MPD: JaxKOMP-EAP genotype: Golga5<sup>tm1b(KOMP)Wtsi</sup> -/-

JaxKOMP-EAP effect sizes: Golga5^{tm1b(KOMP)Wtsi} -/- Gene Golga5

MULTIPLE (NUMERIC) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

Procedure	JaxKOMP-EAP Trait	Trait Effect	Trait Effect SE	Trait Effect RankZ	Adjusted p-value	Unadjusted p-value
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 6 kHz pip	1.4126	1.6928	0.16351	0.803	0.419
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 12 kHz pip	0.56367	3.6231	0.13288	0.962	0.879
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 24 kHz pip	-0.30451	4.5347	-0.17470	0.983	0.948
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 30 kHz pip	-4.9457	5.1851	-0.78617	0.698	0.358
body composition	body length	-0.13210	0.051457	-1.1750	0.107	0.0141
body composition	body weight (at time of DXA)	-2.5762	0.50896	-1.4661	0.000269	0.00000919
body composition	bone area, whole body scan, head excluded	-0.77237	0.18479	-2.1779	0.00496	0.000154
body composition	bone mineral content of whole body scan, head excluded	-0.050381	0.012564	-2.0182	0.00947	0.000258
body composition	bone mineral content to body weight ratio	-0.0019997	0.00053400	-1.9590	0.0120	0.000569
body composition	bone mineral density of whole body scan, head excluded	-0.0017271	0.00053767	-1.5738	0.0426	0.00260
body composition	fat tissue mass of whole body scan, head excluded	0.50304	0.37091	0.76837	0.419	0.183
body composition	fat tissue mass to body weight ratio	0.017295	0.013180	0.80559	0.424	0.197
body composition	lean tissue mass of whole body scan, head excluded	0.086308	0.31402	0.023212	0.918	0.785
body composition	lean tissue mass to body weight ratio	0.0089680	0.012046	0.43023	0.697	0.461
body composition	percent fat, whole body scan, head excluded	1.2663	1.2941	0.66254	0.579	0.334
body composition	ratio of soft-tissue attenuation coefficients	-0.0014293	0.0014420	-0.68830	0.573	0.328
body composition	tissue area	0.016114	0.14861	0.25137	0.973	0.914
body composition	total tissue mass, whole body scan, head excluded	0.67335	0.18912	1.1464	0.0145	0.000973
clinical blood chemistry	alanine transaminase (plasma ALT)	19.122	14.720	1.1263	0.585	0.207
clinical blood chemistry	albumin (plasma Alb)	0.10883	0.58977	0.21262	0.949	0.855
clinical blood chemistry	alkaline phosphatase (plasma ALP)	4.6804	5.8881	0.33414	0.674	0.436
clinical blood chemistry	aspartate transaminase (plasma AST)	3.0092	28.773	0.15946	0.980	0.918
clinical blood chemistry	aspartate transaminase to alanine transaminase ratio (plasma AST:ALT)	-0.40559	0.26886	-1.2035	0.524	0.146
clinical blood chemistry	blood urea nitrogen (BUN)	-0.37217	1.9331	-0.18084	0.934	0.849
clinical blood chemistry	calcium (plasma Ca)	0.029392	0.083494	0.53241	0.857	0.728
clinical blood chemistry	creatinine (plasma)	0.0018966	0.024799	0.15279	0.971	0.940
clinical blood chemistry	glucose (plasma GLU, no fast)	-11.328	14.279	-0.15270	0.640	0.436
clinical blood chemistry	HDL cholesterol (plasma HDL)	3.4936	6.2394	0.50773	0.815	0.581
clinical blood chemistry	HDL cholesterol to total cholesterol ratio	-0.021126	0.017895	-1.2851	0.590	0.251
clinical blood chemistry	phosphorus (plasma phosphate)	0.060685	0.33916	0.054891	0.942	0.860
clinical blood chemistry	total bilirubin (plasma TBIL)	0.024271	0.013969	1.3582	0.372	0.0970
clinical blood chemistry	total cholesterol (plasma CHOL, no fast)	5.8616	7.5809	0.75859	0.740	0.448
clinical blood chemistry	total protein (plasma TP)	0.51383	1.0994	0.30590	0.815	0.645
clinical blood chemistry	triglyceride (plasma TG, no fast)	17.078	13.820	1.0708	0.521	0.231
EKG	duration of PQ interval	0.59094	1.0986	0.76591	0.924	0.594
EKG	duration of PR interval	1.1261	1.1460	1.2431	0.861	0.332
EKG	duration of QRS interval	0.95605	0.46166	2.1843	0.885	0.0454
EKG	duration of QT interval	3.0130	1.1177	2.4454	0.311	0.0105
EKG	duration of QTC interval, calculated by dividing QT interval by square root of preceding RR interval	2.6952	1.0481	2.3398	0.538	0.0143
EKG	duration of RR interval	0.79158	1.1428	0.67196	0.818	0.493
EKG	duration of ST interval	2.0179	1.0170	2.0518	0.513	0.0547
EKG	heart rate coefficient of variation (signal intensity)	-0.57175	0.71065	-0.37104	0.871	0.426
EKG	heart rate variability, mean of differences between sequential beats; beats per min	-4.5844	4.9445	-0.46115	0.853	0.360
EKG	heart rate, beats per min	-5.7075	9.6008	-0.62162	0.822	0.556
EKG	mean R amplitude, mean amplitude of signal measured from isoelectric line to peak of QRS	-0.071432	0.088926	-0.71232	0.759	0.427
EKG	mean SR amplitude, mean amplitude of signal measured from signal minimum line to peak of QRS	-0.11168	0.11425	-0.72537	0.674	0.334
EKG	number of signals	-8.5694	3.3571	-1.4703	0.335	0.0148
EKG	proportion of number pairs of successive beat-to-beat intervals that exceed 50 ms	-0.34493	3.7363	0.0061038	0.990	0.927
EKG	QT dispersion, measured as inter-lead variability of QT intervals	-4.9511	3.3359	-1.4025	0.858	0.146
EKG	QTc dispersion, calculated as rate-corrected QT dispersion	-5.5417	3.5655	-1.4412	0.855	0.129
EKG	root mean square of successive differences of neighboring RR intervals	0.97960	1.4834	0.65439	0.899	0.513
glucose tolerance test	amount glucose injected	0.64820	1.8138	0.56249	0.915	0.723
glucose tolerance test	plasma glucose, 0min	8.2951	4.6735	0.62448	0.231	0.0833
glucose tolerance test	plasma glucose, 15min	37.031	21.741	1.1274	0.365	0.0961
glucose tolerance test	plasma glucose, 30min	56.455	17.051	1.6681	0.0423	0.00195
glucose tolerance test	plasma glucose, 60min	53.391	13.591	1.9567	0.0202	0.000321
glucose tolerance test	plasma glucose, 120min	37.910	8.6708	2.0265	0.00750	0.0000822
grip strength	body weight (at time of grip strength test)	-2.7404	0.38727	-1.8546	0.00000514	7.22e-8
grip strength	forelimb and hindlimb grip strength (mean of trials), average	-20.570	11.198	-1.1440	0.219	0.0765
grip strength	forelimb and hindlimb grip strength (mean of trials), average normalized to bw	-0.90759	0.34591	-1.0820	0.0699	0.0135
grip strength	forelimb and hindlimb grip strength by trial, trial1	-9.7494	17.090	-0.43285	0.805	0.573
grip strength	forelimb and hindlimb grip strength by trial, trial2	-17.374	15.503	-0.85243	0.526	0.272
grip strength	forelimb and hindlimb grip strength by trial, trial3	-40.712	11.331	-2.1389	0.0228	0.00115
grip strength	forelimb grip strength (mean of trials), average	-7.5832	7.4651	-0.69746	0.583	0.318
grip strength	forelimb grip strength (mean of trials), average normalized to bw	-0.44531	0.24136	-0.88849	0.266	0.0749
grip strength	forelimb grip strength by trial, trial1	-10.642	9.5414	-0.92575	0.631	0.274
grip strength	forelimb grip strength by trial, trial2	-6.9659	10.844	-0.54080	0.806	0.526
grip strength	forelimb grip strength by trial, trial3	-19.474	7.7892	-1.6695	0.158	0.0181
heart weight	heart weight, normalized to body weight	0.13997	0.18701	0.061522	0.660	0.458
heart weight	heart weight, weight	0.44886	5.3942	-0.31384	0.963	0.934
hematology	basophil differential (percent of total WBC)	-0.34690	0.12389	-2.4799	0.216	0.0107
hematology	calculated hemoglobin (cHGB)	-0.019884	0.45665	-0.35313	0.986	0.966
hematology	eosinophil differential (percent of total WBC)	0.015009	0.57715	0.11444	0.990	0.979
hematology	hematocrit (HCT)	0.58227	1.5780	0.27969	0.862	0.716
hematology	hemoglobin concentration distribution width (HDW)	-0.038257	0.032906	-1.0493	0.569	0.258
hematology	large unstained cells (percent of total WBC)	-0.066229	0.10104	-0.44603	0.803	0.519
hematology	lymphocyte differential (percent of total WBC)	1.9093	1.9380	0.68569	0.588	0.336
hematology	mean corpuscular hemoglobin (CHr)	-0.060891	0.15180	-0.48187	0.848	0.693
hematology	mean platelet volume (MPV)	0.15947	0.14287	0.79634	0.505	0.277
hematology	mean RBC corpuscular hemoglobin (MCH)	0.86050	1.0852	2.0365	0.764	0.437
hematology	mean RBC corpuscular hemoglobin concentration (MCHC)	-0.72458	2.1175	-1.0784	0.908	0.736
hematology	mean RBC corpuscular volume (MCV)	0.54631	0.55626	0.93237	0.569	0.337
hematology	measured hemoglobin (mHGB)	-0.66907	1.0344	-1.3857	0.750	0.525
hematology	monocyte differential (percent of total WBC)	-0.50725	0.28354	-1.1249	0.412	0.0888
hematology	neutrophil differential (percent of total WBC)	-1.6251	1.6051	-0.72069	0.564	0.323
hematology	platelet count (PLT; units per volume x 10³)	39.718	105.48	0.58368	0.892	0.710
hematology	RBC corpuscular distribution width (RDW)	-0.13664	0.26637	-0.49429	0.796	0.613
hematology	RBC corpuscular hemoglobin concentration mean (CHCM)	-0.60942	0.26261	-1.5119	0.146	0.0305
hematology	red blood cell count (RBC; per volume x 10⁶)	0.042296	0.34552	-0.16771	0.954	0.904
hematology	reticulocyte count (Retic; units per volume x 10⁹)	-7.5646	22.218	-0.24343	0.921	0.737
hematology	reticulocyte differential (percent of total RBC)	-0.19219	0.24008	-0.63143	0.752	0.433
hematology	white blood cell count (WBC; units per volume x 10³)	0.47148	0.65089	0.50443	0.662	0.477
holeboard	number of hole pokes by individual hole number, 20 min test, 1	1.0174	1.2267	0.97418	0.795	0.417
holeboard	number of hole pokes by individual hole number, 20 min test, 2	-0.91644	0.81790	-1.3189	0.775	0.276
holeboard	number of hole pokes by individual hole number, 20 min test, 3	-1.0316	1.0113	-1.6335	0.795	0.321
holeboard	number of hole pokes by individual hole number, 20 min test, 4	-1.2758	1.1042	-1.1961	0.715	0.262
holeboard	number of hole pokes by individual hole number, 20 min test, 5	-0.044965	0.63593	0.039678	0.985	0.944
holeboard	number of hole pokes by individual hole number, 20 min test, 6	-0.087952	0.28256	-0.22108	0.968	0.759
holeboard	number of hole pokes by individual hole number, 20 min test, 7	0.30765	0.40087	0.78423	0.905	0.452
holeboard	number of hole pokes by individual hole number, 20 min test, 8	0.0012048	0.45899	0.14142	1.00	0.998
holeboard	number of hole pokes by individual hole number, 20 min test, 9	0.57272	0.43614	1.0646	0.671	0.204
holeboard	number of hole pokes by individual hole number, 20 min test, 10	0.083459	0.35513	0.28985	0.961	0.817
holeboard	number of hole pokes by individual hole number, 20 min test, 11	0.82990	0.50063	1.6938	0.698	0.113
holeboard	number of hole pokes by individual hole number, 20 min test, 12	-0.26396	0.63746	-0.37281	0.936	0.683
holeboard	number of hole pokes by individual hole number, 20 min test, 13	-0.075904	0.80622	0.0016868	0.988	0.926
holeboard	number of hole pokes by individual hole number, 20 min test, 14	0.34128	1.0734	0.63169	0.929	0.754
holeboard	number of hole pokes by individual hole number, 20 min test, 15	0.29524	0.68969	0.52595	0.903	0.673
holeboard	number of hole pokes by individual hole number, 20 min test, 16	0.11646	1.0002	0.12855	0.967	0.908
holeboard	total number of hole pokes, 20 min test	2.0342	4.9414	0.37281	0.847	0.685
light / dark	fecal boli count, 20 min test	4.2942	1.8524	2.9444	0.360	0.0317
light / dark	latency to enter dark zone, 20 min test	23.786	38.334	0.35045	0.853	0.542
light / dark	number of transitions between light and dark zones, 20 min test	12.473	8.9913	1.2235	0.503	0.181
light / dark	percentage of total time in dark zone, 20 min test	1.2453	4.7108	0.36198	0.931	0.794
light / dark	percentage of total time in light zone, 20 min test	-1.2453	4.7108	-0.36776	0.932	0.794
light / dark	time mobile in dark zone, 20 min test	13.871	23.179	0.71493	0.802	0.557
light / dark	time mobile in light zone, 20 min test	3.7328	18.263	-0.0054081	0.927	0.840
light / dark	time spent in dark zone, 20 min test	5.0984	53.993	0.27940	0.976	0.926
light / dark	time spent in light zone, 20 min test	-5.0984	53.993	-0.27940	0.976	0.926
open field	average speed in center of arena, 20 min test	-0.13686	0.42808	-0.35291	0.914	0.751
open field	average speed in periphery of arena, 20 min test	-0.38613	0.19813	-1.8654	0.180	0.0583
open field	distance traveled habituation ratio, 20 min test	10.324	7.3217	0.84622	0.484	0.166
open field	distance traveled in center of arena, 20 min test	-159.65	88.371	-1.3609	0.258	0.0782
open field	distance traveled in periphery of arena, 20 min test	-300.40	207.47	-1.6625	0.364	0.155
open field	distance traveled slope, 20 min test	7.9631	6.7585	0.70989	0.576	0.245
open field	distance traveled, 20 min test, 1st 5min	-95.000	67.601	-1.0669	0.384	0.167
open field	distance traveled, 20 min test, 2nd 5min	5.6602	57.051	-0.43417	0.961	0.921
open field	distance traveled, 20 min test, 3rd 5min	-159.56	70.066	-2.0047	0.129	0.0282
open field	distance traveled, 20 min test, 4th 5min	-28.770	51.457	-0.78444	0.775	0.579
open field	number of clockwise revolution episodes, 20 min test	-2.3561	2.0348	-1.7803	0.615	0.254
open field	number of counter-clockwise revolution episodes, 20 min test	-1.5695	0.88766	-1.2715	0.321	0.0845
open field	number of fecal boli, 20 min test	2.5146	1.3541	2.0294	0.315	0.0707
open field	number of rears in 5 min bins, 20 min test, 1st 5min	-3.8167	2.3793	-1.2563	0.347	0.116
open field	number of rears in 5 min bins, 20 min test, 2nd 5min	0.38750	2.1662	-0.25030	0.943	0.859
open field	number of rears in 5 min bins, 20 min test, 3rd 5min	-2.5334	2.3048	-0.88926	0.554	0.278
open field	number of rears in 5 min bins, 20 min test, 4th 5min	-3.2792	2.5211	-1.0622	0.469	0.201
open field	percentage of total time in center of arena, 20 min test	-3.5564	2.2194	-1.0983	0.407	0.117
open field	percentage of total time in center of arena, slope, 20 min test	-2.4139	1.0993	-1.1333	0.401	0.0338
open field	percentage of total time in center, habituation ratio, 20 min test	-2.4352	1.1578	-1.0885	0.418	0.0416
open field	percentage of total time in corners of arena, 20 min test	4.1014	3.0493	1.0458	0.493	0.186
open field	percentage of total time in corners, habituation ratio, 20 min test	0.54201	1.6553	-0.034243	0.949	0.745
open field	percentage of total time in corners, slope, 20 min test	0.57269	1.6252	-0.014098	0.940	0.726
open field	permanence time in center of arena, 20 min test	-42.688	26.631	-1.0983	0.408	0.117
open field	permanence time in corners of arena, 20 min test	49.205	36.593	1.0458	0.493	0.186
open field	permanence time in periphery of arena, 20 min test	42.690	26.641	1.0958	0.408	0.117
open field	total distance traveled, 20 min test	-502.36	277.34	-1.8006	0.220	0.0776
open field	total number of rears, 20 min test	-9.1458	7.8448	-0.99164	0.497	0.250
open field	whole arena average speed, 20 min test	-0.41812	0.23125	-1.8006	0.220	0.0781
open field	whole arena resting time, 20 min test	42.897	27.877	1.7549	0.296	0.132
open field	whole arena time spent mobile, 20 min test	-42.870	27.861	-2.0047	0.301	0.132
open field	whole arena time spent vertical, 20 min test	-9.4392	8.8492	-0.84622	0.605	0.292
SHIRPA	locomotor activity (number of squares in the arena the mouse moves into with all four paws in first 30 s of test)	-0.97500	1.8727	-0.21608	0.824	0.606
sleep	differential wake percentages during light and dark phase	0.72189	0.41341	1.3699	0.500	0.0941
sleep	mean breath rate during-sleep	-0.041398	0.073504	-0.23655	0.807	0.579
sleep	mean of sleep bout lengths	25.294	32.014	1.0701	0.734	0.438
sleep	mean of sleep bout lengths with lights off	-0.83584	23.642	0.25756	0.984	0.972
sleep	mean of sleep bout lengths with lights on	44.235	42.075	1.1653	0.666	0.304
sleep	mean percentage of time sleeping over 24 h periods	0.40671	1.1494	0.0	0.911	0.727
sleep	mean percentage of time sleeping with lights on	1.0964	1.5278	0.68090	0.862	0.480
sleep	mean percentage of time spent sleeping with lights off	-0.23612	1.3782	-0.41957	0.968	0.865
sleep	peak wake with respect to dark onset median	-0.51233	0.57838	-0.69380	0.860	0.385
sleep	percentage of time awake one hour before and after light onset	-1.2711	6.0153	0.23655	0.947	0.835
startle / PPI	average baseline movement during background noise	-1.9415	1.3492	-1.2876	0.709	0.158
startle / PPI	average of each corrected maximum percent pre-pulse inhibition value	-0.067110	0.062475	-0.71597	0.643	0.289
startle / PPI	average of each corrected percent pre-pulse inhibition value	-0.060841	0.060222	-0.69891	0.664	0.318
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-6.9965	6.1581	-0.71778	0.877	0.262
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-5.8572	6.6021	-0.60275	0.716	0.380
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-5.6850	6.1647	-0.64186	0.665	0.362
startle / PPI	average startle response to full pulse (120 dB)	55.246	30.770	1.1825	0.245	0.0800
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	70.401	31.282	1.2973	0.126	0.0298
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	60.211	30.742	1.2624	0.193	0.0570
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	58.126	28.015	1.3339	0.170	0.0443
startle / PPI	average startle response to pre-pulse, 74dB sound pressure level	0.63333	1.1231	0.49996	0.913	0.576
startle / PPI	average startle response to pre-pulse, 78dB sound pressure level	-0.070139	1.0736	-0.014712	0.991	0.948
startle / PPI	average startle response to pre-pulse, 82dB sound pressure level	0.0027778	1.3968	-0.18103	0.999	0.998
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-0.059797	0.066531	-0.53197	0.879	0.374
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-0.055167	0.071799	-0.53586	0.734	0.447
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-0.066807	0.070084	-0.68864	0.610	0.346
startle / PPI	corrected average startle response to full pulse (120 dB) minus average baseline movement during background noise	56.776	30.688	1.1996	0.222	0.0715
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 74dB sound pressure level	69.526	31.226	1.2876	0.130	0.0315
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 78dB sound pressure level	60.378	30.875	1.2562	0.193	0.0574
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 82dB sound pressure level	58.037	28.176	1.3512	0.170	0.0458
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	0.017478	0.10116	0.19529	0.975	0.864
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-0.071872	0.074394	-0.62770	0.664	0.340
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-0.065958	0.074094	-0.66747	0.638	0.379
startle / PPI	corrected maximum startle response to full pulse (120 dB) minus maximum baseline movement during background noise	219.97	106.51	1.2319	0.171	0.0453
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 74dB sound pressure level	275.08	113.25	1.3689	0.0923	0.0196
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 78dB sound pressure level	231.73	107.05	1.2973	0.141	0.0363
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 82dB sound pressure level	218.47	102.22	1.3512	0.151	0.0386
startle / PPI	maximum baseline movement during background noise	-4.4718	3.1687	-1.1939	0.668	0.166
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	0.76944	9.5234	0.12856	1.00	0.936
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-7.3499	7.0374	-0.70875	0.657	0.302
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-6.2391	6.8395	-0.69441	0.655	0.367
startle / PPI	maximum startle response to full pulse (120 dB)	216.41	106.65	1.2289	0.180	0.0490
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	275.98	113.19	1.3760	0.0917	0.0192
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	230.68	106.78	1.2908	0.143	0.0366
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	220.71	101.52	1.3724	0.144	0.0355
startle / PPI	maximum startle response to pre-pulse, 74dB sound pressure level	0.035676	2.2338	0.13987	0.997	0.987
startle / PPI	maximum startle response to pre-pulse, 78dB sound pressure level	2.2518	3.5998	0.63671	0.877	0.535
startle / PPI	maximum startle response to pre-pulse, 82dB sound pressure level	2.3715	3.7547	0.27890	0.831	0.531

MULTIPLE (CATEGORICAL) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

Procedure	JaxKOMP-EAP Trait	Trait Effect	P-value
eye morphology	anterior chamber depth	6.0 %	0.0613
eye morphology	bulging eye	6.0 %	0.0409
eye morphology	cornea	6.0 %	0.0173
eye morphology	cornea opacity	6.0 %	0.0690
eye morphology	cornea vascularization	6.0 %	0.0695
eye morphology	corneal deposits	6.0 %	0.105
eye morphology	corneal mineralization	6.0 %	0.0612
eye morphology	corneal scleralization	6.0 %	0.0897
eye morphology	corneal ulcer	6.0 %	0.0738
eye morphology	eye closure	6.0 %	0.0408
eye morphology	eye hemorrhage or blood presence	6.0 %	0.0885
eye morphology	eyelid morphology	6.0 %	0.0494
eye morphology	eyes (present, absent)	6.0 %	0.0493
eye morphology	fusion between cornea and lens	6.0 %	0.179
eye morphology	iris pigmentation	6.0 %	0.142
eye morphology	iris transillumination	6.0 %	0.116
eye morphology	irispupil	6.0 %	0.171
eye morphology	lacrimation	6.0 %	0.248
eye morphology	lens	6.0 %	0.134
eye morphology	lens opacity	6.0 %	0.357
eye morphology	narrow eye opening	6.0 %	0.0556
eye morphology	optic disc	5.0 %	0.241
eye morphology	persistence of hyaloid vascular system	6.0 %	0.0961
eye morphology	pupil dilation	6.0 %	0.162
eye morphology	pupil light response	6.0 %	0.236
eye morphology	pupil position	6.0 %	0.186
eye morphology	pupil shape	6.0 %	0.185
eye morphology	retina	6.0 %	0.319
eye morphology	retinal blood vessels	5.0 %	0.196
eye morphology	retinal blood vessels pattern	5.0 %	0.279
eye morphology	retinal blood vessels structure	5.0 %	0.215
eye morphology	retinal pigmentation	6.0 %	0.238
eye morphology	retinal structure	5.0 %	0.223
eye morphology	synechia	5.0 %	0.200
eye morphology	vitreous	5.0 %	0.189
SHIRPA	activity body position	1.0 %	1.00
SHIRPA	aggression	1.0 %	1.0
SHIRPA	body length	0.0 %	1.00
SHIRPA	body position	0.0 %	1.0
SHIRPA	body thickness	0.0 %	1.0
SHIRPA	coat color abdomen	4.0 %	1.0
SHIRPA	coat color back	0.0 %	1.00
SHIRPA	coat color head	0.0 %	1.0
SHIRPA	coat color pattern abdomen	1.0 %	1.0
SHIRPA	coat color pattern back	0.0 %	1.0
SHIRPA	coat color pattern head	0.0 %	1.00
SHIRPA	coat hair abdomen texture appearance	2.0 %	1.0
SHIRPA	coat hair back texture appearance	0.0 %	1.0
SHIRPA	coat hair distribution abdomen	1.0 %	1.00
SHIRPA	coat hair distribution back	0.0 %	1.0
SHIRPA	coat hair distribution head	1.0 %	1.0
SHIRPA	coat hair head texture appearance	0.0 %	1.0
SHIRPA	contact righting	5.0 %	1.00
SHIRPA	ear morphology	0.0 %	1.0
SHIRPA	fat distribution	0.0 %	1.00
SHIRPA	forelimb digit number	0.0 %	1.00
SHIRPA	forelimb digit position	0.0 %	1.0
SHIRPA	forelimb digit shape	0.0 %	1.0
SHIRPA	forelimb digit size	0.0 %	1.0
SHIRPA	forelimb footpads	0.0 %	1.0
SHIRPA	forelimb nail length	0.0 %	1.0
SHIRPA	forelimb nail number	0.0 %	1.0
SHIRPA	forelimb nail position	0.0 %	1.0
SHIRPA	forelimb nail shape	0.0 %	1.0
SHIRPA	forelimbs position	0.0 %	1.0
SHIRPA	forelimbs shape	0.0 %	1.0
SHIRPA	forelimbs size	0.0 %	1.0
SHIRPA	forepaw position	0.0 %	1.0
SHIRPA	forepaw shape	0.0 %	1.0
SHIRPA	forepaw size	0.0 %	1.0
SHIRPA	gait (fluidity)	0.0 %	1.00
SHIRPA	genitalia morphology	0.0 %	1.00
SHIRPA	genitalia presence	0.0 %	1.0
SHIRPA	genitalia size	0.0 %	1.0
SHIRPA	head bobbing	0.0 %	1.0
SHIRPA	head morphology	0.0 %	1.0
SHIRPA	head size	0.0 %	1.00
SHIRPA	hindlimb digit number	0.0 %	1.00
SHIRPA	hindlimb digit position	0.0 %	1.0
SHIRPA	hindlimb digit shape	0.0 %	1.0
SHIRPA	hindlimb digit size	0.0 %	1.00
SHIRPA	hindlimb nail length	0.0 %	1.00
SHIRPA	hindlimb nail number	0.0 %	1.00
SHIRPA	hindlimb nail position	0.0 %	1.0
SHIRPA	hindlimb nail shape	0.0 %	1.0
SHIRPA	hindlimbs footpads	0.0 %	1.0
SHIRPA	hindlimbs position	0.0 %	1.0
SHIRPA	hindlimbs shape	0.0 %	1.0
SHIRPA	hindlimbs size	0.0 %	1.0
SHIRPA	hindpaw position	0.0 %	1.0
SHIRPA	hindpaw shape	0.0 %	1.0
SHIRPA	hindpaw size	0.0 %	1.0
SHIRPA	limb grasp	30.0 %	0.000648
SHIRPA	lower lip morphology	0.0 %	1.0
SHIRPA	lower teeth appearance	0.0 %	1.00
SHIRPA	mouth morphology	0.0 %	1.00
SHIRPA	salivation	0.0 %	1.0
SHIRPA	skin color back paws	0.0 %	1.0
SHIRPA	skin color ear	0.0 %	1.0
SHIRPA	skin color front paws	0.0 %	1.0
SHIRPA	skin color snout	0.0 %	1.0
SHIRPA	skin color tail	0.0 %	1.0
SHIRPA	skin color whole body	0.0 %	1.0
SHIRPA	skin texture back paw	0.0 %	1.0
SHIRPA	skin texture ear	0.0 %	1.0
SHIRPA	skin texture front paws	0.0 %	1.0
SHIRPA	skin texture snout	0.0 %	1.0
SHIRPA	skin texture tail	0.0 %	1.0
SHIRPA	skin texture whole body	0.0 %	1.00
SHIRPA	snout size	0.0 %	1.0
SHIRPA	startle response	0.0 %	1.00
SHIRPA	tail curvature	0.0 %	1.0
SHIRPA	tail elevation	1.0 %	1.0
SHIRPA	tail length	0.0 %	1.00
SHIRPA	tail morphology	0.0 %	1.00
SHIRPA	tail presence	0.0 %	1.0
SHIRPA	tail shape	0.0 %	1.00
SHIRPA	tail thickness	0.0 %	1.0
SHIRPA	teeth presence	0.0 %	1.00
SHIRPA	transfer arousal	1.0 %	1.0
SHIRPA	tremor	0.0 %	1.00
SHIRPA	trunk curl	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	0.0 %	1.00
SHIRPA	upper lip morphology	0.0 %	1.0
SHIRPA	upper teeth appearance	0.0 %	1.00
SHIRPA	vibrissae appearance	1.0 %	1.0
SHIRPA	vibrissae presence	2.0 %	1.0
SHIRPA	vocalization	2.0 %	1.00

GENOTYPE CORRELATION PLOT

Correlate Golga5^{tm1b(KOMP)Wtsi} -/- with genotype: