.8188	-0.49275	0.931	0.512
EKG	root mean square of successive differences of neighboring RR intervals	-0.50350	1.5008	-0.15578	0.947	0.740
glucose tolerance test	amount glucose injected	-3.1164	1.7668	-0.52267	0.406	0.0856
glucose tolerance test	plasma glucose, 0min	-3.1688	4.7066	-0.54786	0.714	0.505
glucose tolerance test	plasma glucose, 15min	-0.44698	18.758	0.093482	0.990	0.981
glucose tolerance test	plasma glucose, 30min	-32.222	15.826	-0.89403	0.262	0.0484
glucose tolerance test	plasma glucose, 60min	-17.342	12.522	-0.61119	0.488	0.174
glucose tolerance test	plasma glucose, 120min	4.2796	6.6058	0.16409	0.771	0.521
grip strength	body weight (at time of grip strength test)	0.073591	0.53767	0.28222	0.946	0.892
grip strength	forelimb and hindlimb grip strength (mean of trials), average	-23.128	6.0216	-1.3492	0.00760	0.000546
grip strength	forelimb and hindlimb grip strength (mean of trials), average normalized to bw	-1.0706	0.29648	-1.3243	0.0130	0.00103
grip strength	forelimb and hindlimb grip strength by trial, trial1	-20.086	7.5878	-1.0794	0.0953	0.0125
grip strength	forelimb and hindlimb grip strength by trial, trial2	-23.047	6.4427	-1.2108	0.0241	0.00113
grip strength	forelimb and hindlimb grip strength by trial, trial3	-25.827	7.4216	-1.3749	0.0256	0.00147
grip strength	forelimb grip strength (mean of trials), average	-8.6651	5.1757	-0.79933	0.318	0.104
grip strength	forelimb grip strength (mean of trials), average normalized to bw	-0.39079	0.27807	-0.75996	0.428	0.170
grip strength	forelimb grip strength by trial, trial1	-7.5771	6.3072	-0.62693	0.598	0.238
grip strength	forelimb grip strength by trial, trial2	-6.3301	6.0669	-0.46175	0.630	0.304
grip strength	forelimb grip strength by trial, trial3	-11.791	6.3231	-0.99722	0.315	0.0711
heart weight	heart weight, normalized to body weight	0.037166	0.12195	-0.30817	0.868	0.763
heart weight	heart weight, weight	2.2582	3.1240	-0.076422	0.676	0.477
hematology	basophil differential (percent of total WBC)	-0.033333	0.038602	-0.49284	0.769	0.396
hematology	calculated hemoglobin (cHGB)	-0.018367	0.18237	-0.34389	0.966	0.921
hematology	eosinophil differential (percent of total WBC)	-0.057123	0.30072	-0.093811	0.952	0.851
hematology	hematocrit (HCT)	0.22755	0.54870	-0.13297	0.849	0.682
hematology	hemoglobin concentration distribution width (HDW)	-0.042033	0.016231	-1.1445	0.152	0.0158
hematology	large unstained cells (percent of total WBC)	0.11225	0.12920	0.73404	0.713	0.394
hematology	lymphocyte differential (percent of total WBC)	1.1245	1.1602	0.41479	0.593	0.342
hematology	mean corpuscular hemoglobin (CHr)	0.013033	0.040622	0.13382	0.884	0.751
hematology	mean platelet volume (MPV)	0.12710	0.19332	0.62827	0.725	0.517
hematology	mean RBC corpuscular hemoglobin (MCH)	0.69490	0.82812	1.8062	0.750	0.409
hematology	mean RBC corpuscular hemoglobin concentration (MCHC)	1.4799	1.8437	1.8881	0.754	0.430
hematology	mean RBC corpuscular volume (MCV)	0.43668	0.32936	0.76756	0.404	0.197
hematology	measured hemoglobin (mHGB)	0.65408	0.85585	1.4261	0.707	0.452
hematology	monocyte differential (percent of total WBC)	-0.26387	0.15098	-0.64813	0.420	0.0928
hematology	neutrophil differential (percent of total WBC)	-0.64218	0.95625	-0.29536	0.712	0.508
hematology	platelet count (PLT; units per volume x 10³)	35.315	35.871	0.53415	0.683	0.334
hematology	RBC corpuscular distribution width (RDW)	-0.046739	0.073701	-0.15341	0.740	0.532
hematology	RBC corpuscular hemoglobin concentration mean (CHCM)	-0.29032	0.22873	-0.79062	0.472	0.216
hematology	red blood cell count (RBC; per volume x 10⁶)	0.019864	0.13125	-0.28000	0.945	0.881
hematology	reticulocyte count (Retic; units per volume x 10⁹)	16.968	12.689	0.78428	0.593	0.193
hematology	reticulocyte differential (percent of total RBC)	0.16537	0.10698	0.85881	0.473	0.135
hematology	white blood cell count (WBC; units per volume x 10³)	-0.99500	0.65777	-0.52471	0.321	0.143
holeboard	number of hole pokes by individual hole number, 20 min test, 1	-0.70979	0.47469	-0.66446	0.643	0.142
holeboard	number of hole pokes by individual hole number, 20 min test, 2	-0.25632	0.32177	-0.27257	0.833	0.430
holeboard	number of hole pokes by individual hole number, 20 min test, 3	-0.29038	0.25024	-0.41596	0.749	0.252
holeboard	number of hole pokes by individual hole number, 20 min test, 4	-0.11790	0.41154	-0.022790	0.931	0.776
holeboard	number of hole pokes by individual hole number, 20 min test, 5	-0.0038599	0.28612	0.11079	0.994	0.989
holeboard	number of hole pokes by individual hole number, 20 min test, 6	-0.74755	0.28960	-1.9853	0.384	0.0133
holeboard	number of hole pokes by individual hole number, 20 min test, 7	-0.40321	0.21068	-1.1289	0.689	0.0623
holeboard	number of hole pokes by individual hole number, 20 min test, 8	-0.86337	0.40507	-1.3109	0.484	0.0388
holeboard	number of hole pokes by individual hole number, 20 min test, 9	-1.0916	0.29648	-1.7155	0.0799	0.000642
holeboard	number of hole pokes by individual hole number, 20 min test, 10	-0.35615	0.22868	-0.98101	0.728	0.127
holeboard	number of hole pokes by individual hole number, 20 min test, 11	-0.029052	0.24442	-0.057461	0.979	0.906
holeboard	number of hole pokes by individual hole number, 20 min test, 12	-0.23912	0.41825	-0.31908	0.898	0.570
holeboard	number of hole pokes by individual hole number, 20 min test, 13	-1.3422	0.69522	-1.2537	0.420	0.0601
holeboard	number of hole pokes by individual hole number, 20 min test, 14	0.058902	0.37635	0.18835	0.981	0.876
holeboard	number of hole pokes by individual hole number, 20 min test, 15	-0.46600	0.38745	-0.66289	0.683	0.236
holeboard	number of hole pokes by individual hole number, 20 min test, 16	-0.80753	0.66130	-0.67767	0.644	0.229
holeboard	total number of hole pokes, 20 min test	-7.5018	3.2732	-0.99934	0.179	0.0269
light / dark	fecal boli count, 20 min test	0.15276	0.60363	0.18561	0.930	0.801
light / dark	latency to enter dark zone, 20 min test	112.97	46.339	1.7094	0.269	0.0185
light / dark	number of transitions between light and dark zones, 20 min test	1.8179	7.1128	0.27659	0.916	0.799
light / dark	percentage of total time in dark zone, 20 min test	-9.6074	5.2346	-1.5650	0.385	0.0725
light / dark	percentage of total time in light zone, 20 min test	9.6074	5.2346	1.5650	0.382	0.0725
light / dark	time mobile in dark zone, 20 min test	-22.516	10.498	-1.3304	0.196	0.0370
light / dark	time mobile in light zone, 20 min test	25.362	13.198	1.1290	0.244	0.0605
light / dark	time spent in dark zone, 20 min test	-157.20	66.348	-1.8398	0.249	0.0219
light / dark	time spent in light zone, 20 min test	157.20	66.348	1.8398	0.249	0.0219
open field	average speed in center of arena, 20 min test	-0.26020	0.36564	-0.56190	0.781	0.480
open field	average speed in periphery of arena, 20 min test	0.15292	0.13967	0.10019	0.505	0.279
open field	distance traveled habituation ratio, 20 min test	12.903	6.5894	1.0320	0.284	0.0559
open field	distance traveled in center of arena, 20 min test	72.683	104.06	0.12316	0.707	0.488
open field	distance traveled in periphery of arena, 20 min test	116.75	119.23	0.054402	0.575	0.332
open field	distance traveled slope, 20 min test	14.473	6.2155	1.2537	0.193	0.0241
open field	distance traveled, 20 min test, 1st 5min	1.7450	68.083	-0.33156	0.989	0.980
open field	distance traveled, 20 min test, 2nd 5min	-11.757	46.776	-0.64404	0.908	0.803
open field	distance traveled, 20 min test, 3rd 5min	66.215	53.641	0.29489	0.462	0.223
open field	distance traveled, 20 min test, 4th 5min	117.29	48.181	0.78444	0.106	0.0186
open field	number of clockwise revolution episodes, 20 min test	0.53020	1.1562	-0.094171	0.871	0.649
open field	number of counter-clockwise revolution episodes, 20 min test	0.44490	1.1034	-0.21169	0.849	0.689
open field	number of fecal boli, 20 min test	-0.90989	0.67094	-0.45932	0.509	0.182
open field	number of rears in 5 min bins, 20 min test, 1st 5min	-2.2408	2.1614	-0.81737	0.570	0.305
open field	number of rears in 5 min bins, 20 min test, 2nd 5min	-1.3828	2.1854	-0.70472	0.759	0.530
open field	number of rears in 5 min bins, 20 min test, 3rd 5min	-3.8111	2.5073	-1.2051	0.391	0.135
open field	number of rears in 5 min bins, 20 min test, 4th 5min	-0.95802	2.8283	-0.55876	0.875	0.736
open field	percentage of total time in center of arena, 20 min test	2.5994	2.8464	0.38019	0.678	0.366
open field	percentage of total time in center of arena, slope, 20 min test	1.6748	1.8308	1.0551	0.801	0.365
open field	percentage of total time in center, habituation ratio, 20 min test	1.5375	2.0111	0.94236	0.844	0.448
open field	percentage of total time in corners of arena, 20 min test	-4.7742	2.9451	-0.58883	0.410	0.111
open field	percentage of total time in corners, habituation ratio, 20 min test	-1.6251	1.7031	-1.0388	0.807	0.345
open field	percentage of total time in corners, slope, 20 min test	-1.0782	1.5849	-0.82151	0.885	0.500
open field	permanence time in center of arena, 20 min test	31.184	34.156	0.38019	0.678	0.366
open field	permanence time in corners of arena, 20 min test	-57.308	35.344	-0.58883	0.410	0.111
open field	permanence time in periphery of arena, 20 min test	-31.202	34.157	-0.38019	0.678	0.365
open field	total distance traveled, 20 min test	169.47	187.43	0.030213	0.593	0.370
open field	total number of rears, 20 min test	-8.4640	8.1094	-0.94027	0.557	0.302
open field	whole arena average speed, 20 min test	0.14260	0.15623	0.036930	0.588	0.366
open field	whole arena resting time, 20 min test	-26.877	18.400	-0.21306	0.325	0.150
open field	whole arena time spent mobile, 20 min test	26.877	18.393	0.46836	0.330	0.150
open field	whole arena time spent vertical, 20 min test	-10.492	7.7995	-0.91958	0.487	0.185
SHIRPA	locomotor activity (number of squares in the arena the mouse moves into with all four paws in first 30 s of test)	0.98176	1.5303	0.60266	0.773	0.526
startle / PPI	average baseline movement during background noise	-0.27544	0.91197	-0.12997	0.958	0.765
startle / PPI	average of each corrected maximum percent pre-pulse inhibition value	1.5665	0.47151	2.6595	0.0941	0.00242
startle / PPI	average of each corrected percent pre-pulse inhibition value	0.047659	0.064054	0.40420	0.772	0.463
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	13.498	10.111	1.5852	0.851	0.192
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-0.58500	6.2695	-0.10457	0.977	0.926
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	0.85302	4.9229	-0.013311	0.945	0.864
startle / PPI	average startle response to full pulse (120 dB)	-48.535	34.319	-0.67141	0.388	0.168
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-69.538	31.190	-1.0277	0.139	0.0340
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-32.647	23.877	-0.47942	0.392	0.182
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-24.158	18.856	-0.39310	0.423	0.210
startle / PPI	average startle response to pre-pulse, 74dB sound pressure level	-1.3940	1.4208	-0.93910	0.808	0.335
startle / PPI	average startle response to pre-pulse, 78dB sound pressure level	-2.5463	1.1579	-1.5755	0.447	0.0360
startle / PPI	average startle response to pre-pulse, 82dB sound pressure level	0.14796	2.1824	-0.10176	0.989	0.946
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	0.12354	0.12190	1.1882	0.869	0.319
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-0.015697	0.073589	-0.23860	0.956	0.833
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	0.035136	0.063110	0.12368	0.792	0.582
startle / PPI	corrected average startle response to full pulse (120 dB) minus average baseline movement during background noise	-48.312	34.398	-0.66092	0.393	0.171
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 74dB sound pressure level	-68.129	30.989	-0.99962	0.143	0.0363
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 78dB sound pressure level	-30.106	23.818	-0.42970	0.431	0.217
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 82dB sound pressure level	-24.305	19.244	-0.38253	0.429	0.217
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	2.1452	0.51695	3.2590	0.113	0.000266
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	1.6401	0.57235	2.9331	0.153	0.00767
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	0.91745	0.36833	2.3915	0.123	0.0189
startle / PPI	corrected maximum startle response to full pulse (120 dB) minus maximum baseline movement during background noise	-171.97	125.15	-0.65744	0.402	0.180
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 74dB sound pressure level	-252.28	115.71	-1.0301	0.143	0.0378
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 78dB sound pressure level	-114.70	92.651	-0.44203	0.441	0.226
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 82dB sound pressure level	-92.579	72.402	-0.38706	0.419	0.211
startle / PPI	maximum baseline movement during background noise	-0.43148	1.9466	-0.014712	0.964	0.826
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	15.687	11.368	1.6695	0.884	0.178
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	11.777	6.5029	1.0206	0.398	0.0805
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	21.842	6.7249	1.9032	0.0578	0.00293
startle / PPI	maximum startle response to full pulse (120 dB)	-172.20	124.85	-0.65223	0.400	0.179
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-255.43	115.66	-1.0616	0.137	0.0356
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-121.85	92.533	-0.48257	0.411	0.198
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-93.759	71.270	-0.41133	0.409	0.199
startle / PPI	maximum startle response to pre-pulse, 74dB sound pressure level	-3.1169	3.4687	-0.86135	0.791	0.376
startle / PPI	maximum startle response to pre-pulse, 78dB sound pressure level	-7.1509	2.6994	-1.7811	0.332	0.0129
startle / PPI	maximum startle response to pre-pulse, 82dB sound pressure level	-1.2617	5.0849	-0.44203	0.933	0.806

MULTIPLE (CATEGORICAL) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

Procedure	JaxKOMP-EAP Trait	Trait Effect	P-value
eye morphology	anterior chamber depth	1.0 %	1.0
eye morphology	bulging eye	1.0 %	1.00
eye morphology	cornea	3.0 %	1.00
eye morphology	cornea opacity	3.0 %	1.0
eye morphology	cornea vascularization	2.0 %	1.0
eye morphology	corneal deposits	1.0 %	1.00
eye morphology	corneal mineralization	1.0 %	1.00
eye morphology	corneal scleralization	2.0 %	1.0
eye morphology	corneal ulcer	1.0 %	1.00
eye morphology	eye closure	1.0 %	1.00
eye morphology	eye hemorrhage or blood presence	1.0 %	1.0
eye morphology	eyelid morphology	1.0 %	1.00
eye morphology	eyes (present, absent)	0.0 %	1.00
eye morphology	fusion between cornea and lens	3.0 %	1.0
eye morphology	iris pigmentation	2.0 %	1.0
eye morphology	iris transillumination	1.0 %	1.0
eye morphology	irispupil	3.0 %	1.0
eye morphology	lacrimation	3.0 %	1.00
eye morphology	lens	9.0 %	1.00
eye morphology	lens opacity	7.0 %	1.00
eye morphology	narrow eye opening	1.0 %	1.00
eye morphology	optic disc	3.0 %	1.0
eye morphology	persistence of hyaloid vascular system	9.0 %	1.00
eye morphology	pupil dilation	2.0 %	1.00
eye morphology	pupil light response	2.0 %	1.0
eye morphology	pupil position	4.0 %	1.0
eye morphology	pupil shape	3.0 %	1.0
eye morphology	retina	10.0 %	0.486
eye morphology	retinal blood vessels	3.0 %	1.00
eye morphology	retinal blood vessels pattern	4.0 %	1.00
eye morphology	retinal blood vessels structure	3.0 %	1.0
eye morphology	retinal pigmentation	10.0 %	0.618
eye morphology	retinal structure	3.0 %	1.0
eye morphology	synechia	3.0 %	1.00
eye morphology	vitreous	3.0 %	1.0
SHIRPA	activity body position	1.0 %	1.00
SHIRPA	aggression	1.0 %	1.0
SHIRPA	body length	0.0 %	1.00
SHIRPA	body position	0.0 %	1.0
SHIRPA	body thickness	0.0 %	1.0
SHIRPA	coat color abdomen	4.0 %	1.0
SHIRPA	coat color back	0.0 %	1.00
SHIRPA	coat color head	0.0 %	1.0
SHIRPA	coat color pattern abdomen	1.0 %	1.0
SHIRPA	coat color pattern back	0.0 %	1.0
SHIRPA	coat color pattern head	0.0 %	1.00
SHIRPA	coat hair abdomen texture appearance	2.0 %	1.0
SHIRPA	coat hair back texture appearance	0.0 %	1.0
SHIRPA	coat hair distribution abdomen	1.0 %	1.00
SHIRPA	coat hair distribution back	0.0 %	1.0
SHIRPA	coat hair distribution head	1.0 %	1.0
SHIRPA	coat hair head texture appearance	0.0 %	1.0
SHIRPA	contact righting	5.0 %	1.00
SHIRPA	ear morphology	0.0 %	1.0
SHIRPA	fat distribution	0.0 %	1.00
SHIRPA	forelimb digit number	0.0 %	1.00
SHIRPA	forelimb digit position	0.0 %	1.0
SHIRPA	forelimb digit shape	0.0 %	1.0
SHIRPA	forelimb digit size	0.0 %	1.0
SHIRPA	forelimb footpads	0.0 %	1.0
SHIRPA	forelimb nail length	0.0 %	1.0
SHIRPA	forelimb nail number	0.0 %	1.0
SHIRPA	forelimb nail position	0.0 %	1.0
SHIRPA	forelimb nail shape	0.0 %	1.0
SHIRPA	forelimbs position	0.0 %	1.0
SHIRPA	forelimbs shape	0.0 %	1.0
SHIRPA	forelimbs size	0.0 %	1.0
SHIRPA	forepaw position	0.0 %	1.0
SHIRPA	forepaw shape	0.0 %	1.0
SHIRPA	forepaw size	0.0 %	1.0
SHIRPA	gait (fluidity)	0.0 %	1.00
SHIRPA	genitalia morphology	0.0 %	1.00
SHIRPA	genitalia presence	0.0 %	1.0
SHIRPA	genitalia size	0.0 %	1.0
SHIRPA	head bobbing	0.0 %	1.0
SHIRPA	head morphology	0.0 %	1.0
SHIRPA	head size	0.0 %	1.00
SHIRPA	hindlimb digit number	0.0 %	1.00
SHIRPA	hindlimb digit position	0.0 %	1.0
SHIRPA	hindlimb digit shape	0.0 %	1.0
SHIRPA	hindlimb digit size	0.0 %	1.00
SHIRPA	hindlimb nail length	0.0 %	1.00
SHIRPA	hindlimb nail number	0.0 %	1.00
SHIRPA	hindlimb nail position	0.0 %	1.0
SHIRPA	hindlimb nail shape	0.0 %	1.0
SHIRPA	hindlimbs footpads	0.0 %	1.0
SHIRPA	hindlimbs position	0.0 %	1.0
SHIRPA	hindlimbs shape	0.0 %	1.0
SHIRPA	hindlimbs size	0.0 %	1.0
SHIRPA	hindpaw position	0.0 %	1.0
SHIRPA	hindpaw shape	0.0 %	1.0
SHIRPA	hindpaw size	0.0 %	1.0
SHIRPA	limb grasp	7.0 %	0.624
SHIRPA	lower lip morphology	0.0 %	1.0
SHIRPA	lower teeth appearance	0.0 %	1.00
SHIRPA	mouth morphology	0.0 %	1.00
SHIRPA	salivation	0.0 %	1.0
SHIRPA	skin color back paws	0.0 %	1.0
SHIRPA	skin color ear	0.0 %	1.0
SHIRPA	skin color front paws	0.0 %	1.0
SHIRPA	skin color snout	0.0 %	1.0
SHIRPA	skin color tail	0.0 %	1.0
SHIRPA	skin color whole body	0.0 %	1.0
SHIRPA	skin texture back paw	0.0 %	1.0
SHIRPA	skin texture ear	0.0 %	1.0
SHIRPA	skin texture front paws	0.0 %	1.0
SHIRPA	skin texture snout	0.0 %	1.0
SHIRPA	skin texture tail	0.0 %	1.0
SHIRPA	skin texture whole body	0.0 %	1.00
SHIRPA	snout size	0.0 %	1.0
SHIRPA	startle response	0.0 %	1.00
SHIRPA	tail curvature	0.0 %	1.0
SHIRPA	tail elevation	36.0 %	1.01e-7
SHIRPA	tail length	0.0 %	1.00
SHIRPA	tail morphology	0.0 %	1.00
SHIRPA	tail presence	0.0 %	1.0
SHIRPA	tail shape	0.0 %	1.00
SHIRPA	tail thickness	0.0 %	1.0
SHIRPA	teeth presence	0.0 %	1.00
SHIRPA	transfer arousal	1.0 %	1.0
SHIRPA	tremor	0.0 %	1.00
SHIRPA	trunk curl	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	0.0 %	1.00
SHIRPA	upper lip morphology	0.0 %	1.0
SHIRPA	upper teeth appearance	0.0 %	1.00
SHIRPA	vibrissae appearance	1.0 %	1.0
SHIRPA	vibrissae presence	2.0 %	1.0
SHIRPA	vocalization	2.0 %	1.00

GENOTYPE CORRELATION PLOT

Correlate Nars2^em1(IMPC)J -/+ with genotype:

This genotype correlation visualization can include both EAP and LAP measures.