MPD: JaxKOMP-EAP genotype: Myo1d<sup>em1(IMPC)J</sup> -/-

JaxKOMP-EAP effect sizes: Myo1d^em1(IMPC)J -/- Gene Myo1d

MULTIPLE (NUMERIC) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

Procedure	JaxKOMP-EAP Trait	Trait Effect	Trait Effect SE	Trait Effect RankZ	Adjusted p-value	Unadjusted p-value
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 6 kHz pip	3.1021	3.1871	0.65651	0.830	0.509
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 12 kHz pip	19.516	19.774	2.1347	0.841	0.504
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 18 kHz pip	50.172	24.799	2.7065	0.648	0.292
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 24 kHz pip	12.298	9.3363	1.6617	0.748	0.413
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 30 kHz pip	14.125	4.9023	1.9477	0.604	0.213
body composition	body length	0.024441	0.042551	0.55859	0.795	0.569
body composition	body weight (at time of DXA)	-1.8872	0.46965	-1.1520	0.00358	0.000252
body composition	bone area, whole body scan, head excluded	-0.13556	0.17274	-0.36131	0.688	0.437
body composition	bone mineral content of whole body scan, head excluded	-0.023406	0.012835	-1.0634	0.276	0.0759
body composition	bone mineral content to body weight ratio	-0.00073390	0.00043557	-0.75197	0.313	0.0998
body composition	bone mineral density of whole body scan, head excluded	-0.0018521	0.00063184	-1.7045	0.0716	0.00562
body composition	fat tissue mass of whole body scan, head excluded	-0.46259	0.30191	-0.86958	0.352	0.134
body composition	fat tissue mass to body weight ratio	-0.019881	0.010646	-0.89578	0.222	0.0694
body composition	lean tissue mass of whole body scan, head excluded	0.88979	0.27404	1.4902	0.0495	0.00240
body composition	lean tissue mass to body weight ratio	0.035548	0.0087683	1.7045	0.0101	0.000226
body composition	percent fat, whole body scan, head excluded	-2.2681	1.0255	-1.0977	0.148	0.0329
body composition	ratio of soft-tissue attenuation coefficients	0.0025575	0.0011487	1.1165	0.146	0.0318
body composition	tissue area	-0.25260	0.23064	-0.66508	0.582	0.280
body composition	total tissue mass, whole body scan, head excluded	0.43377	0.19324	0.69694	0.150	0.0305
clinical blood chemistry	alanine transaminase (plasma ALT)	2.8829	6.3730	0.24984	0.895	0.656
clinical blood chemistry	albumin (plasma Alb)	-1.1529	1.2189	-1.4309	0.663	0.355
clinical blood chemistry	alkaline phosphatase (plasma ALP)	15.149	5.1718	1.6257	0.0582	0.00777
clinical blood chemistry	aspartate transaminase (plasma AST)	15.133	42.895	0.61172	0.910	0.728
clinical blood chemistry	aspartate transaminase to alanine transaminase ratio (plasma AST:ALT)	0.56010	0.34760	1.4535	0.499	0.121
clinical blood chemistry	blood urea nitrogen (BUN)	-0.59908	2.1380	-0.26016	0.920	0.826
clinical blood chemistry	calcium (plasma Ca)	-0.22153	0.15306	-1.2446	0.394	0.171
clinical blood chemistry	creatinine (plasma)	-0.080192	0.018951	-1.4874	0.367	0.148
clinical blood chemistry	glucose (plasma GLU, no fast)	-12.816	21.985	-0.21079	0.811	0.664
clinical blood chemistry	HDL cholesterol (plasma HDL)	-4.5947	3.1918	-1.2621	0.445	0.166
clinical blood chemistry	HDL cholesterol to total cholesterol ratio	0.0059169	0.025237	0.19118	0.962	0.853
clinical blood chemistry	phosphorus (plasma phosphate)	0.55670	0.59963	0.78955	0.771	0.524
clinical blood chemistry	total bilirubin (plasma TBIL)	-0.047105	0.014641	-2.3406	0.0694	0.00432
clinical blood chemistry	total cholesterol (plasma CHOL, no fast)	11.059	6.3770	1.4608	0.641	0.333
clinical blood chemistry	triglyceride (plasma TG, no fast)	20.410	13.227	1.2077	0.645	0.366
EKG	duration of PQ interval	-0.93496	0.65358	-0.83532	0.734	0.160
EKG	duration of PR interval	-0.82006	0.65298	-0.70258	0.764	0.216
EKG	duration of QRS interval	-0.067060	0.32689	-0.32182	0.988	0.839
EKG	duration of QT interval	-0.41632	0.70588	-0.22143	0.898	0.559
EKG	duration of QTC interval, calculated by dividing QT interval by square root of preceding RR interval	-0.11638	0.72990	-0.082708	0.991	0.874
EKG	duration of RR interval	-2.3592	0.97920	-0.94619	0.315	0.0208
EKG	duration of ST interval	-0.52227	0.71559	-0.29435	0.861	0.470
EKG	heart rate coefficient of variation (signal intensity)	-0.99629	1.1003	-0.73916	0.867	0.371
EKG	heart rate variability, mean of differences between sequential beats; beats per min	-7.5672	7.9521	-0.82678	0.853	0.347
EKG	heart rate, beats per min	19.844	7.8505	0.97767	0.240	0.0156
EKG	mean R amplitude, mean amplitude of signal measured from isoelectric line to peak of QRS	0.15593	0.087105	1.0732	0.391	0.0810
EKG	mean SR amplitude, mean amplitude of signal measured from signal minimum line to peak of QRS	0.22945	0.10956	1.2383	0.290	0.0426
EKG	number of signals	-1.1593	3.6072	-0.28385	0.948	0.750
EKG	proportion of number pairs of successive beat-to-beat intervals that exceed 50 ms	-3.5307	2.3835	-0.57553	0.799	0.147
EKG	QT dispersion, measured as inter-lead variability of QT intervals	-1.1679	3.9212	-0.31758	0.971	0.767
EKG	QTc dispersion, calculated as rate-corrected QT dispersion	-1.3430	4.2880	-0.34953	0.966	0.756
EKG	root mean square of successive differences of neighboring RR intervals	-1.8543	2.3489	-0.93365	0.884	0.434
glucose tolerance test	amount glucose injected	-6.0770	4.5547	-1.2983	0.582	0.205
glucose tolerance test	plasma glucose, 0min	19.612	7.3430	1.5857	0.0851	0.0183
glucose tolerance test	plasma glucose, 15min	87.941	32.109	2.1758	0.148	0.0160
glucose tolerance test	plasma glucose, 30min	5.8286	27.137	0.31107	0.933	0.833
glucose tolerance test	plasma glucose, 60min	40.988	24.820	1.6204	0.406	0.121
glucose tolerance test	plasma glucose, 120min	17.071	11.848	0.99482	0.483	0.172
grip strength	body weight (at time of grip strength test)	-2.3738	0.40467	-1.6359	0.000105	0.00000348
grip strength	forelimb and hindlimb grip strength (mean of trials), average	-25.061	10.016	-1.4925	0.0847	0.0193
grip strength	forelimb and hindlimb grip strength (mean of trials), average normalized to bw	-0.70124	0.36728	-0.81745	0.203	0.0673
grip strength	forelimb and hindlimb grip strength by trial, trial1	-30.310	11.900	-1.6637	0.120	0.0174
grip strength	forelimb and hindlimb grip strength by trial, trial2	-12.360	10.961	-0.53912	0.525	0.270
grip strength	forelimb and hindlimb grip strength by trial, trial3	-29.933	12.509	-1.6136	0.141	0.0245
grip strength	forelimb grip strength (mean of trials), average	-2.3104	7.0668	-0.039222	0.886	0.746
grip strength	forelimb grip strength (mean of trials), average normalized to bw	-0.16259	0.24209	-0.19141	0.754	0.508
grip strength	forelimb grip strength by trial, trial1	-0.56353	8.0172	0.21513	0.981	0.945
grip strength	forelimb grip strength by trial, trial2	-16.281	5.7503	-1.4252	0.104	0.00883
grip strength	forelimb grip strength by trial, trial3	4.0804	7.9889	0.68088	0.837	0.614
heart weight	heart weight, normalized to body weight	-0.15932	0.18130	-1.0772	0.600	0.387
heart weight	heart weight, weight	-6.8411	3.8952	-1.3177	0.251	0.0889
hematology	basophil differential (percent of total WBC)	0.10655	0.053185	1.3694	0.416	0.0582
hematology	calculated hemoglobin (cHGB)	-0.24317	0.24744	-0.97113	0.613	0.337
hematology	eosinophil differential (percent of total WBC)	-1.2943	0.25014	-2.5821	0.00634	0.0000346
hematology	hematocrit (HCT)	-0.54428	0.53643	-0.87681	0.608	0.322
hematology	hemoglobin concentration distribution width (HDW)	-0.047957	0.018293	-1.2784	0.151	0.0156
hematology	large unstained cells (percent of total WBC)	-0.046335	0.15583	-0.29883	0.904	0.769
hematology	lymphocyte differential (percent of total WBC)	0.45964	0.99207	0.15921	0.814	0.648
hematology	mean corpuscular hemoglobin (CHr)	-0.16190	0.089848	-1.2638	0.258	0.0859
hematology	mean platelet volume (MPV)	-0.089040	0.091037	-0.76104	0.569	0.339
hematology	mean RBC corpuscular hemoglobin (MCH)	0.24701	0.12572	0.92073	0.330	0.0622
hematology	mean RBC corpuscular hemoglobin concentration (MCHC)	0.021369	0.35723	0.058933	0.982	0.953
hematology	mean RBC corpuscular volume (MCV)	-0.017657	0.33278	-0.030073	0.980	0.958
hematology	measured hemoglobin (mHGB)	0.022440	0.23651	-0.17386	0.973	0.925
hematology	monocyte differential (percent of total WBC)	-0.39181	0.21098	-0.94085	0.381	0.0767
hematology	neutrophil differential (percent of total WBC)	0.57501	0.91653	0.31253	0.734	0.537
hematology	platelet count (PLT; units per volume x 10³)	-18.575	53.105	-0.20507	0.897	0.730
hematology	RBC corpuscular distribution width (RDW)	-0.052924	0.079833	-0.17564	0.729	0.514
hematology	RBC corpuscular hemoglobin concentration mean (CHCM)	-0.45823	0.17732	-1.2061	0.0983	0.0169
hematology	red blood cell count (RBC; per volume x 10⁶)	-0.060097	0.16621	-0.59743	0.874	0.721
hematology	reticulocyte count (Retic; units per volume x 10⁹)	-44.832	16.568	-1.6000	0.209	0.0132
hematology	reticulocyte differential (percent of total RBC)	-0.46069	0.17037	-1.5573	0.206	0.0133
hematology	white blood cell count (WBC; units per volume x 10³)	1.4827	1.2041	1.1644	0.437	0.231
holeboard	number of hole pokes by individual hole number, 20 min test, 1	1.4211	0.68036	1.2758	0.460	0.0441
holeboard	number of hole pokes by individual hole number, 20 min test, 2	0.10009	0.36359	0.30601	0.960	0.785
holeboard	number of hole pokes by individual hole number, 20 min test, 3	0.18987	0.40520	0.39215	0.926	0.642
holeboard	number of hole pokes by individual hole number, 20 min test, 4	1.9019	0.52847	1.7232	0.110	0.000978
holeboard	number of hole pokes by individual hole number, 20 min test, 5	0.20750	0.35363	0.44187	0.893	0.561
holeboard	number of hole pokes by individual hole number, 20 min test, 6	0.10550	0.24282	0.33332	0.945	0.667
holeboard	number of hole pokes by individual hole number, 20 min test, 7	-0.10300	0.19684	-0.30113	0.949	0.604
holeboard	number of hole pokes by individual hole number, 20 min test, 8	-0.75325	0.34433	-1.1362	0.471	0.0355
holeboard	number of hole pokes by individual hole number, 20 min test, 9	0.27750	0.36981	0.59393	0.863	0.458
holeboard	number of hole pokes by individual hole number, 20 min test, 10	0.095500	0.19533	0.31819	0.939	0.628
holeboard	number of hole pokes by individual hole number, 20 min test, 11	0.17880	0.29700	0.47313	0.899	0.551
holeboard	number of hole pokes by individual hole number, 20 min test, 12	-0.78800	0.43325	-1.2069	0.512	0.0773
holeboard	number of hole pokes by individual hole number, 20 min test, 13	0.62556	0.76891	0.71420	0.770	0.421
holeboard	number of hole pokes by individual hole number, 20 min test, 14	-0.084209	0.40364	-0.064143	0.965	0.836
holeboard	number of hole pokes by individual hole number, 20 min test, 15	-0.018828	0.46112	0.072597	0.985	0.968
holeboard	number of hole pokes by individual hole number, 20 min test, 16	-1.6989	0.90462	-1.4659	0.448	0.0685
holeboard	total number of hole pokes, 20 min test	-0.17350	2.9946	0.064143	0.978	0.954
light / dark	fecal boli count, 20 min test	-1.0220	0.54139	-1.1484	0.424	0.0665
light / dark	latency to enter dark zone, 20 min test	-78.971	37.396	-1.5604	0.397	0.0412
light / dark	number of transitions between light and dark zones, 20 min test	5.8864	7.4147	0.63677	0.712	0.432
light / dark	percentage of total time in dark zone, 20 min test	-4.5130	3.8748	-0.69414	0.615	0.251
light / dark	percentage of total time in light zone, 20 min test	4.5130	3.8748	0.69242	0.616	0.251
light / dark	time mobile in dark zone, 20 min test	-11.500	11.633	-0.82024	0.621	0.329
light / dark	time mobile in light zone, 20 min test	8.7897	11.121	0.32754	0.689	0.434
light / dark	time spent in dark zone, 20 min test	10.848	45.632	0.38663	0.948	0.813
light / dark	time spent in light zone, 20 min test	-10.848	45.632	-0.38663	0.948	0.813
open field	average speed in center of arena, 20 min test	-0.20219	0.35446	-0.44156	0.818	0.572
open field	average speed in periphery of arena, 20 min test	0.11141	0.13452	-0.051713	0.633	0.412
open field	distance traveled habituation ratio, 20 min test	-4.4488	6.9007	-0.34292	0.769	0.523
open field	distance traveled in center of arena, 20 min test	151.35	75.270	0.59523	0.197	0.0510
open field	distance traveled in periphery of arena, 20 min test	-23.877	120.78	-0.54158	0.929	0.844
open field	distance traveled slope, 20 min test	-4.6113	6.4797	-0.36006	0.751	0.481
open field	distance traveled, 20 min test, 1st 5min	74.479	70.528	0.25030	0.543	0.297
open field	distance traveled, 20 min test, 2nd 5min	18.229	42.118	-0.29770	0.834	0.667
open field	distance traveled, 20 min test, 3rd 5min	0.020833	48.075	-0.42680	1.00	1.00
open field	distance traveled, 20 min test, 4th 5min	34.446	42.015	-0.059781	0.650	0.417
open field	number of clockwise revolution episodes, 20 min test	0.40417	0.89922	-0.17553	0.872	0.655
open field	number of counter-clockwise revolution episodes, 20 min test	1.2458	1.3660	0.24476	0.653	0.367
open field	number of fecal boli, 20 min test	-0.72500	0.95873	-0.30308	0.741	0.454
open field	number of rears in 5 min bins, 20 min test, 1st 5min	-3.3547	1.9673	-1.1153	0.316	0.0957
open field	number of rears in 5 min bins, 20 min test, 2nd 5min	-2.4833	2.5008	-0.96564	0.611	0.327
open field	number of rears in 5 min bins, 20 min test, 3rd 5min	4.1957	3.7974	0.66399	0.553	0.276
open field	number of rears in 5 min bins, 20 min test, 4th 5min	1.5161	3.5452	-0.010070	0.833	0.671
open field	percentage of total time in center of arena, 20 min test	6.4601	2.8685	1.2276	0.229	0.0297
open field	percentage of total time in center of arena, slope, 20 min test	2.1700	1.2385	1.3278	0.530	0.0872
open field	percentage of total time in center, habituation ratio, 20 min test	2.1056	1.2996	1.2655	0.560	0.113
open field	percentage of total time in corners of arena, 20 min test	-1.6447	4.5949	-0.0046991	0.891	0.722
open field	percentage of total time in corners, habituation ratio, 20 min test	-0.21754	1.3896	-0.39466	0.980	0.876
open field	percentage of total time in corners, slope, 20 min test	0.80742	1.3417	0.098842	0.897	0.551
open field	permanence time in center of arena, 20 min test	77.537	34.422	1.2276	0.230	0.0297
open field	permanence time in corners of arena, 20 min test	-19.738	55.137	-0.0046991	0.892	0.722
open field	permanence time in periphery of arena, 20 min test	-77.571	34.422	-1.2276	0.229	0.0296
open field	total distance traveled, 20 min test	127.47	171.03	-0.10694	0.675	0.460
open field	total number of rears, 20 min test	3.2155	11.053	-0.11505	0.893	0.773
open field	whole arena average speed, 20 min test	0.10796	0.14255	-0.10289	0.666	0.453
open field	whole arena resting time, 20 min test	-26.047	17.864	-0.19113	0.327	0.152
open field	whole arena time spent mobile, 20 min test	26.130	17.852	0.44156	0.330	0.151
open field	whole arena time spent vertical, 20 min test	-0.51815	11.373	-0.15434	0.988	0.964
SHIRPA	locomotor activity (number of squares in the arena the mouse moves into with all four paws in first 30 s of test)	-2.4418	1.7428	-0.85471	0.489	0.173
startle / PPI	average baseline movement during background noise	-1.4901	0.88856	-0.98814	0.625	0.104
startle / PPI	average of each corrected maximum percent pre-pulse inhibition value	-0.012620	0.35101	-0.19958	0.988	0.972
startle / PPI	average of each corrected percent pre-pulse inhibition value	0.16903	0.10962	1.5373	0.465	0.133
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	15.039	7.1909	1.7949	0.771	0.0448
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	17.271	7.0833	1.7743	0.252	0.0209
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	8.9925	6.0758	0.82536	0.423	0.149
startle / PPI	average startle response to full pulse (120 dB)	-142.74	25.056	-1.8947	0.000180	0.00000291
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-151.24	22.192	-2.0179	0.0000158	1.24e-7
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-120.56	18.233	-1.8237	0.0000311	2.18e-7
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-88.530	16.305	-1.5852	0.000386	0.00000627
startle / PPI	average startle response to pre-pulse, 74dB sound pressure level	0.22933	1.0527	0.23977	0.973	0.829
startle / PPI	average startle response to pre-pulse, 78dB sound pressure level	-0.86012	1.4375	-0.59437	0.903	0.554
startle / PPI	average startle response to pre-pulse, 82dB sound pressure level	-5.0339	1.4433	-2.2656	0.0827	0.00148
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	0.074401	0.18065	0.75267	0.932	0.683
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	0.17665	0.14609	1.4357	0.579	0.236
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	0.27468	0.085998	1.8309	0.0449	0.00321
startle / PPI	corrected average startle response to full pulse (120 dB) minus average baseline movement during background noise	-141.87	25.298	-1.8464	0.000204	0.00000376
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 74dB sound pressure level	-153.22	22.151	-2.0179	0.0000128	9.32e-8
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 78dB sound pressure level	-120.34	18.188	-1.7743	0.0000291	2.15e-7
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 82dB sound pressure level	-84.905	16.684	-1.5287	0.000763	0.0000166
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-0.20448	0.47254	-1.5470	0.940	0.668
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-0.074580	0.52929	-0.64659	0.957	0.889
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	0.23630	0.095085	1.4682	0.122	0.0186
startle / PPI	corrected maximum startle response to full pulse (120 dB) minus maximum baseline movement during background noise	-525.12	91.622	-1.9387	0.000169	0.00000264
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 74dB sound pressure level	-573.00	85.226	-2.1124	0.0000178	1.60e-7
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 78dB sound pressure level	-446.89	68.109	-1.8164	0.0000374	2.51e-7
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 82dB sound pressure level	-326.08	62.463	-1.5952	0.000583	0.0000114
startle / PPI	maximum baseline movement during background noise	-2.9278	2.5134	-0.80776	0.737	0.253
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	11.268	8.0302	1.1713	0.878	0.171
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	15.321	7.6569	1.3477	0.339	0.0542
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	11.461	6.9672	0.93259	0.364	0.110
startle / PPI	maximum startle response to full pulse (120 dB)	-525.58	90.922	-1.9387	0.000147	0.00000229
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-568.07	85.475	-2.0995	0.0000221	1.98e-7
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-449.45	67.582	-1.8312	0.0000292	1.96e-7
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-333.53	61.672	-1.6259	0.000419	0.00000666
startle / PPI	maximum startle response to pre-pulse, 74dB sound pressure level	0.52912	2.7635	0.29203	0.961	0.849
startle / PPI	maximum startle response to pre-pulse, 78dB sound pressure level	-5.8032	5.3461	-1.5287	0.758	0.286
startle / PPI	maximum startle response to pre-pulse, 82dB sound pressure level	-10.872	3.4491	-2.1392	0.107	0.00358

MULTIPLE (CATEGORICAL) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

Procedure	JaxKOMP-EAP Trait	Sex	Trait Effect	P-value
eye morphology	anterior chamber depth	females	1.0 %	1.0
eye morphology	anterior chamber depth	males	0.0 %	1.0
eye morphology	anterior chamber depth	both	1.0 %	1.0
eye morphology	bulging eye	females	1.0 %	1.0
eye morphology	bulging eye	males	0.0 %	1.0
eye morphology	bulging eye	both	1.0 %	1.0
eye morphology	cornea	females	4.0 %	1.0
eye morphology	cornea	males	2.0 %	1.0
eye morphology	cornea	both	3.0 %	1.0
eye morphology	cornea opacity	females	5.0 %	1.0
eye morphology	cornea opacity	males	1.0 %	1.0
eye morphology	cornea opacity	both	3.0 %	1.0
eye morphology	cornea vascularization	females	3.0 %	1.0
eye morphology	cornea vascularization	males	1.0 %	1.0
eye morphology	cornea vascularization	both	2.0 %	1.0
eye morphology	corneal deposits	females	2.0 %	1.0
eye morphology	corneal deposits	males	1.0 %	1.0
eye morphology	corneal deposits	both	1.0 %	1.0
eye morphology	corneal mineralization	females	2.0 %	1.0
eye morphology	corneal mineralization	males	1.0 %	1.0
eye morphology	corneal mineralization	both	1.0 %	1.00
eye morphology	corneal scleralization	females	3.0 %	1.0
eye morphology	corneal scleralization	males	1.0 %	1.0
eye morphology	corneal scleralization	both	2.0 %	1.0
eye morphology	corneal ulcer	females	1.0 %	1.0
eye morphology	corneal ulcer	males	1.0 %	1.0
eye morphology	corneal ulcer	both	1.0 %	1.00
eye morphology	eye closure	females	1.0 %	1.0
eye morphology	eye closure	males	0.0 %	1.0
eye morphology	eye closure	both	1.0 %	1.0
eye morphology	eye hemorrhage or blood presence	females	2.0 %	1.0
eye morphology	eye hemorrhage or blood presence	males	1.0 %	1.0
eye morphology	eye hemorrhage or blood presence	both	1.0 %	1.0
eye morphology	eyelid morphology	females	1.0 %	1.00
eye morphology	eyelid morphology	males	0.0 %	1.0
eye morphology	eyelid morphology	both	1.0 %	1.0
eye morphology	eyes (present, absent)	females	1.0 %	1.00
eye morphology	eyes (present, absent)	males	0.0 %	1.0
eye morphology	eyes (present, absent)	both	0.0 %	1.0
eye morphology	fusion between cornea and lens	females	4.0 %	1.0
eye morphology	fusion between cornea and lens	males	2.0 %	1.0
eye morphology	fusion between cornea and lens	both	3.0 %	1.0
eye morphology	iris pigmentation	females	2.0 %	1.0
eye morphology	iris pigmentation	males	1.0 %	1.0
eye morphology	iris pigmentation	both	2.0 %	1.0
eye morphology	iris transillumination	females	2.0 %	1.0
eye morphology	iris transillumination	males	1.0 %	1.00
eye morphology	iris transillumination	both	1.0 %	1.0
eye morphology	irispupil	females	4.0 %	1.0
eye morphology	irispupil	males	3.0 %	1.0
eye morphology	irispupil	both	3.0 %	1.0
eye morphology	lacrimation	females	3.0 %	1.0
eye morphology	lacrimation	males	2.0 %	1.0
eye morphology	lacrimation	both	3.0 %	1.00
eye morphology	lens	females	10.0 %	1.0
eye morphology	lens	males	8.0 %	1.00
eye morphology	lens	both	9.0 %	1.0
eye morphology	lens opacity	females	9.0 %	1.0
eye morphology	lens opacity	males	6.0 %	1.0
eye morphology	lens opacity	both	7.0 %	1.00
eye morphology	narrow eye opening	females	2.0 %	1.00
eye morphology	narrow eye opening	males	1.0 %	1.0
eye morphology	narrow eye opening	both	1.0 %	1.00
eye morphology	optic disc	females	4.0 %	1.0
eye morphology	optic disc	males	2.0 %	1.0
eye morphology	optic disc	both	3.0 %	1.0
eye morphology	persistence of hyaloid vascular system	females	14.0 %	1.0
eye morphology	persistence of hyaloid vascular system	males	5.0 %	1.0
eye morphology	persistence of hyaloid vascular system	both	9.0 %	1.0
eye morphology	pupil dilation	females	2.0 %	1.0
eye morphology	pupil dilation	males	1.0 %	1.0
eye morphology	pupil dilation	both	2.0 %	1.0
eye morphology	pupil light response	females	2.0 %	1.0
eye morphology	pupil light response	males	1.0 %	1.0
eye morphology	pupil light response	both	2.0 %	1.0
eye morphology	pupil position	females	4.0 %	1.0
eye morphology	pupil position	males	3.0 %	1.0
eye morphology	pupil position	both	4.0 %	1.0
eye morphology	pupil shape	females	3.0 %	1.0
eye morphology	pupil shape	males	2.0 %	1.0
eye morphology	pupil shape	both	3.0 %	1.0
eye morphology	retina	females	18.0 %	0.314
eye morphology	retina	males	51.0 %	0.0738
eye morphology	retina	both	25.0 %	0.0922
eye morphology	retinal blood vessels	females	4.0 %	1.0
eye morphology	retinal blood vessels	males	2.0 %	1.0
eye morphology	retinal blood vessels	both	3.0 %	1.0
eye morphology	retinal blood vessels pattern	females	5.0 %	1.0
eye morphology	retinal blood vessels pattern	males	2.0 %	1.00
eye morphology	retinal blood vessels pattern	both	4.0 %	1.0
eye morphology	retinal blood vessels structure	females	4.0 %	1.0
eye morphology	retinal blood vessels structure	males	2.0 %	1.0
eye morphology	retinal blood vessels structure	both	3.0 %	1.0
eye morphology	retinal pigmentation	females	18.0 %	0.363
eye morphology	retinal pigmentation	males	30.0 %	0.156
eye morphology	retinal pigmentation	both	22.0 %	0.109
eye morphology	retinal structure	females	4.0 %	1.0
eye morphology	retinal structure	males	2.0 %	1.00
eye morphology	retinal structure	both	3.0 %	1.0
eye morphology	synechia	females	4.0 %	1.0
eye morphology	synechia	males	2.0 %	1.0
eye morphology	synechia	both	3.0 %	1.00
eye morphology	vitreous	females	4.0 %	1.0
eye morphology	vitreous	males	2.0 %	1.0
eye morphology	vitreous	both	3.0 %	1.0
SHIRPA	activity body position	females	1.0 %	1.0
SHIRPA	activity body position	males	2.0 %	1.0
SHIRPA	activity body position	both	1.0 %	1.00
SHIRPA	aggression	females	0.0 %	1.00
SHIRPA	aggression	males	1.0 %	1.0
SHIRPA	aggression	both	1.0 %	1.0
SHIRPA	body length	females	0.0 %	1.0
SHIRPA	body length	males	0.0 %	1.00
SHIRPA	body length	both	0.0 %	1.00
SHIRPA	body position	females	0.0 %	1.0
SHIRPA	body position	males	1.0 %	1.0
SHIRPA	body position	both	0.0 %	1.0
SHIRPA	body thickness	females	1.0 %	1.0
SHIRPA	body thickness	males	0.0 %	1.0
SHIRPA	body thickness	both	0.0 %	1.0
SHIRPA	coat color abdomen	females	3.0 %	1.00
SHIRPA	coat color abdomen	males	4.0 %	1.0
SHIRPA	coat color abdomen	both	4.0 %	1.0
SHIRPA	coat color back	females	0.0 %	1.0
SHIRPA	coat color back	males	0.0 %	1.00
SHIRPA	coat color back	both	0.0 %	1.00
SHIRPA	coat color head	females	0.0 %	1.0
SHIRPA	coat color head	males	0.0 %	1.00
SHIRPA	coat color head	both	0.0 %	1.0
SHIRPA	coat color pattern abdomen	females	1.0 %	1.0
SHIRPA	coat color pattern abdomen	males	1.0 %	1.0
SHIRPA	coat color pattern abdomen	both	1.0 %	1.0
SHIRPA	coat color pattern back	females	0.0 %	1.0
SHIRPA	coat color pattern back	males	0.0 %	1.00
SHIRPA	coat color pattern back	both	0.0 %	1.0
SHIRPA	coat color pattern head	females	0.0 %	1.0
SHIRPA	coat color pattern head	males	0.0 %	1.0
SHIRPA	coat color pattern head	both	0.0 %	1.00
SHIRPA	coat hair abdomen texture appearance	females	2.0 %	1.0
SHIRPA	coat hair abdomen texture appearance	males	2.0 %	1.0
SHIRPA	coat hair abdomen texture appearance	both	2.0 %	1.0
SHIRPA	coat hair back texture appearance	females	0.0 %	1.0
SHIRPA	coat hair back texture appearance	males	0.0 %	1.0
SHIRPA	coat hair back texture appearance	both	0.0 %	1.0
SHIRPA	coat hair distribution abdomen	females	0.0 %	1.0
SHIRPA	coat hair distribution abdomen	males	1.0 %	1.00
SHIRPA	coat hair distribution abdomen	both	1.0 %	1.00
SHIRPA	coat hair distribution back	females	0.0 %	1.0
SHIRPA	coat hair distribution back	males	0.0 %	1.0
SHIRPA	coat hair distribution back	both	0.0 %	1.0
SHIRPA	coat hair distribution head	females	1.0 %	1.00
SHIRPA	coat hair distribution head	males	1.0 %	1.0
SHIRPA	coat hair distribution head	both	1.0 %	1.0
SHIRPA	coat hair head texture appearance	females	0.0 %	1.00
SHIRPA	coat hair head texture appearance	males	0.0 %	1.0
SHIRPA	coat hair head texture appearance	both	0.0 %	1.0
SHIRPA	contact righting	females	5.0 %	1.0
SHIRPA	contact righting	males	5.0 %	1.00
SHIRPA	contact righting	both	5.0 %	1.00
SHIRPA	ear morphology	females	0.0 %	1.0
SHIRPA	ear morphology	males	0.0 %	1.0
SHIRPA	ear morphology	both	0.0 %	1.0
SHIRPA	fat distribution	females	0.0 %	1.0
SHIRPA	fat distribution	males	0.0 %	1.0
SHIRPA	fat distribution	both	0.0 %	1.00
SHIRPA	forelimb digit number	females	0.0 %	1.00
SHIRPA	forelimb digit number	males	0.0 %	1.0
SHIRPA	forelimb digit number	both	0.0 %	1.00
SHIRPA	forelimb digit position	females	0.0 %	1.0
SHIRPA	forelimb digit position	males	0.0 %	1.0
SHIRPA	forelimb digit position	both	0.0 %	1.0
SHIRPA	forelimb digit shape	females	0.0 %	1.0
SHIRPA	forelimb digit shape	males	0.0 %	1.0
SHIRPA	forelimb digit shape	both	0.0 %	1.0
SHIRPA	forelimb digit size	females	0.0 %	1.0
SHIRPA	forelimb digit size	males	0.0 %	1.0
SHIRPA	forelimb digit size	both	0.0 %	1.0
SHIRPA	forelimb footpads	females	0.0 %	1.0
SHIRPA	forelimb footpads	males	0.0 %	1.0
SHIRPA	forelimb footpads	both	0.0 %	1.0
SHIRPA	forelimb nail length	females	0.0 %	1.0
SHIRPA	forelimb nail length	males	0.0 %	1.0
SHIRPA	forelimb nail length	both	0.0 %	1.0
SHIRPA	forelimb nail number	females	0.0 %	1.0
SHIRPA	forelimb nail number	males	0.0 %	1.0
SHIRPA	forelimb nail number	both	0.0 %	1.0
SHIRPA	forelimb nail position	females	0.0 %	1.0
SHIRPA	forelimb nail position	males	0.0 %	1.0
SHIRPA	forelimb nail position	both	0.0 %	1.0
SHIRPA	forelimb nail shape	females	0.0 %	1.0
SHIRPA	forelimb nail shape	males	0.0 %	1.0
SHIRPA	forelimb nail shape	both	0.0 %	1.0
SHIRPA	forelimbs position	females	0.0 %	1.0
SHIRPA	forelimbs position	males	0.0 %	1.0
SHIRPA	forelimbs position	both	0.0 %	1.0
SHIRPA	forelimbs shape	females	0.0 %	1.0
SHIRPA	forelimbs shape	males	0.0 %	1.0
SHIRPA	forelimbs shape	both	0.0 %	1.0
SHIRPA	forelimbs size	females	0.0 %	1.0
SHIRPA	forelimbs size	males	0.0 %	1.0
SHIRPA	forelimbs size	both	0.0 %	1.0
SHIRPA	forepaw position	females	0.0 %	1.0
SHIRPA	forepaw position	males	0.0 %	1.0
SHIRPA	forepaw position	both	0.0 %	1.0
SHIRPA	forepaw shape	females	0.0 %	1.0
SHIRPA	forepaw shape	males	0.0 %	1.0
SHIRPA	forepaw shape	both	0.0 %	1.0
SHIRPA	forepaw size	females	0.0 %	1.0
SHIRPA	forepaw size	males	0.0 %	1.0
SHIRPA	forepaw size	both	0.0 %	1.0
SHIRPA	gait (fluidity)	females	0.0 %	1.0
SHIRPA	gait (fluidity)	males	0.0 %	1.00
SHIRPA	gait (fluidity)	both	0.0 %	1.00
SHIRPA	genitalia morphology	females	0.0 %	1.00
SHIRPA	genitalia morphology	males	0.0 %	1.0
SHIRPA	genitalia morphology	both	0.0 %	1.00
SHIRPA	genitalia presence	females	0.0 %	1.0
SHIRPA	genitalia presence	males	0.0 %	1.0
SHIRPA	genitalia presence	both	0.0 %	1.0
SHIRPA	genitalia size	females	0.0 %	1.0
SHIRPA	genitalia size	males	0.0 %	1.0
SHIRPA	genitalia size	both	0.0 %	1.0
SHIRPA	head bobbing	females	0.0 %	1.0
SHIRPA	head bobbing	males	0.0 %	1.0
SHIRPA	head bobbing	both	0.0 %	1.0
SHIRPA	head morphology	females	0.0 %	1.0
SHIRPA	head morphology	males	0.0 %	1.00
SHIRPA	head morphology	both	0.0 %	1.0
SHIRPA	head size	females	0.0 %	1.0
SHIRPA	head size	males	0.0 %	1.0
SHIRPA	head size	both	0.0 %	1.00
SHIRPA	hindlimb digit number	females	1.0 %	1.00
SHIRPA	hindlimb digit number	males	0.0 %	1.0
SHIRPA	hindlimb digit number	both	0.0 %	1.00
SHIRPA	hindlimb digit position	females	0.0 %	1.0
SHIRPA	hindlimb digit position	males	0.0 %	1.0
SHIRPA	hindlimb digit position	both	0.0 %	1.0
SHIRPA	hindlimb digit shape	females	0.0 %	1.0
SHIRPA	hindlimb digit shape	males	0.0 %	1.0
SHIRPA	hindlimb digit shape	both	0.0 %	1.0
SHIRPA	hindlimb digit size	females	0.0 %	1.00
SHIRPA	hindlimb digit size	males	0.0 %	1.0
SHIRPA	hindlimb digit size	both	0.0 %	1.00
SHIRPA	hindlimb nail length	females	0.0 %	1.0
SHIRPA	hindlimb nail length	males	0.0 %	1.0
SHIRPA	hindlimb nail length	both	0.0 %	1.00
SHIRPA	hindlimb nail number	females	0.0 %	1.0
SHIRPA	hindlimb nail number	males	1.0 %	1.0
SHIRPA	hindlimb nail number	both	0.0 %	1.00
SHIRPA	hindlimb nail position	females	0.0 %	1.0
SHIRPA	hindlimb nail position	males	0.0 %	1.0
SHIRPA	hindlimb nail position	both	0.0 %	1.0
SHIRPA	hindlimb nail shape	females	0.0 %	1.0
SHIRPA	hindlimb nail shape	males	0.0 %	1.0
SHIRPA	hindlimb nail shape	both	0.0 %	1.0
SHIRPA	hindlimbs footpads	females	0.0 %	1.0
SHIRPA	hindlimbs footpads	males	0.0 %	1.0
SHIRPA	hindlimbs footpads	both	0.0 %	1.0
SHIRPA	hindlimbs position	females	0.0 %	1.0
SHIRPA	hindlimbs position	males	0.0 %	1.0
SHIRPA	hindlimbs position	both	0.0 %	1.0
SHIRPA	hindlimbs shape	females	0.0 %	1.0
SHIRPA	hindlimbs shape	males	0.0 %	1.0
SHIRPA	hindlimbs shape	both	0.0 %	1.0
SHIRPA	hindlimbs size	females	0.0 %	1.0
SHIRPA	hindlimbs size	males	0.0 %	1.0
SHIRPA	hindlimbs size	both	0.0 %	1.0
SHIRPA	hindpaw position	females	0.0 %	1.0
SHIRPA	hindpaw position	males	0.0 %	1.0
SHIRPA	hindpaw position	both	0.0 %	1.0
SHIRPA	hindpaw shape	females	0.0 %	1.0
SHIRPA	hindpaw shape	males	0.0 %	1.0
SHIRPA	hindpaw shape	both	0.0 %	1.0
SHIRPA	hindpaw size	females	0.0 %	1.0
SHIRPA	hindpaw size	males	0.0 %	1.0
SHIRPA	hindpaw size	both	0.0 %	1.0
SHIRPA	limb grasp	females	4.0 %	0.524
SHIRPA	limb grasp	males	6.0 %	1.0
SHIRPA	limb grasp	both	1.0 %	1.0
SHIRPA	lower lip morphology	females	0.0 %	1.0
SHIRPA	lower lip morphology	males	0.0 %	1.0
SHIRPA	lower lip morphology	both	0.0 %	1.0
SHIRPA	lower teeth appearance	females	0.0 %	1.0
SHIRPA	lower teeth appearance	males	0.0 %	1.00
SHIRPA	lower teeth appearance	both	0.0 %	1.00
SHIRPA	mouth morphology	females	0.0 %	1.0
SHIRPA	mouth morphology	males	0.0 %	1.00
SHIRPA	mouth morphology	both	0.0 %	1.00
SHIRPA	salivation	females	0.0 %	1.0
SHIRPA	salivation	males	0.0 %	1.0
SHIRPA	salivation	both	0.0 %	1.0
SHIRPA	skin color back paws	females	0.0 %	1.0
SHIRPA	skin color back paws	males	0.0 %	1.0
SHIRPA	skin color back paws	both	0.0 %	1.0
SHIRPA	skin color ear	females	0.0 %	1.0
SHIRPA	skin color ear	males	0.0 %	1.0
SHIRPA	skin color ear	both	0.0 %	1.0
SHIRPA	skin color front paws	females	0.0 %	1.0
SHIRPA	skin color front paws	males	0.0 %	1.0
SHIRPA	skin color front paws	both	0.0 %	1.0
SHIRPA	skin color snout	females	0.0 %	1.0
SHIRPA	skin color snout	males	0.0 %	1.0
SHIRPA	skin color snout	both	0.0 %	1.0
SHIRPA	skin color tail	females	0.0 %	1.0
SHIRPA	skin color tail	males	0.0 %	1.0
SHIRPA	skin color tail	both	0.0 %	1.0
SHIRPA	skin color whole body	females	0.0 %	1.0
SHIRPA	skin color whole body	males	0.0 %	1.0
SHIRPA	skin color whole body	both	0.0 %	1.0
SHIRPA	skin texture back paw	females	0.0 %	1.0
SHIRPA	skin texture back paw	males	0.0 %	1.0
SHIRPA	skin texture back paw	both	0.0 %	1.0
SHIRPA	skin texture ear	females	0.0 %	1.0
SHIRPA	skin texture ear	males	0.0 %	1.0
SHIRPA	skin texture ear	both	0.0 %	1.0
SHIRPA	skin texture front paws	females	0.0 %	1.0
SHIRPA	skin texture front paws	males	0.0 %	1.0
SHIRPA	skin texture front paws	both	0.0 %	1.0
SHIRPA	skin texture snout	females	0.0 %	1.0
SHIRPA	skin texture snout	males	0.0 %	1.0
SHIRPA	skin texture snout	both	0.0 %	1.0
SHIRPA	skin texture tail	females	0.0 %	1.0
SHIRPA	skin texture tail	males	0.0 %	1.0
SHIRPA	skin texture tail	both	0.0 %	1.0
SHIRPA	skin texture whole body	females	0.0 %	1.0
SHIRPA	skin texture whole body	males	0.0 %	1.00
SHIRPA	skin texture whole body	both	0.0 %	1.00
SHIRPA	snout size	females	0.0 %	1.0
SHIRPA	snout size	males	1.0 %	1.0
SHIRPA	snout size	both	0.0 %	1.0
SHIRPA	startle response	females	25.0 %	0.000113
SHIRPA	startle response	males	0.0 %	1.00
SHIRPA	startle response	both	12.0 %	0.000625
SHIRPA	tail curvature	females	0.0 %	1.00
SHIRPA	tail curvature	males	0.0 %	1.0
SHIRPA	tail curvature	both	0.0 %	1.0
SHIRPA	tail elevation	females	1.0 %	1.00
SHIRPA	tail elevation	males	11.0 %	0.142
SHIRPA	tail elevation	both	5.0 %	0.202
SHIRPA	tail length	females	0.0 %	1.0
SHIRPA	tail length	males	0.0 %	1.0
SHIRPA	tail length	both	0.0 %	1.00
SHIRPA	tail morphology	females	0.0 %	1.00
SHIRPA	tail morphology	males	0.0 %	1.0
SHIRPA	tail morphology	both	0.0 %	1.00
SHIRPA	tail presence	females	0.0 %	1.0
SHIRPA	tail presence	males	0.0 %	1.0
SHIRPA	tail presence	both	0.0 %	1.0
SHIRPA	tail shape	females	0.0 %	1.0
SHIRPA	tail shape	males	0.0 %	1.0
SHIRPA	tail shape	both	0.0 %	1.00
SHIRPA	tail thickness	females	0.0 %	1.0
SHIRPA	tail thickness	males	0.0 %	1.0
SHIRPA	tail thickness	both	0.0 %	1.0
SHIRPA	teeth presence	females	0.0 %	1.0
SHIRPA	teeth presence	males	0.0 %	1.00
SHIRPA	teeth presence	both	0.0 %	1.00
SHIRPA	transfer arousal	females	1.0 %	1.0
SHIRPA	transfer arousal	males	12.0 %	0.0653
SHIRPA	transfer arousal	both	6.0 %	0.109
SHIRPA	tremor	females	0.0 %	1.0
SHIRPA	tremor	males	0.0 %	1.0
SHIRPA	tremor	both	0.0 %	1.00
SHIRPA	trunk curl	females	0.0 %	1.00
SHIRPA	trunk curl	males	0.0 %	1.0
SHIRPA	trunk curl	both	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	females	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	males	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	both	0.0 %	1.00
SHIRPA	upper lip morphology	females	0.0 %	1.0
SHIRPA	upper lip morphology	males	0.0 %	1.0
SHIRPA	upper lip morphology	both	0.0 %	1.0
SHIRPA	upper teeth appearance	females	0.0 %	1.0
SHIRPA	upper teeth appearance	males	0.0 %	1.0
SHIRPA	upper teeth appearance	both	0.0 %	1.00
SHIRPA	vibrissae appearance	females	2.0 %	1.0
SHIRPA	vibrissae appearance	males	1.0 %	1.0
SHIRPA	vibrissae appearance	both	1.0 %	1.0
SHIRPA	vibrissae presence	females	2.0 %	1.00
SHIRPA	vibrissae presence	males	1.0 %	1.0
SHIRPA	vibrissae presence	both	2.0 %	1.0
SHIRPA	vocalization	females	2.0 %	1.00
SHIRPA	vocalization	males	11.0 %	0.146
SHIRPA	vocalization	both	4.0 %	0.268

GENOTYPE CORRELATION PLOT

Correlate Myo1d^em1(IMPC)J -/- with genotype: