MPD: JaxKOMP-EAP genotype: Kbtbd7<sup>tm1.1(KOMP)Vlcg</sup> -/-

JaxKOMP-EAP effect sizes: Kbtbd7^{tm1.1(KOMP)Vlcg} -/- Gene Kbtbd7

MULTIPLE (NUMERIC) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

Procedure	JaxKOMP-EAP Trait	Trait Effect	Trait Effect SE	Trait Effect RankZ	Adjusted p-value	Unadjusted p-value
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 6 kHz pip	-1.5243	2.8310	-0.72979	0.872	0.601
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 12 kHz pip	1.8354	3.6366	0.43332	0.886	0.623
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 18 kHz pip	8.1812	5.2813	1.2091	0.505	0.150
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 24 kHz pip	-11.741	5.3591	-1.7523	0.311	0.0509
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 30 kHz pip	-9.1953	3.9441	-1.2589	0.299	0.0398
body composition	body length	0.29067	0.30193	2.3112	0.634	0.339
body composition	body weight (at time of DXA)	-4.5436	0.62784	-2.4014	3.51e-8	2.10e-10
body composition	bone area, whole body scan, head excluded	-0.79320	0.16769	-2.2577	0.000736	0.00000922
body composition	bone mineral content of whole body scan, head excluded	-0.042524	0.013115	-1.7998	0.0289	0.00172
body composition	bone mineral content to body weight ratio	-0.0019322	0.00053384	-1.8814	0.0115	0.000510
body composition	bone mineral density of whole body scan, head excluded	-0.00079440	0.00066365	-0.83580	0.533	0.235
body composition	fat tissue mass of whole body scan, head excluded	1.1415	0.41194	1.5286	0.0674	0.00691
body composition	fat tissue mass to body weight ratio	0.048395	0.014237	1.8354	0.0188	0.00105
body composition	lean tissue mass of whole body scan, head excluded	-0.45532	0.35297	-1.0707	0.503	0.201
body composition	lean tissue mass to body weight ratio	-0.025492	0.012910	-1.3446	0.211	0.0517
body composition	percent fat, whole body scan, head excluded	4.3807	1.3705	1.8067	0.0288	0.00198
body composition	ratio of soft-tissue attenuation coefficients	-0.0048329	0.0015436	-1.7988	0.0323	0.00242
body composition	tissue area	0.26320	0.22512	0.99097	0.545	0.246
body composition	total tissue mass, whole body scan, head excluded	0.72055	0.24294	1.1868	0.0380	0.00395
clinical blood chemistry	alanine transaminase (plasma ALT)	12.503	5.2821	0.87189	0.281	0.0246
clinical blood chemistry	alkaline phosphatase (plasma ALP)	13.864	3.2307	1.5052	0.00549	0.000170
clinical blood chemistry	aspartate transaminase (plasma AST)	71.929	15.471	1.9067	0.00409	0.0000672
clinical blood chemistry	aspartate transaminase to alanine transaminase ratio (plasma AST:ALT)	0.59947	0.41725	1.5546	0.542	0.162
clinical blood chemistry	blood urea nitrogen (BUN)	7.1754	2.0602	2.4356	0.0369	0.00235
clinical blood chemistry	calcium (plasma Ca)	-0.31219	0.13721	-1.7410	0.144	0.0307
clinical blood chemistry	creatinine (plasma)	0.051101	0.022268	1.3133	0.158	0.0327
clinical blood chemistry	glucose (plasma GLU, no fast)	-40.917	10.439	-1.0770	0.00633	0.000498
clinical blood chemistry	HDL cholesterol (plasma HDL)	2.9180	3.9637	0.38402	0.744	0.468
clinical blood chemistry	HDL cholesterol to total cholesterol ratio	-0.010380	0.013107	-0.71297	0.735	0.435
clinical blood chemistry	phosphorus (plasma phosphate)	0.034633	0.68932	0.019239	0.984	0.960
clinical blood chemistry	total bilirubin (plasma TBIL)	0.11859	0.015023	2.8387	0.0000146	8.25e-9
clinical blood chemistry	total cholesterol (plasma CHOL, no fast)	4.2819	5.5306	0.51610	0.738	0.445
clinical blood chemistry	total protein (plasma TP)	-5.9265	2.9877	-2.3385	0.269	0.0568
clinical blood chemistry	triglyceride (plasma TG, no fast)	13.274	18.085	0.90748	0.726	0.471
EKG	duration of PQ interval	1.8682	0.84920	1.9753	0.505	0.0386
EKG	duration of PR interval	2.2621	0.94288	2.0686	0.469	0.0253
EKG	duration of QRS interval	0.17763	0.45693	0.33671	0.967	0.701
EKG	duration of QT interval	-0.91137	1.0288	-0.68719	0.858	0.385
EKG	duration of QTC interval, calculated by dividing QT interval by square root of preceding RR interval	-1.5298	0.90773	-1.5196	0.687	0.105
EKG	duration of RR interval	3.5625	1.8399	1.9753	0.420	0.0652
EKG	duration of ST interval	-0.11208	1.0390	0.10497	0.975	0.915
EKG	heart rate coefficient of variation (signal intensity)	2.5470	1.2447	1.9345	0.709	0.0523
EKG	heart rate variability, mean of differences between sequential beats; beats per min	14.846	8.3291	1.6703	0.789	0.0879
EKG	heart rate, beats per min	-21.571	13.935	-1.5587	0.512	0.135
EKG	mean R amplitude, mean amplitude of signal measured from isoelectric line to peak of QRS	0.19725	0.086140	1.4295	0.281	0.0315
EKG	mean SR amplitude, mean amplitude of signal measured from signal minimum line to peak of QRS	0.23552	0.10750	1.2783	0.274	0.0389
EKG	number of signals	2.3735	6.0513	0.45443	0.936	0.699
EKG	proportion of number pairs of successive beat-to-beat intervals that exceed 50 ms	25.649	7.7020	2.9434	0.538	0.00291
EKG	QT dispersion, measured as inter-lead variability of QT intervals	-1.9053	3.3057	-0.53646	0.964	0.570
EKG	QTc dispersion, calculated as rate-corrected QT dispersion	-3.6087	3.6956	-0.97820	0.895	0.339
EKG	root mean square of successive differences of neighboring RR intervals	-0.83725	1.7191	-0.33245	0.927	0.631
glucose tolerance test	amount glucose injected	0.076350	2.8708	0.40472	0.988	0.979
glucose tolerance test	plasma glucose, 0min	5.5727	5.0823	0.32985	0.493	0.277
glucose tolerance test	plasma glucose, 15min	1.6131	20.287	0.14048	0.975	0.937
glucose tolerance test	plasma glucose, 30min	-8.1737	21.785	-0.11833	0.884	0.709
glucose tolerance test	plasma glucose, 60min	-23.356	18.714	-0.87778	0.541	0.217
glucose tolerance test	plasma glucose, 120min	-26.827	13.678	-1.8256	0.297	0.0543
grip strength	body weight (at time of grip strength test)	-2.7227	0.50067	-1.8465	0.0000965	0.00000291
grip strength	forelimb and hindlimb grip strength (mean of trials), average	-36.479	6.3545	-2.0600	0.000145	0.00000109
grip strength	forelimb and hindlimb grip strength (mean of trials), average normalized to bw	-1.6416	0.39713	-1.9922	0.00460	0.000183
grip strength	forelimb and hindlimb grip strength by trial, trial1	-24.437	9.6323	-1.3528	0.109	0.0153
grip strength	forelimb and hindlimb grip strength by trial, trial2	-36.537	7.6479	-2.0480	0.00318	0.0000240
grip strength	forelimb and hindlimb grip strength by trial, trial3	-36.700	8.3045	-1.9516	0.00410	0.0000737
grip strength	forelimb grip strength (mean of trials), average	-6.3387	6.4303	-0.54080	0.592	0.330
grip strength	forelimb grip strength (mean of trials), average normalized to bw	-0.092847	0.23219	-0.0043568	0.859	0.691
grip strength	forelimb grip strength by trial, trial1	-3.1976	8.3096	-0.10768	0.879	0.702
grip strength	forelimb grip strength by trial, trial2	-8.2977	7.6433	-0.67723	0.606	0.284
grip strength	forelimb grip strength by trial, trial3	-11.322	5.4469	-0.94600	0.238	0.0441
heart weight	heart weight, normalized to body weight	-0.38532	0.15639	-1.8860	0.0909	0.0184
heart weight	heart weight, weight	-10.570	4.5492	-1.7038	0.122	0.0256
hematology	basophil differential (percent of total WBC)	-0.038261	0.041053	-0.57033	0.754	0.359
hematology	calculated hemoglobin (cHGB)	-0.093711	0.15696	-0.57618	0.780	0.555
hematology	eosinophil differential (percent of total WBC)	-0.42275	0.20440	-1.0942	0.332	0.0476
hematology	hematocrit (HCT)	-0.28947	0.48062	-0.64140	0.759	0.552
hematology	hemoglobin concentration distribution width (HDW)	-0.091537	0.021589	-2.0962	0.00907	0.000208
hematology	large unstained cells (percent of total WBC)	0.056323	0.15355	0.39291	0.887	0.716
hematology	lymphocyte differential (percent of total WBC)	5.0692	2.2794	1.6225	0.174	0.0341
hematology	mean corpuscular hemoglobin (CHr)	-0.10430	0.075412	-0.84083	0.400	0.177
hematology	mean platelet volume (MPV)	0.071472	0.096322	0.28865	0.686	0.464
hematology	mean RBC corpuscular hemoglobin (MCH)	0.33846	0.79093	1.2313	0.860	0.672
hematology	mean RBC corpuscular hemoglobin concentration (MCHC)	1.0082	1.7770	1.5868	0.826	0.575
hematology	mean RBC corpuscular volume (MCV)	0.55849	0.32651	0.95369	0.257	0.0982
hematology	measured hemoglobin (mHGB)	0.38733	0.80242	0.80440	0.822	0.633
hematology	monocyte differential (percent of total WBC)	-0.32381	0.13378	-0.82000	0.232	0.0220
hematology	neutrophil differential (percent of total WBC)	-4.3415	2.1722	-1.5783	0.224	0.0551
hematology	platelet count (PLT; units per volume x 10³)	13.354	48.992	0.22045	0.922	0.787
hematology	RBC corpuscular distribution width (RDW)	-0.69535	0.15499	-2.0719	0.00482	0.000105
hematology	RBC corpuscular hemoglobin concentration mean (CHCM)	-0.70447	0.26174	-1.6795	0.0783	0.0119
hematology	red blood cell count (RBC; per volume x 10⁶)	0.044111	0.10473	-0.15246	0.842	0.677
hematology	reticulocyte count (Retic; units per volume x 10⁹)	16.138	16.493	0.75473	0.712	0.336
hematology	reticulocyte differential (percent of total RBC)	0.16120	0.15619	0.84376	0.676	0.311
hematology	white blood cell count (WBC; units per volume x 10³)	2.8300	0.67218	1.8972	0.00442	0.000225
holeboard	number of hole pokes by individual hole number, 20 min test, 1	-0.81548	0.67207	-0.75794	0.705	0.229
holeboard	number of hole pokes by individual hole number, 20 min test, 2	0.54695	0.45587	0.97690	0.751	0.234
holeboard	number of hole pokes by individual hole number, 20 min test, 3	0.12148	0.39616	0.30778	0.948	0.760
holeboard	number of hole pokes by individual hole number, 20 min test, 4	-0.58912	0.54208	-0.53898	0.729	0.281
holeboard	number of hole pokes by individual hole number, 20 min test, 5	0.10211	0.37624	0.28309	0.956	0.787
holeboard	number of hole pokes by individual hole number, 20 min test, 6	0.26103	0.23064	0.73394	0.834	0.261
holeboard	number of hole pokes by individual hole number, 20 min test, 7	0.42187	0.19924	1.0731	0.621	0.0375
holeboard	number of hole pokes by individual hole number, 20 min test, 8	-0.48202	0.46529	-0.69853	0.790	0.303
holeboard	number of hole pokes by individual hole number, 20 min test, 9	0.56766	0.37321	1.0557	0.585	0.132
holeboard	number of hole pokes by individual hole number, 20 min test, 10	0.18452	0.29434	0.53335	0.908	0.533
holeboard	number of hole pokes by individual hole number, 20 min test, 11	0.44676	0.22305	1.0766	0.623	0.0487
holeboard	number of hole pokes by individual hole number, 20 min test, 12	1.2361	0.36858	1.7088	0.0920	0.00124
holeboard	number of hole pokes by individual hole number, 20 min test, 13	0.15582	0.70342	0.24360	0.955	0.825
holeboard	number of hole pokes by individual hole number, 20 min test, 14	1.6971	0.51880	2.2327	0.173	0.00160
holeboard	number of hole pokes by individual hole number, 20 min test, 15	0.98667	0.36731	1.4513	0.300	0.00885
holeboard	number of hole pokes by individual hole number, 20 min test, 16	1.0201	0.82925	0.89877	0.638	0.222
holeboard	total number of hole pokes, 20 min test	5.8756	3.1953	0.87874	0.290	0.0698
light / dark	fecal boli count, 20 min test	1.6230	0.61942	1.6278	0.229	0.0104
light / dark	latency to enter dark zone, 20 min test	67.388	34.519	1.0914	0.431	0.0542
light / dark	number of transitions between light and dark zones, 20 min test	-4.0632	6.6110	-0.31047	0.787	0.540
light / dark	percentage of total time in dark zone, 20 min test	-4.7361	3.9083	-0.73074	0.602	0.229
light / dark	percentage of total time in light zone, 20 min test	4.7361	3.9083	0.72897	0.602	0.229
light / dark	time mobile in dark zone, 20 min test	71.503	13.911	2.3587	0.000123	0.00000173
light / dark	time mobile in light zone, 20 min test	83.292	10.513	2.6264	4.18e-9	8.10e-12
light / dark	time spent in dark zone, 20 min test	-101.27	51.475	-1.2009	0.381	0.0524
light / dark	time spent in light zone, 20 min test	101.27	51.475	1.2009	0.381	0.0524
open field	average speed in center of arena, 20 min test	0.74229	0.36500	1.1461	0.290	0.0452
open field	average speed in periphery of arena, 20 min test	1.6585	0.13834	2.5186	6.35e-17	1.02e-19
open field	distance traveled habituation ratio, 20 min test	-47.844	5.8896	-2.6738	3.71e-9	3.98e-12
open field	distance traveled in center of arena, 20 min test	1216.3	95.294	3.2711	6.58e-18	3.53e-21
open field	distance traveled in periphery of arena, 20 min test	913.33	142.57	2.0148	7.15e-7	9.20e-9
open field	distance traveled slope, 20 min test	-49.116	5.7888	-2.7251	4.74e-10	7.63e-13
open field	distance traveled, 20 min test, 1st 5min	760.98	61.514	2.6738	1.20e-17	1.92e-20
open field	distance traveled, 20 min test, 2nd 5min	540.71	58.465	2.4592	1.08e-11	2.31e-14
open field	distance traveled, 20 min test, 3rd 5min	363.19	51.042	2.1845	6.49e-8	3.83e-10
open field	distance traveled, 20 min test, 4th 5min	329.57	40.417	2.0688	1.29e-9	3.46e-12
open field	number of clockwise revolution episodes, 20 min test	11.357	1.5366	2.6286	6.89e-8	1.11e-10
open field	number of counter-clockwise revolution episodes, 20 min test	8.7383	1.3578	2.4074	0.00000241	7.79e-9
open field	number of fecal boli, 20 min test	2.1705	0.95331	1.7802	0.202	0.0254
open field	number of rears in 5 min bins, 20 min test, 1st 5min	4.9906	2.3221	1.1406	0.179	0.0346
open field	number of rears in 5 min bins, 20 min test, 2nd 5min	-0.16788	2.3914	-0.40048	0.980	0.944
open field	number of rears in 5 min bins, 20 min test, 3rd 5min	-3.5878	2.5007	-1.1333	0.415	0.155
open field	number of rears in 5 min bins, 20 min test, 4th 5min	-4.9310	3.1263	-1.3956	0.361	0.119
open field	percentage of total time in center of arena, 20 min test	22.215	2.7408	3.2711	8.06e-9	4.32e-12
open field	percentage of total time in center of arena, slope, 20 min test	3.8342	1.5073	2.2147	0.304	0.0129
open field	percentage of total time in center, habituation ratio, 20 min test	3.9011	1.5689	2.1562	0.303	0.0150
open field	percentage of total time in corners of arena, 20 min test	-21.155	3.6401	-2.9465	0.000107	1.14e-7
open field	percentage of total time in corners, habituation ratio, 20 min test	0.81425	1.6403	0.093446	0.921	0.621
open field	percentage of total time in corners, slope, 20 min test	0.94948	1.5783	0.15842	0.897	0.549
open field	permanence time in center of arena, 20 min test	266.59	32.888	3.2711	8.04e-9	4.31e-12
open field	permanence time in corners of arena, 20 min test	-253.86	43.680	-2.9465	0.000106	1.14e-7
open field	permanence time in periphery of arena, 20 min test	-266.63	32.891	-3.2711	8.03e-9	4.30e-12
open field	total distance traveled, 20 min test	1992.0	177.26	2.4592	1.76e-15	2.82e-18
open field	total number of rears, 20 min test	-6.1829	8.8577	-0.78080	0.712	0.487
open field	whole arena average speed, 20 min test	1.6596	0.14771	2.4592	1.77e-15	2.85e-18
open field	whole arena resting time, 20 min test	-204.21	17.987	-2.6738	9.33e-16	2.00e-18
open field	whole arena time spent mobile, 20 min test	204.15	17.977	2.6738	9.23e-16	1.98e-18
open field	whole arena time spent vertical, 20 min test	-30.305	7.5215	-2.1296	0.00528	0.000125
SHIRPA	locomotor activity (number of squares in the arena the mouse moves into with all four paws in first 30 s of test)	0.64644	1.3452	0.45184	0.845	0.633
startle / PPI	average baseline movement during background noise	6.8900	2.1146	2.5737	0.224	0.00226
startle / PPI	average of each corrected maximum percent pre-pulse inhibition value	-0.018047	0.066360	-0.25856	0.914	0.787
startle / PPI	average of each corrected percent pre-pulse inhibition value	-0.051675	0.063004	-0.60015	0.745	0.417
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	3.4791	5.0460	0.43278	0.895	0.494
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-2.1665	6.0877	-0.26726	0.905	0.724
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-12.657	16.816	-1.3006	0.733	0.456
startle / PPI	average startle response to full pulse (120 dB)	37.803	45.907	0.93475	0.658	0.415
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	18.633	41.621	0.60275	0.826	0.657
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	56.956	42.172	1.1996	0.394	0.184
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	61.413	63.212	1.3653	0.563	0.337
startle / PPI	average startle response to pre-pulse, 74dB sound pressure level	0.53827	1.9171	0.43894	0.967	0.780
startle / PPI	average startle response to pre-pulse, 78dB sound pressure level	2.0792	2.0048	1.0815	0.814	0.306
startle / PPI	average startle response to pre-pulse, 82dB sound pressure level	6.9147	3.0525	1.9867	0.293	0.0287
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-0.0063273	0.056177	-0.025924	0.991	0.911
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	0.0045005	0.074770	-0.047008	0.991	0.952
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-0.027429	0.082904	-0.40777	0.892	0.742
startle / PPI	corrected average startle response to full pulse (120 dB) minus average baseline movement during background noise	31.739	45.595	0.83525	0.720	0.490
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 74dB sound pressure level	18.412	42.038	0.59270	0.830	0.664
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 78dB sound pressure level	54.901	42.623	1.1797	0.418	0.205
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 82dB sound pressure level	46.252	34.483	1.1939	0.392	0.187
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-0.017591	0.065397	-0.11585	0.966	0.789
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	0.040857	0.078920	0.21186	0.821	0.607
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-0.024328	0.083552	-0.38049	0.905	0.772
startle / PPI	corrected maximum startle response to full pulse (120 dB) minus maximum baseline movement during background noise	177.90	166.55	1.0865	0.536	0.292
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 74dB sound pressure level	106.61	145.04	0.71960	0.679	0.467
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 78dB sound pressure level	177.35	156.45	1.0840	0.481	0.264
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 82dB sound pressure level	183.42	126.95	1.2349	0.356	0.156
startle / PPI	maximum baseline movement during background noise	13.264	4.9611	2.3240	0.318	0.0107
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	0.15545	6.2447	0.055373	1.00	0.980
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	1.2260	6.9624	0.021719	0.946	0.861
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-4.0159	7.4369	-0.49362	0.803	0.592
startle / PPI	maximum startle response to full pulse (120 dB)	188.71	167.95	1.1174	0.509	0.268
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	106.20	143.85	0.72323	0.676	0.465
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	183.92	155.20	1.1096	0.458	0.243
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	194.11	125.60	1.2781	0.316	0.130
startle / PPI	maximum startle response to pre-pulse, 74dB sound pressure level	-0.074348	4.3655	0.091903	0.997	0.986
startle / PPI	maximum startle response to pre-pulse, 78dB sound pressure level	5.4967	4.7425	1.2531	0.751	0.253
startle / PPI	maximum startle response to pre-pulse, 82dB sound pressure level	12.968	6.1349	1.6419	0.332	0.0407

MULTIPLE (CATEGORICAL) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

Procedure	JaxKOMP-EAP Trait	Trait Effect	P-value
eye morphology	anterior chamber depth	1.0 %	1.0
eye morphology	bulging eye	1.0 %	1.00
eye morphology	cornea	3.0 %	1.00
eye morphology	cornea opacity	3.0 %	1.00
eye morphology	cornea vascularization	2.0 %	1.00
eye morphology	corneal deposits	1.0 %	1.00
eye morphology	corneal mineralization	1.0 %	1.0
eye morphology	corneal scleralization	2.0 %	1.00
eye morphology	corneal ulcer	1.0 %	1.0
eye morphology	eye closure	1.0 %	1.00
eye morphology	eye hemorrhage or blood presence	1.0 %	1.00
eye morphology	eyelid morphology	1.0 %	1.00
eye morphology	eyes (present, absent)	0.0 %	1.00
eye morphology	fusion between cornea and lens	3.0 %	1.00
eye morphology	iris pigmentation	2.0 %	1.00
eye morphology	iris transillumination	1.0 %	1.00
eye morphology	irispupil	12.0 %	0.0779
eye morphology	lacrimation	36.0 %	5.05e-8
eye morphology	lens	9.0 %	1.00
eye morphology	lens opacity	16.0 %	0.0413
eye morphology	narrow eye opening	1.0 %	1.00
eye morphology	optic disc	3.0 %	1.00
eye morphology	persistence of hyaloid vascular system	3.0 %	0.719
eye morphology	pupil dilation	2.0 %	1.00
eye morphology	pupil light response	2.0 %	1.00
eye morphology	pupil position	7.0 %	0.267
eye morphology	pupil shape	3.0 %	1.00
eye morphology	retina	13.0 %	1.00
eye morphology	retinal blood vessels	3.0 %	1.00
eye morphology	retinal blood vessels pattern	4.0 %	1.00
eye morphology	retinal blood vessels structure	3.0 %	1.00
eye morphology	retinal pigmentation	13.0 %	1.00
eye morphology	retinal structure	3.0 %	1.00
eye morphology	synechia	3.0 %	1.00
eye morphology	vitreous	3.0 %	1.00
SHIRPA	activity body position	6.0 %	0.182
SHIRPA	aggression	1.0 %	1.00
SHIRPA	body length	0.0 %	1.0
SHIRPA	body position	0.0 %	1.00
SHIRPA	body thickness	0.0 %	1.00
SHIRPA	coat color abdomen	4.0 %	1.00
SHIRPA	coat color back	0.0 %	1.00
SHIRPA	coat color head	0.0 %	1.0
SHIRPA	coat color pattern abdomen	1.0 %	1.00
SHIRPA	coat color pattern back	0.0 %	1.00
SHIRPA	coat color pattern head	0.0 %	1.0
SHIRPA	coat hair abdomen texture appearance	2.0 %	1.0
SHIRPA	coat hair back texture appearance	0.0 %	1.0
SHIRPA	coat hair distribution abdomen	1.0 %	1.0
SHIRPA	coat hair distribution back	0.0 %	1.00
SHIRPA	coat hair distribution head	1.0 %	1.0
SHIRPA	coat hair head texture appearance	0.0 %	1.0
SHIRPA	contact righting	5.0 %	1.00
SHIRPA	ear morphology	0.0 %	1.0
SHIRPA	fat distribution	0.0 %	1.0
SHIRPA	forelimb digit number	0.0 %	1.0
SHIRPA	forelimb digit position	0.0 %	1.0
SHIRPA	forelimb digit shape	0.0 %	1.0
SHIRPA	forelimb digit size	0.0 %	1.0
SHIRPA	forelimb footpads	0.0 %	1.0
SHIRPA	forelimb nail length	0.0 %	1.0
SHIRPA	forelimb nail number	0.0 %	1.0
SHIRPA	forelimb nail position	0.0 %	1.0
SHIRPA	forelimb nail shape	0.0 %	1.0
SHIRPA	forelimbs position	0.0 %	1.0
SHIRPA	forelimbs shape	0.0 %	1.0
SHIRPA	forelimbs size	0.0 %	1.0
SHIRPA	forepaw position	0.0 %	1.0
SHIRPA	forepaw shape	0.0 %	1.0
SHIRPA	forepaw size	0.0 %	1.0
SHIRPA	gait (fluidity)	0.0 %	1.0
SHIRPA	genitalia morphology	0.0 %	1.00
SHIRPA	genitalia presence	0.0 %	1.0
SHIRPA	genitalia size	0.0 %	1.00
SHIRPA	head bobbing	0.0 %	1.0
SHIRPA	head morphology	0.0 %	1.0
SHIRPA	head size	0.0 %	1.0
SHIRPA	hindlimb digit number	0.0 %	1.0
SHIRPA	hindlimb digit position	0.0 %	1.0
SHIRPA	hindlimb digit shape	0.0 %	1.00
SHIRPA	hindlimb digit size	0.0 %	1.00
SHIRPA	hindlimb nail length	0.0 %	1.0
SHIRPA	hindlimb nail number	0.0 %	1.0
SHIRPA	hindlimb nail position	0.0 %	1.0
SHIRPA	hindlimb nail shape	0.0 %	1.0
SHIRPA	hindlimbs footpads	0.0 %	1.0
SHIRPA	hindlimbs position	0.0 %	1.0
SHIRPA	hindlimbs shape	0.0 %	1.0
SHIRPA	hindlimbs size	0.0 %	1.0
SHIRPA	hindpaw position	0.0 %	1.0
SHIRPA	hindpaw shape	0.0 %	1.0
SHIRPA	hindpaw size	0.0 %	1.0
SHIRPA	limb grasp	7.0 %	0.620
SHIRPA	lower lip morphology	0.0 %	1.0
SHIRPA	lower teeth appearance	7.0 %	0.0138
SHIRPA	mouth morphology	0.0 %	1.0
SHIRPA	salivation	0.0 %	1.0
SHIRPA	skin color back paws	0.0 %	1.0
SHIRPA	skin color ear	0.0 %	1.0
SHIRPA	skin color front paws	0.0 %	1.0
SHIRPA	skin color snout	0.0 %	1.0
SHIRPA	skin color tail	0.0 %	1.0
SHIRPA	skin color whole body	0.0 %	1.0
SHIRPA	skin texture back paw	0.0 %	1.0
SHIRPA	skin texture ear	0.0 %	1.0
SHIRPA	skin texture front paws	0.0 %	1.0
SHIRPA	skin texture snout	0.0 %	1.0
SHIRPA	skin texture tail	0.0 %	1.0
SHIRPA	skin texture whole body	0.0 %	1.00
SHIRPA	snout size	0.0 %	1.0
SHIRPA	startle response	0.0 %	1.0
SHIRPA	tail curvature	0.0 %	1.00
SHIRPA	tail elevation	25.0 %	0.0000613
SHIRPA	tail length	0.0 %	1.0
SHIRPA	tail morphology	0.0 %	1.00
SHIRPA	tail presence	0.0 %	1.0
SHIRPA	tail shape	0.0 %	1.0
SHIRPA	tail thickness	0.0 %	1.0
SHIRPA	teeth presence	0.0 %	1.0
SHIRPA	transfer arousal	1.0 %	1.0
SHIRPA	tremor	0.0 %	1.00
SHIRPA	trunk curl	0.0 %	1.00
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	0.0 %	1.0
SHIRPA	upper lip morphology	0.0 %	1.0
SHIRPA	upper teeth appearance	7.0 %	0.0138
SHIRPA	vibrissae appearance	1.0 %	1.0
SHIRPA	vibrissae presence	2.0 %	1.0
SHIRPA	vocalization	2.0 %	1.0

GENOTYPE CORRELATION PLOT

Correlate Kbtbd7^{tm1.1(KOMP)Vlcg} -/- with genotype: