MPD: JaxKOMP-EAP genotype: Gtpbp10<sup>tm1b(KOMP)Mbp</sup> -/-

JaxKOMP-EAP effect sizes: Gtpbp10^{tm1b(KOMP)Mbp} -/- Gene Gtpbp10

MULTIPLE (NUMERIC) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

Procedure	JaxKOMP-EAP Trait	Trait Effect	Trait Effect SE	Trait Effect RankZ	Adjusted p-value	Unadjusted p-value
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 6 kHz pip	-0.042673	1.7792	-0.29072	0.996	0.982
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 12 kHz pip	-0.76389	1.8320	-0.16009	0.909	0.698
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 18 kHz pip	-0.69444	2.1655	-0.34848	0.919	0.764
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 24 kHz pip	1.4578	5.7412	0.11071	0.931	0.812
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 30 kHz pip	-0.36077	6.0210	-0.078588	0.984	0.955
body composition	body length	-0.12426	0.041978	-1.1116	0.0504	0.00447
body composition	body weight (at time of DXA)	0.87283	0.58103	0.78911	0.325	0.138
body composition	bone area, whole body scan, head excluded	-0.24208	0.13244	-0.78499	0.274	0.0728
body composition	bone mineral content of whole body scan, head excluded	-0.020951	0.0099032	-0.96960	0.190	0.0388
body composition	bone mineral content to body weight ratio	-0.0010681	0.00041942	-1.1281	0.0932	0.0136
body composition	bone mineral density of whole body scan, head excluded	-0.00094549	0.00047428	-0.96271	0.234	0.0510
body composition	fat tissue mass of whole body scan, head excluded	0.63399	0.30570	0.93946	0.193	0.0426
body composition	fat tissue mass to body weight ratio	0.021998	0.010566	0.96090	0.166	0.0418
body composition	lean tissue mass of whole body scan, head excluded	-0.48069	0.21610	-1.1153	0.190	0.0301
body composition	lean tissue mass to body weight ratio	-0.022085	0.0082888	-1.1837	0.0896	0.0100
body composition	percent fat, whole body scan, head excluded	2.1822	1.0029	1.0257	0.149	0.0337
body composition	ratio of soft-tissue attenuation coefficients	-0.0023679	0.0011171	-1.0151	0.160	0.0384
body composition	tissue area	0.15199	0.13606	0.67192	0.569	0.269
body composition	total tissue mass, whole body scan, head excluded	0.16210	0.20654	0.15766	0.679	0.436
clinical blood chemistry	alanine transaminase (plasma ALT)	-2.5567	15.934	-0.26595	0.961	0.874
clinical blood chemistry	albumin (plasma Alb)	0.035341	0.44848	0.12293	0.986	0.938
clinical blood chemistry	alkaline phosphatase (plasma ALP)	3.3733	3.4018	0.064517	0.579	0.330
clinical blood chemistry	aspartate transaminase (plasma AST)	1.1727	25.522	0.066685	0.987	0.964
clinical blood chemistry	aspartate transaminase to alanine transaminase ratio (plasma AST:ALT)	0.25946	0.17084	0.82196	0.524	0.140
clinical blood chemistry	blood urea nitrogen (BUN)	-5.2220	1.3172	-1.7707	0.0122	0.000462
clinical blood chemistry	calcium (plasma Ca)	0.034666	0.085053	0.57048	0.827	0.687
clinical blood chemistry	creatinine (plasma)	-0.050751	0.033777	-0.99553	0.367	0.149
clinical blood chemistry	glucose (plasma GLU, no fast)	12.244	16.207	0.76662	0.656	0.456
clinical blood chemistry	HDL cholesterol (plasma HDL)	-4.5209	2.6582	-1.2374	0.346	0.0997
clinical blood chemistry	HDL cholesterol to total cholesterol ratio	-0.0092500	0.012357	-0.65540	0.753	0.460
clinical blood chemistry	phosphorus (plasma phosphate)	0.011888	0.44754	-0.019239	0.994	0.979
clinical blood chemistry	total bilirubin (plasma TBIL)	-0.0042100	0.021225	-0.31901	0.945	0.844
clinical blood chemistry	total cholesterol (plasma CHOL, no fast)	-9.3243	3.9417	-1.5929	0.158	0.0249
clinical blood chemistry	total protein (plasma TP)	-0.87751	0.76577	-0.73862	0.539	0.261
clinical blood chemistry	triglyceride (plasma TG, no fast)	-9.4695	7.3297	-0.30512	0.499	0.207
EKG	duration of PQ interval	0.50500	0.74042	0.68210	0.900	0.501
EKG	duration of PR interval	0.55625	0.84495	0.65189	0.909	0.516
EKG	duration of QRS interval	0.070050	0.35528	0.062505	0.988	0.845
EKG	duration of QT interval	0.73940	0.90234	0.88193	0.858	0.419
EKG	duration of QTC interval, calculated by dividing QT interval by square root of preceding RR interval	1.2625	0.89348	1.3307	0.739	0.168
EKG	duration of RR interval	-0.50299	0.89253	0.0080600	0.840	0.578
EKG	duration of ST interval	0.72772	0.87011	0.94935	0.830	0.410
EKG	heart rate coefficient of variation (signal intensity)	-0.79138	0.71920	-0.53879	0.848	0.280
EKG	heart rate variability, mean of differences between sequential beats; beats per min	-6.0338	5.2811	-0.62472	0.853	0.263
EKG	heart rate, beats per min	4.6651	7.8477	-0.0010083	0.823	0.557
EKG	mean R amplitude, mean amplitude of signal measured from isoelectric line to peak of QRS	0.12875	0.082410	0.85201	0.474	0.129
EKG	mean SR amplitude, mean amplitude of signal measured from signal minimum line to peak of QRS	0.13375	0.099998	0.68912	0.554	0.191
EKG	number of signals	0.83750	3.2622	0.15374	0.961	0.799
EKG	proportion of number pairs of successive beat-to-beat intervals that exceed 50 ms	-3.0048	2.4938	-0.47963	0.814	0.238
EKG	QT dispersion, measured as inter-lead variability of QT intervals	-0.91250	1.5926	-0.23384	0.964	0.571
EKG	QTc dispersion, calculated as rate-corrected QT dispersion	-1.7187	1.6902	-0.44997	0.892	0.318
EKG	root mean square of successive differences of neighboring RR intervals	0.26737	0.98814	0.25044	0.952	0.789
glucose tolerance test	amount glucose injected	-2.3974	2.2277	-0.33987	0.660	0.289
glucose tolerance test	plasma glucose, 0min	-34.194	9.2931	-2.5107	0.00912	0.000705
glucose tolerance test	plasma glucose, 15min	-55.061	30.230	-1.3729	0.326	0.0762
glucose tolerance test	plasma glucose, 30min	8.0766	25.310	0.36778	0.903	0.751
glucose tolerance test	plasma glucose, 60min	-20.629	17.996	-0.75697	0.592	0.259
glucose tolerance test	plasma glucose, 120min	8.0394	9.2491	0.40625	0.671	0.390
grip strength	body weight (at time of grip strength test)	0.013945	0.54549	0.22826	0.988	0.980
grip strength	forelimb and hindlimb grip strength (mean of trials), average	-16.879	7.3840	-0.90368	0.113	0.0300
grip strength	forelimb and hindlimb grip strength (mean of trials), average normalized to bw	-0.76291	0.34622	-0.89065	0.138	0.0359
grip strength	forelimb and hindlimb grip strength by trial, trial1	-20.663	8.2544	-1.1192	0.123	0.0182
grip strength	forelimb and hindlimb grip strength by trial, trial2	-9.7250	10.055	-0.38079	0.592	0.341
grip strength	forelimb and hindlimb grip strength by trial, trial3	-14.050	12.112	-0.69931	0.522	0.256
grip strength	forelimb grip strength (mean of trials), average	-10.881	4.1024	-1.0362	0.0896	0.0128
grip strength	forelimb grip strength (mean of trials), average normalized to bw	-0.49236	0.21067	-1.0020	0.143	0.0268
grip strength	forelimb grip strength by trial, trial1	-4.7375	6.2270	-0.29922	0.775	0.453
grip strength	forelimb grip strength by trial, trial2	-22.737	6.6640	-1.9516	0.0433	0.00192
grip strength	forelimb grip strength by trial, trial3	-5.8265	7.1542	-0.39645	0.727	0.422
heart weight	heart weight, normalized to body weight	-0.20762	0.12708	-1.2529	0.274	0.108
heart weight	heart weight, weight	-3.3028	3.5761	-0.81308	0.571	0.360
hematology	basophil differential (percent of total WBC)	0.24467	0.081393	2.2385	0.165	0.00480
hematology	calculated hemoglobin (cHGB)	0.83431	0.19950	2.0105	0.00653	0.000177
hematology	eosinophil differential (percent of total WBC)	0.15543	0.31324	0.52896	0.881	0.623
hematology	hematocrit (HCT)	0.95936	0.56471	0.73494	0.357	0.0980
hematology	hemoglobin concentration distribution width (HDW)	0.0074874	0.018111	0.21369	0.855	0.682
hematology	large unstained cells (percent of total WBC)	-0.16268	0.12915	-1.0289	0.570	0.216
hematology	lymphocyte differential (percent of total WBC)	1.1387	0.97355	0.41926	0.504	0.250
hematology	mean corpuscular hemoglobin (CHr)	-0.027001	0.061417	-0.19690	0.835	0.663
hematology	mean platelet volume (MPV)	0.17096	0.079989	0.84829	0.145	0.0394
hematology	mean RBC corpuscular hemoglobin (MCH)	-0.089446	0.17116	-0.36597	0.830	0.604
hematology	mean RBC corpuscular hemoglobin concentration (MCHC)	0.85526	0.37849	1.4252	0.242	0.0300
hematology	mean RBC corpuscular volume (MCV)	-1.6415	0.36654	-2.0074	0.00146	0.0000730
hematology	measured hemoglobin (mHGB)	0.76026	0.21124	1.6378	0.0294	0.000978
hematology	monocyte differential (percent of total WBC)	0.062932	0.27549	0.43273	0.936	0.821
hematology	neutrophil differential (percent of total WBC)	-1.4579	0.75901	-0.66508	0.237	0.0627
hematology	platelet count (PLT; units per volume x 10³)	-18.052	53.167	-0.19531	0.901	0.736
hematology	RBC corpuscular distribution width (RDW)	-0.21482	0.10709	-0.80659	0.231	0.0526
hematology	RBC corpuscular hemoglobin concentration mean (CHCM)	1.2873	0.22437	2.4257	0.000149	0.00000156
hematology	red blood cell count (RBC; per volume x 10⁶)	0.54607	0.14661	1.8493	0.0170	0.000667
hematology	reticulocyte count (Retic; units per volume x 10⁹)	12.379	11.320	0.63240	0.665	0.281
hematology	reticulocyte differential (percent of total RBC)	-0.069216	0.10810	-0.081650	0.799	0.526
hematology	white blood cell count (WBC; units per volume x 10³)	1.1427	0.56095	0.92396	0.163	0.0490
holeboard	number of hole pokes by individual hole number, 20 min test, 1	0.25491	0.51965	0.31664	0.884	0.628
holeboard	number of hole pokes by individual hole number, 20 min test, 2	0.36004	0.42267	0.69208	0.825	0.402
holeboard	number of hole pokes by individual hole number, 20 min test, 3	0.10000	0.41295	0.26033	0.951	0.810
holeboard	number of hole pokes by individual hole number, 20 min test, 4	0.48750	0.70697	0.56256	0.853	0.496
holeboard	number of hole pokes by individual hole number, 20 min test, 5	-0.32999	0.62610	-0.43443	0.907	0.602
holeboard	number of hole pokes by individual hole number, 20 min test, 6	-0.062500	0.25502	-0.12345	0.968	0.808
holeboard	number of hole pokes by individual hole number, 20 min test, 7	1.0886	0.50662	2.1076	0.621	0.0401
holeboard	number of hole pokes by individual hole number, 20 min test, 8	-0.10000	0.41019	-0.065032	0.963	0.809
holeboard	number of hole pokes by individual hole number, 20 min test, 9	-0.012489	0.34451	0.077777	0.994	0.971
holeboard	number of hole pokes by individual hole number, 20 min test, 10	-0.20000	0.27338	-0.49092	0.892	0.470
holeboard	number of hole pokes by individual hole number, 20 min test, 11	-0.36336	0.44828	-0.96294	0.857	0.424
holeboard	number of hole pokes by individual hole number, 20 min test, 12	0.10000	0.36369	0.28729	0.952	0.785
holeboard	number of hole pokes by individual hole number, 20 min test, 13	-0.44866	0.88202	-0.37281	0.881	0.615
holeboard	number of hole pokes by individual hole number, 20 min test, 14	-0.47575	0.48913	-0.68192	0.744	0.339
holeboard	number of hole pokes by individual hole number, 20 min test, 15	-0.36250	0.40917	-0.47433	0.803	0.383
holeboard	number of hole pokes by individual hole number, 20 min test, 16	0.77560	0.83363	0.70552	0.733	0.360
holeboard	total number of hole pokes, 20 min test	1.1022	4.0326	0.25056	0.900	0.787
light / dark	fecal boli count, 20 min test	-0.68787	0.87862	-0.71581	0.785	0.437
light / dark	latency to enter dark zone, 20 min test	88.215	54.941	1.3743	0.551	0.115
light / dark	number of transitions between light and dark zones, 20 min test	-5.1500	7.2355	-0.41594	0.745	0.480
light / dark	percentage of total time in dark zone, 20 min test	2.4306	3.0498	0.55916	0.739	0.429
light / dark	percentage of total time in light zone, 20 min test	-2.4306	3.0498	-0.56233	0.737	0.429
light / dark	time mobile in dark zone, 20 min test	-35.293	9.6953	-1.8623	0.0148	0.000655
light / dark	time mobile in light zone, 20 min test	-0.099150	9.6442	-0.24442	0.996	0.992
light / dark	time spent in dark zone, 20 min test	-56.014	50.863	-0.62030	0.679	0.276
light / dark	time spent in light zone, 20 min test	56.014	50.863	0.62030	0.679	0.276
open field	average speed in center of arena, 20 min test	-0.17651	0.40721	-0.40776	0.870	0.667
open field	average speed in periphery of arena, 20 min test	-0.29325	0.12531	-1.5731	0.101	0.0234
open field	distance traveled habituation ratio, 20 min test	27.588	6.9294	1.9570	0.0114	0.000226
open field	distance traveled in center of arena, 20 min test	-213.68	68.845	-1.6625	0.0348	0.00317
open field	distance traveled in periphery of arena, 20 min test	-202.12	122.48	-1.2362	0.295	0.105
open field	distance traveled slope, 20 min test	26.380	6.5640	2.0148	0.0101	0.000201
open field	distance traveled, 20 min test, 1st 5min	-279.67	67.724	-2.2470	0.00342	0.000141
open field	distance traveled, 20 min test, 2nd 5min	-97.921	52.101	-1.6015	0.226	0.0663
open field	distance traveled, 20 min test, 3rd 5min	-28.594	45.118	-0.76271	0.745	0.529
open field	distance traveled, 20 min test, 4th 5min	-18.763	39.346	-0.68761	0.808	0.636
open field	number of clockwise revolution episodes, 20 min test	-1.1595	1.0746	-1.1458	0.640	0.286
open field	number of counter-clockwise revolution episodes, 20 min test	-1.7300	1.1044	-1.3575	0.387	0.124
open field	number of fecal boli, 20 min test	-2.4017	0.91577	-1.5186	0.164	0.0117
open field	number of rears in 5 min bins, 20 min test, 1st 5min	-4.6948	2.1115	-1.4783	0.167	0.0308
open field	number of rears in 5 min bins, 20 min test, 2nd 5min	1.1512	1.9651	-0.075930	0.777	0.561
open field	number of rears in 5 min bins, 20 min test, 3rd 5min	-4.3041	2.0665	-1.2929	0.203	0.0426
open field	number of rears in 5 min bins, 20 min test, 4th 5min	-3.2098	2.3442	-1.0343	0.447	0.177
open field	percentage of total time in center of arena, 20 min test	-5.0648	1.8664	-1.4247	0.125	0.00916
open field	percentage of total time in center of arena, slope, 20 min test	-1.1782	1.0489	-0.53692	0.730	0.267
open field	percentage of total time in center, habituation ratio, 20 min test	-1.6126	1.0576	-0.73781	0.585	0.134
open field	percentage of total time in corners of arena, 20 min test	9.8011	3.0430	1.9304	0.0493	0.00227
open field	percentage of total time in corners, habituation ratio, 20 min test	2.3256	1.5146	0.75555	0.616	0.131
open field	percentage of total time in corners, slope, 20 min test	0.97418	1.5089	0.17066	0.889	0.522
open field	permanence time in center of arena, 20 min test	-60.778	22.395	-1.4247	0.125	0.00915
open field	permanence time in corners of arena, 20 min test	117.60	36.516	1.9304	0.0493	0.00227
open field	permanence time in periphery of arena, 20 min test	60.754	22.388	1.4247	0.126	0.00916
open field	total distance traveled, 20 min test	-414.47	166.97	-1.5871	0.0781	0.0165
open field	total number of rears, 20 min test	-12.169	6.7845	-1.1968	0.272	0.0792
open field	whole arena average speed, 20 min test	-0.34573	0.13932	-1.5871	0.0784	0.0166
open field	whole arena resting time, 20 min test	29.250	16.373	1.3815	0.223	0.0802
open field	whole arena time spent mobile, 20 min test	-29.362	16.347	-1.6064	0.221	0.0786
open field	whole arena time spent vertical, 20 min test	0.45927	8.3564	-0.078623	0.984	0.956
SHIRPA	locomotor activity (number of squares in the arena the mouse moves into with all four paws in first 30 s of test)	-2.2786	1.4345	-0.80074	0.418	0.123
sleep	differential wake percentages during light and dark phase	0.098508	0.42084	0.55743	0.937	0.817
sleep	mean breath rate during-sleep	0.046340	0.057717	0.59350	0.700	0.429
sleep	mean of sleep bout lengths	2.8399	30.716	0.49885	0.974	0.927
sleep	mean of sleep bout lengths with lights off	36.459	24.686	1.4239	0.525	0.150
sleep	mean of sleep bout lengths with lights on	-30.075	36.752	-0.36455	0.748	0.420
sleep	mean percentage of time sleeping over 24 h periods	3.3075	1.0024	2.0471	0.181	0.00250
sleep	mean percentage of time sleeping with lights on	0.91084	1.2337	0.59350	0.853	0.466
sleep	mean percentage of time spent sleeping with lights off	5.3645	2.0933	1.6984	0.226	0.0156
sleep	peak wake with respect to dark onset median	0.64470	0.70713	0.88904	0.860	0.369
sleep	percentage of time awake one hour before and after light onset	-5.7234	4.5295	-0.46452	0.580	0.216
sleep	sleep data confidence level (<0.6=questionable; 1=good quality)	-0.0016811	0.0027025	0.0	0.938	0.539
startle / PPI	average baseline movement during background noise	0.95708	0.98947	0.68552	0.814	0.337
startle / PPI	average of each corrected maximum percent pre-pulse inhibition value	0.082691	0.68506	0.67141	0.958	0.904
startle / PPI	average of each corrected percent pre-pulse inhibition value	-0.096772	0.057130	-1.0486	0.399	0.0956
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-11.614	6.1351	-1.2170	0.798	0.0633
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-6.8534	6.9306	-0.70695	0.680	0.327
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-6.2300	5.5275	-0.68907	0.563	0.264
startle / PPI	average startle response to full pulse (120 dB)	11.202	28.188	0.48414	0.858	0.693
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	32.402	27.480	0.81947	0.484	0.243
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	13.334	25.790	0.48414	0.764	0.607
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	15.042	22.221	0.55962	0.685	0.501
startle / PPI	average startle response to pre-pulse, 74dB sound pressure level	0.91616	1.0873	0.67493	0.832	0.403
startle / PPI	average startle response to pre-pulse, 78dB sound pressure level	-0.24417	1.5608	-0.16112	0.976	0.876
startle / PPI	average startle response to pre-pulse, 82dB sound pressure level	0.16759	1.4303	-0.091903	0.977	0.907
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-0.12675	0.065840	-1.1122	0.751	0.0591
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-0.082050	0.075278	-0.74441	0.616	0.280
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-0.080120	0.070558	-0.78046	0.523	0.261
startle / PPI	corrected average startle response to full pulse (120 dB) minus average baseline movement during background noise	10.340	28.274	0.47158	0.873	0.716
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 74dB sound pressure level	31.448	27.731	0.78849	0.497	0.261
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 78dB sound pressure level	13.560	25.689	0.49520	0.761	0.600
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 82dB sound pressure level	14.883	22.325	0.56454	0.695	0.508
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-0.15147	0.072787	-1.2025	0.700	0.0419
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-0.095120	0.078977	-0.81906	0.580	0.233
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	0.50434	2.0115	2.2654	0.921	0.803
startle / PPI	corrected maximum startle response to full pulse (120 dB) minus maximum baseline movement during background noise	18.509	101.08	0.31256	0.942	0.855
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 74dB sound pressure level	107.97	102.25	0.73603	0.535	0.295
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 78dB sound pressure level	39.725	96.801	0.40676	0.813	0.683
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 82dB sound pressure level	38.439	84.226	0.44667	0.787	0.650
startle / PPI	maximum baseline movement during background noise	1.3267	2.0016	0.49679	0.855	0.510
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-14.402	6.9481	-1.3271	0.767	0.0426
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-8.4428	7.5060	-0.81751	0.627	0.265
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-5.9338	6.2012	-0.67141	0.633	0.343
startle / PPI	maximum startle response to full pulse (120 dB)	19.845	100.89	0.31993	0.937	0.845
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	109.69	101.51	0.74525	0.525	0.284
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	38.803	97.247	0.39159	0.817	0.691
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	39.007	83.828	0.43894	0.784	0.643
startle / PPI	maximum startle response to pre-pulse, 74dB sound pressure level	1.8954	2.4804	0.65223	0.832	0.448
startle / PPI	maximum startle response to pre-pulse, 78dB sound pressure level	-1.1233	4.2735	-0.29349	0.971	0.794
startle / PPI	maximum startle response to pre-pulse, 82dB sound pressure level	0.78125	3.3070	-0.017515	0.934	0.814

MULTIPLE (CATEGORICAL) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

Procedure	JaxKOMP-EAP Trait	Trait Effect	P-value
electroretinography	blind eyes, left	0.0 %	1.0
electroretinography	blind eyes, right	0.0 %	1.0
eye morphology	anterior chamber depth	1.0 %	1.0
eye morphology	bulging eye	1.0 %	1.00
eye morphology	cornea	3.0 %	1.00
eye morphology	cornea opacity	6.0 %	0.249
eye morphology	cornea vascularization	2.0 %	1.00
eye morphology	corneal deposits	1.0 %	1.00
eye morphology	corneal mineralization	1.0 %	1.00
eye morphology	corneal scleralization	2.0 %	1.00
eye morphology	corneal ulcer	1.0 %	1.00
eye morphology	eye closure	1.0 %	1.0
eye morphology	eye hemorrhage or blood presence	1.0 %	1.00
eye morphology	eyelid morphology	1.0 %	1.0
eye morphology	eyes (present, absent)	0.0 %	1.0
eye morphology	fusion between cornea and lens	3.0 %	1.00
eye morphology	iris pigmentation	2.0 %	1.00
eye morphology	iris transillumination	1.0 %	1.00
eye morphology	irispupil	3.0 %	1.00
eye morphology	lacrimation	6.0 %	0.106
eye morphology	lens	15.0 %	0.181
eye morphology	lens opacity	7.0 %	1.00
eye morphology	narrow eye opening	1.0 %	1.0
eye morphology	optic disc	3.0 %	1.00
eye morphology	persistence of hyaloid vascular system	14.0 %	0.232
eye morphology	pupil dilation	2.0 %	1.0
eye morphology	pupil light response	2.0 %	1.00
eye morphology	pupil position	5.0 %	0.461
eye morphology	pupil shape	5.0 %	0.342
eye morphology	retina	13.0 %	1.0
eye morphology	retinal blood vessels	3.0 %	1.0
eye morphology	retinal blood vessels pattern	4.0 %	1.00
eye morphology	retinal blood vessels structure	3.0 %	1.00
eye morphology	retinal pigmentation	13.0 %	1.0
eye morphology	retinal structure	3.0 %	1.00
eye morphology	synechia	3.0 %	1.00
eye morphology	vitreous	3.0 %	1.00
SHIRPA	activity body position	1.0 %	1.00
SHIRPA	aggression	1.0 %	1.00
SHIRPA	body length	0.0 %	1.0
SHIRPA	body position	0.0 %	1.00
SHIRPA	body thickness	0.0 %	1.00
SHIRPA	coat color abdomen	4.0 %	1.00
SHIRPA	coat color back	0.0 %	1.00
SHIRPA	coat color head	0.0 %	1.0
SHIRPA	coat color pattern abdomen	1.0 %	1.00
SHIRPA	coat color pattern back	0.0 %	1.00
SHIRPA	coat color pattern head	0.0 %	1.0
SHIRPA	coat hair abdomen texture appearance	2.0 %	1.0
SHIRPA	coat hair back texture appearance	0.0 %	1.0
SHIRPA	coat hair distribution abdomen	1.0 %	1.0
SHIRPA	coat hair distribution back	0.0 %	1.00
SHIRPA	coat hair distribution head	1.0 %	1.0
SHIRPA	coat hair head texture appearance	0.0 %	1.0
SHIRPA	contact righting	5.0 %	1.00
SHIRPA	ear morphology	0.0 %	1.0
SHIRPA	fat distribution	0.0 %	1.0
SHIRPA	forelimb digit number	0.0 %	1.0
SHIRPA	forelimb digit position	0.0 %	1.0
SHIRPA	forelimb digit shape	0.0 %	1.0
SHIRPA	forelimb digit size	0.0 %	1.0
SHIRPA	forelimb footpads	0.0 %	1.0
SHIRPA	forelimb nail length	0.0 %	1.0
SHIRPA	forelimb nail number	0.0 %	1.0
SHIRPA	forelimb nail position	0.0 %	1.0
SHIRPA	forelimb nail shape	0.0 %	1.0
SHIRPA	forelimbs position	0.0 %	1.0
SHIRPA	forelimbs shape	0.0 %	1.0
SHIRPA	forelimbs size	0.0 %	1.0
SHIRPA	forepaw position	0.0 %	1.0
SHIRPA	forepaw shape	0.0 %	1.0
SHIRPA	forepaw size	0.0 %	1.0
SHIRPA	gait (fluidity)	0.0 %	1.0
SHIRPA	genitalia morphology	0.0 %	1.00
SHIRPA	genitalia presence	0.0 %	1.0
SHIRPA	genitalia size	0.0 %	1.00
SHIRPA	head bobbing	0.0 %	1.0
SHIRPA	head morphology	0.0 %	1.0
SHIRPA	head size	0.0 %	1.0
SHIRPA	hindlimb digit number	0.0 %	1.0
SHIRPA	hindlimb digit position	0.0 %	1.0
SHIRPA	hindlimb digit shape	0.0 %	1.00
SHIRPA	hindlimb digit size	0.0 %	1.00
SHIRPA	hindlimb nail length	0.0 %	1.0
SHIRPA	hindlimb nail number	0.0 %	1.0
SHIRPA	hindlimb nail position	0.0 %	1.0
SHIRPA	hindlimb nail shape	0.0 %	1.0
SHIRPA	hindlimbs footpads	0.0 %	1.0
SHIRPA	hindlimbs position	0.0 %	1.0
SHIRPA	hindlimbs shape	0.0 %	1.0
SHIRPA	hindlimbs size	0.0 %	1.0
SHIRPA	hindpaw position	0.0 %	1.0
SHIRPA	hindpaw shape	0.0 %	1.0
SHIRPA	hindpaw size	0.0 %	1.0
SHIRPA	limb grasp	26.0 %	0.00337
SHIRPA	lower lip morphology	0.0 %	1.0
SHIRPA	lower teeth appearance	0.0 %	1.0
SHIRPA	mouth morphology	0.0 %	1.0
SHIRPA	salivation	0.0 %	1.0
SHIRPA	skin color back paws	0.0 %	1.0
SHIRPA	skin color ear	0.0 %	1.0
SHIRPA	skin color front paws	0.0 %	1.0
SHIRPA	skin color snout	0.0 %	1.0
SHIRPA	skin color tail	0.0 %	1.0
SHIRPA	skin color whole body	0.0 %	1.0
SHIRPA	skin texture back paw	0.0 %	1.0
SHIRPA	skin texture ear	0.0 %	1.0
SHIRPA	skin texture front paws	0.0 %	1.0
SHIRPA	skin texture snout	0.0 %	1.0
SHIRPA	skin texture tail	0.0 %	1.0
SHIRPA	skin texture whole body	0.0 %	1.00
SHIRPA	snout size	0.0 %	1.0
SHIRPA	startle response	0.0 %	1.0
SHIRPA	tail curvature	0.0 %	1.00
SHIRPA	tail elevation	1.0 %	1.0
SHIRPA	tail length	0.0 %	1.0
SHIRPA	tail morphology	0.0 %	1.00
SHIRPA	tail presence	0.0 %	1.0
SHIRPA	tail shape	0.0 %	1.0
SHIRPA	tail thickness	0.0 %	1.0
SHIRPA	teeth presence	0.0 %	1.0
SHIRPA	transfer arousal	1.0 %	1.0
SHIRPA	tremor	0.0 %	1.00
SHIRPA	trunk curl	0.0 %	1.00
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	0.0 %	1.0
SHIRPA	upper lip morphology	0.0 %	1.0
SHIRPA	upper teeth appearance	0.0 %	1.0
SHIRPA	vibrissae appearance	1.0 %	1.0
SHIRPA	vibrissae presence	2.0 %	1.0
SHIRPA	vocalization	2.0 %	1.0

GENOTYPE CORRELATION PLOT

Correlate Gtpbp10^{tm1b(KOMP)Mbp} -/- with genotype:

This genotype correlation visualization can include both EAP and LAP measures.