MPD: JaxKOMP-EAP genotype: Adar<sup>tm1b(EUCOMM)Wtsi</sup> -/+

JaxKOMP-EAP effect sizes: Adar^{tm1b(EUCOMM)Wtsi} -/+ Gene Adar

MULTIPLE (NUMERIC) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

Procedure	JaxKOMP-EAP Trait	Trait Effect	Trait Effect SE	Trait Effect RankZ	Adjusted p-value	Unadjusted p-value
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 6 kHz pip	-0.19231	1.8943	-0.33459	0.977	0.921
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 12 kHz pip	-2.9567	2.4171	-0.65549	0.712	0.247
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 18 kHz pip	-1.1779	2.2442	-0.45160	0.865	0.610
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 24 kHz pip	-0.31250	3.2858	-0.17756	0.977	0.926
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 30 kHz pip	-5.2644	3.9849	-0.82693	0.604	0.213
body composition	body length	-0.22938	0.060641	-1.6904	0.0209	0.00117
body composition	body weight (at time of DXA)	-0.19437	0.68742	-0.064860	0.889	0.780
body composition	bone area, whole body scan, head excluded	-0.77318	0.19009	-2.1928	0.0133	0.000601
body composition	bone mineral content of whole body scan, head excluded	-0.049662	0.011889	-1.9877	0.0127	0.000465
body composition	bone mineral content to body weight ratio	-0.0019565	0.00063636	-1.9060	0.0544	0.00575
body composition	bone mineral density of whole body scan, head excluded	-0.0017402	0.00059862	-1.5881	0.0919	0.00872
body composition	fat tissue mass of whole body scan, head excluded	0.41226	0.31754	0.65914	0.450	0.209
body composition	fat tissue mass to body weight ratio	0.022315	0.013678	0.97838	0.307	0.118
body composition	lean tissue mass of whole body scan, head excluded	-0.61450	0.33171	-1.2991	0.323	0.0788
body composition	lean tissue mass to body weight ratio	-0.016006	0.011389	-0.89336	0.420	0.175
body composition	percent fat, whole body scan, head excluded	2.1281	1.2975	1.0029	0.311	0.116
body composition	ratio of soft-tissue attenuation coefficients	-0.0023625	0.0014424	-1.0083	0.311	0.116
body composition	tissue area	-0.56280	0.21662	-1.5237	0.134	0.0172
body composition	total tissue mass, whole body scan, head excluded	-0.20225	0.22327	-0.68136	0.626	0.376
clinical blood chemistry	alanine transaminase (plasma ALT)	-52.744	40.224	-2.6557	0.581	0.205
clinical blood chemistry	albumin (plasma Alb)	-0.052326	0.41406	-0.031374	0.970	0.901
clinical blood chemistry	alkaline phosphatase (plasma ALP)	5.2310	4.1747	0.45051	0.480	0.225
clinical blood chemistry	aspartate transaminase (plasma AST)	-5.9419	29.932	-0.29931	0.956	0.845
clinical blood chemistry	aspartate transaminase to alanine transaminase ratio (plasma AST:ALT)	0.47486	0.22442	1.2738	0.355	0.0478
clinical blood chemistry	blood urea nitrogen (BUN)	2.2149	1.5317	0.86389	0.409	0.165
clinical blood chemistry	calcium (plasma Ca)	-0.010445	0.087326	0.29053	0.949	0.906
clinical blood chemistry	carbon dioxide (plasma CO₂)	1.0721	0.58874	0.71568	0.306	0.0836
clinical blood chemistry	chloride (plasma Cl)	-0.019767	0.71261	-0.091015	0.988	0.978
clinical blood chemistry	glucose (plasma GLU, no fast)	-60.715	18.441	-1.6380	0.0288	0.00430
clinical blood chemistry	HDL cholesterol (plasma HDL)	6.2072	3.8742	1.0871	0.389	0.126
clinical blood chemistry	HDL cholesterol to total cholesterol ratio	0.0036570	0.021233	0.067664	0.967	0.865
clinical blood chemistry	iron (plasma Fe)	-0.013823	0.0067690	-0.87077	0.243	0.0553
clinical blood chemistry	non-esterified fatty acids (plasma NEFA)	-0.063571	0.070279	-0.47742	0.641	0.377
clinical blood chemistry	phosphorus (plasma phosphate)	-0.16047	0.36113	-0.31209	0.837	0.662
clinical blood chemistry	potassium (plasma K)	0.11325	0.26040	-0.52166	0.765	0.669
clinical blood chemistry	sodium (plasma Na)	1.4477	0.72115	0.42549	0.122	0.0584
clinical blood chemistry	total bilirubin (plasma TBIL)	-0.0096512	0.013491	-0.72250	0.776	0.483
clinical blood chemistry	total cholesterol (plasma CHOL, no fast)	6.1650	3.8478	0.79512	0.401	0.126
clinical blood chemistry	total protein (plasma TP)	-0.69462	0.52712	-0.62860	0.488	0.204
clinical blood chemistry	triglyceride (plasma TG, no fast)	-4.4107	11.922	-0.0042922	0.871	0.716
ECT	applied stimulus (current), by day, day 2	0.52339	0.32448	1.1086	0.408	0.123
ECT	applied stimulus (current), by day, day 3	0.23673	0.16481	0.37248	0.461	0.167
ECT	behavior following applied stimulus (current), by day, day 1	-0.99563	0.48602	-1.7002	0.290	0.0554
ECT	behavior following applied stimulus (current), by day, day 3	-0.62894	0.26033	-1.6766	0.502	0.0259
ECT	stimulus level (current) required for minimal clonic forebrain seizure (score of 3 or higher)	0.81879	0.34299	1.7087	0.169	0.0282
EKG	duration of PQ interval	1.2260	1.1311	1.3971	0.824	0.293
EKG	duration of PR interval	1.2249	1.2923	1.3556	0.877	0.356
EKG	duration of QRS interval	-0.0037182	0.48263	-0.15782	0.999	0.994
EKG	duration of QT interval	0.31957	1.5171	0.46339	0.979	0.836
EKG	duration of QTC interval, calculated by dividing QT interval by square root of preceding RR interval	-0.16575	1.1128	-0.13542	0.991	0.883
EKG	duration of RR interval	1.4464	2.6636	1.0012	0.849	0.594
EKG	duration of ST interval	0.29393	1.1379	0.51564	0.960	0.799
EKG	heart rate coefficient of variation (signal intensity)	-3.6904	2.6160	-2.5883	0.841	0.175
EKG	heart rate variability, mean of differences between sequential beats; beats per min	-29.023	20.386	-2.8186	0.853	0.172
EKG	heart rate, beats per min	-17.045	22.366	-1.3206	0.786	0.456
EKG	mean R amplitude, mean amplitude of signal measured from isoelectric line to peak of QRS	0.099145	0.057221	0.66126	0.422	0.101
EKG	mean SR amplitude, mean amplitude of signal measured from signal minimum line to peak of QRS	0.11618	0.085021	0.58294	0.550	0.190
EKG	number of signals	5.2446	5.4538	0.97820	0.823	0.349
EKG	proportion of number pairs of successive beat-to-beat intervals that exceed 50 ms	-4.1989	3.8270	-0.70026	0.817	0.287
EKG	QT dispersion, measured as inter-lead variability of QT intervals	1.0685	2.8636	0.34739	0.968	0.713
EKG	QTc dispersion, calculated as rate-corrected QT dispersion	-0.47378	3.4613	-0.11714	0.986	0.893
EKG	root mean square of successive differences of neighboring RR intervals	-3.5355	2.6821	-1.7212	0.843	0.204
glucose tolerance test	amount glucose injected	5.2895	1.9959	1.6095	0.182	0.0158
glucose tolerance test	plasma glucose, 0min	15.927	5.1785	1.3024	0.0396	0.00597
glucose tolerance test	plasma glucose, 15min	59.875	38.750	1.6359	0.436	0.138
glucose tolerance test	plasma glucose, 30min	81.500	33.659	2.0713	0.173	0.0251
glucose tolerance test	plasma glucose, 60min	56.813	28.262	2.0483	0.282	0.0581
glucose tolerance test	plasma glucose, 120min	14.938	11.213	0.88182	0.509	0.198
grip strength	body weight (at time of grip strength test)	-0.29087	0.67734	-0.072593	0.808	0.672
grip strength	forelimb and hindlimb grip strength (mean of trials), average	-42.873	9.3957	-2.4308	0.00335	0.000169
grip strength	forelimb and hindlimb grip strength (mean of trials), average normalized to bw	-2.7315	0.54275	-2.9221	0.00208	0.0000555
grip strength	forelimb and hindlimb grip strength by trial, trial1	-32.143	13.904	-1.7785	0.175	0.0305
grip strength	forelimb and hindlimb grip strength by trial, trial2	-72.887	16.001	-3.2488	0.00958	0.000155
grip strength	forelimb and hindlimb grip strength by trial, trial3	-24.090	7.8720	-1.2737	0.0586	0.00594
grip strength	forelimb grip strength (mean of trials), average	-4.4676	4.6428	-0.29922	0.605	0.347
grip strength	forelimb grip strength (mean of trials), average normalized to bw	-0.29728	0.18974	-0.51576	0.374	0.131
grip strength	forelimb grip strength by trial, trial1	-18.101	5.0520	-1.6465	0.0465	0.00175
grip strength	forelimb grip strength by trial, trial2	0.57960	5.5966	0.27500	0.967	0.918
grip strength	forelimb grip strength by trial, trial3	-4.3964	6.9052	-0.23300	0.785	0.531
heart weight	heart weight, normalized to body weight	-0.61264	0.26762	-2.4301	0.140	0.0337
heart weight	heart weight, weight	-14.309	6.5612	-2.1820	0.170	0.0413
hematology	basophil differential (percent of total WBC)	0.12151	0.043770	1.5171	0.220	0.0120
hematology	calculated hemoglobin (cHGB)	0.34528	0.18731	0.82294	0.296	0.0809
hematology	eosinophil differential (percent of total WBC)	-0.28444	0.24886	-0.69393	0.647	0.267
hematology	hematocrit (HCT)	0.87558	0.70631	0.63302	0.526	0.230
hematology	hemoglobin concentration distribution width (HDW)	0.0073837	0.021116	0.20836	0.878	0.730
hematology	large unstained cells (percent of total WBC)	0.13663	0.090688	0.87833	0.489	0.148
hematology	lymphocyte differential (percent of total WBC)	-1.2570	1.3670	-0.58531	0.611	0.369
hematology	mean corpuscular hemoglobin (CHr)	-0.20523	0.064874	-1.4920	0.0358	0.00512
hematology	mean platelet volume (MPV)	-0.10712	0.19082	-0.85025	0.775	0.581
hematology	mean RBC corpuscular hemoglobin (MCH)	-0.62965	0.17496	-1.2694	0.0466	0.00191
hematology	mean RBC corpuscular hemoglobin concentration (MCHC)	-0.71977	0.43666	-1.0759	0.442	0.116
hematology	mean RBC corpuscular volume (MCV)	-0.92616	0.26730	-1.4040	0.0215	0.00259
hematology	measured hemoglobin (mHGB)	-0.060465	0.32210	-0.38760	0.934	0.853
hematology	monocyte differential (percent of total WBC)	0.43372	0.19595	1.4378	0.298	0.0393
hematology	neutrophil differential (percent of total WBC)	0.71919	1.2153	0.38665	0.753	0.561
hematology	platelet count (PLT; units per volume x 10³)	49.273	74.010	0.71186	0.796	0.514
hematology	RBC corpuscular distribution width (RDW)	0.45308	0.10999	1.3845	0.0165	0.000644
hematology	RBC corpuscular hemoglobin concentration mean (CHCM)	0.15698	0.23687	0.39848	0.744	0.515
hematology	red blood cell count (RBC; per volume x 10⁶)	0.43546	0.13970	1.5016	0.0721	0.00567
hematology	reticulocyte count (Retic; units per volume x 10⁹)	-9.2181	15.334	-0.32352	0.838	0.555
hematology	reticulocyte differential (percent of total RBC)	-0.22391	0.12940	-0.75915	0.440	0.0998
hematology	white blood cell count (WBC; units per volume x 10³)	2.3464	0.90905	1.6758	0.0833	0.0183
light / dark	fecal boli count, 20 min test	1.1875	0.79986	1.2751	0.567	0.152
light / dark	latency to enter dark zone, 20 min test	-38.070	31.565	-0.82783	0.662	0.241
light / dark	number of transitions between light and dark zones, 20 min test	-16.563	7.7511	-1.5650	0.255	0.0440
light / dark	percentage of total time in dark zone, 20 min test	2.9130	3.7269	0.64674	0.746	0.443
light / dark	percentage of total time in light zone, 20 min test	-2.9130	3.7269	-0.64841	0.744	0.443
light / dark	time mobile in dark zone, 20 min test	-16.015	14.454	-1.0436	0.578	0.280
light / dark	time mobile in light zone, 20 min test	-8.6057	12.035	-0.86261	0.724	0.482
light / dark	time spent in dark zone, 20 min test	69.315	50.734	1.2766	0.618	0.186
light / dark	time spent in light zone, 20 min test	-69.315	50.734	-1.2766	0.618	0.186
open field	average speed in center of arena, 20 min test	-1.2566	0.38088	-2.2819	0.0671	0.00342
open field	average speed in periphery of arena, 20 min test	-0.23156	0.10901	-1.3956	0.157	0.0463
open field	distance traveled habituation ratio, 20 min test	-0.70402	7.4231	-0.014098	0.964	0.925
open field	distance traveled in center of arena, 20 min test	-19.894	84.544	-0.50463	0.900	0.816
open field	distance traveled in periphery of arena, 20 min test	-267.55	118.43	-1.5156	0.150	0.0352
open field	distance traveled slope, 20 min test	-0.24884	7.1754	0.031556	0.995	0.973
open field	distance traveled, 20 min test, 1st 5min	-13.286	51.781	-0.45939	0.916	0.800
open field	distance traveled, 20 min test, 2nd 5min	-131.98	59.854	-1.8888	0.166	0.0393
open field	distance traveled, 20 min test, 3rd 5min	-130.76	43.530	-1.7676	0.0515	0.00676
open field	distance traveled, 20 min test, 4th 5min	-40.116	62.401	-0.93194	0.746	0.527
open field	number of clockwise revolution episodes, 20 min test	0.59120	1.2350	-0.052413	0.864	0.637
open field	number of counter-clockwise revolution episodes, 20 min test	-1.1786	1.1521	-1.0693	0.602	0.318
open field	number of fecal boli, 20 min test	-0.42411	1.1746	-0.047042	0.873	0.722
open field	number of rears in 5 min bins, 20 min test, 1st 5min	-3.6741	1.8993	-1.2188	0.255	0.0666
open field	number of rears in 5 min bins, 20 min test, 2nd 5min	-5.8427	2.8858	-1.6899	0.250	0.0565
open field	number of rears in 5 min bins, 20 min test, 3rd 5min	-5.9046	1.7309	-1.6015	0.0400	0.00277
open field	number of rears in 5 min bins, 20 min test, 4th 5min	-1.4354	3.3611	-0.63744	0.833	0.674
open field	percentage of total time in center of arena, 20 min test	1.7523	2.9338	0.20757	0.816	0.557
open field	percentage of total time in center of arena, slope, 20 min test	0.59238	1.9213	0.45939	0.946	0.761
open field	percentage of total time in center, habituation ratio, 20 min test	1.3186	1.9404	0.82906	0.850	0.504
open field	percentage of total time in corners of arena, 20 min test	3.8872	4.8128	1.0027	0.708	0.428
open field	percentage of total time in corners, habituation ratio, 20 min test	-1.2634	3.8049	-0.88330	0.949	0.743
open field	percentage of total time in corners, slope, 20 min test	-0.78049	3.7381	-0.66065	0.965	0.837
open field	permanence time in center of arena, 20 min test	21.010	35.208	0.20757	0.816	0.557
open field	permanence time in corners of arena, 20 min test	46.658	57.755	1.0027	0.708	0.428
open field	permanence time in periphery of arena, 20 min test	-21.080	35.210	-0.20757	0.815	0.556
open field	total distance traveled, 20 min test	-305.01	149.58	-1.3343	0.178	0.0549
open field	total number of rears, 20 min test	-16.920	8.1752	-1.4746	0.208	0.0517
open field	whole arena average speed, 20 min test	-0.25216	0.12510	-1.3278	0.182	0.0575
open field	whole arena resting time, 20 min test	22.729	15.924	1.1886	0.348	0.169
open field	whole arena time spent mobile, 20 min test	-22.770	15.917	-1.4100	0.351	0.168
open field	whole arena time spent vertical, 20 min test	-24.834	9.2223	-1.8143	0.125	0.0136
plasma chemistry analysis	free fatty acids (plasma)	0.11375	0.11257	1.3254	0.459	0.323
plasma chemistry analysis	plasma cholesterol	4.5275	3.6982	0.94705	0.424	0.234
plasma chemistry analysis	plasma glucose (4h fast)	-17.719	9.3347	-0.94705	0.233	0.0709
plasma chemistry analysis	plasma HDL	3.6126	3.5637	0.78626	0.539	0.322
plasma chemistry analysis	plasma triglycerides (4h fast)	2.5268	6.5447	0.85760	0.812	0.703
rotarod	learning difference on accelerating rotarod (4-40 rpm/5 min) over 5 trials	-5.6562	15.495	-0.21273	0.927	0.719
rotarod	learning slope on accelerating rotarod (4-40 rpm/5 min) over 5 trials	-1.2812	4.4198	-0.053932	0.942	0.775
rotarod	mean duration on accelerating rotarod (4-40 rpm/5 min) over 5 trials	13.008	10.384	1.4504	0.581	0.225
rotarod	mean latency to fall off accelerating rotarod (4-40 rpm/ 5 min) over 5 trials	4.125	18.639	0.51617	0.940	0.827
SHIRPA	locomotor activity (number of squares in the arena the mouse moves into with all four paws in first 30 s of test)	-2.1094	1.8621	-0.70865	0.587	0.270
tail suspension	duration of immobility, 5 min test	-9.5011	15.850	-1.2242	0.755	0.555
tail suspension	latency to immobility, 5 min test	0.18750	1.4017	0.36963	0.976	0.895

MULTIPLE (CATEGORICAL) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

Procedure	JaxKOMP-EAP Trait	Sex	Trait Effect	P-value
eye morphology	anterior chamber depth	females	1.0 %	1.0
eye morphology	anterior chamber depth	males	0.0 %	1.0
eye morphology	anterior chamber depth	both	1.0 %	1.0
eye morphology	bulging eye	females	1.0 %	1.0
eye morphology	bulging eye	males	0.0 %	1.0
eye morphology	bulging eye	both	1.0 %	1.00
eye morphology	cornea	females	4.0 %	1.0
eye morphology	cornea	males	2.0 %	1.0
eye morphology	cornea	both	3.0 %	1.00
eye morphology	cornea opacity	females	9.0 %	0.359
eye morphology	cornea opacity	males	1.0 %	1.0
eye morphology	cornea opacity	both	4.0 %	0.428
eye morphology	cornea vascularization	females	3.0 %	1.0
eye morphology	cornea vascularization	males	1.0 %	1.0
eye morphology	cornea vascularization	both	2.0 %	1.00
eye morphology	corneal deposits	females	2.0 %	1.0
eye morphology	corneal deposits	males	1.0 %	1.0
eye morphology	corneal deposits	both	1.0 %	1.00
eye morphology	corneal mineralization	females	2.0 %	1.0
eye morphology	corneal mineralization	males	1.0 %	1.0
eye morphology	corneal mineralization	both	1.0 %	1.00
eye morphology	corneal scleralization	females	3.0 %	1.00
eye morphology	corneal scleralization	males	1.0 %	1.0
eye morphology	corneal scleralization	both	2.0 %	1.00
eye morphology	corneal ulcer	females	1.0 %	1.0
eye morphology	corneal ulcer	males	1.0 %	1.0
eye morphology	corneal ulcer	both	1.0 %	1.00
eye morphology	eye closure	females	1.0 %	1.00
eye morphology	eye closure	males	0.0 %	1.0
eye morphology	eye closure	both	1.0 %	1.0
eye morphology	eye hemorrhage or blood presence	females	2.0 %	1.00
eye morphology	eye hemorrhage or blood presence	males	1.0 %	1.0
eye morphology	eye hemorrhage or blood presence	both	1.0 %	1.00
eye morphology	eyelid morphology	females	1.0 %	1.0
eye morphology	eyelid morphology	males	0.0 %	1.0
eye morphology	eyelid morphology	both	1.0 %	1.0
eye morphology	eyes (present, absent)	females	1.0 %	1.0
eye morphology	eyes (present, absent)	males	0.0 %	1.0
eye morphology	eyes (present, absent)	both	0.0 %	1.0
eye morphology	fusion between cornea and lens	females	4.0 %	1.00
eye morphology	fusion between cornea and lens	males	2.0 %	1.0
eye morphology	fusion between cornea and lens	both	3.0 %	1.00
eye morphology	iris pigmentation	females	2.0 %	1.0
eye morphology	iris pigmentation	males	1.0 %	1.0
eye morphology	iris pigmentation	both	2.0 %	1.00
eye morphology	iris transillumination	females	2.0 %	1.00
eye morphology	iris transillumination	males	1.0 %	1.0
eye morphology	iris transillumination	both	1.0 %	1.00
eye morphology	irispupil	females	4.0 %	1.00
eye morphology	irispupil	males	3.0 %	1.0
eye morphology	irispupil	both	3.0 %	1.00
eye morphology	lacrimation	females	3.0 %	1.0
eye morphology	lacrimation	males	25.0 %	0.00238
eye morphology	lacrimation	both	12.0 %	0.0156
eye morphology	lens	females	10.0 %	1.00
eye morphology	lens	males	12.0 %	0.178
eye morphology	lens	both	6.0 %	0.393
eye morphology	lens opacity	females	9.0 %	1.0
eye morphology	lens opacity	males	6.0 %	1.0
eye morphology	lens opacity	both	7.0 %	1.00
eye morphology	narrow eye opening	females	2.0 %	1.0
eye morphology	narrow eye opening	males	1.0 %	1.0
eye morphology	narrow eye opening	both	1.0 %	1.0
eye morphology	optic disc	females	12.0 %	0.0709
eye morphology	optic disc	males	2.0 %	1.0
eye morphology	optic disc	both	6.0 %	0.138
eye morphology	persistence of hyaloid vascular system	females	14.0 %	1.0
eye morphology	persistence of hyaloid vascular system	males	11.0 %	0.333
eye morphology	persistence of hyaloid vascular system	both	3.0 %	0.790
eye morphology	pupil dilation	females	2.0 %	1.0
eye morphology	pupil dilation	males	1.0 %	1.0
eye morphology	pupil dilation	both	2.0 %	1.0
eye morphology	pupil light response	females	2.0 %	1.00
eye morphology	pupil light response	males	1.0 %	1.0
eye morphology	pupil light response	both	2.0 %	1.00
eye morphology	pupil position	females	11.0 %	0.301
eye morphology	pupil position	males	3.0 %	1.0
eye morphology	pupil position	both	5.0 %	0.461
eye morphology	pupil shape	females	3.0 %	1.00
eye morphology	pupil shape	males	2.0 %	1.0
eye morphology	pupil shape	both	3.0 %	1.00
eye morphology	retina	females	10.0 %	1.0
eye morphology	retina	males	16.0 %	1.0
eye morphology	retina	both	13.0 %	1.0
eye morphology	retinal blood vessels	females	4.0 %	1.0
eye morphology	retinal blood vessels	males	2.0 %	1.0
eye morphology	retinal blood vessels	both	3.0 %	1.0
eye morphology	retinal blood vessels pattern	females	20.0 %	0.0116
eye morphology	retinal blood vessels pattern	males	2.0 %	1.0
eye morphology	retinal blood vessels pattern	both	9.0 %	0.0227
eye morphology	retinal blood vessels structure	females	4.0 %	1.00
eye morphology	retinal blood vessels structure	males	2.0 %	1.0
eye morphology	retinal blood vessels structure	both	3.0 %	1.00
eye morphology	retinal pigmentation	females	10.0 %	0.522
eye morphology	retinal pigmentation	males	14.0 %	1.0
eye morphology	retinal pigmentation	both	7.0 %	0.738
eye morphology	retinal structure	females	4.0 %	1.00
eye morphology	retinal structure	males	2.0 %	1.0
eye morphology	retinal structure	both	3.0 %	1.00
eye morphology	synechia	females	4.0 %	1.0
eye morphology	synechia	males	2.0 %	1.0
eye morphology	synechia	both	3.0 %	1.00
eye morphology	vitreous	females	4.0 %	1.00
eye morphology	vitreous	males	2.0 %	1.0
eye morphology	vitreous	both	3.0 %	1.00
rotarod	outcome of accelerating rotarod (4-40 rpm/ 5 min) over 5 trials	females	0.0 %	1.0
rotarod	outcome of accelerating rotarod (4-40 rpm/ 5 min) over 5 trials	males	0.0 %	1.0
rotarod	outcome of accelerating rotarod (4-40 rpm/ 5 min) over 5 trials	both	0.0 %	1.0
rotarod	trial number	females	0.0 %	1.0
rotarod	trial number	males	0.0 %	1.0
rotarod	trial number	both	0.0 %	1.0
SHIRPA	activity body position	females	1.0 %	1.0
SHIRPA	activity body position	males	2.0 %	1.0
SHIRPA	activity body position	both	1.0 %	1.00
SHIRPA	aggression	females	0.0 %	1.00
SHIRPA	aggression	males	1.0 %	1.0
SHIRPA	aggression	both	1.0 %	1.0
SHIRPA	body length	females	0.0 %	1.0
SHIRPA	body length	males	0.0 %	1.00
SHIRPA	body length	both	0.0 %	1.00
SHIRPA	body position	females	0.0 %	1.0
SHIRPA	body position	males	1.0 %	1.0
SHIRPA	body position	both	0.0 %	1.0
SHIRPA	body thickness	females	1.0 %	1.0
SHIRPA	body thickness	males	0.0 %	1.0
SHIRPA	body thickness	both	0.0 %	1.0
SHIRPA	coat color abdomen	females	3.0 %	1.00
SHIRPA	coat color abdomen	males	9.0 %	0.256
SHIRPA	coat color abdomen	both	3.0 %	0.440
SHIRPA	coat color back	females	0.0 %	1.0
SHIRPA	coat color back	males	0.0 %	1.00
SHIRPA	coat color back	both	0.0 %	1.00
SHIRPA	coat color head	females	0.0 %	1.0
SHIRPA	coat color head	males	0.0 %	1.00
SHIRPA	coat color head	both	0.0 %	1.0
SHIRPA	coat color pattern abdomen	females	1.0 %	1.0
SHIRPA	coat color pattern abdomen	males	12.0 %	0.0550
SHIRPA	coat color pattern abdomen	both	6.0 %	0.0959
SHIRPA	coat color pattern back	females	0.0 %	1.0
SHIRPA	coat color pattern back	males	0.0 %	1.00
SHIRPA	coat color pattern back	both	0.0 %	1.0
SHIRPA	coat color pattern head	females	0.0 %	1.0
SHIRPA	coat color pattern head	males	0.0 %	1.0
SHIRPA	coat color pattern head	both	0.0 %	1.00
SHIRPA	coat hair abdomen texture appearance	females	2.0 %	1.0
SHIRPA	coat hair abdomen texture appearance	males	2.0 %	1.0
SHIRPA	coat hair abdomen texture appearance	both	2.0 %	1.0
SHIRPA	coat hair back texture appearance	females	0.0 %	1.0
SHIRPA	coat hair back texture appearance	males	0.0 %	1.0
SHIRPA	coat hair back texture appearance	both	0.0 %	1.0
SHIRPA	coat hair distribution abdomen	females	0.0 %	1.0
SHIRPA	coat hair distribution abdomen	males	1.0 %	1.00
SHIRPA	coat hair distribution abdomen	both	1.0 %	1.00
SHIRPA	coat hair distribution back	females	0.0 %	1.0
SHIRPA	coat hair distribution back	males	0.0 %	1.0
SHIRPA	coat hair distribution back	both	0.0 %	1.0
SHIRPA	coat hair distribution head	females	1.0 %	1.00
SHIRPA	coat hair distribution head	males	1.0 %	1.0
SHIRPA	coat hair distribution head	both	1.0 %	1.0
SHIRPA	coat hair head texture appearance	females	0.0 %	1.00
SHIRPA	coat hair head texture appearance	males	0.0 %	1.0
SHIRPA	coat hair head texture appearance	both	0.0 %	1.0
SHIRPA	contact righting	females	5.0 %	1.0
SHIRPA	contact righting	males	5.0 %	1.00
SHIRPA	contact righting	both	5.0 %	1.00
SHIRPA	ear morphology	females	0.0 %	1.0
SHIRPA	ear morphology	males	0.0 %	1.0
SHIRPA	ear morphology	both	0.0 %	1.0
SHIRPA	fat distribution	females	0.0 %	1.0
SHIRPA	fat distribution	males	0.0 %	1.0
SHIRPA	fat distribution	both	0.0 %	1.00
SHIRPA	forelimb digit number	females	0.0 %	1.00
SHIRPA	forelimb digit number	males	0.0 %	1.0
SHIRPA	forelimb digit number	both	0.0 %	1.00
SHIRPA	forelimb digit position	females	0.0 %	1.0
SHIRPA	forelimb digit position	males	0.0 %	1.0
SHIRPA	forelimb digit position	both	0.0 %	1.0
SHIRPA	forelimb digit shape	females	0.0 %	1.0
SHIRPA	forelimb digit shape	males	0.0 %	1.0
SHIRPA	forelimb digit shape	both	0.0 %	1.0
SHIRPA	forelimb digit size	females	0.0 %	1.0
SHIRPA	forelimb digit size	males	0.0 %	1.0
SHIRPA	forelimb digit size	both	0.0 %	1.0
SHIRPA	forelimb footpads	females	0.0 %	1.0
SHIRPA	forelimb footpads	males	0.0 %	1.0
SHIRPA	forelimb footpads	both	0.0 %	1.0
SHIRPA	forelimb nail length	females	0.0 %	1.0
SHIRPA	forelimb nail length	males	0.0 %	1.0
SHIRPA	forelimb nail length	both	0.0 %	1.0
SHIRPA	forelimb nail number	females	0.0 %	1.0
SHIRPA	forelimb nail number	males	0.0 %	1.0
SHIRPA	forelimb nail number	both	0.0 %	1.0
SHIRPA	forelimb nail position	females	0.0 %	1.0
SHIRPA	forelimb nail position	males	0.0 %	1.0
SHIRPA	forelimb nail position	both	0.0 %	1.0
SHIRPA	forelimb nail shape	females	0.0 %	1.0
SHIRPA	forelimb nail shape	males	0.0 %	1.0
SHIRPA	forelimb nail shape	both	0.0 %	1.0
SHIRPA	forelimbs position	females	0.0 %	1.0
SHIRPA	forelimbs position	males	0.0 %	1.0
SHIRPA	forelimbs position	both	0.0 %	1.0
SHIRPA	forelimbs shape	females	0.0 %	1.0
SHIRPA	forelimbs shape	males	0.0 %	1.0
SHIRPA	forelimbs shape	both	0.0 %	1.0
SHIRPA	forelimbs size	females	0.0 %	1.0
SHIRPA	forelimbs size	males	0.0 %	1.0
SHIRPA	forelimbs size	both	0.0 %	1.0
SHIRPA	forepaw position	females	0.0 %	1.0
SHIRPA	forepaw position	males	0.0 %	1.0
SHIRPA	forepaw position	both	0.0 %	1.0
SHIRPA	forepaw shape	females	0.0 %	1.0
SHIRPA	forepaw shape	males	0.0 %	1.0
SHIRPA	forepaw shape	both	0.0 %	1.0
SHIRPA	forepaw size	females	0.0 %	1.0
SHIRPA	forepaw size	males	0.0 %	1.0
SHIRPA	forepaw size	both	0.0 %	1.0
SHIRPA	gait (fluidity)	females	0.0 %	1.0
SHIRPA	gait (fluidity)	males	0.0 %	1.00
SHIRPA	gait (fluidity)	both	0.0 %	1.00
SHIRPA	genitalia morphology	females	0.0 %	1.00
SHIRPA	genitalia morphology	males	0.0 %	1.0
SHIRPA	genitalia morphology	both	0.0 %	1.00
SHIRPA	genitalia presence	females	0.0 %	1.0
SHIRPA	genitalia presence	males	0.0 %	1.0
SHIRPA	genitalia presence	both	0.0 %	1.0
SHIRPA	genitalia size	females	0.0 %	1.0
SHIRPA	genitalia size	males	0.0 %	1.0
SHIRPA	genitalia size	both	0.0 %	1.0
SHIRPA	head bobbing	females	0.0 %	1.0
SHIRPA	head bobbing	males	0.0 %	1.0
SHIRPA	head bobbing	both	0.0 %	1.0
SHIRPA	head morphology	females	0.0 %	1.0
SHIRPA	head morphology	males	0.0 %	1.00
SHIRPA	head morphology	both	0.0 %	1.0
SHIRPA	head size	females	0.0 %	1.0
SHIRPA	head size	males	0.0 %	1.0
SHIRPA	head size	both	0.0 %	1.00
SHIRPA	hindlimb digit number	females	1.0 %	1.00
SHIRPA	hindlimb digit number	males	0.0 %	1.0
SHIRPA	hindlimb digit number	both	0.0 %	1.00
SHIRPA	hindlimb digit position	females	0.0 %	1.0
SHIRPA	hindlimb digit position	males	0.0 %	1.0
SHIRPA	hindlimb digit position	both	0.0 %	1.0
SHIRPA	hindlimb digit shape	females	0.0 %	1.0
SHIRPA	hindlimb digit shape	males	0.0 %	1.0
SHIRPA	hindlimb digit shape	both	0.0 %	1.0
SHIRPA	hindlimb digit size	females	0.0 %	1.00
SHIRPA	hindlimb digit size	males	0.0 %	1.0
SHIRPA	hindlimb digit size	both	0.0 %	1.00
SHIRPA	hindlimb nail length	females	0.0 %	1.0
SHIRPA	hindlimb nail length	males	0.0 %	1.0
SHIRPA	hindlimb nail length	both	0.0 %	1.00
SHIRPA	hindlimb nail number	females	0.0 %	1.0
SHIRPA	hindlimb nail number	males	1.0 %	1.0
SHIRPA	hindlimb nail number	both	0.0 %	1.00
SHIRPA	hindlimb nail position	females	0.0 %	1.0
SHIRPA	hindlimb nail position	males	0.0 %	1.0
SHIRPA	hindlimb nail position	both	0.0 %	1.0
SHIRPA	hindlimb nail shape	females	0.0 %	1.0
SHIRPA	hindlimb nail shape	males	0.0 %	1.0
SHIRPA	hindlimb nail shape	both	0.0 %	1.0
SHIRPA	hindlimbs footpads	females	0.0 %	1.0
SHIRPA	hindlimbs footpads	males	0.0 %	1.0
SHIRPA	hindlimbs footpads	both	0.0 %	1.0
SHIRPA	hindlimbs position	females	0.0 %	1.0
SHIRPA	hindlimbs position	males	0.0 %	1.0
SHIRPA	hindlimbs position	both	0.0 %	1.0
SHIRPA	hindlimbs shape	females	0.0 %	1.0
SHIRPA	hindlimbs shape	males	0.0 %	1.0
SHIRPA	hindlimbs shape	both	0.0 %	1.0
SHIRPA	hindlimbs size	females	0.0 %	1.0
SHIRPA	hindlimbs size	males	0.0 %	1.0
SHIRPA	hindlimbs size	both	0.0 %	1.0
SHIRPA	hindpaw position	females	0.0 %	1.0
SHIRPA	hindpaw position	males	0.0 %	1.0
SHIRPA	hindpaw position	both	0.0 %	1.0
SHIRPA	hindpaw shape	females	0.0 %	1.0
SHIRPA	hindpaw shape	males	0.0 %	1.0
SHIRPA	hindpaw shape	both	0.0 %	1.0
SHIRPA	hindpaw size	females	0.0 %	1.0
SHIRPA	hindpaw size	males	0.0 %	1.0
SHIRPA	hindpaw size	both	0.0 %	1.0
SHIRPA	limb grasp	females	16.0 %	0.154
SHIRPA	limb grasp	males	6.0 %	1.0
SHIRPA	limb grasp	both	5.0 %	0.327
SHIRPA	lower lip morphology	females	0.0 %	1.0
SHIRPA	lower lip morphology	males	0.0 %	1.0
SHIRPA	lower lip morphology	both	0.0 %	1.0
SHIRPA	lower teeth appearance	females	0.0 %	1.0
SHIRPA	lower teeth appearance	males	0.0 %	1.00
SHIRPA	lower teeth appearance	both	0.0 %	1.00
SHIRPA	mouth morphology	females	0.0 %	1.0
SHIRPA	mouth morphology	males	0.0 %	1.00
SHIRPA	mouth morphology	both	0.0 %	1.00
SHIRPA	salivation	females	0.0 %	1.0
SHIRPA	salivation	males	0.0 %	1.0
SHIRPA	salivation	both	0.0 %	1.0
SHIRPA	skin color back paws	females	0.0 %	1.0
SHIRPA	skin color back paws	males	0.0 %	1.0
SHIRPA	skin color back paws	both	0.0 %	1.0
SHIRPA	skin color ear	females	0.0 %	1.0
SHIRPA	skin color ear	males	0.0 %	1.0
SHIRPA	skin color ear	both	0.0 %	1.0
SHIRPA	skin color front paws	females	0.0 %	1.0
SHIRPA	skin color front paws	males	0.0 %	1.0
SHIRPA	skin color front paws	both	0.0 %	1.0
SHIRPA	skin color snout	females	0.0 %	1.0
SHIRPA	skin color snout	males	0.0 %	1.0
SHIRPA	skin color snout	both	0.0 %	1.0
SHIRPA	skin color tail	females	0.0 %	1.0
SHIRPA	skin color tail	males	0.0 %	1.0
SHIRPA	skin color tail	both	0.0 %	1.0
SHIRPA	skin color whole body	females	0.0 %	1.0
SHIRPA	skin color whole body	males	0.0 %	1.0
SHIRPA	skin color whole body	both	0.0 %	1.0
SHIRPA	skin texture back paw	females	0.0 %	1.0
SHIRPA	skin texture back paw	males	0.0 %	1.0
SHIRPA	skin texture back paw	both	0.0 %	1.0
SHIRPA	skin texture ear	females	0.0 %	1.0
SHIRPA	skin texture ear	males	0.0 %	1.0
SHIRPA	skin texture ear	both	0.0 %	1.0
SHIRPA	skin texture front paws	females	0.0 %	1.0
SHIRPA	skin texture front paws	males	0.0 %	1.0
SHIRPA	skin texture front paws	both	0.0 %	1.0
SHIRPA	skin texture snout	females	0.0 %	1.0
SHIRPA	skin texture snout	males	0.0 %	1.0
SHIRPA	skin texture snout	both	0.0 %	1.0
SHIRPA	skin texture tail	females	0.0 %	1.0
SHIRPA	skin texture tail	males	0.0 %	1.0
SHIRPA	skin texture tail	both	0.0 %	1.0
SHIRPA	skin texture whole body	females	0.0 %	1.0
SHIRPA	skin texture whole body	males	0.0 %	1.00
SHIRPA	skin texture whole body	both	0.0 %	1.00
SHIRPA	snout size	females	0.0 %	1.0
SHIRPA	snout size	males	1.0 %	1.0
SHIRPA	snout size	both	0.0 %	1.0
SHIRPA	startle response	females	0.0 %	1.00
SHIRPA	startle response	males	0.0 %	1.00
SHIRPA	startle response	both	0.0 %	1.00
SHIRPA	tail curvature	females	0.0 %	1.00
SHIRPA	tail curvature	males	0.0 %	1.0
SHIRPA	tail curvature	both	0.0 %	1.0
SHIRPA	tail elevation	females	1.0 %	1.00
SHIRPA	tail elevation	males	2.0 %	1.0
SHIRPA	tail elevation	both	1.0 %	1.0
SHIRPA	tail length	females	0.0 %	1.0
SHIRPA	tail length	males	0.0 %	1.0
SHIRPA	tail length	both	0.0 %	1.00
SHIRPA	tail morphology	females	0.0 %	1.00
SHIRPA	tail morphology	males	0.0 %	1.0
SHIRPA	tail morphology	both	0.0 %	1.00
SHIRPA	tail presence	females	0.0 %	1.0
SHIRPA	tail presence	males	0.0 %	1.0
SHIRPA	tail presence	both	0.0 %	1.0
SHIRPA	tail shape	females	0.0 %	1.0
SHIRPA	tail shape	males	0.0 %	1.0
SHIRPA	tail shape	both	0.0 %	1.00
SHIRPA	tail thickness	females	0.0 %	1.0
SHIRPA	tail thickness	males	0.0 %	1.0
SHIRPA	tail thickness	both	0.0 %	1.0
SHIRPA	teeth presence	females	0.0 %	1.0
SHIRPA	teeth presence	males	0.0 %	1.00
SHIRPA	teeth presence	both	0.0 %	1.00
SHIRPA	touch escape	females	14.0 %	0.606
SHIRPA	touch escape	males	14.0 %	0.611
SHIRPA	touch escape	both	14.0 %	0.161
SHIRPA	transfer arousal	females	1.0 %	1.0
SHIRPA	transfer arousal	males	2.0 %	1.00
SHIRPA	transfer arousal	both	1.0 %	1.0
SHIRPA	tremor	females	0.0 %	1.0
SHIRPA	tremor	males	0.0 %	1.0
SHIRPA	tremor	both	0.0 %	1.00
SHIRPA	trunk curl	females	0.0 %	1.00
SHIRPA	trunk curl	males	0.0 %	1.0
SHIRPA	trunk curl	both	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	females	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	males	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	both	0.0 %	1.00
SHIRPA	upper lip morphology	females	0.0 %	1.0
SHIRPA	upper lip morphology	males	0.0 %	1.0
SHIRPA	upper lip morphology	both	0.0 %	1.0
SHIRPA	upper teeth appearance	females	0.0 %	1.0
SHIRPA	upper teeth appearance	males	0.0 %	1.0
SHIRPA	upper teeth appearance	both	0.0 %	1.00
SHIRPA	vibrissae appearance	females	2.0 %	1.0
SHIRPA	vibrissae appearance	males	1.0 %	1.0
SHIRPA	vibrissae appearance	both	1.0 %	1.0
SHIRPA	vibrissae presence	females	2.0 %	1.00
SHIRPA	vibrissae presence	males	1.0 %	1.0
SHIRPA	vibrissae presence	both	2.0 %	1.0
SHIRPA	vocalization	females	2.0 %	1.00
SHIRPA	vocalization	males	2.0 %	1.0
SHIRPA	vocalization	both	2.0 %	1.00
tail suspension	climbing, 5 min test (yes, no)	females	22.0 %	0.213
tail suspension	climbing, 5 min test (yes, no)	males	22.0 %	0.212
tail suspension	climbing, 5 min test (yes, no)	both	22.0 %	0.0307

GENOTYPE CORRELATION PLOT

Correlate Adar^{tm1b(EUCOMM)Wtsi} -/+ with genotype: